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Places to stay near Plaza de Santo Domingo

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Top-rated holiday rentals near Plaza de Santo Domingo

Guests agree: these stays are highly rated for location, cleanliness and more.

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A vibrant colonial building features a warm yellow façade adorned with lush green vines. The second floor showcases wooden balconies with intricate details, adding charm to the historic architecture. Pedestrians are seen enjoying the lively atmosphere of the street.
Place to stay in Centro
4.93 out of 5 average rating, 435 reviews

Colonial Jewel with Balcony in Old City’s Heart

Experience a Stunning 17th-century Grand Colonial Mansion in Cartagena on Beautiful Santo Domingo Street, the Heart of the Historic City. A dream Loft just for you, with a Balcony, to enjoy the Caribbean vibe, your morning coffee, or a sunset rum. Steps from the main Plazas, Churches, Museums, and The Best Restaurants and Cafés. Exquisitely furnished, living-dining, kitchen, marble floors and bath, hammock, queen bed, premium 100% cotton linens & towels. A Magical, UNFORGETTABLE experience! ✨

Top guest favourite
A modern living space features a stylish dining area with a large table surrounded by light-colored chairs. Above, a well-lit kitchen is visible, complemented by a cozy seating area with armchairs. Exposed stone walls add texture, while pendant lights provide a warm glow.
Apartment in Centro
4.96 out of 5 average rating, 473 reviews

Luxury Duplex · Best Location Historic Center

Exclusive duplex apartment located on the second floor of a majestic republican-era building, a true architectural gem from the early 20th century. Enjoy a privileged view of iconic Calle del Cuartel and immerse yourself in the charm of the Historic Center. Fully equipped with air conditioning throughout, Smart TVs in bedrooms and living area, high-speed WiFi, a complete kitchen, linens, towels, and hot water. Prime location steps from top restaurants, cafés, and Cartagena nightlife.

Top guest favourite
A serene pool area is surrounded by tropical greenery, featuring a circular plant island at the center. Plush seating is available beside the pool, with draped curtains providing a sense of privacy. Soft lighting highlights the textured walls, creating a calming ambiance.
Home in Centro
4.91 out of 5 average rating, 232 reviews

Private Heated Pool+Jacuzzi | Colonial Walled City

Step into one of Cartagena's most iconic streets — Calle de las Damas — and into a beautifully appointed colonial home that blends centuries of history with every modern comfort. Located in the heart of the Walled City, Casa Calle de las Damas is the perfect base for experiencing the real magic of Cartagena. Whether you're traveling with family or a group of friends, this spacious 2-bedroom, 2 1/2-bathroom home offers an elegant and relaxed atmosphere you'll never want to leave.

Top guest favourite
A rooftop terrace features a relaxing hot tub surrounded by lush greenery. Comfortable seating areas include wicker chairs and a wooden table, with stunning views of the city skyline and distant hills under a clear blue sky.
Home in Getsemany
4.99 out of 5 average rating, 128 reviews

Casa O Getsemani Luxury Boutique House

Welcome to Casa O Getsemani! Immerse yourself in luxury at this new 4-story haven in in the coolest neighborhoods.Designed by the renowned architect Vladimir Caballero, our house accommodates 6 guests with utmost comfort. Enjoy complimentary delicious breakfast, airport transfer and attentive housekeepers. Elevate your stay with optional catering, entertainment, and exciting tours. Your unforgettable getaway awaits! Book now and create beautiful memories at Casa O Getsemani.

Top guest favourite
A spacious loft suite is presented with an open layout, featuring a modern spiral staircase leading to a lofted sleeping area. Soft neutral tones and green plant decor enhance the environment. Seating arrangements include a large, curvy couch and a wooden table, creating a comfortable gathering space.
Flat in Centro
5.0 out of 5 average rating, 106 reviews

Luxury Suite/Loft Apt/CityCenter

1 BR Loft Suite in the heart of Cartagena inspired by some of the finest 5 star Hotels in the world. Located inside the walls of the old city, within walking distance to shops, entertainment, restaurants, nightclubs & bars. Enjoy staying in this Unesco Heritage town full of history & excitement. Fully equipped kitchen with Washer/Dryer, Queen Sized Bed, TV, Netflix and 400MbWi-Fi. Our modern beach vibe apartment is perfect for a couple to enjoy and relax Insta @pombocartagena

Top guest favourite
A serene private space features a jacuzzi surrounded by textured stone walls and warm wooden accents. A comfortable seating area with plush cushions invites relaxation, while natural light enhances the tranquil atmosphere.
Home in Centro
4.85 out of 5 average rating, 206 reviews

Casa Rosa - Private Pool and Jacuzzi

Beautiful new home in Calle de las Carretas, half block from Clock Tower (Tower Clock). The house is in the first floor and has 2 rooms, each room has his own private bathroom. There is a jacuzzi/pool in the house. Casa Carretas has 2 rooms, with a private bathroom each one. The house is fully equiped, the kitchen has everything you need for your stay and daily cleaning is included in the price, amenities are provided with your reservation.

Guest favourite
Flat in Centro
4.96 out of 5 average rating, 457 reviews

Boutique Stay in Historic Center + Local Concierge

Stay in the heart of Cartagena with a curated local experience. Your stay includes access to a private concierge who can help design your trip—from hidden restaurants to unforgettable moments. Recently redecorated 2-bedroom apartment with full A/C, a bright and relaxed atmosphere, Smart TV, PS4, dining for six, and 24/7 security. Steps from vibrant plazas, cafés, and historic landmarks—your Caribbean retreat awaits.

Guest favourite
A rooftop terrace is presented with a spiral staircase, leading to additional levels. A private pool is featured along one side, complemented by lounge chairs and a sofa. Soft lighting highlights the terracotta walls, enhancing the evening ambiance.
Home in Centro
4.88 out of 5 average rating, 156 reviews

casa encantada

Walled city. Magnificent four-story house exclusively for guests. With a small private pool in the Rooftop. Located in the historic center of the walled city of Cartagena near the Baruco restaurant, bars, galleries, house of the inquisition, Plaza Botero, clock tower, shops, pharmacies, art with a spectacular viewpoint. With air conditioning in the living room, kitchen and bedrooms.

Guest favourite
A spacious living area is characterized by high ceilings with wooden beams and a large chandelier. Comfortable seating is provided with two armchairs and a sofa. A wooden table with an artistic design sits in the center, complemented by a bar area in the background.
Flat in Centro
4.88 out of 5 average rating, 672 reviews

School House

A charming two bedroom, 2.5 bathroom apartment in the center of the Old Town, a few steps from Cartagena’s coveted museums, restaurants, galleries and shops. The property includes a large living room, dining area, kitchen, and balcony overlooking picturesque colonial streets. Housekeeping is included (every other day) to ensure a stress-free stay (except Sundays & holidays).

Guest favourite
Flat in Centro
4.89 out of 5 average rating, 218 reviews

2B in Heart of Old Walled City. Views & Pool.

Captivating 2 bed and 2.5 bath apt in the heart of the Walled City. The property is an apt on the 2nd floor of La Encantada, a colonial home with 100+ yr history. Highly rated restaurants, shops and museums steps away. Great views with two terraces (--private--) and a small pool (--shared--). Max 4 guests. The apt does NOT have hot water. Flexible check in time.

Guest favourite
A rooftop terrace features a relaxing Jacuzzi surrounded by lounge chairs, with vibrant greenery nearby. The scene is enhanced by a stunning sunset and a historic tower in the background, creating a serene atmosphere for relaxation.
Flat in Centro
4.98 out of 5 average rating, 227 reviews

Exclusive Apt in Walled City | Rooftop Jacuzzi!

Welcome to this EXCLUSIVE apartment right in the heart of the Walled city. Just steps away from restaurants, bars, coffee shops and some of the most iconic plazas, churches and museums. Perfect for weekend getaways, business trips, working nomads or cozy home base while exploring everything Cartagena has to offer! NO UNREGISTERED VISITORS ALLOWED!

Guest favourite
A refreshing pool is situated on a terrace, surrounded by lush greenery. Two glasses sit on a wooden tray alongside neatly arranged towels. The background features an expansive ocean view and the skyline of a nearby city under a partly cloudy sky.
Villa in Centro
4.89 out of 5 average rating, 133 reviews

Historic oceanfront villa/private rooftop pool

A private oasis nestled on Cartagena’s iconic city walls. Casa de la Artillería blends timeless colonial charm with modern comfort, featuring a private rooftop pool, breathtaking Caribbean views and an unbeatable location just steps from the city’s finest restaurants, cafés and vibrant plazas.

Popular amenities for holiday rentals near Plaza de Santo Domingo