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Places to stay near Plaza de Santo Domingo

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Top-rated holiday rentals near Plaza de Santo Domingo

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Serviced apartment in Centro
4.88 out of 5 average rating, 177 reviews

Santos de Piedra Apartment in the walled City

Luxurious PRIVATE colonial apartment, with the best location, in front of the Cathedral of Santa Catalina. First level: living-dining room with an open-plan kitchen laundry area and social bathroom. Bedroom with private bathroom and king-sized bed, also patio with a pool for private use. Second floor: two bedrooms with private bathrooms, one with Queen bed and the other with twin beds Free housekeeper / breakfast and lunch negotiable with Sonia / free coffee / free water Rossana and Martin

Guest favourite
The image features a view of orange and yellow buildings topped with terracotta roofs. A prominent cathedral spire is visible in the background against a clear blue sky. Decorative balconies and lush greenery add charm to the setting.
Flat in Centro
4.82 out of 5 average rating, 257 reviews

In the heart of Cartagena

No tricks! Our cover picture is the actual view from the living-room! Our lovely flat is located in the walled city, next to the vibrant Santo Domingo square. Unique feature: our living has a small balcony over the beautiful Gastelbondo street (not an interior patio, or a wall), but keeps calm at night. 2 bedrooms, 2 bathrooms, a nice living with sofa and a hammock to take a nap : the perfect place for your stay in Cartagena! Our bonus: our building’s rooftop for your sunsets…

Top guest favourite
A serene pool area is surrounded by tropical greenery, featuring a circular plant island at the center. Plush seating is available beside the pool, with draped curtains providing a sense of privacy. Soft lighting highlights the textured walls, creating a calming ambiance.
Home in Centro
4.91 out of 5 average rating, 232 reviews

Private Heated Pool+Jacuzzi | Colonial Walled City

Step into one of Cartagena's most iconic streets — Calle de las Damas — and into a beautifully appointed colonial home that blends centuries of history with every modern comfort. Located in the heart of the Walled City, Casa Calle de las Damas is the perfect base for experiencing the real magic of Cartagena. Whether you're traveling with family or a group of friends, this spacious 2-bedroom, 2 1/2-bathroom home offers an elegant and relaxed atmosphere you'll never want to leave.

Luxe
A spacious terrace area is shown, featuring comfortable lounge chairs and a shaded umbrella. Lush greenery surrounds the space, creating a relaxed atmosphere. Light-colored furniture is complemented by woven details, and a refreshing pool is visible in the background, enhancing the outdoor experience.
Villa in Centro
4.93 out of 5 average rating, 124 reviews

Casa O Cochera Luxury Boutique House

Welcome to Casa O Cochera! Immerse yourself in luxury at this new 4-story haven in San Diego's enchanting Walled City. Designed by the renowned architect Vladimir Caballero, our house accommodates 8 guests with utmost comfort. Enjoy complimentary delicious breakfast, airport transfer and attentive housekeepers. Elevate your stay with optional catering, entertainment, and exciting tours. Your unforgettable getaway awaits! Book now and create beautiful memories at Casa O Cochera.

Top guest favourite
A spacious loft suite is presented with an open layout, featuring a modern spiral staircase leading to a lofted sleeping area. Soft neutral tones and green plant decor enhance the environment. Seating arrangements include a large, curvy couch and a wooden table, creating a comfortable gathering space.
Flat in Centro
5.0 out of 5 average rating, 104 reviews

Luxury Suite/Loft Apt/CityCenter

1 BR Loft Suite in the heart of Cartagena inspired by some of the finest 5 star Hotels in the world. Located inside the walls of the old city, within walking distance to shops, entertainment, restaurants, nightclubs & bars. Enjoy staying in this Unesco Heritage town full of history & excitement. Fully equipped kitchen with Washer/Dryer, Queen Sized Bed, TV, Netflix and 400MbWi-Fi. Our modern beach vibe apartment is perfect for a couple to enjoy and relax Insta @pombocartagena

Top guest favourite
A well-appointed bedroom features a spacious bed adorned with colorful linens. Ambient lighting from side tables enhances the room's warmth. A ceiling fan is present above, and a cozy seating area with a light-colored armchair complements the dark checkered floor. Traditional wooden doors add charm.
Flat in Centro
4.91 out of 5 average rating, 273 reviews

Casa San Pedro

The apartment is on a very special street next to the San Pedro Claver church, full of restaurants. It has easy access to places of interest such as Plaza de la Aduana, the cathedral, and others. In this place you will have an experience with colonial Cartagena with all the amenities you want. It has WiFi, a 60-inch TV, a bathroom, hot water, a fully-equipped kitchen, A/C, a balcony, and soundproof doors. Ready to have an excellent stay

Guest favourite
Flat in Centro
4.96 out of 5 average rating, 457 reviews

Boutique Stay in Historic Center + Local Concierge

Stay in the heart of Cartagena with a curated local experience. Your stay includes access to a private concierge who can help design your trip—from hidden restaurants to unforgettable moments. Recently redecorated 2-bedroom apartment with full A/C, a bright and relaxed atmosphere, Smart TV, PS4, dining for six, and 24/7 security. Steps from vibrant plazas, cafés, and historic landmarks—your Caribbean retreat awaits.

Guest favourite
A rooftop terrace is presented with a spiral staircase, leading to additional levels. A private pool is featured along one side, complemented by lounge chairs and a sofa. Soft lighting highlights the terracotta walls, enhancing the evening ambiance.
Home in Centro
4.88 out of 5 average rating, 156 reviews

casa encantada

Walled city. Magnificent four-story house exclusively for guests. With a small private pool in the Rooftop. Located in the historic center of the walled city of Cartagena near the Baruco restaurant, bars, galleries, house of the inquisition, Plaza Botero, clock tower, shops, pharmacies, art with a spectacular viewpoint. With air conditioning in the living room, kitchen and bedrooms.

Guest favourite
A spacious living area is characterized by high ceilings with wooden beams and a large chandelier. Comfortable seating is provided with two armchairs and a sofa. A wooden table with an artistic design sits in the center, complemented by a bar area in the background.
Flat in Centro
4.88 out of 5 average rating, 670 reviews

School House

A charming two bedroom, 2.5 bathroom apartment in the center of the Old Town, a few steps from Cartagena’s coveted museums, restaurants, galleries and shops. The property includes a large living room, dining area, kitchen, and balcony overlooking picturesque colonial streets. Housekeeping is included (every other day) to ensure a stress-free stay (except Sundays & holidays).

Guest favourite
Flat in Centro
4.88 out of 5 average rating, 217 reviews

2B in Heart of Old Walled City. Views & Pool.

Captivating 2 bed and 2.5 bath apt in the heart of the Walled City. The property is an apt on the 2nd floor of La Encantada, a colonial home with 100+ yr history. Highly rated restaurants, shops and museums steps away. Great views with two terraces (--private--) and a small pool (--shared--). Max 4 guests. The apt does NOT have hot water. Flexible check in time.

Guest favourite
A rooftop terrace features a relaxing Jacuzzi surrounded by lounge chairs, with vibrant greenery nearby. The scene is enhanced by a stunning sunset and a historic tower in the background, creating a serene atmosphere for relaxation.
Flat in Centro
4.98 out of 5 average rating, 225 reviews

Exclusive Apt in Walled City | Rooftop Jacuzzi!

Welcome to this EXCLUSIVE apartment right in the heart of the Walled city. Just steps away from restaurants, bars, coffee shops and some of the most iconic plazas, churches and museums. Perfect for weekend getaways, business trips, working nomads or cozy home base while exploring everything Cartagena has to offer! NO UNREGISTERED VISITORS ALLOWED!

Guest favourite
A spacious living area is presented, featuring a comfortable sofa adorned with patterned cushions. A wooden coffee table sits in front, with a decorative plant nearby. The loft's upper level is visible, offering a glimpse of the bedroom, while soft lighting enhances the inviting ambiance.
Loft in Centro
4.84 out of 5 average rating, 205 reviews

Classic loft in the heart of the Walled City

Enjoy an unforgettable experience within Cartagena's walls. This loft is located in one of the city's most iconic buildings and historical heritage, within walking distance of the best restaurants, cafes, tourist sites, recreation and entertainment. Come and learn a little about our history and rest in a clean place with the comforts of home.

Popular amenities for holiday rentals near Plaza de Santo Domingo