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Holiday rentals in San Antonio

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Top-rated holiday rentals in San Antonio

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Top guest favourite
An open living area features high ceilings and a striking wooden staircase leading to the upper level. Below, a well-equipped kitchen is arranged with modern bar stools, while a cozy seating area is accentuated by a patterned rug and a decorative plant nearby.
Home in San Cayetano
5 out of 5 average rating, 46 reviews

Colonial House | Historic Center | Cristo Rey View

Welcome to La Casa de Río! A colonial refuge where warm light embraces and the tropical breathes in every corner. In December, Cali wakes up magical: sweet breeze, bright colors and nights that beat to the rhythm of salsa. If you want to live an authentic Caleña experience — culture, flavor, rhythm and human warmth — this is the place. We are in the heart of the Historic Center, within walking distance of restaurants, cafes, and salsa bars. Here you'll find premium rest and a perfect home for up to 6 travelers.

Guest favourite
An open living area features a modern kitchen island with a cooktop, surrounded by wicker chairs and natural light from large panoramic windows. Exposed wooden beams add character to the space, complemented by decorative elements like a wall sculpture and pendant lamps.
Flat in San Antonio
4.96 out of 5 average rating, 27 reviews

Panoramic Suite Overlooking Colonial Cali

Magical View Suite – Colonial Design in San Antonio Experience the soul of Cali from this cozy suite with an unforgettable view In the historic heart of San Antonio, just steps from Hotel Colina, the space blends colonial charm, local art, and a serene atmosphere designed for rest and inspiration Perfect for travelers seeking history, culture, and gastronomy without giving up modern comforts: a fully equipped kitchen, hot water, reliable Wi-Fi, and a postcard-perfect view from the window

Guest favourite
A bright sleeping area features a spacious bed adorned with decorative pillows. Exposed brick arches highlight the stylish design. Soft lighting is provided by a hanging lamp, while natural light enters from a nearby window, illuminating warm wooden floors.
Flat in San Antonio
4.87 out of 5 average rating, 76 reviews

Beautiful Colonial Apartment San Antonio Centre

The house is right in the middle of San Antonio, but without having to walk up any of the area's steep hills. Beautiful, tranquil Colonial home with original architecture located in Cali's most popular neighbourhood. This oasis has a running fountain. The house has this private apartment and three separate bedrooms. Here you are only seconds away from restaurants, cafes, bars, a park and salsa schools. The house has two floors with different areas to socialise, chill, read and work.

Guest favourite
A modern living area features a spacious white table paired with two black chairs. A light-colored sofa provides additional seating. Artistic wall decor complements the neutral color palette, while a large mirror enhances natural light and visual depth in the space.
Flat in San Antonio
4.89 out of 5 average rating, 44 reviews

Luxury apartment in the Peñon

Luxury apartment located in the exclusive El Peñón neighborhood, the heart of the traditional hotel area of western Cali. Surrounded by a variety of restaurants, bars, nightclubs and cultural areas, close to emblematic sites such as the La Tertulia Museum, the Obelisk, the Cali Zoo, the Cerro de las Tres Cruces, the Gato del Río, the Bulevar del Río, San Antonio and Granada. Perfect for those looking for comfort, style and an unbeatable location to enjoy and explore the city.

Guest favourite
Flat in San Antonio
4.87 out of 5 average rating, 128 reviews

Luxurious Studio in San Antonio

Indulge in the unmatched luxury of this recently renovated studio, boasting a unique and truly extraordinary style. Perfect for those in search of comfort and relaxation without compromising on location, this studio is nestled in the heart of San Antonio, Cali's most distinguished neighborhood. Immerse yourself in a lively setting surrounded by the city's finest local restaurants and a captivating atmosphere. It presents an exceptional combination of opulence and convenience.

Top guest favourite
A well-lit bedroom features a spacious bed draped in crisp white linens and accented with decorative pillows. A green accent wall provides a fresh touch, while large glass doors lead to a balcony with views of surrounding trees, adding to the room's inviting atmosphere.
Flat in El Peñol
4.97 out of 5 average rating, 181 reviews

Villa del Peñon 301 - 2-Bed With Nice Balcony

🌴 EXSTR APARTMENT • Villa del Peñon 301 This two bedroom, two bathroom unit with a balcony, is the perfect match for families, groups of friends, or digital nomads. All tabs have hot water, the bedroom has A/C, smart TV, and a queen bed. All the amenities are in place and have been designed with your comfort in mind. The El Peñon neighborhood is a very walkable area with plenty of restaurants and entertainment within minutes. Colonial San Antonio is only 3 blocks away.

Top guest favourite
Flat in San Antonio
4.96 out of 5 average rating, 161 reviews

OM Studio Rooftop at San Antonio - Cali.

Om Studio Rooftop es un lugar para disfrutar de la tranquilidad y del ambiente que tiene. Deléitate con la brisa que baja de las montañas y el canto de los loros al atardecer, acompáñalo con una copa de vino, complácete con una taza de café al despertar, toma una ducha al aire libre y gózate el sol en la terraza en las mañanas. En las noches aprovecha todo lo que tiene el barrio San Antonio para darte. Un espacio único en el corazón de la sucursal del cielo.

Guest favourite
A dining setup is presented on a stylish terrace table, featuring a plate of pasta and cured meats alongside a bottle of red wine and glasses. A decorative vase with an orchid adds a touch of elegance, with a panoramic view of the city landscape in the background.
Flat in San Antonio
4.95 out of 5 average rating, 66 reviews

Private Patio & Rooftop with Design in San Antonio

Ubicado en el emblematico barrio San Antonio, cerca del Bulevar, la gastronomía y la salsa a pocos minutos y muy cerca del Hotel Intercontinental. Después del plan, vuelve a nuestro apartamento: una experiencia con acabados modernos, ambiente silencioso y cómodo, diseñada para descansar o trabajar remoto. Patio privado con mesa exterior para respirar y desconectar. Y como extra, una terraza en el tercer piso, ideal para ver atardeceres con vista a la ciudad.

Guest favourite
Flat in San Antonio
4.88 out of 5 average rating, 83 reviews

402Studio con balcón en zona top + AC y Netflix

Located in El Peñón, one of the safest and quietest neighborhoods in Cali. Steps from the 5-star Dann Carlton Hotel, surrounded by restaurants, bars, nightclubs, casino, museum and park. We have air conditioning, fast WiFi, TV with streaming apps and a free 24/7 laundry area. You can hear the passing of vehicles. Ideal for enjoying the city in comfort and an excellent location. In addition, we offer a clean, cozy environment with quick attention to any need.

Guest favourite
A modern apartment interior features a cozy seating area with a dark sofa adorned with red decorative pillows. A compact kitchen is equipped with appliances and a small dining table with red chairs. Natural light streams through sheer curtains, illuminating the wooden flooring.
Flat in San Antonio
4.91 out of 5 average rating, 136 reviews

Apartment 202 San Antonio

Beautiful furnished apartment in the San Antonio neighborhood of Cali, with its privileged in the tourist sector, you will have access to the best restaurants, parks and theaters in the city in a few minutes. Additionally, the apartment is equipped with everything necessary for you to enjoy a comfortable stay. Don't hesitate to book and enjoy all that Cali has to offer! I'm here to help you with whatever you need!

Top guest favourite
Flat in San Cayetano
4.98 out of 5 average rating, 41 reviews

Chic Apartment with Private Terrace in San Antonio

Welcome to Cali’s historic San Antonio district. This early-1900s home was thoughtfully restored into a modern, chic condo in 2023. Located in a private 5-unit building, it offers comfort and character just steps from cafés, galleries, and local cuisine. Feel the Cali breeze, walk to top salsa spots, and experience the city like a local. Your Cali-born host is happy to assist in English or Spanish.

Guest favourite
An open-plan living space features a dining table with four chairs adjacent to a modern kitchen. A comfortable sofa is positioned nearby, and large sliding glass doors showcase outdoor greenery. Warm lighting creates a cozy atmosphere, complemented by decorative elements like natural fibers.
Flat in Centenario
4.93 out of 5 average rating, 113 reviews

IN105 Luxury Oasis | Private Jacuzzi | 350mb WIFI

** EXCLUSIVE UNIT WITH NO AIRBNB SERVICE FEE ** Welcome to our luxurious loft in Cali, inspired by nature. With 44m², a private outdoor Jacuzzi and space for 4 people, it is a contemporary oasis. Living room, dining room, and equipped kitchen offer comfort and style. A private room and full bathroom guarantee a restful night's sleep. Unbeatable location near tourist spots.

Popular amenities for San Antonio holiday rentals

  1. Airbnb
  2. Colombia
  3. Valle del Cauca
  4. Cali
  5. San Antonio