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Holiday rentals in San Antonio

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Top-rated holiday rentals in San Antonio

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Top guest favourite
An open living area features high ceilings and a striking wooden staircase leading to the upper level. Below, a well-equipped kitchen is arranged with modern bar stools, while a cozy seating area is accentuated by a patterned rug and a decorative plant nearby.
Home in San Cayetano
5 out of 5 average rating, 49 reviews

Colonial House | Historic Center | Cristo Rey View

Welcome to La Casa de Río! A colonial refuge where warm light embraces and the tropical breathes in every corner. In December, Cali wakes up magical: sweet breeze, bright colors and nights that beat to the rhythm of salsa. If you want to live an authentic Caleña experience — culture, flavor, rhythm and human warmth — this is the place. We are in the heart of the Historic Center, within walking distance of restaurants, cafes, and salsa bars. Here you'll find premium rest and a perfect home for up to 6 travelers.

Guest favourite
A staircase with black metal steps leads upward, set against a backdrop of exposed brick wall. Natural light flows through large wooden windows with bars, illuminating a decorative plant in a woven basket and a glass bottle on the floor.
Flat in San Antonio
4.89 out of 5 average rating, 64 reviews

Cozy+Unique Loft/Touch of Nature/High Speed WiFi

*BRAND NEW* rustic yet luxurious & modern loft located in San Antonio. Walking distance from Cali's best restaurants, top bars/night clubs! Centrally located in Cali's famous artistic & colonial neighborhood of San Antonio, this chic loft comes equipped with everything you need for a comfortable stay. Full kitchen, queen sized beds, workspace, AC, washer, Smart TV, & more! If you are looking for a true cultural urban experience, with all of the amenities & comfort, then this is your place.

Guest favourite
An open living area features a modern kitchen island with a cooktop, surrounded by wicker chairs and natural light from large panoramic windows. Exposed wooden beams add character to the space, complemented by decorative elements like a wall sculpture and pendant lamps.
Flat in San Antonio
4.96 out of 5 average rating, 27 reviews

Panoramic Suite Overlooking Colonial Cali

Magical View Suite – Colonial Design in San Antonio Experience the soul of Cali from this cozy suite with an unforgettable view In the historic heart of San Antonio, just steps from Hotel Colina, the space blends colonial charm, local art, and a serene atmosphere designed for rest and inspiration Perfect for travelers seeking history, culture, and gastronomy without giving up modern comforts: a fully equipped kitchen, hot water, reliable Wi-Fi, and a postcard-perfect view from the window

Guest favourite
A bright sleeping area features a spacious bed adorned with decorative pillows. Exposed brick arches highlight the stylish design. Soft lighting is provided by a hanging lamp, while natural light enters from a nearby window, illuminating warm wooden floors.
Flat in San Antonio
4.87 out of 5 average rating, 79 reviews

Beautiful Colonial Apartment San Antonio Centre

The house is right in the middle of San Antonio, but without having to walk up any of the area's steep hills. Beautiful, tranquil Colonial home with original architecture located in Cali's most popular neighbourhood. This oasis has a running fountain. The house has this private apartment and three separate bedrooms. Here you are only seconds away from restaurants, cafes, bars, a park and salsa schools. The house has two floors with different areas to socialise, chill, read and work.

Superhost
A modern living area features a comfortable sectional sofa and an oversized ottoman on a plush area rug. Natural light filters through the window blinds, complemented by warm lighting along the walls. A dining bar with three stylish stools creates a versatile space for meals or work.
Flat in San Antonio
4.8 out of 5 average rating, 107 reviews

Beautiful apartment in El Peñon

Luxury apartment located in the exclusive El Peñón neighborhood, the heart of the traditional hotel area of western Cali. Surrounded by a variety of restaurants, bars, nightclubs and cultural areas, close to emblematic sites such as the La Tertulia Museum, the Obelisk, the Cali Zoo, the Cerro de las Tres Cruces, the Gato del Río, the Bulevar del Río, San Antonio and Granada. Perfect for those looking for comfort, style and an unbeatable location to enjoy and explore the city.

Guest favourite
A well-appointed bedroom features a queen bed with white linens and a soft knit throw, complemented by two bedside lamps. Built-in storage is present above the bed, with a calming yellow accent wall visible. A doorway leads to an adjoining kitchen area.
Flat in El Peñol
4.9 out of 5 average rating, 217 reviews

Villa del Peñon 302 - 1-Bed With Quiet Comfort

🌴 EXSTR APARTMENT • Villa del Peñon 302 This quiet one bedroom, one bathroom internal unit, is the perfect match for for solo travelers, couples or digital nomads. All tabs have hot water, the bedroom has A/C, smart TV, and a queen bed. All the amenities are in place and it has been designed with your comfort in mind. The El Peñon neighborhood is a very walkable area with plenty of restaurants and entertainment within minutes. Colonial San Antonio is only 3 blocks away.

Top guest favourite
Flat in San Antonio
4.96 out of 5 average rating, 167 reviews

OM Studio Rooftop at San Antonio - Cali.

Om Studio Rooftop es un lugar para disfrutar de la tranquilidad y del ambiente que tiene. Deléitate con la brisa que baja de las montañas y el canto de los loros al atardecer, acompáñalo con una copa de vino, complácete con una taza de café al despertar, toma una ducha al aire libre y gózate el sol en la terraza en las mañanas. En las noches aprovecha todo lo que tiene el barrio San Antonio para darte. Un espacio único en el corazón de la sucursal del cielo.

Guest favourite
Flat in San Antonio
4.91 out of 5 average rating, 100 reviews

401Encantador studio con gran balcón + AC y Wi-Fi

Located in El Peñón, one of the safest and quietest neighborhoods in Cali. Steps from the 5-star Dann Carlton Hotel, surrounded by restaurants, bars, nightclubs, casino, museum and park. We have air conditioning, fast WiFi, TV with streaming apps and a free 24/7 laundry area. You can hear the passing of vehicles. Ideal for enjoying the city in comfort and an excellent location. In addition, we offer a clean, cozy environment with quick attention to any need.

Guest favourite
A terrace showcases a spacious seating arrangement under a large umbrella, featuring two stylish chairs and a coffee table. Lush greenery lines the area, while a view of the city skyline and neighboring buildings is visible in the background.
Serviced apartment in Centenario
4.87 out of 5 average rating, 146 reviews

Apartamento boutique con terraza y jacuzzi privado

IG @bestairbnbcali (videos) A 7 minutos del centro de la ciudad encuentras este amplio apartamento con diseño nórdico en la mejor ubicación de la ciudad en el barrio centenario/granada cercano a todos los sitios turísticos, tiene terraza con vistas al oeste de Cali y al cerro de las tres cruces, Jacuzzi privado y pantalla de TV gigante, a una cuadra el mall centenario, cerca de bares y restaurantes. Por favor leer las reglas antes de reservar

Guest favourite
Flat in San Antonio
4.89 out of 5 average rating, 109 reviews

Exceptional Study San Antonio

Immerse yourself in the unparalleled luxury of this newly renovated studio with a unique style, truly out of this world. Ideal for those seeking comfort and relaxation without sacrificing location, this studio is located in the heart of San Antonio, the most prominent area of Cali. Enjoy a vibrant environment with the city's best local restaurants and a captivating atmosphere. Offering an extraordinary blend of opulence and convenience.

Top guest favourite
Flat in San Cayetano
4.98 out of 5 average rating, 46 reviews

Chic Apartment with Private Terrace in San Antonio

Welcome to Cali’s historic San Antonio district. This early-1900s home was thoughtfully restored into a modern, chic condo in 2023. Located in a private 5-unit building, it offers comfort and character just steps from cafés, galleries, and local cuisine. Feel the Cali breeze, walk to top salsa spots, and experience the city like a local. Your Cali-born host is happy to assist in English or Spanish.

Guest favourite
An open-plan living space features a dining table with four chairs adjacent to a modern kitchen. A comfortable sofa is positioned nearby, and large sliding glass doors showcase outdoor greenery. Warm lighting creates a cozy atmosphere, complemented by decorative elements like natural fibers.
Flat in Centenario
4.93 out of 5 average rating, 120 reviews

IN105 Luxury Oasis | Private Jacuzzi | 350mb WIFI

** EXCLUSIVE UNIT WITH NO AIRBNB SERVICE FEE ** Welcome to our luxurious loft in Cali, inspired by nature. With 44m², a private outdoor Jacuzzi and space for 4 people, it is a contemporary oasis. Living room, dining room, and equipped kitchen offer comfort and style. A private room and full bathroom guarantee a restful night's sleep. Unbeatable location near tourist spots.

Popular amenities for San Antonio holiday rentals

  1. Airbnb
  2. Colombia
  3. Valle del Cauca
  4. Cali
  5. San Antonio