
Places to stay near Mission San Luis Obispo de Tolosa
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Top-rated holiday rentals near Mission San Luis Obispo de Tolosa
Guests agree: these stays are highly rated for location, cleanliness and more.

SLO Guesthouse - quiet - near downtown - #115545
Private studio with it's own entrance located in lovely SLO. Includes a queen size Murphy bed (people rave about the comfort of this bed), 3 piece bathroom, table & two chairs, desk, closet, TV, WiFi & kitchenette. Coffee, tea with fixings are provided. 4 blocks from the downtown cultural-hub, hip restaurants, Farmer's Market, the Historic Mission and more. The Edna Valley wine country is 5 minutes away and the Beach is 10 minutes away. The Perfect Location to come experience the "SLO Life"!

Modern Private Cottage+walkable+views+patio w/ BBQ
This adorable cottage is located 1 mile from downtown SLO and is equidistant to local wineries! Clean and tastefully decorated- equip with a full kitchen, comfortable sleeping accommodations and all the modern luxuries of home. This private studio is nestled on the backside of a beautifully landscaped property with a separate entrance and secluded patio area distanced from the main home offering you peace and serenity. Just a short stroll to Taste, SLO Co-Op, Del Monte's, Sally Loo's & many more

Eclectic apartment in the heart of downtown SLO.
This charming, newly updated, 1 BR apartment is part of an 1883 Folk Victorian in the heart of SLO's downtown historic district and was recently added to the California Master List of Historic Resources as 'The D.M. & Carrie Proper Meredith House'. This cozy apartment offers convenience, style, safety, and privacy - all while being just a two-minute walk to all your favorite bars, restaurants, cafes, movie theatres, and shops. Your hosts aim to provide you with an amazing 5-star experience!

Mountain View Studio - No Cleaning Fee!
Your home away from home is close to Cal Poly, hiking, art and culture, great views, restaurants, wineries, and several beaches. This spacious studio apartment has a super-comfy bed and is located in a quiet neighborhood with easy access to all things SLO. We use only natural, organic cleaning products, and all sheets and towels are of high-quality cotton. Kitchenette stocked with coffee, tea, etc. Smart TV. Licensed in the city of SLO ( #113984), so a required 13% lodging tax is included.

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT
Step into history at this charming 2-bedroom railroad house in downtown SLO. Enjoy its preserved heritage, from the 11-foot tall ceilings to the spacious kitchen. Sleep luxuriously on Purple mattresses in both bedrooms. Unwind next to the fire pit in the backyard. It's a short 7 min. stroll to downtown & next to 5 restaurants including Sally Lou's coffee shop & the train station. Experience SLO's charm like never before with this perfect location home. Send us a message to plan your trip!

Rooftop Patio Downtown Suite- 4-5 Guests
Historic 1887 home with modern interior. Entire upper floor suite (700 sq ft) with private entrance, galley kitchen, laundry, common space (recently updated w/ comfy seating for 4-see photos below!), bathroom and two bedrooms. This space was remodeled in 2019 and has a fully equipped kitchen and private rooftop deck with views of Cerro San Luis and Bishop Peak. Stroll out your door and find downtown SLO a couple blocks away. Cal Poly is located 1 mi away. Homestay Lic # 115822

Cottage in SLO / Historic Downtown District
“Cottage in SLO” is located in the historic district of San Luis Obispo with its century old homes and buildings. Enjoy the three block walk to downtown with all its amenities: Restaurants to please every pallet, from BBQ to gourmet. Coffee shops, theaters, galleries, and the world famous Farmers Market event every Thursday night. Bike paths are on the same street that will take you anywhere in SLO and beyond. . (Bikes provided) Perfect for two. Homestay permit # -0606-2019

Mid-Century Design Close to Downtown & Cal Poly
Mid-Century-Design Homestay's private addition offers a tranquil space to explore San Luis Obispo and Central Coast. We thoroughly clean and sanitize plus HEPA air purifier - 24/7. Two separate bedrooms. Fine Art and white walls with large windows that lead out to a private shaded deck w/firepit table for 6. License #113141. It has heat/AC, kitchenette, Pvt. bathroom off of the main bedroom, washer/dryer, Pvt. entrance, free parking, with or without a friendly Lab.

Serenity On Serrano
Serenity on Serrano is a Frank Lloyd Wright-inspired peaceful haven set in one of SLO's most prestigious neighborhoods right on the edge of a creek. This midcentury modern home is just steps to hiking, the downtown, shopping, and restaurants. Be prepared for nature as it's common to be greeted by wild turkeys, birds, and more. Enjoy the tranquility of minimalist design. Note: There is $25 per night for each extra guest over 4. Permit # H-0408-2023

The Downtown House SLO with Private Parking
Charming 1920s bungalow in the heart of downtown San Luis Obispo! Walk to top restaurants, coffee shops, parks, and the famous Farmers Market. Perfect for SLO Marathon runners—just a mile from the starting line. Original details + modern upgrades, A/C, full kitchen, laundry, and parking. Ideal for guests who love vibrant, walkable neighborhoods. We’re locals and happy to share our favorite hikes, wineries, and spots to explore!

Mid Century Modern Loft Downtown SLO
This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.

Close to Downtown SLO
Enjoy this clean 420 sqft space in a great SLO location. Close distance to town, restaurants, bike paths & hiking. Private entrance. Open concept style, queen bed and twin sofa option. Large walk-closet with extra bedding and towels. Fully equipped kitchen: refrigerator, oven, microwave, dishwasher, reverse osmosis for drinking water & garbage disposal. Beautifully done bathroom with large shower & vanity
Popular amenities for holiday rentals near Mission San Luis Obispo de Tolosa
Other top sights near Mission San Luis Obispo de Tolosa
Apartment rentals with wifi

Avila Good Life - A luxury 2 Bdrm condo 3 houses f

Luxury Condo in Downtown Pismo Beach, Rooftop Spa!

Downtown Pismo Cottage - Beach, Patio, Parking

Whale Hello! Avila Oceano Pismo

Sand Dollar Hideaway-Luxury Condo, Prime Location!

The Hideaway in SLO

Grand Getaway: Ocean Views and Open Living Space!

Pismo Oceanfront, Private Garage, Pet/ADA Friendly
Family-friendly house rentals

NEW Cozy Private House -Near Cal Poly and DT SLO

Chelsea’s on Victoria

Great little beach house. County License# 6012116

Near the Bay .8 mi Private Studio

Cozy Studio Close to Downtown SLO

Bungalow by the Bay

Spacious Slo Studio: AirBnB Dream

Cozy, Clean and Close to downtown SLO!
Apartment rentals with air conditioning

Very Spacious Edna Valley Luxury Apartment

Spacious 2BD w/rural views

URGH Casita (Small House in a barn)

Boho Bungalow with Ocean View in Grover Beach

Downtown View Suite at Pismo Beach Club

Pet Friendly Bright & Airy SLO Apartment

Charming Cambria studio

Quiet garden studio with sunny deck
Other great holiday rentals near Mission San Luis Obispo de Tolosa

Near Cal Poly, Down Town & Mt Hikes; Easy Prking

Downtown Bungalow

The Barn at Old Morro

Downtown Historic District Sunset Studio

☆Gorgeous hideout☆ Scenic views | Tranquil terrace

Mountaintop Retreat- Guest House

Peaceful Cottage in an Olive Grove

Guest suite in San Luis Obispo
Destinations to explore
- Cayucos Beach
- Moonstone Beach
- Moonstone Beach
- Hearst San Simeon State Park
- Montaña de Oro State Park
- Natalie's Cove
- B & E Vineyard & Winery
- Morro Strand State Beach
- Cayucos State Beach
- Dairy Creek Golf Course
- Seal Beach
- Morro Bay Golf Course
- Pirates Cove Beach
- Morro Rock Beach
- Sand Dollars
- Olde Port Beach
- Spooner's Cove
- Point Sal State Beach
- Bovino Vineyards
- Bianchi Winery
- Baywood Park Beach
- Allegretto Wines
- Pismo State Beach
- Au Bon Climat




