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Guest house holiday rentals in Doña Ana County

Find and book unique guest house rentals on Airbnb

Top-rated guest house rentals in Doña Ana County

Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

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Top guest favourite
The exterior of the casita is visible, featuring a well-maintained garden with gravel and low shrubs. A terracotta-tiled roof complements the light-colored walls. The private entrance is highlighted by a decorative gate, and a clear blue sky creates a bright backdrop.
Guest house in Las Cruces
4.96 out of 5 average rating, 251 reviews

Quaint casita for 2

*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

Guest favourite
A fenced outdoor area features colorful planters and a vibrant mural on the wall. Adirondack chairs are arranged around the space, with a small ladder leaning against the structure. A pathway bordered by rocks leads through an inviting desert landscape.
Guest house in Las Cruces
4.88 out of 5 average rating, 313 reviews

Studio Casita 5 mins to Farmer's mkt/dogs welcome!

We welcome you to our cozy guest house in the heart of Downtown Las Cruces. Perfect for overnights with dogs or kiddos! Close to shopping, the Farmer's Market, and centrally located to enjoy all Las Cruces has to offer. You will have a private entrance, off-street parking, and a fenced yard to yourself. There is a queen bed and a pack-n-play as requested. There is a small kitchenette with a fridge, microwave, sm hot plate, and sink and the casita is equipped with utensils and the basics for you.

Top guest favourite
Guest house in El Paso
4.97 out of 5 average rating, 413 reviews

Cozy Modern Casita-Studio!

Perfectly located in Central El Paso! Found near the Franklin Mountain range, Downtown El Paso, great restaurants, sporting arenas, multiple hospitals, Fort Bliss Army base, and much more! Conveniently near multiple freeways for quick access to surrounding locations! -Newly renovated -Equipped with new modern appliances -Washer and dryer -Refrigerated air and heating -Comfortable queen bed -Sleeper sofa to accommodate a 3rd guest or children -Pack n’ play available for extra fee by request

Top guest favourite
A welcoming porch features two light blue chairs positioned beside a rustic table under a wooden beam ceiling. A ceiling fan hangs above, and a colorful door adds a touch of character. A dried chili pepper wreath decorates the entryway, enhancing the outdoor oasis.
Guest house in Las Cruces
5 out of 5 average rating, 248 reviews

Ocotillo Casita in Historic Mesilla.

Mesilla STR Permit #0830 We've renovated 90-year-old historic structures to create sustainable, environmental friendly spaces with rainwater harvesting, solar energy, electric solar-powered car charger. This renovated adobe casita is the 2nd structure after our main house. The 3rd is a smaller vacation rental called Yucca Casita. We are within 2 blocks of the historic Mesilla plaza with its farmers market, shops, galleries, restaurants, and walking trails along historic acequias (canals).

Top guest favourite
A inviting hot tub is surrounded by wooden fencing, providing privacy and a sense of seclusion. The serene view of the desert landscape and mountains is visible in the background, complementing the peaceful atmosphere of the outdoor space.
Guest house in Las Cruces
5 out of 5 average rating, 287 reviews

Desert Peaks Casita

This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

Top guest favourite
A tranquil sleeping area features a spacious bed adorned with decorative pillows and a handwoven wall hanging above. Soft lighting from an ornate chandelier complements the adobe walls, while a rustic table and chairs anchor the inviting space.
Guest house in Las Cruces
4.97 out of 5 average rating, 356 reviews

Clara's Nest - The Gem of Hacienda de Las Cruces

Clara’s Nest is in a 1880's adobe compound with its own private entry, courtyard, original stone floors, handcrafted beams, hand-painted bird & flower motif throughout. The suite features a king bed, cozy loveseat & ottoman in the sleeping area, dining table & 4 chairs, kitchenette with micro, fridge, coffee & tea bar, a separate living room with sofa, TV, private bath. Outer space includes: covered patio, backyard, pool and hot tub area (heated upon request) No stove.

Top guest favourite
Guest house in Las Cruces
4.97 out of 5 average rating, 375 reviews

Cozy Casita w/private patio near Old Mesilla

This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Top guest favourite
A private hot tub is positioned under a wooden pergola with string lights, creating a serene outdoor space. The area features a fire pit nearby, with a scenic view of mountains and city lights visible in the background, illuminated at dusk.
Guest house in El Paso
4.92 out of 5 average rating, 222 reviews

Private studio w/ scenic view near downtown

Relax in this cozy studio apartment attached to a beautiful home with access to hot tub and abundant scenic views. Nestled in the Franklin mountains, you can enjoy hiking trails and the famous Scenic Drive. A 2-minute drive to downtown you will find authentic cuisine and nightlife. Close to UTEP, hospitals and international bridge, this property is located in the heart of the city. Free parking, Wi-Fi, and coffee bar with many selections!

Top guest favourite
Guest house in Las Cruces
4.99 out of 5 average rating, 239 reviews

Cozy Casita De Mesilla (Mesilla Cottage)

Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Top guest favourite
The historic Old Spanish Mission building is illuminated against a twilight sky, showcasing its unique architectural features. The white stucco exterior is complemented by natural landscaping and a gravel driveway, inviting guests to explore the surrounding area.
Guest house in Hatch
4.95 out of 5 average rating, 110 reviews

Historic Mission - Priest's Quarters-1BR, 1Bath

Located near Hatch, New Mexico...the Chile Capital of the World...is an Old Spanish Mission built in 1860. St Francis de Sales stopped being an active church in 1963, but still retains its special flavor unique to southwest New Mexico. Come stay in the Colorado Room located within the Rectory (priest's quarters) on the property. Everyone enjoys a one-of-kind experience here. You will, too.

Top guest favourite
Guest house in Las Cruces
4.94 out of 5 average rating, 190 reviews

Rustic Downtown Hideaway

This Rustic guest home has all the amenities, 1 Queen bed, couch sleeps small person or child, and walk-in shower. Inspired by the old west, this guest home has reclaimed wood and tin roof from an old barn in New Mexico. Within walking distance to cafes, restaurants, bars, and shops. Easy private access, keyless entry, and off street parking.

Top guest favourite
The exterior of a single-story casita is shown, featuring a light pink stucco facade and a red-tile roof. A gated entrance is visible, along with a small lawn and a concrete walkway leading to the door. A garage door is also seen on the left.
Guest house in Las Cruces
4.96 out of 5 average rating, 1,157 reviews

Cozy Casita with Patio

Cozy casita (guest house) with patio in nice quiet neighborhood close to NMSU, Convention center, Memorial Hospital, Mountain View Hospital, Old Mesilla, ,wine country, shopping, convenient to White Sands, hiking, etc. Casita has private entrance, private bath, small refrigerator, TV, coffee maker, microwave, and wifi

Popular amenities for guest house rentals in Doña Ana County