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Holiday rentals in Mesopotamia

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Mesopotamia

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
A spacious wooden bedroom features a king bed adorned with light bedding, complemented by textured walls and a rustic wood ceiling. A colorful hammock hangs across the room, and natural light filters in through a window, enhancing the cozy ambiance.
Treehouse in Retiro
4.89 out of 5 average rating, 113 reviews

A wooden cabin in the El Retiro Antioquia forest

Imagine sleeping in a wooden cabin in a king-size bed with the lull of the river's sound. When you wake up you will feel like you are in a treehouse overlooking the snowflakes full of birds, going down to the garden with bare feet, having breakfast on the deck and seeing the horizon. During the day, walk, go to the river and the waterfall, get to the stone bathroom and the whirlpool, sit in the hammock, read, and at night light the fireplace (salamander), have a glass of wine at the kitchen counter with your partner, family, and friends.

Top guest favourite
A modern structure emerges from lush greenery, framed by vibrant plants and a manicured lawn. Large glass doors lead to a spacious deck, offering a view of the mountains and a colorful sky. Pathway stones create a welcoming entrance.
Home in La Ceja
4.94 out of 5 average rating, 54 reviews

Country house, excellent location, beautiful view!

Te invitamos a disfrutar de un hermoso espacio rodeado de naturaleza, con todas las comodidades para que puedas relajarte y descansar. Te sentirás como en casa. Lugar ideal para hacer teletrabajo (nómadas digitales) y estancias largas. A tan solo 10 minutos de La Ceja, 45 minutos del aeropuerto internacional y a una 1 hora de Medellín. Mascotas son bienvenidas. Adicionalmente ofrecemos clases de Yoga, terapias Ayurvedicas (Abhyanga/Swedana), clases de tenis. Lugar perfecto para turismo "slow"!

Top guest favourite
The exterior of the house features a modern design, surrounded by lush greenery and trees. A wooden deck area is furnished with comfortable seating, framed by landscaped plants, inviting relaxation in a serene natural setting.
Cabin in San José
4.96 out of 5 average rating, 244 reviews

"Tierra Grata" House in Rionegro-Antioquia

This house has respected the environment in which it was created. With a forest around, you can see many kind of birds and squirrels, it is a space surrounded by nature, quiet, where you can rest. You have comfortable spaces. The cabin consists of 1 room with a double bed. 1 large bathroom, dining room and a teak deck. Totally equiped. From here, you can go visit Guatapé and Peñol stone (1 hour), the ceramics of Carmen de Viboral (45min), the Arvi park in Santa Elena (45 min) and Llanogrande.

Top guest favourite
An outdoor deck area features a hammock hanging beside a small jacuzzi, complemented by a dining table for four. Large sliding doors provide a view into the interior space, where a cozy atmosphere is highlighted by warm lighting and natural wood elements.
Villa in Rionegro
4.95 out of 5 average rating, 177 reviews

Sweet Helen Llanogarden

Sweet Helen Llanogarden situado en el Tablazo-Llanogrande, a tan solo 10 minutos del aeropuerto internacional José Maria Córdova de Rionegro Antioquia, cerca a restaurantes, centros de eventos y malls, en el cual ofrecemos servicios de alojamiento para familias, amigos, parejas y viajes de negocios. En Sweet Helen Llanogarden encontrarás el espacio para pasar una estancia segura, tranquila y divertida, esta vez, rodeada de naturaleza y confort en la zona más exclusiva del oriente antioqueño.

Top guest favourite
Tiny home in Cocorná
5 out of 5 average rating, 37 reviews

luxury cabin with sauna, jacuzzy and private river

Enjoy the beautiful nature and tranquility of this luxurious accommodation with a sauna, jacuzzi, and private river terrace. Just 75 minutes from Medellín, this beautiful cabin is easily accessible by any car or motorcycle. The spectacular surroundings of Cocorná have much to offer, including paragliding, rafting, quad biking, and hiking trails along beautiful rivers. We are happy to assist you with transport or activities. We offer private transport from the airport! Includes breakfast!

Top guest favourite
Cabin in Rionegro
5 out of 5 average rating, 26 reviews

luxury cabin in a native forest

Escape to Selvva Suites a luxury home nestled within a native forest just 50 mins from Medellín ,offering an exclusive experience. Located on the Llanogrande–La Ceja road. King-size bed, jacuzzi, fully equipped kitchen, bathroom with hot water, Wi-Fi, 65” Smart TV, and a surround sound system. Private parking with easy access for all types of vehicles. ⚠️ ✈️ The property is located in an area with air traffic; aircraft noise may be noticeable. 🐾 Pet-friendly (house rules apply)

Guest favourite
Cabin in El Carmen de Viboral
4.95 out of 5 average rating, 64 reviews

Espi Ritual

Step into tranquility and reconnect with nature in this serene Llano Grando cabin. Soak up the patio sun, immerse yourself in the beautiful garden, or spot countless bird species on the sun-deck overlooking the pond. This cabin is equipped with WiFi, a full kitchen, an asador, and a private entrance. The perfect location for a peaceful solo trip, charming romantic getaway, or unique family adventure. 15 minutes from charming San Antonia and near restaurants and shopping

Top guest favourite
Cabin in Rionegro
4.95 out of 5 average rating, 330 reviews

Nature & View | Cabin with a View

Nature & View just 8 min from JMC Airport Ideal for couples or travelers in transit. Our cabin offers a view of the valley, a quiet atmosphere, self check-in, an equipped kitchen, fast wifi, and all the comforts to relax. For your convenience, there are restaurants with home delivery and inside the accommodation you can buy cold drinks and snacks when you need them. 🚘 Trusted Uber driver Relax, order your favorite food and enjoy the view. Book your date!

Top guest favourite
A single-story house surrounded by lush greenery is showcased. The exterior features a welcoming porch with seating and a hammock. The structure boasts large windows for natural light, while landscaped bushes and trees frame the property, enhancing the serene rural setting.
Farm stay in El Carmen de Viboral
4.97 out of 5 average rating, 106 reviews

☼♥Villa Serena ♥☼ 360° Views-Nature-Serenity

* An incredible house with gorgeous 360° views* * 143 m² / 1539 ft² house size * Private Deck. Views of valley/Rionegro/Airport * Views of mountains * Privacy gate. Alarm. Parking for 5+ Cars * Fully stocked and equipped kitchen * 1 km / 0.6-mile dirt road to the house (any car will access) * There are two homes on the property, the main, larger house is Villa Serena where you will stay, the second home has a separate entrance and is not offered in Airbnb.

Top guest favourite
Farm stay in Cocorná
5 out of 5 average rating, 32 reviews

Bali-style cabin with forest and private river

Bali-style cabin with more than 2 hectares of private forest and river, hot Jacuzzi, wifi, spring climate, combining luxury and nature, deck next to the river, campfire, cinema-type video projector, shower with a view of nature, work and reading area, beautiful night lighting, kitchen and BBQ area, sun loungers and many other details designed to give you a unique experience and invite you to slow down and reconnect with yourself and nature

Top guest favourite
A covered jacuzzi is visible in the foreground, with bubbling water inviting relaxation. In the background, two hammocks are strung between trees, set against a lush green landscape and a wooden structure that complements the serene setting.
Farm stay in Retiro
4.99 out of 5 average rating, 150 reviews

"Authentic Antioquia Estate with All the Comforts"

Finca Sietecueros - Natural Refuge and Comfort in One Place Escape to Finca Sietecueros, a country house surrounded by forests and mountains. Relax in the jacuzzi, enjoy the hammocks under the trees, or share stories in the campfire area under a starry sky. Ideal for couples, families, and friends seeking peace, nature, and comfort in a unique setting. Book your stay and live an unforgettable experience in contact with nature!

Guest favourite
The cozy cabin is nestled in a lush green landscape, illuminated by warm outdoor lights. A wooden deck features comfortable seating, overlooking the serene surroundings. Large windows provide a glimpse of the interior, showcasing a warm and inviting space harmonized with nature.
Farm stay in Rionegro
4.95 out of 5 average rating, 300 reviews

Casa del Leñador | Secluded nature retreat

🪓 Retiro Cabin – Casa del Leñador is the house of our dreams. A small, cozy tiny home surrounded by nature. The perfect place to spend a few days as a couple, a family weekend, or work remotely in an environment without distractions. Wake up to birdsong at dawn and enjoy a campfire on the deck at dusk. At Retiro Cabin you will have total independence and an unparalleled view of the countryside in eastern Antioquia.

Popular amenities for Mesopotamia holiday rentals

  1. Airbnb
  2. Colombia
  3. Antioquia
  4. Mesopotamia