
House holiday rentals in Santee
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Top-rated house rentals in Santee
Guests agree: these houses are highly rated for location, cleanliness and more.

2 Bed Hidden Oasis | Garden, Laundry, Parking
Capture the essence of San Diego in our Hidden King Suite with Garden hosted by Ethos Vacation Homes. The peaceful property features elite comfort for up to 4 guests with beautiful outdoors and garden, off-street parking, A/C and heating, FREE laundry, comfortable king and queen size beds, plenty of sheets and towels, a large HDTV, Netflix, Max, Hulu, Showtime, Disney+, Apple+, and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!

Morey de Prieto Surf Ranch Sleeps 6 House
The Morey de Prieto Surf Ranch is truly awesome! Reserve your stay in this 2 Bed/1 Bath 650 sq. ft. casita for six. Home includes a kitchen with many amenities including a GE electric cooktop, refrigerator, microwave and air fryer, rice cooker, Kitchenaid mixer, mixer for drinks, sink with prep trays, Moen faucet fixtures, gorgeous shower, Krups coffee maker, 50" smart TV equipped with WiFi and NetFlix, mountain views, workspace and a sofabed. How about a large deck with fire pit and BBQ?

Sunny & Spacious 3BR Retreat w/ Parking & A/C
Centrally located in La Mesa is this newly refurbished home ideal for business or pleasure with all of life’s little luxuries waiting for you to enjoy. The home features open concept living with a gourmet kitchen, a chic dining space, 3 beautiful bedrooms, 2 modern bathrooms and an expansive yard with an outdoor lounge. Walk 10 mins to Grossman Center with a Target, restaurants, cafes, a cinema & Walmart or drive to the heart of San Diego and all its attractions just 20 mins from your door.

The Glass House - A Nature Retreat
Enjoy a unique retreat; 180 degrees of views from inside the home. Nestled at the end of a private road, our place is nearby great hiking and countryside wineries. The Glass House provides a magical space and nature retreat where individuals, couples, families and friends can gather together to re-connect with nature, each other, and themselves. The breathtaking mountain top views, the huge deck, hot tub, fireplace, and the open concept living space is unbeatable for the perfect getaway.

Bright and spacious home with views, pool & spa.
This beautiful and recently remodeled, open-floor plan home is conveniently located directly across from Cowles Mountain, one of San Diego's most visited hiking trails. Each bedroom has its own full bathroom. Perfectly located for the outdoorsy family. Tons of hiking and mountain bike trails are just across the street. Only 15 min. away from beaches, zoo, & Sea World. Gaslamp/Downtown is only 20 min. by car. After a day of exploring, come home to a newly-built, salt-water pool and spa.

Cottage in the Garden! New! Modern!
COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

Zen Retreat: 3-Bedroom Oasis near La Mesa Village
Relax in this charming 3-bedroom, 1-bathroom home located just 1 mile from the heart of Historic Downtown La Mesa Village. Nestled in a quiet, central neighborhood, this cozy retreat offers easy access to major freeways, top-rated restaurants, and the local trolley line making it a breeze to explore the best of San Diego. Within 10 to 15 miles, you’ll find yourself in iconic destinations like Downtown San Diego, Balboa Park, Coronado Island, scenic beaches, and beautiful mountain trails.

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub
Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our studio is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions

(Relist!) Relax at a Stunning 1931 Historic Tudor!
Come & enjoy our 1931 historic tudor home! Beautifully rebuilt within the last 2 years. This house has a huge front lawn and space to roam. Enjoy the serenity this large property has to offer. Three peaceful patios to enjoy your morning coffee. The kitchen has an 48-inch 1950’s oven for the chef in the family. Bay windows, arched entryways and original light fixtures make this such a charming place to stay. Centrally located to enjoy everything San Diego & La Mesa has to offer.

Peaceful Casita | Firepit • Near SDSU
Welcome to our cozy home, perfect for couples visiting the area. It's also a great spot for SDSU parents visiting their kids. Conveniently close to the campus but far enough to enjoy some peace and quiet. If you enjoy this listing, click the heart icon ❤ in the top-right corner to bookmark it for easy access! Minutes from key attractions: ★ 6 min to SDSU/Viejas Arena ★ 14 min to Balboa Park ★ 17 min to Downtown SD (Gaslamp) ★ 19 min to San Diego Zoo ★ 21 min to the Airport

ROMANTIC AND SPACIOUS JACUZZI SUITE!
Completely private sanctuary--no shared spaces--and it has a private entrance. Enjoy stunning sunrises and sunsets from your two private balconies. Unwind in the jacuzzi. This suite is provided with everything you need to feel at home, such as plush mattresses and linens, a kitchenette with microwave, coffee maker, mini-frig, toaster, and necessities including silverware and dishes, and in the bathroom, an iron and hair dryer.

Spacious & Fun | 5br, 4.5ba | Hot Tub | Views
Experience sunny San Diego from this 5 bedroom, 4.5 bathroom foothill home. Wake up to panoramic views of the surrounding hillsides and gather in the spacious living and dining rooms. The home is conveniently located just 15-20 minutes from San Diego's famous beaches and top attractions. After a day of exploration, unwind in the backyard area featuring a hot tub, fire pit, pool table, and life-sized chessboard.
Popular amenities for house rentals in Santee
House rentals with a pool

The Queen House

Lionhead - Private Boutique Home

Mid-Century Modern and Contemporary House

Custom Guesthouse, Balboa Park/Zoo/Hillcrest& pool

Updated TownHome, Great Location, Fantastic Views

Luxe Home w. Serene Backyard Spa

Upscale Resort House /Views, Saltwater Pool/Spa !

Luxe Point Loma Oasis w/ Pool, Spa & Fire Pit
Weekly house rentals

Tiny Home with a View

Family Fun Getaway | 3BR + Games & BBQ Patio

Airbnb Luxe: The Perfect Blend of Access & Escape

A Perfect Pet Friendly Getaway.

Discover La Mesa: Your Perfect Cozy Base

Jamul Hacienda | Couples Retreat | Pool & Views!

HUGE 5BR Family Retreat! Backyard & Patio Lounge

Luxury Hilltop Getaway • Scenic Views
Private house rentals

Luxury 4 BR w/ Serene Lake Views

Serenity in San Diego

Farmhouse on Sunny Outdoor Dining area 20min to SD

Bright & Quiet 4BR Family Home

Garden Retreat in North Park.

Cozy quiet getaway, great mattress (1-br)

ModernCoastal I View I Pool ITub

Studio In Home with Private Entry
When is the best time to visit Santee?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $175 SGD | $161 SGD | $130 SGD | $197 SGD | $208 SGD | $166 SGD | $284 SGD | $249 SGD | $226 SGD | $149 SGD | $296 SGD | $286 SGD |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Quick stats about house rentals in Santee

Total holiday rentals
Explore 50 holiday rentals in Santee

Nightly prices starting at
Santee holiday rentals start at $39 SGD per night before taxes and fees

Verified guest reviews
Over 1,390 verified reviews to help you choose

Family-friendly holiday rentals
30 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 10 rentals that welcome pets

Holiday rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wifi availability
50 of Santee holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Santee rentals

4.9 Average rating
Santee stays are highly rated by guests – averaging 4.9 out of 5!
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- Rentals with a patio Santee
- Rentals with a firepit Santee
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- Lakehouse rentals Santee
- Family-friendly rentals Santee
- Rentals with pools Santee
- Rentals with a hot tub Santee
- Pet-friendly rentals Santee
- Rentals with a fireplace Santee
- Rentals with a washing machine and dryer Santee
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