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Holiday rentals in San Antonio

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Top-rated holiday rentals in San Antonio

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
An open living area features high ceilings and a striking wooden staircase leading to the upper level. Below, a well-equipped kitchen is arranged with modern bar stools, while a cozy seating area is accentuated by a patterned rug and a decorative plant nearby.
Home in San Cayetano
5 out of 5 average rating, 49 reviews

Colonial House | Historic Center | Cristo Rey View

Welcome to La Casa de Río! A colonial refuge where warm light embraces and the tropical breathes in every corner. In December, Cali wakes up magical: sweet breeze, bright colors and nights that beat to the rhythm of salsa. If you want to live an authentic Caleña experience — culture, flavor, rhythm and human warmth — this is the place. We are in the heart of the Historic Center, within walking distance of restaurants, cafes, and salsa bars. Here you'll find premium rest and a perfect home for up to 6 travelers.

Guest favourite
A modern living area is equipped with a spacious light-colored sofa and a coffee table. A large TV mounted on the wall displays the Netflix logo. The adjacent kitchen area features pendant lighting and a bright atmosphere, with a glimpse of outdoor views visible through glass doors.
Flat in El Peñol
4.96 out of 5 average rating, 145 reviews

El Peñon Penthouse - Private Terrace and Cool View

🌴 EXSTR APARTMENT • Brisas del Peñón 401 Stylish 2 bedroom, 2 bathroom penthouse with beautiful views of Cali’s iconic Three Crosses. Enjoy fast 300 Mb Wi-Fi, two workstations (one with electric desk + monitor), SmartTVs, A/C in bedrooms, and noise-reducing windows in the master bedroom. The private terrace features outdoor dining, a BBQ, and a small kitchen — perfect for soaking in Cali’s warm evenings. Located on quiet tree-lined street, steps from Krost bakery and all the best of El Peñon.

Guest favourite
A staircase with black metal steps leads upward, set against a backdrop of exposed brick wall. Natural light flows through large wooden windows with bars, illuminating a decorative plant in a woven basket and a glass bottle on the floor.
Flat in San Antonio
4.89 out of 5 average rating, 64 reviews

Cozy+Unique Loft/Touch of Nature/High Speed WiFi

*BRAND NEW* rustic yet luxurious & modern loft located in San Antonio. Walking distance from Cali's best restaurants, top bars/night clubs! Centrally located in Cali's famous artistic & colonial neighborhood of San Antonio, this chic loft comes equipped with everything you need for a comfortable stay. Full kitchen, queen sized beds, workspace, AC, washer, Smart TV, & more! If you are looking for a true cultural urban experience, with all of the amenities & comfort, then this is your place.

Guest favourite
An open living area features a modern kitchen island with a cooktop, surrounded by wicker chairs and natural light from large panoramic windows. Exposed wooden beams add character to the space, complemented by decorative elements like a wall sculpture and pendant lamps.
Flat in San Antonio
4.96 out of 5 average rating, 27 reviews

Panoramic Suite Overlooking Colonial Cali

Magical View Suite – Colonial Design in San Antonio Experience the soul of Cali from this cozy suite with an unforgettable view In the historic heart of San Antonio, just steps from Hotel Colina, the space blends colonial charm, local art, and a serene atmosphere designed for rest and inspiration Perfect for travelers seeking history, culture, and gastronomy without giving up modern comforts: a fully equipped kitchen, hot water, reliable Wi-Fi, and a postcard-perfect view from the window

Guest favourite
A bright sleeping area features a spacious bed adorned with decorative pillows. Exposed brick arches highlight the stylish design. Soft lighting is provided by a hanging lamp, while natural light enters from a nearby window, illuminating warm wooden floors.
Flat in San Antonio
4.87 out of 5 average rating, 79 reviews

Beautiful Colonial Apartment San Antonio Centre

The house is right in the middle of San Antonio, but without having to walk up any of the area's steep hills. Beautiful, tranquil Colonial home with original architecture located in Cali's most popular neighbourhood. This oasis has a running fountain. The house has this private apartment and three separate bedrooms. Here you are only seconds away from restaurants, cafes, bars, a park and salsa schools. The house has two floors with different areas to socialise, chill, read and work.

Top guest favourite
Flat in San Antonio
4.96 out of 5 average rating, 166 reviews

OM Studio Rooftop at San Antonio - Cali.

Om Studio Rooftop es un lugar para disfrutar de la tranquilidad y del ambiente que tiene. Deléitate con la brisa que baja de las montañas y el canto de los loros al atardecer, acompáñalo con una copa de vino, complácete con una taza de café al despertar, toma una ducha al aire libre y gózate el sol en la terraza en las mañanas. En las noches aprovecha todo lo que tiene el barrio San Antonio para darte. Un espacio único en el corazón de la sucursal del cielo.

Guest favourite
Flat in San Antonio
4.89 out of 5 average rating, 89 reviews

402Studio con balcón en zona top + AC y Netflix

Located in El Peñón, one of the safest and quietest neighborhoods in Cali. Steps from the 5-star Dann Carlton Hotel, surrounded by restaurants, bars, nightclubs, casino, museum and park. We have air conditioning, fast WiFi, TV with streaming apps and a free 24/7 laundry area. You can hear the passing of vehicles. Ideal for enjoying the city in comfort and an excellent location. In addition, we offer a clean, cozy environment with quick attention to any need.

Top guest favourite
A modern living area is presented with a light purple sofa and minimalistic framed artwork featuring a bicycle. A sliding wooden door leads to another space, while a wall-mounted TV is positioned next to a collection of magazines. Natural light filters through the nearby window.
Flat in Centenario
5 out of 5 average rating, 27 reviews

Close to everything, El Peñon, Tourist area |Tina, A/C,

✨ Moderno y acogedor apartamento en el exclusivo barrio el peñon Disfruta caminando el Boulevard del Río, Gato de Tejada, San Antonio, y relajate visitando los mejores restaurantes de Cali, bares y discotecas en la zona. ¡Te esperamos! Nota: Como varios edificios clásicos del Peñón, no tiene ascensor; el acceso es por escaleras. Es ideal para parejas y personas solas que quieren alojarse a pasos de los sitios más emblematicos y divertidos de cali.

Guest favourite
Flat in San Antonio
4.89 out of 5 average rating, 109 reviews

Exceptional Study San Antonio

Immerse yourself in the unparalleled luxury of this newly renovated studio with a unique style, truly out of this world. Ideal for those seeking comfort and relaxation without sacrificing location, this studio is located in the heart of San Antonio, the most prominent area of Cali. Enjoy a vibrant environment with the city's best local restaurants and a captivating atmosphere. Offering an extraordinary blend of opulence and convenience.

Top guest favourite
Flat in San Cayetano
4.98 out of 5 average rating, 46 reviews

Chic Apartment with Private Terrace in San Antonio

Welcome to Cali’s historic San Antonio district. This early-1900s home was thoughtfully restored into a modern, chic condo in 2023. Located in a private 5-unit building, it offers comfort and character just steps from cafés, galleries, and local cuisine. Feel the Cali breeze, walk to top salsa spots, and experience the city like a local. Your Cali-born host is happy to assist in English or Spanish.

Guest favourite
An open-plan living space features a dining table with four chairs adjacent to a modern kitchen. A comfortable sofa is positioned nearby, and large sliding glass doors showcase outdoor greenery. Warm lighting creates a cozy atmosphere, complemented by decorative elements like natural fibers.
Flat in Centenario
4.93 out of 5 average rating, 118 reviews

IN105 Luxury Oasis | Private Jacuzzi | 350mb WIFI

** EXCLUSIVE UNIT WITH NO AIRBNB SERVICE FEE ** Welcome to our luxurious loft in Cali, inspired by nature. With 44m², a private outdoor Jacuzzi and space for 4 people, it is a contemporary oasis. Living room, dining room, and equipped kitchen offer comfort and style. A private room and full bathroom guarantee a restful night's sleep. Unbeatable location near tourist spots.

Guest favourite
Flat in Cali
5 out of 5 average rating, 14 reviews

Spectacular Apartment, Prime Location

Located in heart of colonial neighborhood this newly renovated, peaceful and luxurious apartment benefits from generous stylish space and fully equipped kitchen. Even though it's located in proximity to all the best cafeterias, restaurants and parks it's very peaceful and relaxing space.

Popular amenities for San Antonio holiday rentals

  1. Airbnb
  2. Colombia
  3. Valle del Cauca
  4. Cali
  5. San Antonio