
House holiday rentals in Santee
Find and book unique houses on Airbnb
Top-rated house rentals in Santee
Guests agree: these houses are highly rated for location, cleanliness and more.

Mid-Century Modern and Contemporary House
Kick back and relax in this calm, stylish space. 3 bedroom, 2 bath house. The master suite has a soaking cast iron tub with complementary bath essentials, oversized walk in shower and a double sink vanity. There are wall mounted TV's in the master bedroom, guest bedroom, living room and sunroom. The open concept Kitchen, Living room and dining room is great for entertaining! The house has in-ceiling speakers throughout and in the pool area. The pool and spa heats. There is also a WFH work space

XTRA 10% OFF until Nov: Pool, outdoor fire pits, c
Find your family's dream spot in San Diego! Our cozy house sits on a quiet hill, offering privacy and amazing sunset views. Dive into our pool year-round (heating at an additional cost), roast marshmallows by the fire, and cook up fun meals together. With 3 bedrooms and 2 bathrooms, it’s perfect for families, accommodating up to 9 guests. Plus, we're close to all the best attractions. Want a vacation you'll always remember? Send us a message to make it happen! 🌅🏠 We have 3 comfy beds that can

2 Bed Hidden Oasis | Garden, Laundry, Parking
Capture the essence of San Diego in our Hidden King Suite with Garden hosted by Ethos Vacation Homes. The peaceful property features elite comfort for up to 4 guests with beautiful outdoors and garden, off-street parking, A/C and heating, FREE laundry, comfortable king and queen size beds, plenty of sheets and towels, a large HDTV, Netflix, Max, Hulu, Showtime, Disney+, Apple+, and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!

SD Casita Sleeps 6 - Morey from Prieto Surf Ranch
The Morey de Prieto Surf Ranch is truly awesome! Reserve your stay in this 2 Bed/1 Bath 650 sq. ft. casita for six. Home includes a kitchen with many amenities including a GE electric cooktop, refrigerator, microwave and air fryer, rice cooker, Kitchenaid mixer, mixer for drinks, sink with prep trays, Moen faucet fixtures, gorgeous shower, Krups coffee maker, 50" smart TV equipped with WiFi and NetFlix, mountain views, workspace and a sofabed. How about a large deck with fire pit and BBQ?

Sunny & Spacious 3BR Retreat w/ Parking & A/C
Centrally located in La Mesa is this newly refurbished home ideal for business or pleasure with all of life’s little luxuries waiting for you to enjoy. The home features open concept living with a gourmet kitchen, a chic dining space, 3 beautiful bedrooms, 2 modern bathrooms and an expansive yard with an outdoor lounge. Walk 10 mins to Grossman Center with a Target, restaurants, cafes, a cinema & Walmart or drive to the heart of San Diego and all its attractions just 20 mins from your door.

The Glass House - A Nature Retreat
Enjoy a unique retreat; 180 degrees of views from inside the home. Nestled at the end of a private road, our place is nearby great hiking and countryside wineries. The Glass House provides a magical space and nature retreat where individuals, couples, families and friends can gather together to re-connect with nature, each other, and themselves. The breathtaking mountain top views, the huge deck, hot tub, fireplace, and the open concept living space is unbeatable for the perfect getaway.

Bright and spacious home with views, pool & spa.
This beautiful and recently remodeled, open-floor plan home is conveniently located directly across from Cowles Mountain, one of San Diego's most visited hiking trails. Each bedroom has its own full bathroom. Perfectly located for the outdoorsy family. Tons of hiking and mountain bike trails are just across the street. Only 15 min. away from beaches, zoo, & Sea World. Gaslamp/Downtown is only 20 min. by car. After a day of exploring, come home to a newly-built, salt-water pool and spa.

Cottage in the Garden! New! Modern!
COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub
Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our studio is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions

(Relist!) Relax at a Stunning 1931 Historic Tudor!
Come & enjoy our 1931 historic tudor home! Beautifully rebuilt within the last 2 years. This house has a huge front lawn and space to roam. Enjoy the serenity this large property has to offer. Three peaceful patios to enjoy your morning coffee. The kitchen has an 48-inch 1950’s oven for the chef in the family. Bay windows, arched entryways and original light fixtures make this such a charming place to stay. Centrally located to enjoy everything San Diego & La Mesa has to offer.

Peaceful Casita | Firepit • Near SDSU
Welcome to our cozy home, perfect for couples visiting the area. It's also a great spot for SDSU parents visiting their kids. Conveniently close to the campus but far enough to enjoy some peace and quiet. If you enjoy this listing, click the heart icon ❤ in the top-right corner to bookmark it for easy access! Minutes from key attractions: ★ 6 min to SDSU/Viejas Arena ★ 14 min to Balboa Park ★ 17 min to Downtown SD (Gaslamp) ★ 19 min to San Diego Zoo ★ 21 min to the Airport

Beautiful 3,000 Sq Ft Tropical Oasis
Beautiful 4 Bedroom, 2 1/2 Bath Family Home Located in Tranquil Fletcher Hills. This 3,000 sq. ft. Home is Perfect for large families who wish to Relax in a Peaceful Setting. 24-hour self check-in keypad after 4pm and check-out at 11AM. Host does not allow parties/events. This is NOT a Party House! This home is located in a quiet residential neighborhood, Guests who do not respect this will be asked to leave.
Popular amenities for house rentals in Santee
House rentals with a pool

The Queen House

Luxury Resort: Game Room/VolleyBall/Pool/Hot Tub!

Flamingo Sunset House: Sleeps 10: Pool + Hot Tub

Updated TownHome, Great Location, Fantastic Views

Custom Guesthouse, Balboa Park/Zoo/Hillcrest& pool

Designer Luxury Rental With Pool

Modern Hilltop Home: Roomy, Views, Family-Friendly

Luxe Home w. Serene Backyard Spa
Weekly house rentals

Tiny Home with a View

Hot tub, salt water pool, peaceful family oasis

Airbnb Luxe: Designer Pool, Fitness and Office

A Perfect Pet Friendly Getaway.

Discover La Mesa: Your Perfect Cozy Base

Cozy quiet getaway, great mattress (1-br)

Charming Cozy Studio Centrally Located

Heated Pool*, fire pit hot tub, views, Hiking
Private house rentals

Spacious Home with Large Yard and Mountain Views

A Walk in the Clouds: Stunning Views & Game Room!

Lakeside Deluxe 1-Bedroom

XLarge Artist's Retreat w/private patio/parking

Modern, Private, & Stylish Home

ModernCoastal I View I Pool ITub

Entire house, fenced yard, and driveway

Private House in the Hills, Pool, Pickleball court
When is the best time to visit Santee?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $174 SGD | $159 SGD | $129 SGD | $195 SGD | $206 SGD | $165 SGD | $282 SGD | $247 SGD | $224 SGD | $148 SGD | $293 SGD | $283 SGD |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Quick stats about house rentals in Santee

Total holiday rentals
Explore 50 holiday rentals in Santee

Nightly prices starting at
Santee holiday rentals start at $39 SGD per night before taxes and fees

Verified guest reviews
Over 1,390 verified reviews to help you choose

Family-friendly holiday rentals
30 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 10 rentals that welcome pets

Holiday rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wifi availability
50 of Santee holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Santee rentals

4.9 Average rating
Santee stays are highly rated by guests – averaging 4.9 out of 5!
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- Family-friendly rentals Santee
- Rentals with a washing machine and dryer Santee
- Rentals with outdoor seating Santee
- Rentals with a hot tub Santee
- Rentals with a patio Santee
- Pet-friendly rentals Santee
- Rentals with a fireplace Santee
- Lakehouse rentals Santee
- Rentals with a firepit Santee
- Rentals with pools Santee
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