Mansion holiday rentals in Panama
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Top-rated mansion rentals in Panama
Guests agree: these mansions are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama mansion rentals
Luxury mansion rentals
Serviced apartment in Panama City
4.84 out of 5 average rating, 31 reviewsPenthouse deluxe, 360º views and glass pool
Villa in Panamá
4.98 out of 5 average rating, 49 reviewsBeautiful House in Panama w/ King Beds + Pool
Home in Río Hato
4.95 out of 5 average rating, 75 reviewsEspectacular casa frente al mar en Buenaventura!
Villa in Playa Venao
4.98 out of 5 average rating, 61 reviewsCasa Aqua: Amazing beach front house - Playa Venao
Flat in Maria Chiquita
4.95 out of 5 average rating, 64 reviewsSpacious 4Br Beachside Getaway at Playa Escondida
Flat in Maria Chiquita
4.95 out of 5 average rating, 21 reviewsPenthouse en Playa Escondida 4 recamaras
Villa in Bejuco
4.96 out of 5 average rating, 78 reviewsBeach house at Punta Chame, Villa frente al mar
Villa in Río Hato
4.91 out of 5 average rating, 22 reviewsSecluded Villa in Buenaventura Golf and Resort
Pet-friendly mansion rentals
Villa in Portobelo
5.0 out of 5 average rating, 43 reviewsEntire Villa with pool in front of beach!
Home in Playa Bluff
5.0 out of 5 average rating, 18 reviewsJungle House 100m from the beach
Flat in San Carlos District
4.99 out of 5 average rating, 81 reviewsIncreíble departamento Oceanfront en San Carlos
Home in San Carlos
4.93 out of 5 average rating, 89 reviewsBeach House-Ocean View Rooftop Jacuzzi & Pool
Villa in Panamá
5.0 out of 5 average rating, 32 reviewsBreathtaking Views Mansion w/King Beds
Home in Río Hato
4.98 out of 5 average rating, 99 reviewsRenewed / Make yourself at Home / Enjoy
Apartment in San Carlos District
4.97 out of 5 average rating, 38 reviewsPunta Caelo Beach Front View
Villa in Costa Esmeralda
4.97 out of 5 average rating, 71 reviews#1 Villa con piscina, jacuzzi, billar, pin pon.
Mansion rentals with a pool
Apartment in Maria Chiquita
5.0 out of 5 average rating, 22 reviewsPlaya Escondida Lux Beachfront Haven:Oceanview Apt
Flat in Río Hato
5.0 out of 5 average rating, 19 reviews4 Bedroom Private Pool Paradise in Buenaventura
Flat in Panamá
5.0 out of 5 average rating, 22 reviewsTop Floor Condo 6 bedroom with amazing views
Home in Gamboa
4.86 out of 5 average rating, 88 reviewsBirdHouse@ Gamboa Panamá Canal
Home in Pedasí
4.83 out of 5 average rating, 6 reviewsOcean View From The Jungle!
Flat in Panama City
4.95 out of 5 average rating, 19 reviews22M Spectacular Penthouse New Design Oceanview
Home in Bastimentos
4.8 out of 5 average rating, 99 reviewsSpacious, Over the Water Home with Plunge Pool
Flat in El Chirú
4.94 out of 5 average rating, 85 reviewsBuenaventura Golf & Beach Resort Lux Apartment
Destinations to explore
- Bed and breakfasts Panama
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- Rentals with an EV charger Panama
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- Rentals with a washing machine and dryer Panama
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- Serviced apartment rentals Panama
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