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Holiday rentals in San Antonio

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Top-rated holiday rentals in San Antonio

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Top guest favourite
An open living area features high ceilings and a striking wooden staircase leading to the upper level. Below, a well-equipped kitchen is arranged with modern bar stools, while a cozy seating area is accentuated by a patterned rug and a decorative plant nearby.
Home in San Cayetano
5 out of 5 average rating, 49 reviews

Colonial House | Historic Center | Cristo Rey View

Welcome to La Casa de Río! A colonial refuge where warm light embraces and the tropical breathes in every corner. In December, Cali wakes up magical: sweet breeze, bright colors and nights that beat to the rhythm of salsa. If you want to live an authentic Caleña experience — culture, flavor, rhythm and human warmth — this is the place. We are in the heart of the Historic Center, within walking distance of restaurants, cafes, and salsa bars. Here you'll find premium rest and a perfect home for up to 6 travelers.

Guest favourite
Flat in El Peñol
4.96 out of 5 average rating, 146 reviews

El Peñon Penthouse - Private Terrace and Cool View

🌴 EXSTR APARTMENT • Brisas del Peñón 401 Stylish 2 bedroom, 2 bathroom penthouse with beautiful views of Cali’s iconic Three Crosses. Enjoy fast 300 Mb Wi-Fi, two workstations (one with electric desk + monitor), SmartTVs, A/C in bedrooms, and noise-reducing windows in the master bedroom. The private terrace features outdoor dining, a BBQ, and a small kitchen — perfect for soaking in Cali’s warm evenings. Located on quiet tree-lined street, steps from Krost bakery and all the best of El Peñon.

Guest favourite
A staircase with black metal steps leads upward, set against a backdrop of exposed brick wall. Natural light flows through large wooden windows with bars, illuminating a decorative plant in a woven basket and a glass bottle on the floor.
Flat in San Antonio
4.89 out of 5 average rating, 64 reviews

Cozy+Unique Loft/Touch of Nature/High Speed WiFi

*BRAND NEW* rustic yet luxurious & modern loft located in San Antonio. Walking distance from Cali's best restaurants, top bars/night clubs! Centrally located in Cali's famous artistic & colonial neighborhood of San Antonio, this chic loft comes equipped with everything you need for a comfortable stay. Full kitchen, queen sized beds, workspace, AC, washer, Smart TV, & more! If you are looking for a true cultural urban experience, with all of the amenities & comfort, then this is your place.

Guest favourite
An open living area features a modern kitchen island with a cooktop, surrounded by wicker chairs and natural light from large panoramic windows. Exposed wooden beams add character to the space, complemented by decorative elements like a wall sculpture and pendant lamps.
Flat in San Antonio
4.96 out of 5 average rating, 27 reviews

Panoramic Suite Overlooking Colonial Cali

Magical View Suite – Colonial Design in San Antonio Experience the soul of Cali from this cozy suite with an unforgettable view In the historic heart of San Antonio, just steps from Hotel Colina, the space blends colonial charm, local art, and a serene atmosphere designed for rest and inspiration Perfect for travelers seeking history, culture, and gastronomy without giving up modern comforts: a fully equipped kitchen, hot water, reliable Wi-Fi, and a postcard-perfect view from the window

Superhost
A modern living area features a comfortable sectional sofa and an oversized ottoman on a plush area rug. Natural light filters through the window blinds, complemented by warm lighting along the walls. A dining bar with three stylish stools creates a versatile space for meals or work.
Flat in San Antonio
4.8 out of 5 average rating, 107 reviews

Beautiful apartment in El Peñon

Luxury apartment located in the exclusive El Peñón neighborhood, the heart of the traditional hotel area of western Cali. Surrounded by a variety of restaurants, bars, nightclubs and cultural areas, close to emblematic sites such as the La Tertulia Museum, the Obelisk, the Cali Zoo, the Cerro de las Tres Cruces, the Gato del Río, the Bulevar del Río, San Antonio and Granada. Perfect for those looking for comfort, style and an unbeatable location to enjoy and explore the city.

Top guest favourite
Flat in San Antonio
4.96 out of 5 average rating, 168 reviews

OM Studio Rooftop at San Antonio - Cali.

Om Studio Rooftop es un lugar para disfrutar de la tranquilidad y del ambiente que tiene. Deléitate con la brisa que baja de las montañas y el canto de los loros al atardecer, acompáñalo con una copa de vino, complácete con una taza de café al despertar, toma una ducha al aire libre y gózate el sol en la terraza en las mañanas. En las noches aprovecha todo lo que tiene el barrio San Antonio para darte. Un espacio único en el corazón de la sucursal del cielo.

Guest favourite
A spacious loft is displayed with an open layout featuring a modern kitchen that transitions into a cozy living area. Large windows provide a panoramic view of the city, while plants add a touch of greenery. The sleeping area is separated by stylish glass panels.
Flat in Santa Isabel
4.94 out of 5 average rating, 84 reviews

H603 Private Jacuzzi | Balcony with Panoramic Views |

** EXCLUSIVE UNIT WITHOUT AIRBNB SERVICE FEES ** Located in the quiet Cristales neighborhood of Cali, this 48m² loft with a private Jacuzzi and an impressive view of Cali, perfect for up to 4 people, is fully equipped for your comfort. The building has amenities such as: coworking, gym, jacuzzis, picnic area, outdoor cinema, and more. Just minutes from Parque del Perro, it combines tranquility, modernity, and comfort in a perfect setting for your stay!

Guest favourite
A terrace showcases a spacious seating arrangement under a large umbrella, featuring two stylish chairs and a coffee table. Lush greenery lines the area, while a view of the city skyline and neighboring buildings is visible in the background.
Serviced apartment in Juanambu
4.87 out of 5 average rating, 146 reviews

Apartamento boutique con terraza y jacuzzi privado

IG @bestairbnbcali (videos) A 7 minutos del centro de la ciudad encuentras este amplio apartamento con diseño nórdico en la mejor ubicación de la ciudad en el barrio centenario/granada cercano a todos los sitios turísticos, tiene terraza con vistas al oeste de Cali y al cerro de las tres cruces, Jacuzzi privado y pantalla de TV gigante, a una cuadra el mall centenario, cerca de bares y restaurantes. Por favor leer las reglas antes de reservar

Guest favourite
A bright living area features a modern sofa and two stylish chairs surrounding a coffee table. Large glass doors offer views of the private pool and the lush green surroundings. Natural light fills the space, creating an inviting and relaxing ambiance.
Villa in Granada
4.83 out of 5 average rating, 178 reviews

Boutique duplex with private pool and cinema

In the Granada neighborhood, 7 minutes from downtown, you will find this charming country house with an excellent location, close to the tourist sites. 1 block from Starbucks, 3 minutes from bars and restaurants, 5 minutes from a mall. The house is rustic, has a private pool and shares the main entrance with another house, both totally independent, we recommend reading the rules before booking. @bestairbnbcali to watch video

Top guest favourite
Flat in San Cayetano
4.98 out of 5 average rating, 46 reviews

Chic Apartment with Private Terrace in San Antonio

Welcome to Cali’s historic San Antonio district. This early-1900s home was thoughtfully restored into a modern, chic condo in 2023. Located in a private 5-unit building, it offers comfort and character just steps from cafés, galleries, and local cuisine. Feel the Cali breeze, walk to top salsa spots, and experience the city like a local. Your Cali-born host is happy to assist in English or Spanish.

Guest favourite
An open-plan living space features a dining table with four chairs adjacent to a modern kitchen. A comfortable sofa is positioned nearby, and large sliding glass doors showcase outdoor greenery. Warm lighting creates a cozy atmosphere, complemented by decorative elements like natural fibers.
Flat in Juanambu
4.93 out of 5 average rating, 120 reviews

IN105 Luxury Oasis | Private Jacuzzi | 350mb WIFI

** EXCLUSIVE UNIT WITH NO AIRBNB SERVICE FEE ** Welcome to our luxurious loft in Cali, inspired by nature. With 44m², a private outdoor Jacuzzi and space for 4 people, it is a contemporary oasis. Living room, dining room, and equipped kitchen offer comfort and style. A private room and full bathroom guarantee a restful night's sleep. Unbeatable location near tourist spots.

Guest favourite
Flat in San Antonio
4.91 out of 5 average rating, 118 reviews

Exclusive Duplex Apartment

Welcome to our newly renovated duplex apartment in the heart of San Antonio! Embrace the latest design trends in this luxurious space where comfort meets style. Enjoy the vibrant atmosphere of the city right at your doorstep. Feel at home as you indulge in modern amenities and soak in the energy of this bustling neighborhood. Your perfect urban getaway awaits!

Popular amenities for San Antonio holiday rentals

  1. Airbnb
  2. Colombia
  3. Valle del Cauca
  4. Cali
  5. San Antonio