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Places to stay near Mission San Luis Obispo de Tolosa

Book unique holiday rentals, homes and more on Airbnb

Top-rated holiday rentals near Mission San Luis Obispo de Tolosa

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
Loft in San Luis Obispo
4.99 out of 5 average rating, 561 reviews

Stylish and Comfortable Lofted Townhouse, Downtown SLO

Our goal is make you THRILLED to be here. Sparkling clean, luxurious and cozy. All amenities have been thoughtfully provided, similar to a 5-star hotel...luxury linens, feather-topped bed, plush robes, a lovely garden-like patio on which to enjoy your coffee or an afternoon wine and cheese plate. And first-day breakfast items are included for you to enjoy at your leisure!..organic Eggs, local baked goods, coffee, espresso, juice, fruit and yogurt. Most importantly, the location is a Dream! Just a few blocks from the downtown cultural-hub. The Perfect Location to come experience the “SLO Life”! The Loft was professionally designed to make you feel pampered and pleased! You won’t want to leave!! Perfect for Romantic get-aways, a fun Girls-Trip, and business travelers alike. We love to travel, and we appreciate the FINE details that set a place apart from the rest. We have put that experience to use here. All amenities have been thoughtfully provided. Similar to a 5-star hotel, you will find wifi, smart TV, a quaint electric-fireplace in the bedroom, luxury linens, comfy bed, plush robes, a lovely garden-like patio on which to enjoy a nice breakfast or enjoy an afternoon wine and cheese plate. And breakfast items are included for you to enjoy at your leisure..local Eggs, Local baked goods, Coffee, Illy Espresso, Orange juice and Fresh fruit await your arrival. You will be in the epicenter of all SLO has to offer, but JUST far enough away from the bustling downtown area to not be bothered by the noise or the late night crowd. Hiking trails abound here and the iconic Pismo and Avila beaches are mere minutes away. Come pamper yourself at the Loft. Our reviews say it all!... ~Recent Guest Comments: "Fantastic location. Walking distance to all that is going on in downtown SLO. The decor was so nice and the loft was planned carefully to provide everything you could possibly need during your stay." -Pam "Thanks for everything! This was my favorite Airbnb stay to date and I want to thank you for your responsiveness and for allowing us to stay. Would love to stay again soon!" - Andrew "The cleanest Airbnb we've stayed in to date. We will be back." - John Guests will have exclusive access to the entire home. Your Reserved parking space is just steps from your front door. Laundry facilities are on site. You have a private garden-like patio on which to sip your morning coffee or enjoy an afternoon wine and cheese plate. We are available to answer any questions and offer suggestions from where to eat to what to do during your visit here in SLO county! If you need anything more, please ask. We aim to please! The loft is within walking distance of the coffee houses, eateries, and shops of the Old Town Historic District, Thursday Night Farmer's Market and the Historic Mission. There are many great parks in the area that offer wonderful walking/biking/hiking trails, and Cal Poly State University is a short drive away. A few minutes to the South of the Loft you will find yourself in the beautigul heart of Edna Valley wine country. Iconic Avila, Shell and Pismo Beaches are a mere 10 minutes away as well. Train | Plane | Car | Bus SLO Amtrak train station is just .4 miles from our condo. SLO County Regional Airport - 2.8 miles. Regional Bus service has easy access The heart of Downtown SLO is a 3 minute walk For transportation to or from the airport may we recommend Ride Uber at San Luis Obispo County Regional (SLO) Airport The space is cozy and perfectly suited for two.

Top guest favourite
A charming garden area is framed by brick pathways, with a wooden table and chairs positioned nearby. Lush greenery and various plants create a serene outdoor atmosphere, while a wooden gate provides privacy and access to the space. The ground appears damp, suggesting recent rain.
Guest house in San Luis Obispo
4.97 out of 5 average rating, 668 reviews

SLO Guesthouse - quiet - near downtown - #115545

Private studio with it's own entrance located in lovely SLO. Includes a queen size Murphy bed (people rave about the comfort of this bed), 3 piece bathroom, table & two chairs, desk, closet, TV, WiFi & kitchenette. Coffee, tea with fixings are provided. 4 blocks from the downtown cultural-hub, hip restaurants, Farmer's Market, the Historic Mission and more. The Edna Valley wine country is 5 minutes away and the Beach is 10 minutes away. The Perfect Location to come experience the "SLO Life"!

Top guest favourite
Home in San Luis Obispo
4.96 out of 5 average rating, 365 reviews

Adorable SLO Cottage

Available August 1st for a one year lease. $2,300/mo w/o utilities. Our charming cottage is located in a historic and dog-friendly neighborhood in San Luis Obispo. This private and standalone house has a modern living area of nearly 400 sq. ft. and a private gated yard, making it ideal for you, your loved ones, and your furry friends. With a private off-street parking spot, you'll have easy access to the cottage. This sanctuary is perfect for anyone seeking a private and convenient escape.

Top guest favourite
A light-filled studio is presented with a spacious bed, blue cabinetry, and a full kitchen that includes a microwave and stove. A small dining table with black chairs is positioned near the windows, providing a view of the room's warm wooden flooring.
Guest house in San Luis Obispo
4.97 out of 5 average rating, 612 reviews

Downtown Historic District Sunset Studio

Enjoy a hotel quality stay, professionally cleaned prior to each guest, located in the beautiful downtown historic district. Studio is equipped to provide you with everything you need for an enjoyable stay; including washer/dryer, AC/ Heat. From the deck enjoy magnificent sunset views framed by San Luis Mountain and Bishop's Peak while enjoying dining al fresco. We are 4 walkable blocks to downtown and a mile to Cal Poly. The beach is about a 10 min drive away. You can't beat the location!

Top guest favourite
A modern kitchen features vibrant blue cabinetry contrasting with light walls and natural accents. A sleek stove and stainless-steel appliances are present alongside a small wooden dining table and chair. Large windows allow ample natural light, complemented by greenery from potted plants.
Home in San Luis Obispo
5 out of 5 average rating, 219 reviews

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT

Step into history at this charming 2-bedroom railroad house in downtown SLO. Enjoy its preserved heritage, from the 11-foot tall ceilings to the spacious kitchen. Sleep luxuriously on Purple mattresses in both bedrooms. Unwind next to the fire pit in the backyard. It's a short 7 min. stroll to downtown & next to 5 restaurants including Sally Lou's coffee shop & the train station. Experience SLO's charm like never before with this perfect location home. Send us a message to plan your trip!

Top guest favourite
A historic two-story home is depicted, showcasing detailed architectural features such as a wide front porch with white railings and decorative columns. The exterior is painted in soft green hues, surrounded by landscaped gardens and trees, with a sign indicating its location in the Mill Street Historic District.
Place to stay in San Luis Obispo
4.98 out of 5 average rating, 571 reviews

Rooftop Patio Downtown Suite- 4-5 Guests

Historic 1887 home with modern interior. Entire upper floor suite (700 sq ft) with private entrance, galley kitchen, laundry, common space (recently updated w/ comfy seating for 4-see photos below!), bathroom and two bedrooms. This space was remodeled in 2019 and has a fully equipped kitchen and private rooftop deck with views of Cerro San Luis and Bishop Peak. Stroll out your door and find downtown SLO a couple blocks away. Cal Poly is located 1 mi away. Homestay Lic # 115822

Top guest favourite
A bright living area features a white sofa adorned with throw pillows and a cozy blanket. A round wooden coffee table sits at the center, surrounded by a jute area rug. Natural light floods in through large windows, framing views of lush greenery outside.
Guest house in San Luis Obispo
4.98 out of 5 average rating, 119 reviews

Near Cal Poly, Down Town & Mt Hikes; Easy Prking

When you arrive in sunny San Luis Obispo, you’ll be surrounded by beautiful mountains in a quiet neighborhood. You will be close to downtown and Cal Poly, and just 15 minutes to the beach. Enjoy wine tasting in gorgeous vineyards, hiking and biking stunning mountain trails, and savoring farm-to-table eateries or craft cocktail lounges. You can cook in our Art Deco kitchen with hand-painted floors and relax at the outdoor bar/patio. Enjoy life on the SLO Lane. You’ll love it!

Guest favourite
The exterior of the home is framed by vibrant red foliage, with a mix of trees and shrubs surrounding a well-maintained lawn. Large windows provide views into the interior, while a wooden deck extends outward, complementing the natural landscape.
Home in San Luis Obispo
4.86 out of 5 average rating, 134 reviews

Serenity On Serrano

Serenity on Serrano is a Frank Lloyd Wright-inspired peaceful haven set in one of SLO's most prestigious neighborhoods right on the edge of a creek. This midcentury modern home is just steps to hiking, the downtown, shopping, and restaurants. Be prepared for nature as it's common to be greeted by wild turkeys, birds, and more. Enjoy the tranquility of minimalist design. Note: There is $25 per night for each extra guest over 4. Permit # H-0408-2023

Top guest favourite
A bright living area features a comfortable sofa and two accent chairs, surrounded by natural light from large windows. A coffee table with a decorative centerpiece sits on a patterned rug, while a flat-screen television is mounted above the fireplace, enhancing the cozy atmosphere.
Home in San Luis Obispo
4.96 out of 5 average rating, 457 reviews

The Downtown House SLO with Private Parking

Charming 1920s bungalow in the heart of downtown San Luis Obispo! Walk to top restaurants, coffee shops, parks, and the famous Farmers Market. Perfect for SLO Marathon runners—just a mile from the starting line. Original details + modern upgrades, A/C, full kitchen, laundry, and parking. Ideal for guests who love vibrant, walkable neighborhoods. We’re locals and happy to share our favorite hikes, wineries, and spots to explore!

Top guest favourite
A dining area features a wooden table surrounded by four chairs, complemented by a decorative rug. Exposed beams and ductwork enhance the industrial style. Natural light fills the space through large glass walls, revealing the adjacent kitchen and bedroom area.
Home in San Luis Obispo
4.98 out of 5 average rating, 308 reviews

Mid Century Modern Loft Downtown SLO

This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.

Top guest favourite
Bungalow in San Luis Obispo
4.86 out of 5 average rating, 296 reviews

Boho Bungalow+walkable+stocked kitchen+BBQ+private

Charming 1920s Bungalow in SLO’s Historic Railroad District Nestled on the corner of two iconic streets in the heart of the Railroad District, this beautifully restored 1920s bungalow offers the perfect blend of vintage charm and modern comfort. Step inside and be greeted by abundant natural light, tasteful décor, and a cozy open studio layout designed for relaxation.

Top guest favourite
A contemporary home is highlighted with expansive glass doors, allowing views of the surrounding landscape. A wooden dining table is shown, adorned with a sunflower. The deck extends along the residence, featuring comfortable seating areas.
Home in San Luis Obispo
4.96 out of 5 average rating, 138 reviews

Sanctuary on Sunset Ridge ~ Panoramic Ocean Views

Enjoy extraordinary VIEWS, PEACE, and PRIVACY just 15 minutes from downtown and beaches. Within 10-15 minutes: Hiking, Biking, SUP, Kayaking, Surfing, Wine Tasting, Great Restaurants, etc., etc. We are good-dog friendly. 3-night minimum stay. We have 2 ensuite King bedrooms - the 2nd has a loft with a double bed. Check us out on Insta: @sanctuaryonsunsetridge

Popular amenities for holiday rentals near Mission San Luis Obispo de Tolosa