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Guest house holiday rentals in DoƱa Ana County

Find and book unique guest house rentals on Airbnb

Top-rated guest house rentals in DoƱa Ana County

Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

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Top guest favourite
Guest house in Las Cruces
4.96 out of 5 average rating, 229 reviews

Quaint casita for 2

*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

Top guest favourite
A spacious entryway leads into a cozy living area featuring a green couch and a round wooden coffee table. Light-colored flooring and soft lighting create a bright ambiance. A small dining area with two black stools is visible beside a wooden countertop, adorned with potted plants.
Guest house in El Paso
4.97 out of 5 average rating, 385 reviews

Cozy Modern Casita-Studio!

Perfectly located in Central El Paso! Found near the Franklin Mountain range, Downtown El Paso, great restaurants, sporting arenas, multiple hospitals, Fort Bliss Army base, and much more! Conveniently near multiple freeways for quick access to surrounding locations! -Newly renovated -Equipped with new modern appliances -Washer and dryer -Refrigerated air and heating -Comfortable queen bed -Sleeper sofa to accommodate a 3rd guest or children -Pack n’ play available for extra fee by request

Top guest favourite
A welcoming porch features two light blue chairs positioned beside a rustic table under a wooden beam ceiling. A ceiling fan hangs above, and a colorful door adds a touch of character. A dried chili pepper wreath decorates the entryway, enhancing the outdoor oasis.
Guest house in Las Cruces
5 out of 5 average rating, 236 reviews

Ocotillo Casita in Historic Mesilla.

Mesilla STR Permit #0830 We've renovated 90-year-old historic structures to create sustainable, environmental friendly spaces with rainwater harvesting, solar energy, electric solar-powered car charger. This renovated adobe casita is the 2nd structure after our main house. The 3rd is a smaller vacation rental called Yucca Casita. We are within 2 blocks of the historic Mesilla plaza with its farmers market, shops, galleries, restaurants, and walking trails along historic acequias (canals).

Top guest favourite
The kitchen features blue cabinetry and colorful Talavera tile backsplash, enhancing its visual appeal. A window allows natural light to illuminate the space, while stainless steel appliances, including a microwave and dishwasher, are present. Wood countertops provide a warm contrast to the cabinetry.
Guest house in Las Cruces
4.96 out of 5 average rating, 144 reviews

1 king bd with big fenced back yard pets welcome

Casita La Pacana is nestled in the middle of town surrounded by old pecan trees. Feels like the country but is in the middle of town. 1 bedroom, completely renovated casita that has 1 kind bed, a large living room, streaming TVs in both living room and bedroom, full kitchen including a dishwasher and washer/dryer, hardwood floors, authentic Talavera tile, large shower with a bench seat, huge back yard, and ample parking! This little casita has everything to be your home away from home.

Top guest favourite
A vibrant yellow casita is framed by a rocky landscape and native vegetation. Large windows and a covered porch are visible, inviting natural light. The casita's exterior showcases a blend of rustic charm and modern design, set against a clear blue sky.
Guest house in Las Cruces
4.98 out of 5 average rating, 194 reviews

Raven's House

Casita De Cuervo is a beautiful detached casita. This spacious & quiet casita is very close to popular hiking trails and feels remote while being less than 15 minutes from I-25, NMSU, and both hospitals. This home has a full kitchen, king bed, open living room, work nook, bar stool dining, & much more. Dogs are welcome - there is an enclosed side yard with tall walls for your use. Enjoy the sunrise over the Organ Mountains on the back porch and breathtaking sunset views over the city.

Top guest favourite
The entrance features a traditional adobe archway with purple wooden doors flanked by a rustic ladder. A lantern hangs above the opening, while desert vegetation is visible to one side. The backdrop includes distant mountains under a clear blue sky.
Guest house in Las Cruces
5 out of 5 average rating, 277 reviews

Desert Peaks Casita

This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

Top guest favourite
Guest house in El Paso
4.95 out of 5 average rating, 140 reviews

The Calm Landing - Private stay 5 min from airport

The Calm Landing – Peaceful Stay Near Airport & Park Private studio **NO CLEANING FEE** Discover a quiet retreat just 5 minutes from El Paso Airport. This serene studio offers a private entrance, easy parking, and a calming minimalist design. Step outside to a peaceful neighborhood park just feet away, or relax indoors in your own cozy space. Whether you're here to unwind, recharge, or explore the area, this tranquil hideaway feels like home from the moment you arrive.

Top guest favourite
A cozy interior space features a queen bed with a bright yellow throw pillow. A kitchenette with a microwave, mini-fridge, and sink is present. Natural light filters through the windows, which are adorned with blue curtains. A small table and chairs complement the room's design.
Guest house in Las Cruces
4.97 out of 5 average rating, 359 reviews

Cozy Casita w/private patio near Old Mesilla

This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Top guest favourite
A private hot tub is positioned under a wooden pergola with string lights, creating a serene outdoor space. The area features a fire pit nearby, with a scenic view of mountains and city lights visible in the background, illuminated at dusk.
Guest house in El Paso
4.91 out of 5 average rating, 194 reviews

Private studio w/ scenic view near downtown

Relax in this cozy studio apartment attached to a beautiful home with access to hot tub and abundant scenic views. Nestled in the Franklin mountains, you can enjoy hiking trails and the famous Scenic Drive. A 2-minute drive to downtown you will find authentic cuisine and nightlife. Close to UTEP, hospitals and international bridge, this property is located in the heart of the city. Free parking, Wi-Fi, and coffee bar with many selections!

Top guest favourite
A charming casita features a turquoise door and a light exterior, framed by subtle landscaping. The sky is filled with vibrant orange and yellow hues as the sun sets, creating a striking contrast against the white walls and windows.
Guest house in Las Cruces
4.99 out of 5 average rating, 216 reviews

Cozy Casita De Mesilla (Mesilla Cottage)

Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Top guest favourite
The historic Old Spanish Mission building is illuminated against a twilight sky, showcasing its unique architectural features. The white stucco exterior is complemented by natural landscaping and a gravel driveway, inviting guests to explore the surrounding area.
Guest house in Hatch
4.95 out of 5 average rating, 102 reviews

Historic Mission - Priest's Quarters-1BR, 1Bath

Located near Hatch, New Mexico...the Chile Capital of the World...is an Old Spanish Mission built in 1860. St Francis de Sales stopped being an active church in 1963, but still retains its special flavor unique to southwest New Mexico. Come stay in the Colorado Room located within the Rectory (priest's quarters) on the property. Everyone enjoys a one-of-kind experience here. You will, too.

Top guest favourite
A warm sleeping area features a queen bed with a neutral quilt and accent pillows. Two bedside lamps illuminate the space with soft light. The ceiling showcases rustic wooden beams, while a framed artwork hangs above the bed, complemented by a textured area rug beneath.
Guest house in Las Cruces
4.94 out of 5 average rating, 141 reviews

Rustic Downtown Hideaway

This Rustic guest home has all the amenities, 1 Queen bed, couch sleeps small person or child, and walk-in shower. Inspired by the old west, this guest home has reclaimed wood and tin roof from an old barn in New Mexico. Within walking distance to cafes, restaurants, bars, and shops. Easy private access, keyless entry, and off street parking.

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