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Holiday rentals in Mesopotamia

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Mesopotamia

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
An aerial view of a modern house surrounded by tropical landscaping. Soft lights illuminate pathways leading to the entrance, while tall palm trees and diverse foliage create a serene atmosphere at night.
Cabin in Peñol
4.9 out of 5 average rating, 103 reviews

Cabin with jacuzzi and view of the reservoir, 8 people

Take it easy at this unique and tranquil getaway. This house in a subdivision with 3 spacious rooms, a Jacuzzi, a barbecue, access to the dam, and a stunning view of the Peñol stone ★"My wife explored the options and feels that your beautiful villa is her favorite in El Peñol." - Marcela, September 15 Exclusive condominium with few houses which will provide security during your stay, large terrace for your meetings and enjoyment with family or friends. Very safe and comfortable place Newly furnished☞ house.

Top guest favourite
A modern house is displayed with expansive glass walls, revealing a generous patio area. A private jacuzzi is surrounded by seating arrangements and tropical plants. The second-floor terrace features outdoor dining furniture, enhancing the view of the surrounding landscape.
Cottage in El Peñol
4.98 out of 5 average rating, 111 reviews

Casa*A/C*Jacuzzi/Wifi*Familia*represa/guatape

Disfruta una experiencia única en esta casa moderna con vista panorámica a la represa de Guatapé. Para familias y grupos de amigos que buscan descanso, confort, con diseño moderno, amplias terrazas y una vista impresionante sobre la represa. ✔Habitaciones del segundo pisco con A/C ✔ Acceso directo a la represa ✔ Jacuzzi privado ✔ Espacios amplios y luminosos ✔ Terraza de BBQ ✔ WiFi ✔ Parqueadero privado Vive momentos inolvidables rodeado de confort y tranquilidad, con los atractivos de Guatape.

Guest favourite
The wooden chalet is positioned in proximity to the large rock formation, featuring expansive glass windows that reflect the surrounding nature. A deck with outdoor seating enhances the connection to the landscape, while lush greenery frames the vibrant exterior.
Cabin in Guatapé
4.84 out of 5 average rating, 140 reviews

300m from Gran Piedra | King Size Beds | SmartTV

Wake up to an amazing view of the Piedra de Guatape and relax with direct access to the dam. We are located just 300 meters from the access to La Piedra and 5 minutes from the colorful town of Guatapé. The cabin is 50 meters from the main road, surrounded by nature but close to everything: restaurants, shops and options to explore. Ideal for families, couples, or small groups looking for tranquility, comfort, and an authentic connection with this magical place. We're waiting for you!

Guest favourite
Aerial view of three triangular-roofed cabins surrounded by lush greenery. A wooden deck features a private jacuzzi, while modern seating is arranged thoughtfully outdoors. The structure's glass doors allow for natural light, enhancing the serene ambiance created by the surrounding trees.
Tiny home in El Peñol
4.9 out of 5 average rating, 251 reviews

Lux cabin+ jacuzzi, kayak & lake view • Breakfast

🥘 Room service with local cuisine made from fresh ingredients grown in our garden and prepared on the spot 🍳 Breakfast included 🌐 High-speed fiber WiFi to stay connected 🛁 Private jacuzzi with stunning lake view 🔥 Gas fireplace for cozy nights 🚣‍♀️ Kayak and paddle board included to explore the lake 🐦 Birdwatching right from your terrace 📍 Located across the lake from one of the region’s most iconic estates, only 15 minutes from La Piedra del Peñol and 18 minutes from Guatapé.

Top guest favourite
A modern cabin is positioned on a hillside, surrounded by lush greenery and offering panoramic views of the surrounding landscape, including a prominent rock formation and a serene body of water in the foreground.
Tiny home in Guatape
4.98 out of 5 average rating, 642 reviews

Foresta: Modern cabin overlooking the Rock

FORESTA is a modern cabin created with love for you to have an unforgettable stay in the middle of nature, with total comfort. Enjoy the privileged views from the deck, chill out in the jacuzzi, watch the dozens of birds that visit us, or have a chat by the fireplace in the living room. FORESTA is a great launchpad to explore Guatape, climb the Rock and do kayaking, jet-skiing, wakeboarding, sailing, paraglading, horseback riding, hiking, helicopter tours or ATV rides. You choose!

Top guest favourite
An outdoor seating area features two woven armchairs and a small table, overlooking a stunning natural landscape with distant hills and sparkling lake waters. A wooden hot tub is positioned nearby, with safety glass panels enhancing the unobstructed views of the surrounding scenery.
Flat in El Peñol
4.99 out of 5 average rating, 107 reviews

Welcome to Ecolodge Paradise at Montecielo

Escape to tranquility in this serene mountain hideaway overlooking the sparkling waters of one of Colombia's most beautiful lakes. Nestled in the lush hills of Guatapé, our cozy retreat offers breathtaking panoramic views, fresh mountain air, and the perfect setting to unwind and recharge. Wake up to birdsong and misty sunrises, sip your morning coffee on the terrace, and spend your days exploring the vibrant town of Guatapé or simply relaxing in the peaceful embrace of nature.

Top guest favourite
A charming chalet is depicted beside a serene natural lake, framed by lush greenery and vibrant aquatic plants. The structure features rustic wooden details, large windows, and an expansive deck, inviting outdoor relaxation and enjoyment of the tranquil surroundings.
Cabin in Santa Elena
4.99 out of 5 average rating, 181 reviews

Chalet del Lago | Private Jacuzzi + Nature

🌿 Chalet del Lago – Santa Elena Escápate a un refugio natural con lago privado, amplios ventanales y un entorno lleno de paz. Con un muy completo equipamiento y distribución.A solo 10 minutos del parque principal, disfruta del canto de las aves, el sonido del agua y el clima fresco del campo antioqueño. Ideal para parejas, familias o una escapada de descanso. Naturaleza, tranquilidad y momentos inolvidables en un solo lugar. 💛✨ ✅ Somos pet friendly🐶🐈

Guest favourite
A serene lakeside terrace is visible, featuring a small round table and two chairs. Stone flooring complements the surrounding natural landscape, while trees and hills are reflected in the calm water, creating a peaceful setting for relaxation.
Cottage in Guatapé
4.84 out of 5 average rating, 760 reviews

Cottage - Private cabin - Guatapé, Jacuzzi, Kayak

Enjoy your rest in our charming cabin facing the lake. With breathtaking views, a private jacuzzi for relaxation, a spacious outdoor terrace, and space for nighttime bonfires, our retreat is the perfect place to disconnect and reconnect with nature. Additionally, you'll have access to exciting water activities such as kayaking and boat rides. Immerse yourself in the natural beauty of the region and let the magic of Lake Guatapé embrace you.

Top guest favourite
Cabin in Rionegro
4.98 out of 5 average rating, 107 reviews

Nature & View | Cabin with Jacuzzi and Nature

Enjoy an unforgettable experience in our private cabin, located just 8 minutes from José María Córdova International Airport. Enjoy a panoramic view of the city and relax in your private Jacuzzi. The cabin is equipped with a full kitchen, fast wifi, workspace and self check-in. You will find several nearby restaurants with home delivery, and inside the accommodation we have drinks and snacks to buy. 🚘 Trusted Uber driver

Guest favourite
Cabin in El Peñol
4.95 out of 5 average rating, 143 reviews

Sun Palm Cabin: Nature and Comfort in El Peñol!

Discover an exceptional retreat surrounded by nature, where every detail is designed to offer you an unforgettable experience. This cabin combines elegance and comfort. Relax in your private jacuzzi while enjoying breathtaking panoramic views in a serene environment. Perfect for a romantic getaway or rejuvenating vacation, you will find the ideal harmony between privacy and natural beauty. Your perfect escape awaits!

Guest favourite
Farm stay in Rionegro
4.95 out of 5 average rating, 301 reviews

Lumberjack's House | Secluded nature retreat

🪓 Retiro Cabin – Casa del Leñador is the house of our dreams. A small, cozy tiny home surrounded by nature. The perfect place to spend a few days as a couple, a family weekend, or work remotely in an environment without distractions. Wake up to birdsong at dawn and enjoy a campfire on the deck at dusk. At Retiro Cabin you will have total independence and an unparalleled view of the countryside in eastern Antioquia.

Top guest favourite
A single-story house surrounded by lush greenery is showcased. The exterior features a welcoming porch with seating and a hammock. The structure boasts large windows for natural light, while landscaped bushes and trees frame the property, enhancing the serene rural setting.
Farm stay in El Carmen de Viboral
4.97 out of 5 average rating, 106 reviews

☼♥Villa Serena ♥☼ 360° Views-Nature-Serenity

* An incredible house with gorgeous 360° views* * Private Deck. Views of valley/Airport * Mountain views * Privacy gate. Alarm. Parking for 2 Cars * Fully stocked and equipped kitchen * 1 km / 0.6-mile dirt road to the house (any car will access) * There are two homes on the property, the main, larger house is Villa Serena where you will stay, the second home has a separate entrance and is not offered in Airbnb.

Popular amenities for Mesopotamia holiday rentals

  1. Airbnb
  2. Colombia
  3. Antioquia
  4. Mesopotamia