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Holiday rentals in Santa Clara

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Clara

Guests agree: these stays are highly rated for location, cleanliness and more.

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Home in Gamboa

4.86 out of 5 average rating, 87 reviews

BirdHouse@ Gamboa Panamá Canal

Explore the wonders of the Panama rainforest and return to our magical tropical home! This unique house and pool is a wonderful place to escape the hustle of Panama City, celebrate nature, and enjoy family and friends. Gamboa is a safe, quiet town embedded in the Soberania National Park; it is the entry point to Pipeline Road, some of the best birding in the world. Or take leave of the forest and watch manatee, while fishing for peacock bass in Gatun Lake or paddling kayaks up the Chagres River.

21–28 Nov

$497 SGD per night

Guest favourite

Guest house in Gamboa

4.95 out of 5 average rating, 56 reviews

Gamboa Toucan Apartment casa # 126

Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

24–31 Oct

$118 SGD per night

Guest favourite

Home in Costa Esmeralda

4.96 out of 5 average rating, 104 reviews

Beach House-Amazing Pool, Surf & Pet Friendly

Majestic Sand! Come relax with the whole family at this piece of paradise. Majestic Sand is located in a private beach community in Costa Esmeralda, San Carlos District, Panama. It is located a few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, Santa Clara and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool with multiple hammocks with views of amazing palm trees.

2–9 Jun

$255 SGD per night

Earthen home in El Cope, Penonome

4.91 out of 5 average rating, 145 reviews

Beautiful Eco House in Panama

We are very pleased to offer our beautiful, modern, comfortable house designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and escape daily stress. It is in a beautiful part of Panama near a cloud forest national park. The house sits in 17 acres of forest and has 2 rivers for swimming. The house is very open allowing full enjoyment of nature. There are amazing hiking opportunities in the mountains with waterfalls and visits to local communities.

16–23 Jul

$289 SGD per night

Guest favourite

Guest suite in Gamboa

4.95 out of 5 average rating, 77 reviews

Beautiful annex in the middle of Gamboa Rainforest

Disfruta de la naturaleza sin salir de casa en este histórico poblado ubicado en Parque Soberanía y a orillas del canal de Panamá. A escasos 40min de la estresante capital, podrás relajarte paseando, observando pájaros en Pipeline, kayaking, pescando en el río Chagres, en la isla de los monos, visitando un poblado indígena u observando perezosos. También los amantes de la bicicleta encontrarán su lugar. En las noches, toma un baño relajante y duerme plácidamente.

9–16 Feb

$99 SGD per night

Guest favourite

Home in Taboga Island

4.96 out of 5 average rating, 140 reviews

Casa Rosie - Taboga dream home

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

14–21 Jul

$330 SGD per night

Guest favourite

Home in Las Colinas de Caceres de Arraijan

4.98 out of 5 average rating, 196 reviews

Tropical Haven with Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

30 Aug – 6 Sep

$427 SGD per night

Home in Vista Mar Golf, Beach & Marina

4.88 out of 5 average rating, 224 reviews

Luxurious Beach House - Private Pool Golf & Marina

Vista Mar Golf, Beach & Marina is a gated community with private security, with direct access to a state of the art golf course designed by J. Michael Poellot. It also has marina, heliport, tennis courts, direct private beach access, bars and restaurants. The house comes with an outdoor private pool & hot tub, also a amazing private outdoor kitchen, and an amazing sea view with spectacular sunrises and sunsets.

21–28 Nov

$1,017 SGD per night

Guest favourite

Loft in Panamá

4.94 out of 5 average rating, 52 reviews

Canal Loft

Apartamento en 1er Piso, ideal para parejas amantes del buen gusto, tranquilidad y confort. Cerca del apartamento hay senderos hacia el el Canal de Panamá, colinas y selva. Apartment on the 1st Floor, ideal for couples who love good taste, tranquility and comfort. Near the apartment there are trails to the Panama Canal, hills and jungle.

22–29 Apr

$89 SGD per night

Holiday home in Arraiján

4.8 out of 5 average rating, 45 reviews

Apartment In Club De Playa, with Pool and BBQ

Relax with the whole family or friends in this quiet place to stay and spend beautiful days at the pool, beach, breeze and sea. Enjoy a beautiful landscape surrounded by mountains, walks on the beach sand, lake trails, enjoy a lakefront barbecue, playground or a waterfront barbecue on beautiful ranches.

22–29 Nov

$102 SGD per night

Guest favourite

Townhouse in Panama

4.94 out of 5 average rating, 127 reviews

Unique Historic House in Casco

Hip five bedroom house in the heart of Casco Antiguo. Designed by world renowned restoration architect; this house is a perfect spot for exploring Panama's wonders. Ideal for families wanting to spend some time around the vibrant historic area.

6–13 Oct

$877 SGD per night

Holiday rentals for every style

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Popular amenities for Santa Clara holiday rentals

Free parking on premises

Air conditioning

Other great holiday rentals in Santa Clara

Guest favourite

Chalet in Veracruz

4.89 out of 5 average rating, 92 reviews

A beachfront property very near to Panama city

5–12 Jul

$88 SGD per night

Guest favourite

Guest house in El Valle de Antón

5.0 out of 5 average rating, 28 reviews

Spacious Casita with Bamboo View

25 Jun – 2 Jul

$121 SGD per night

Guest favourite

Home in Panamá Oeste

4.97 out of 5 average rating, 63 reviews

Casa de Playa AX8 close to town!

29 Jan – 5 Feb

$148 SGD per night

Guest favourite

Cottage in Panamá

4.95 out of 5 average rating, 20 reviews

Modern House in Altos de Cerro Azul with 2 rooms

3–10 Jun

$186 SGD per night

Guest favourite

Home in Río Hato

4.95 out of 5 average rating, 75 reviews

Spectacular beachfront house in Buenaventura!

3–10 Oct

$937 SGD per night

Guest favourite

Home in San Carlos

4.93 out of 5 average rating, 86 reviews

Beach House-Ocean View Rooftop Jacuzzi & Pool

26 Jul – 2 Aug

$385 SGD per night

Guest favourite

Serviced apartment in Panamá

5.0 out of 5 average rating, 59 reviews

Cozy n Comfy con balcón in the heart of Casco

24–31 Oct

$157 SGD per night

Guest favourite

Cottage in Altos del Maria

4.93 out of 5 average rating, 96 reviews

Cabin with Spectacular Mountain View

2–9 Dec

$460 SGD per night

Destinations to explore