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Holiday rentals in San Antonio

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Top-rated holiday rentals in San Antonio

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
An open living area features high ceilings and a striking wooden staircase leading to the upper level. Below, a well-equipped kitchen is arranged with modern bar stools, while a cozy seating area is accentuated by a patterned rug and a decorative plant nearby.
Home in San Cayetano
5 out of 5 average rating, 44 reviews

Colonial House | Historic Center | Cristo Rey View

Welcome to La Casa de Río! A colonial refuge where warm light embraces and the tropical breathes in every corner. In December, Cali wakes up magical: sweet breeze, bright colors and nights that beat to the rhythm of salsa. If you want to live an authentic Caleña experience — culture, flavor, rhythm and human warmth — this is the place. We are in the heart of the Historic Center, within walking distance of restaurants, cafes, and salsa bars. Here you'll find premium rest and a perfect home for up to 6 travelers.

Guest favourite
A rooftop terrace is depicted with a dining table set for breakfast. A plate with a croissant and a glass of orange juice sit beside a mug. The background features city buildings under a partly cloudy sky, enhancing the urban atmosphere.
Flat in San Antonio
4.94 out of 5 average rating, 67 reviews

Céntrico y Silencioso: Patio Privado & Azotea

Viví el encanto de San Antonio: Bulevar, gastronomía y salsa, con la tranquilidad que buscas para descansar. En nuestro exclusivos apartamento cómodo y con diseño Arquitectónico. Silencioso para relajarte o trabajar remoto.Ubicado en zona turística, este espacio cuenta con un plus difícil de encontrar en el centro: patio privado con comedor exterior, perfecto para desayunar o cenar al aire libre. Además, tendrás acceso a la terraza del edificio en el tercer piso, para ver hermosos atardeceres.

Guest favourite
A staircase with black metal steps leads upward, set against a backdrop of exposed brick wall. Natural light flows through large wooden windows with bars, illuminating a decorative plant in a woven basket and a glass bottle on the floor.
Flat in San Antonio
4.89 out of 5 average rating, 62 reviews

Cozy+Unique Loft/Touch of Nature/High Speed WiFi

*BRAND NEW* rustic yet luxurious & modern loft located in San Antonio. Walking distance from Cali's best restaurants, top bars/night clubs! Centrally located in Cali's famous artistic & colonial neighborhood of San Antonio, this chic loft comes equipped with everything you need for a comfortable stay. Full kitchen, queen sized beds, workspace, AC, washer, Smart TV, & more! If you are looking for a true cultural urban experience, with all of the amenities & comfort, then this is your place.

Guest favourite
A bright sleeping area features a spacious bed adorned with decorative pillows. Exposed brick arches highlight the stylish design. Soft lighting is provided by a hanging lamp, while natural light enters from a nearby window, illuminating warm wooden floors.
Flat in San Antonio
4.87 out of 5 average rating, 76 reviews

Beautiful Colonial Apartment San Antonio Centre

The house is right in the middle of San Antonio, but without having to walk up any of the area's steep hills. Beautiful, tranquil Colonial home with original architecture located in Cali's most popular neighbourhood. This oasis has a running fountain. The house has this private apartment and three separate bedrooms. Here you are only seconds away from restaurants, cafes, bars, a park and salsa schools. The house has two floors with different areas to socialise, chill, read and work.

Top guest favourite
A modern living area features a spacious white table paired with two black chairs. A light-colored sofa provides additional seating. Artistic wall decor complements the neutral color palette, while a large mirror enhances natural light and visual depth in the space.
Flat in San Antonio
4.92 out of 5 average rating, 37 reviews

Luxury apartment in the Peñon

Luxury apartment located in the exclusive El Peñón neighborhood, the heart of the traditional hotel area of western Cali. Surrounded by a variety of restaurants, bars, nightclubs and cultural areas, close to emblematic sites such as the La Tertulia Museum, the Obelisk, the Cali Zoo, the Cerro de las Tres Cruces, the Gato del Río, the Bulevar del Río, San Antonio and Granada. Perfect for those looking for comfort, style and an unbeatable location to enjoy and explore the city.

Top guest favourite
Flat in San Antonio
4.96 out of 5 average rating, 161 reviews

OM Studio Rooftop at San Antonio - Cali.

Om Studio Rooftop es un lugar para disfrutar de la tranquilidad y del ambiente que tiene. Deléitate con la brisa que baja de las montañas y el canto de los loros al atardecer, acompáñalo con una copa de vino, complácete con una taza de café al despertar, toma una ducha al aire libre y gózate el sol en la terraza en las mañanas. En las noches aprovecha todo lo que tiene el barrio San Antonio para darte. Un espacio único en el corazón de la sucursal del cielo.

Top guest favourite
A relaxing jacuzzi area is showcased, featuring a grey hot tub surrounded by wooden decking. A potted plant adds a touch of greenery, while neatly stacked towels are placed nearby. A crate of drinks sits next to the tub, enhancing the inviting atmosphere.
Flat in El Peñol
4.97 out of 5 average rating, 195 reviews

Villa del Peñon 203 - Private Jacuzzi Pad Near Fun.

🌴 EXSTR APARTMENT • Villa del Peñon 203 This one bedroom, one bathroom jacuzzi unit with a balcony, is the perfect match for for solo travelers, couples or digital nomads. All tabs have hot water, the bedroom has A/C, smart TV, and a queen bed. All the amenities are in place and designed with your comfort in mind. The El Peñon neighborhood is a very walkable area with plenty of restaurants and entertainment within minutes. Colonial San Antonio is only 3 blocks away.

Superhost
A terrace showcases a spacious seating arrangement under a large umbrella, featuring two stylish chairs and a coffee table. Lush greenery lines the area, while a view of the city skyline and neighboring buildings is visible in the background.
Serviced apartment in Centenario
4.87 out of 5 average rating, 139 reviews

Apartamento boutique con terraza y jacuzzi privado

IG @bestairbnbcali (videos) 7 minutes from the city center you will find this spacious apartment with Nordic design in the best location in the city in the centenario/granada neighborhood near all the tourist sites, it has a terrace overlooking the west of Cali and the hill of the three crosses, private Jacuzzi and giant TV screen, one block from the centenario mall, near bars and restaurants. No parties due to Airbnb regulations.

Top guest favourite
Home in San Antonio
5 out of 5 average rating, 30 reviews

Colonial house in San Antonio, excellent location

Three blocks from the church of San Antonio. Stay in our two-room studio apartment located in the oldest and most touristy area of old Cali, in colonial San Antonio, surrounded by a variety of craft markets, viewpoints, restaurants with a great gastronomic diversity and cafes. Close to the city's iconic tourist spots, you can enjoy the boulevard, Parque del Gato, Calle de la Salsa, and museums on foot. FAMILY ENVIRONMENT

Guest favourite
A modern apartment interior features a cozy seating area with a dark sofa adorned with red decorative pillows. A compact kitchen is equipped with appliances and a small dining table with red chairs. Natural light streams through sheer curtains, illuminating the wooden flooring.
Flat in San Antonio
4.91 out of 5 average rating, 136 reviews

Apartment 202 San Antonio

Beautiful furnished apartment in the San Antonio neighborhood of Cali, with its privileged in the tourist sector, you will have access to the best restaurants, parks and theaters in the city in a few minutes. Additionally, the apartment is equipped with everything necessary for you to enjoy a comfortable stay. Don't hesitate to book and enjoy all that Cali has to offer! I'm here to help you with whatever you need!

Guest favourite
An open-plan living space features a dining table with four chairs adjacent to a modern kitchen. A comfortable sofa is positioned nearby, and large sliding glass doors showcase outdoor greenery. Warm lighting creates a cozy atmosphere, complemented by decorative elements like natural fibers.
Flat in Centenario
4.93 out of 5 average rating, 112 reviews

IN105 Luxury Oasis | Private Jacuzzi | 350mb WIFI

** EXCLUSIVE UNIT WITH NO AIRBNB SERVICE FEE ** Welcome to our luxurious loft in Cali, inspired by nature. With 44m², a private outdoor Jacuzzi and space for 4 people, it is a contemporary oasis. Living room, dining room, and equipped kitchen offer comfort and style. A private room and full bathroom guarantee a restful night's sleep. Unbeatable location near tourist spots.

Guest favourite
A modern dining area features a wooden table surrounded by two black woven chairs. A simple vase holds decorative dried foliage, positioned on the table. Stylish cabinetry with warm lighting enhances the contemporary ambiance, complemented by decorative items displayed on the shelves.
Flat in San Antonio
4.91 out of 5 average rating, 116 reviews

Exclusive Duplex Apartment

Welcome to our newly renovated duplex apartment in the heart of San Antonio! Embrace the latest design trends in this luxurious space where comfort meets style. Enjoy the vibrant atmosphere of the city right at your doorstep. Feel at home as you indulge in modern amenities and soak in the energy of this bustling neighborhood. Your perfect urban getaway awaits!

Popular amenities for San Antonio holiday rentals

  1. Airbnb
  2. Colombia
  3. Valle del Cauca
  4. Cali
  5. San Antonio