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Holiday rentals in Mesopotamia

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Mesopotamia

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
An aerial view showcases a secluded property surrounded by greenery, softly illuminated by outdoor lights at dusk. The house is positioned on a hill, while paths lead to small seating areas enhanced by tropical plants. The inviting layout suggests a peaceful retreat.
Cabin in Peñol
4.9 out of 5 average rating, 103 reviews

Cabin with jacuzzi and view of the reservoir, 8 people

Take it easy at this unique and tranquil getaway. This house in a subdivision with 3 spacious rooms, a Jacuzzi, a barbecue, access to the dam, and a stunning view of the Peñol stone ★"My wife explored the options and feels that your beautiful villa is her favorite in El Peñol." - Marcela, September 15 Exclusive condominium with few houses which will provide security during your stay, large terrace for your meetings and enjoyment with family or friends. Very safe and comfortable place Newly furnished☞ house.

Superhost
Cabin in Rionegro
4.86 out of 5 average rating, 77 reviews

The Ultimate Group House w/ Hot Tub & Amazing View

About this space 🌟 2 bedrooms, each with a double bed & private bathroom 🛏️ Double sofa bed in the living room 🛋️ Bathrooms with hot water & fresh towels 🚿 Living room with Smart TV & WiFi 📺 Private jacuzzi for relaxation 💦 Fully equipped kitchen 👩‍🍳 Ninja Foodi electric grill for cookouts 🍖 Catamaran net, dining table & spacious deck/terrace 🌞 Private parking space 🅿️ Portable heater available 🔥 Breakfast can be ordered via Rappi (delivery app). We can assist with your order 🍳

Top guest favourite
Tiny home in Cocorná
5 out of 5 average rating, 49 reviews

lovely cabin with sauna, jacuzzi and private river

Enjoy the beautiful nature and tranquility of this luxurious accommodation with a sauna, jacuzzi, and private river terrace. Just 75 minutes from Medellín, this beautiful cabin is easily accessible by any car or motorcycle. The spectacular surroundings of Cocorná have much to offer, including paragliding, rafting, quad biking, and hiking trails along beautiful rivers. We are happy to assist you with transport or activities. We offer private transport from the airport! Includes breakfast!

Top guest favourite
A modern cabin is positioned on a hillside, surrounded by lush greenery and offering panoramic views of the surrounding landscape, including a prominent rock formation and a serene body of water in the foreground.
Tiny home in Guatape
4.98 out of 5 average rating, 642 reviews

Foresta: Modern cabin overlooking the Rock

FORESTA is a modern cabin created with love for you to have an unforgettable stay in the middle of nature, with total comfort. Enjoy the privileged views from the deck, chill out in the jacuzzi, watch the dozens of birds that visit us, or have a chat by the fireplace in the living room. FORESTA is a great launchpad to explore Guatape, climb the Rock and do kayaking, jet-skiing, wakeboarding, sailing, paraglading, horseback riding, hiking, helicopter tours or ATV rides. You choose!

Top guest favourite
Home in Medellín
4.99 out of 5 average rating, 119 reviews

Casa Alba Luxury Villa-Pool-15min to Provenza

1. Luxury Retreat: Unparalleled seclusion in Medellin. 2. Stunning Views: Overlooking Poblado 3. Privacy: Total escape from daily life. 4. Convenient Access: Easy access to the airport. 5. Heated Pool: Year-round relaxation. 6. Jacuzzi: Private and calming atmosphere. 7. Outdoor Amenities: Fireplace & kitchen for al fresco dining. 8. Air Conditioning: Each bedroom offers AC 9. Nightlife: Close to vibrant city nightlife. 15mins drive 10. Daily housekeeping

Top guest favourite
Flat in El Peñol
4.99 out of 5 average rating, 107 reviews

Welcome to Ecolodge Paradise at Montecielo

Escape to tranquility in this serene mountain hideaway overlooking the sparkling waters of one of Colombia's most beautiful lakes. Nestled in the lush hills of Guatapé, our cozy retreat offers breathtaking panoramic views, fresh mountain air, and the perfect setting to unwind and recharge. Wake up to birdsong and misty sunrises, sip your morning coffee on the terrace, and spend your days exploring the vibrant town of Guatapé or simply relaxing in the peaceful embrace of nature.

Top guest favourite
Cabin in Rionegro
5 out of 5 average rating, 33 reviews

Selvva suites | luxury cabin in a forest + jacuzzi

Escape to SELVVA SUITES, a luxury retreat immersed in the tranquility of a native forest, just 50 minutes from Medellín. Located on the Llanogrande–La Ceja road, only 15 minutes from Llanogrande mall and 20 minutes from JMC Airport in Rionegro. Enjoy a King-size bed and a private jacuzzi surrounded by nature. Private parking with easy access for any type of vehicle. ⚠️ ✈️We are in an area with air traffic, and airplane noise can be heard. 🐾 Pet friendly

Top guest favourite
A charming chalet is depicted beside a serene natural lake, framed by lush greenery and vibrant aquatic plants. The structure features rustic wooden details, large windows, and an expansive deck, inviting outdoor relaxation and enjoyment of the tranquil surroundings.
Cabin in Santa Elena
4.99 out of 5 average rating, 180 reviews

Chalet del Lago | Private Jacuzzi + Nature

🌿 Chalet del Lago – Santa Elena Escápate a un refugio natural con lago privado, amplios ventanales y un entorno lleno de paz. Con un muy completo equipamiento y distribución.A solo 10 minutos del parque principal, disfruta del canto de las aves, el sonido del agua y el clima fresco del campo antioqueño. Ideal para parejas, familias o una escapada de descanso. Naturaleza, tranquilidad y momentos inolvidables en un solo lugar. 💛✨ ✅ Somos pet friendly🐶🐈

Top guest favourite
Farm stay in Cocorná
4.98 out of 5 average rating, 43 reviews

Bali-style cabin with forest and private river

Bali-style cabin with more than 2 hectares of private forest and river, hot Jacuzzi, wifi, spring climate, combining luxury and nature, deck next to the river, campfire, cinema-type video projector, shower with a view of nature, work and reading area, beautiful night lighting, kitchen and BBQ area, sun loungers and many other details designed to give you a unique experience and invite you to slow down and reconnect with yourself and nature

Top guest favourite
Cabin in Rionegro
4.98 out of 5 average rating, 107 reviews

Nature & View | Cabin with Jacuzzi and Nature

Enjoy an unforgettable experience in our private cabin, located just 8 minutes from José María Córdova International Airport. Enjoy a panoramic view of the city and relax in your private Jacuzzi. The cabin is equipped with a full kitchen, fast wifi, workspace and self check-in. You will find several nearby restaurants with home delivery, and inside the accommodation we have drinks and snacks to buy. 🚘 Trusted Uber driver

Guest favourite
Cabin in El Peñol
4.95 out of 5 average rating, 143 reviews

Sun Palm Cabin: Nature and Comfort in El Peñol!

Discover an exceptional retreat surrounded by nature, where every detail is designed to offer you an unforgettable experience. This cabin combines elegance and comfort. Relax in your private jacuzzi while enjoying breathtaking panoramic views in a serene environment. Perfect for a romantic getaway or rejuvenating vacation, you will find the ideal harmony between privacy and natural beauty. Your perfect escape awaits!

Guest favourite
Farm stay in Rionegro
4.95 out of 5 average rating, 301 reviews

Lumberjack's House | Secluded nature retreat

🪓 Retiro Cabin – Casa del Leñador is the house of our dreams. A small, cozy tiny home surrounded by nature. The perfect place to spend a few days as a couple, a family weekend, or work remotely in an environment without distractions. Wake up to birdsong at dawn and enjoy a campfire on the deck at dusk. At Retiro Cabin you will have total independence and an unparalleled view of the countryside in eastern Antioquia.

Popular amenities for Mesopotamia holiday rentals

  1. Airbnb
  2. Colombia
  3. Antioquia
  4. Mesopotamia