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Places to stay near Plaza de Santo Domingo

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Top-rated holiday rentals near Plaza de Santo Domingo

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Serviced apartment in Centro
4.88 out of 5 average rating, 177 reviews

Santos de Piedra Apartment in the walled City

Luxurious PRIVATE colonial apartment, with the best location, in front of the Cathedral of Santa Catalina. First level: living-dining room with an open-plan kitchen laundry area and social bathroom. Bedroom with private bathroom and king-sized bed, also patio with a pool for private use. Second floor: two bedrooms with private bathrooms, one with Queen bed and the other with twin beds Free housekeeper / breakfast and lunch negotiable with Sonia / free coffee / free water Rossana and Martin

Superhost
A vibrant colonial building features a warm yellow façade adorned with lush green vines. The second floor showcases wooden balconies with intricate details, adding charm to the historic architecture. Pedestrians are seen enjoying the lively atmosphere of the street.
Place to stay in Centro
4.93 out of 5 average rating, 435 reviews

Colonial Jewel with Balcony in Old City’s Heart

Experience a Stunning 17th-century Grand Colonial Mansion in Cartagena on Beautiful Santo Domingo Street, the Heart of the Historic City. A dream Loft just for you with a Balcony to enjoy the Caribbean vibe, your morning coffee, or a sunset rum. Steps from the main Plazas, Churches, Museums, and The Best Restaurants and Cafés. Exquisitely furnished: living-dining, kitchen, marble floors and bath, hammock, queen bed, premium 100% cotton linens & towels. A Magical, UNFORGETTABLE experience! ✨

Guest favourite
An airy living space features a light-colored sofa with decorative cushions, a coffee table, and a dining area with a circular table and chairs. Large windows allow natural light to fill the room, while a ceiling fan and a chandelier provide comfort. A hammock can be seen strung between two walls.
Flat in Centro
4.9 out of 5 average rating, 120 reviews

Chic Colonial Retreat – Walk Everywhere

Welcome to my cozy colonial apartment in Cartagena’s Old Town, just steps from Santo Domingo Square. This is my home, and I’ll make sure everything is clean and ready for your stay. Perfect for couples or solo travelers, the apartment includes: ❄️ Two air conditioning units for your comfort 👩‍🍳 Fully equipped kitchen 🚿 Hot water. 🛏️ Comfy double bed 🌿 Spacious colonial balcony 🔐 Digital self check-in 👮‍♂️ Security staff on duty 24/7 🚫 No visitors allowed (per building rules)

Top guest favourite
A modern living space features a stylish dining area with a large table surrounded by light-colored chairs. Above, a well-lit kitchen is visible, complemented by a cozy seating area with armchairs. Exposed stone walls add texture, while pendant lights provide a warm glow.
Apartment in Centro
4.96 out of 5 average rating, 472 reviews

Luxury Duplex · Best Location Historic Center

Exclusive duplex apartment located on the second floor of a majestic republican-era building, a true architectural gem from the early 20th century. Enjoy a privileged view of iconic Calle del Cuartel and immerse yourself in the charm of the Historic Center. Fully equipped with air conditioning throughout, Smart TVs in bedrooms and living area, high-speed WiFi, a complete kitchen, linens, towels, and hot water. Prime location steps from top restaurants, cafés, and Cartagena nightlife.

Top guest favourite
A serene pool area is surrounded by tropical greenery, featuring a circular plant island at the center. Plush seating is available beside the pool, with draped curtains providing a sense of privacy. Soft lighting highlights the textured walls, creating a calming ambiance.
Home in Centro
4.91 out of 5 average rating, 232 reviews

Private Heated Pool+Jacuzzi | Colonial Walled City

Step into one of Cartagena's most iconic streets — Calle de las Damas — and into a beautifully appointed colonial home that blends centuries of history with every modern comfort. Located in the heart of the Walled City, Casa Calle de las Damas is the perfect base for experiencing the real magic of Cartagena. Whether you're traveling with family or a group of friends, this spacious 2-bedroom, 2 1/2-bathroom home offers an elegant and relaxed atmosphere you'll never want to leave.

Top guest favourite
A rooftop terrace features a relaxing hot tub surrounded by lush greenery. Comfortable seating areas include wicker chairs and a wooden table, with stunning views of the city skyline and distant hills under a clear blue sky.
Home in Getsemany
4.99 out of 5 average rating, 128 reviews

Casa O Getsemani Luxury Boutique House

Welcome to Casa O Getsemani! Immerse yourself in luxury at this new 4-story haven in in the coolest neighborhoods.Designed by the renowned architect Vladimir Caballero, our house accommodates 6 guests with utmost comfort. Enjoy complimentary delicious breakfast, airport transfer and attentive housekeepers. Elevate your stay with optional catering, entertainment, and exciting tours. Your unforgettable getaway awaits! Book now and create beautiful memories at Casa O Getsemani.

Top guest favourite
A spacious loft suite is presented with an open layout, featuring a modern spiral staircase leading to a lofted sleeping area. Soft neutral tones and green plant decor enhance the environment. Seating arrangements include a large, curvy couch and a wooden table, creating a comfortable gathering space.
Flat in Centro
5.0 out of 5 average rating, 105 reviews

Luxury Suite/Loft Apt/CityCenter

1 BR Loft Suite in the heart of Cartagena inspired by some of the finest 5 star Hotels in the world. Located inside the walls of the old city, within walking distance to shops, entertainment, restaurants, nightclubs & bars. Enjoy staying in this Unesco Heritage town full of history & excitement. Fully equipped kitchen with Washer/Dryer, Queen Sized Bed, TV, Netflix and 400MbWi-Fi. Our modern beach vibe apartment is perfect for a couple to enjoy and relax Insta @pombocartagena

Guest favourite
Flat in Centro
4.96 out of 5 average rating, 457 reviews

Boutique Stay in Historic Center + Local Concierge

Stay in the heart of Cartagena with a curated local experience. Your stay includes access to a private concierge who can help design your trip—from hidden restaurants to unforgettable moments. Recently redecorated 2-bedroom apartment with full A/C, a bright and relaxed atmosphere, Smart TV, PS4, dining for six, and 24/7 security. Steps from vibrant plazas, cafés, and historic landmarks—your Caribbean retreat awaits.

Guest favourite
A rooftop terrace is presented with a spiral staircase, leading to additional levels. A private pool is featured along one side, complemented by lounge chairs and a sofa. Soft lighting highlights the terracotta walls, enhancing the evening ambiance.
Home in Centro
4.88 out of 5 average rating, 156 reviews

casa encantada

Walled city. Magnificent four-story house exclusively for guests. With a small private pool in the Rooftop. Located in the historic center of the walled city of Cartagena near the Baruco restaurant, bars, galleries, house of the inquisition, Plaza Botero, clock tower, shops, pharmacies, art with a spectacular viewpoint. With air conditioning in the living room, kitchen and bedrooms.

Guest favourite
A spacious living area is characterized by high ceilings with wooden beams and a large chandelier. Comfortable seating is provided with two armchairs and a sofa. A wooden table with an artistic design sits in the center, complemented by a bar area in the background.
Flat in Centro
4.88 out of 5 average rating, 670 reviews

School House

A charming two bedroom, 2.5 bathroom apartment in the center of the Old Town, a few steps from Cartagena’s coveted museums, restaurants, galleries and shops. The property includes a large living room, dining area, kitchen, and balcony overlooking picturesque colonial streets. Housekeeping is included (every other day) to ensure a stress-free stay (except Sundays & holidays).

Guest favourite
Flat in Centro
4.88 out of 5 average rating, 217 reviews

2B in Heart of Old Walled City. Views & Pool.

Captivating 2 bed and 2.5 bath apt in the heart of the Walled City. The property is an apt on the 2nd floor of La Encantada, a colonial home with 100+ yr history. Highly rated restaurants, shops and museums steps away. Great views with two terraces (--private--) and a small pool (--shared--). Max 4 guests. The apt does NOT have hot water. Flexible check in time.

Guest favourite
A rooftop terrace features a relaxing Jacuzzi surrounded by lounge chairs, with vibrant greenery nearby. The scene is enhanced by a stunning sunset and a historic tower in the background, creating a serene atmosphere for relaxation.
Flat in Centro
4.98 out of 5 average rating, 225 reviews

Exclusive Apt in Walled City | Rooftop Jacuzzi!

Welcome to this EXCLUSIVE apartment right in the heart of the Walled city. Just steps away from restaurants, bars, coffee shops and some of the most iconic plazas, churches and museums. Perfect for weekend getaways, business trips, working nomads or cozy home base while exploring everything Cartagena has to offer! NO UNREGISTERED VISITORS ALLOWED!

Popular amenities for holiday rentals near Plaza de Santo Domingo