
Holiday rentals in Mesopotamia
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Top-rated holiday rentals in Mesopotamia
Guests agree: these stays are highly rated for location, cleanliness and more.

A wooden cabin in the El Retiro Antioquia forest
Imagine sleeping in a wooden cabin in a king-size bed with the lull of the river's sound. When you wake up you will feel like you are in a treehouse overlooking the snowflakes full of birds, going down to the garden with bare feet, having breakfast on the deck and seeing the horizon. During the day, walk, go to the river and the waterfall, get to the stone bathroom and the whirlpool, sit in the hammock, read, and at night light the fireplace (salamander), have a glass of wine at the kitchen counter with your partner, family, and friends.

Country house, excellent location, beautiful view!
Te invitamos a disfrutar de un hermoso espacio rodeado de naturaleza, con todas las comodidades para que puedas relajarte y descansar. Te sentirás como en casa. Lugar ideal para hacer teletrabajo (nómadas digitales) y estancias largas. A tan solo 10 minutos de La Ceja, 45 minutos del aeropuerto internacional y a una 1 hora de Medellín. Mascotas son bienvenidas. Adicionalmente ofrecemos clases de Yoga, terapias Ayurvedicas (Abhyanga/Swedana), clases de tenis. Lugar perfecto para turismo "slow"!

"Tierra Grata" House in Rionegro-Antioquia
This house has respected the environment in which it was created. With a forest around, you can see many kind of birds and squirrels, it is a space surrounded by nature, quiet, where you can rest. You have comfortable spaces. The cabin consists of 1 room with a double bed. 1 large bathroom, dining room and a teak deck. Totally equiped. From here, you can go visit Guatapé and Peñol stone (1 hour), the ceramics of Carmen de Viboral (45min), the Arvi park in Santa Elena (45 min) and Llanogrande.

Sweet Helen Llanogarden
Sweet Helen Llanogarden situado en el Tablazo-Llanogrande, a tan solo 10 minutos del aeropuerto internacional José Maria Córdova de Rionegro Antioquia, cerca a restaurantes, centros de eventos y malls, en el cual ofrecemos servicios de alojamiento para familias, amigos, parejas y viajes de negocios. En Sweet Helen Llanogarden encontrarás el espacio para pasar una estancia segura, tranquila y divertida, esta vez, rodeada de naturaleza y confort en la zona más exclusiva del oriente antioqueño.

luxury cabin with sauna, jacuzzy and private river
Enjoy the beautiful nature and tranquility of this luxurious accommodation with a sauna, jacuzzi, and private river terrace. Just 75 minutes from Medellín, this beautiful cabin is easily accessible by any car or motorcycle. The spectacular surroundings of Cocorná have much to offer, including paragliding, rafting, quad biking, and hiking trails along beautiful rivers. We are happy to assist you with transport or activities. We offer private transport from the airport! Includes breakfast!

luxury cabin in a native forest
Escape to Selvva Suites a luxury home nestled within a native forest just 50 mins from Medellín ,offering an exclusive experience. Located on the Llanogrande–La Ceja road. King-size bed, jacuzzi, fully equipped kitchen, bathroom with hot water, Wi-Fi, 65” Smart TV, and a surround sound system. Private parking with easy access for all types of vehicles. ⚠️ ✈️ The property is located in an area with air traffic; aircraft noise may be noticeable. 🐾 Pet-friendly (house rules apply)

Espi Ritual
Step into tranquility and reconnect with nature in this serene Llano Grando cabin. Soak up the patio sun, immerse yourself in the beautiful garden, or spot countless bird species on the sun-deck overlooking the pond. This cabin is equipped with WiFi, a full kitchen, an asador, and a private entrance. The perfect location for a peaceful solo trip, charming romantic getaway, or unique family adventure. 15 minutes from charming San Antonia and near restaurants and shopping

Nature & View | Cabin with a View
Nature & View just 8 min from JMC Airport Ideal for couples or travelers in transit. Our cabin offers a view of the valley, a quiet atmosphere, self check-in, an equipped kitchen, fast wifi, and all the comforts to relax. For your convenience, there are restaurants with home delivery and inside the accommodation you can buy cold drinks and snacks when you need them. 🚘 Trusted Uber driver Relax, order your favorite food and enjoy the view. Book your date!

☼♥Villa Serena ♥☼ 360° Views-Nature-Serenity
* An incredible house with gorgeous 360° views* * 143 m² / 1539 ft² house size * Private Deck. Views of valley/Rionegro/Airport * Views of mountains * Privacy gate. Alarm. Parking for 5+ Cars * Fully stocked and equipped kitchen * 1 km / 0.6-mile dirt road to the house (any car will access) * There are two homes on the property, the main, larger house is Villa Serena where you will stay, the second home has a separate entrance and is not offered in Airbnb.

Bali-style cabin with forest and private river
Bali-style cabin with more than 2 hectares of private forest and river, hot Jacuzzi, wifi, spring climate, combining luxury and nature, deck next to the river, campfire, cinema-type video projector, shower with a view of nature, work and reading area, beautiful night lighting, kitchen and BBQ area, sun loungers and many other details designed to give you a unique experience and invite you to slow down and reconnect with yourself and nature

"Authentic Antioquia Estate with All the Comforts"
Finca Sietecueros - Natural Refuge and Comfort in One Place Escape to Finca Sietecueros, a country house surrounded by forests and mountains. Relax in the jacuzzi, enjoy the hammocks under the trees, or share stories in the campfire area under a starry sky. Ideal for couples, families, and friends seeking peace, nature, and comfort in a unique setting. Book your stay and live an unforgettable experience in contact with nature!

Casa del Leñador | Secluded nature retreat
🪓 Retiro Cabin – Casa del Leñador is the house of our dreams. A small, cozy tiny home surrounded by nature. The perfect place to spend a few days as a couple, a family weekend, or work remotely in an environment without distractions. Wake up to birdsong at dawn and enjoy a campfire on the deck at dusk. At Retiro Cabin you will have total independence and an unparalleled view of the countryside in eastern Antioquia.
Popular amenities for Mesopotamia holiday rentals
Other great holiday rentals in Mesopotamia

Ubicación privilegiada en medio de la naturaleza

La Alpina, with a unique view

Romantic Tiny House · Private Jacuzzi · 8 min JMC

Breathtaking 5 Bedroom 6 Bath Private Jacuzzi Home

Casa Flores: Luxury Retreat Near Rionegro

Cozy Apartment La Union. (Ant)

El Encanto, a charming farm house

“Modern and comfortable loft in an excellent downtown area”
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- Lleras Park
- Atanasio Girardot Stadium
- Parque El Poblado
- Energy Living
- Parque Explora
- Plaza central de Guatapé
- Parque de los Pies Descalzos
- Viva Laureles
- Parque de Belén
- Plaza Mayor
- Plaza Botero
- Los Molinos Shopping Center
- Oviedo
- Unicentro Medellín
- Ciudad Del Río
- Museo de Antioquia
- Parque de Bostón
- San Diego Mall
- Parque Arvi
- Parque San Antonio de Pereira
- Comuna 13
- Museo Pablo Escobar
- Prado Centro
- El Tesoro Parque Comercial




