Guest house holiday rentals in Greenville County

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Top-rated guest house rentals in Greenville County

Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

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Top guest favourite
Guest house in Mauldin
4.9 out of 5 average rating, 248 reviews

Pet friendly•family. Private Entry•Fire Pit.

Welcome to your private and cozy guest house, The perfect space for couples, small families, or pet owners looking for comfort, privacy, and a relaxing stay You’ll love staying here because it’s the perfect mix of comfort, privacy, and charm. Whether you’re relaxing by the fire pit, enjoying the peaceful outdoor space, or unwinding inside with all the comforts of home, this cozy retreat offers everything you need for a relaxing stay. Plus, located in a quiet neighborhood close to everything!!

Top guest favourite
A charming log cabin is nestled among lush greenery, featuring wooden walls and a sloping roof. The front door is framed by two windows adorned with flower boxes. Two white chairs sit on a stone pathway, inviting relaxation in the serene outdoor setting.
Guest house in Greenville
4.93 out of 5 average rating, 711 reviews

Historic 19th Century Cabin/Guest House

This 19th century cabin is your perfect cozy getaway. This guest house is located on a 3.5 acre property, secluded from the historic neighborhood, though it's just 3 miles from downtown Greenville and the Bon Secours Wellness Arena. Less than a mile to the Swamp Rabbit Trail, this cottage is perfect for jaunts to downtown Greenville, Furman University, Paris Mountain, Travelers Rest and Unity Park! Micro weddings and events are available upon request and approval with applicable fees applied.

Guest favourite
A detached garage studio is shown from the side, featuring a staircase leading to the main entrance. The exterior is clad in light gray siding, accented by dark trim around the windows. A white garage door is visible at the base, complemented by surrounding greenery.
Guest house in Greenville
4.97 out of 5 average rating, 158 reviews

Nishleigh's Nook - West End Downtown Greenville

Welcome to your cozy retreat in the West End of Downtown Greenville! This newly constructed, detached garage studio near the up and coming West End Village, Unity Park, and downtown offers easy access to the city's best entertainment, boutique shops, and vibrant food scene. Enjoy a queen-sized memory foam bed, a fully equipped kitchen, and a dedicated dining area. High-speed Wi-Fi and a smart TV are included. Perfect for a peaceful escape with all the comforts you need for a memorable stay.

Top guest favourite
The serene cottage is surrounded by lush greenery and colorful flowers, with pink azaleas and white dogwoods blooming prominently in the foreground. A charming red barn is nestled among the trees, enhancing the peaceful rural setting.
Guest house in Greenville
5 out of 5 average rating, 446 reviews

The Cottage at Old Oaks Farm

Built in the early 1900's, this serene cottage is located approximately one mile from Furman University at the base of Paris Mt. It has been lovingly improved, but the floors are a bit slanted and no corner is exactly square. Located in a neighborhood on a five acre farm, it consists of three large rooms, comfortably furnished and lots of natural light. The cottage is convenient to downtown Greenville(5 miles),Travelers Rest, Furman, and the Swamp Rabbit Trail. No pet fee or cleaning fee.

Top guest favourite
An archway leads to a narrow passage, flanked by white brick walls, with exposed brick adding texture. Warm lighting from overhead fixtures illuminates the space. On the ground, patterned red and brown bricks create a welcoming path, complemented by decorative lanterns placed nearby.
Guest house in Greenville
4.94 out of 5 average rating, 235 reviews

Gorgeous Downtown Studio & Dog Friendly!

This has moved to 30 days+ starting Jan 2024! Message me if you're trying to book and your dates aren't showing available! This location is unmatched. Steps from Falls Park which includes one of the most majestic waterfalls, green space and Swamp Rabbit Trail for all your running/walking and biking needs. Directly across the street from the Greenville Drive baseball stadium. One block from all the finest restaurants, shopping and best attractions downtown offers.

Top guest favourite
An inviting pool deck features a clear swimming pool with a diving board, overlooking a vast mountainous vista. The scene is framed by leafless trees and potted plants, while the sky displays soft, fluffy clouds and bright blue patches.
Guest house in Greenville
4.97 out of 5 average rating, 263 reviews

Greenville With A View!

ONLY 10-15 MINUTE DRIVE TO THE HEART OF BEAUTIFUL DOWNTOWN GREENVILLE! We are only 11 miles to GSP Airport; 6 miles to Greenville Downtown Airport; and 10 minutes to the Swamp Rabbit Trail. We are minutes to Furman University, Bob Jones University, North Greenville University and Clemson University is only 45 minutes away. We are tucked away open top of Paris Mountain. If you want to bike, hike, paddle, swim, boat or just soak it all in, start here!

Top guest favourite
The open living area features a striped armchair facing a wooden coffee table. A kitchen with white cabinetry and a breakfast bar is seen in the background, equipped with modern appliances and natural lighting from multiple windows.
Guest house in Simpsonville
4.95 out of 5 average rating, 267 reviews

Private Suite in Downtown Simpsonville

Cozy 1 bed/1 bath apartment in downtown Simpsonville. With this private single unit above a garage used for storage only, you do not share walls with anyone! You are within walking distance to restaurants & shopping! This private unit is a rare find for the price!! As you pull into your own parking space, you overlook a private yard. ***Please note there is a train near the home that runs once midday and once late at night.

Top guest favourite
The exterior of the property is shown, featuring yellow siding complemented by dark shutters on the windows. A single door with glass panels is visible, providing a welcoming entrance. A grassy area is located at the base of the wall, enhancing the outdoor setting.
Guest house in Liberty
4.93 out of 5 average rating, 209 reviews

Holly Hideaway! 10 Highway miles to Clemson U!

Holly Hideaway is nestled between Greenville and Clemson, in the small town of Liberty. It's perfect for business travelers, couples, Clemson parents, alumni, and small families. Tiled throughout for cleanliness. Privacy, tranquility, and clean, comfortable accommodations are what we provide. We are 10 minutes from Clemson and 3 miles from SWU. The Hideaway now offers Wi-Fi and Smart TV.

Guest favourite
The exterior view of the Shou-Sugi-Ban Guest House features a dark wooden facade with a sloped roof. A spacious deck is present, furnished with two orange chairs and a potted plant. Lush greenery surrounds the area, providing a natural feel.
Guest house in Piedmont
4.98 out of 5 average rating, 124 reviews

Shou-Sugi-Ban Retreat on the Saluda River

The Shou-Sugi-Ban Guest House is 5 miles from Greenville city center and West Greenville, yet you'll feel like you've escaped it all with the rush of the river and surrounding trees. This cozy, custom space has a king-size bed, and two sets of French doors leading out to a private deck. No matter where you are in the space, you'll have views of the 700 ft of Saluda river frontage.

Top guest favourite
A charming cottage is set among lush greenery, featuring a spacious deck that extends from the front. Large windows provide natural light, while surrounding trees and plants create a serene atmosphere.
Guest house in Greenville
5 out of 5 average rating, 168 reviews

Sally's Cottage

Couples retreat located 6 miles from downtown Greenville and the Swamp Rabbit Trail in a comfortable country setting. Wake up to a beautiful woods view through a large bay window and wildlife that surrounds the cottage (deer, birds and squirrels). Experience the beauty of the country in the city! Enjoy the eclectic collection of art and design in this cute little cottage.

Guest favourite
The exterior of a modern detached guest house is illuminated at night, featuring large windows and a welcoming porch with two chairs. Soft lighting enhances the architectural lines, while greenery and a wooden fence create a peaceful outdoor environment.
Guest house in Travelers Rest
4.96 out of 5 average rating, 134 reviews

Modern guesthouse in downtown TR

Steps from the Swamp Rabbit Trail, Tandem Coffee, Topsoil and more! Enjoy a stylish, relaxed stay at our centrally-located place. Whether you're an outdoor enthusiast or fun-loving foodie, you'll find something just for you nearby. Only a short drive to downtown Greenville, Furman University or Paris Mountain. Within an hour drive of Asheville and Clemson University!

Top guest favourite
Guest house in Greenville
4.96 out of 5 average rating, 240 reviews

The Biltmore Suite

This newly built in-law suite is in a wonderful location just half a mile from the Swamp Rabbit trail and downtown Greenville's Falls Park. The apartment includes 2 parking spots, and additional street parking about a block away. Long term stays available; inquire for pricing. Please not we cannot acquire pets, even service animals, due to an owner allergy!

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