Boutique hotels in Santo Domingo

Find and book unique boutique hotels on Airbnb

Top-rated boutique hotels in Santo Domingo

Guests agree: these boutique hotels are highly rated for location, cleanliness and more.

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Guest favourite

A spacious room is illuminated by natural light, featuring a comfortable queen bed with crisp linens and a soft, patterned throw. A seating area with a modern sofa is visible, along with a flat-screen TV mounted on the wall. Large glass doors open to a balcony.

Hotel room in Ciudad Colonial

4.99 out of 5 average rating, 178 reviews

Loft 201 · Zona Colonial · Balcony + Breakfast

Loft 201 at Casa Adefra, located on El Conde Street in the heart of the Colonial Zone. Walk easily to the main attractions, restaurants, and cafés. This loft features a private balcony overlooking El Conde Street. Room features: -Keyless room access -Private bathroom -Smart TV with local cable and Netflix -In-room safe -Air conditioning -Electric water heater -Kitchenette with two-burner electric stove -Free high-speed Wi-Fi Daily housekeeping and breakfast included Front desk available 24/7

Guest favourite

A living area is showcased with a light-colored sofa and a round dining table with wooden chairs. A decorative wall highlights natural elements and patterns. A kitchenette is visible, equipped with modern appliances and under-cabinet lighting, enhancing the room's functionality.

Hotel room in Ciudad Colonial

4.95 out of 5 average rating, 111 reviews

Loft 103 · Zona Colonial · King Bed + Breakfast

Loft 103 at Casa Adefra, located on El Conde Street in the heart of the Colonial Zone. Walk easily to the main attractions, restaurants, and cafés. This loft features a comfortable living room (no balcony). Room features: -Keyless room access -Private bathroom -Smart TV with local cable and Netflix -In-room safe -Air conditioning -Electric water heater -Kitchenette with two-burner electric stove -Free high-speed Wi-Fi Daily housekeeping and breakfast included. Front desk available 24/7.

Guest favourite

A cozy living area features a light-colored sofa adorned with colorful cushions. Nearby, a small wooden dining table is positioned next to a potted plant. The walls exhibit a subtle pastel hue, complementing decorative woven elements and maintaining a warm ambiance.

Hotel room in Ciudad Colonial

4.98 out of 5 average rating, 96 reviews

Loft 203 · Zona Colonial · King bed + Breakfast

Loft 203 at Casa Adefra, located on El Conde Street in the heart of the Colonial Zone. Walk easily to the main attractions, restaurants, and cafés. This loft features a comfortable living room (no balcony). Room features: -Keyless room access -Private bathroom -Smart TV with local cable and Netflix -In-room safe -Air conditioning -Electric water heater -Kitchenette with two-burner electric stove -Free high-speed Wi-Fi Daily housekeeping and breakfast included. Front desk available 24/7.

Top guest favourite

A spacious suite is showcased, featuring a king-sized bed with soft linens. A flat-screen TV is mounted on the wall opposite the bed, and large glass doors lead to a balcony area. Natural light fills the room through window treatments, enhancing the cozy atmosphere.

Hotel room in Ciudad Colonial

5.0 out of 5 average rating, 86 reviews

Loft 204 · Zona Colonial · Balcony + Breakfast

Loft 204 at Casa Adefra, located on El Conde Street in the heart of the Colonial Zone. Walk easily to the main attractions, restaurants, and cafés. This loft features a balcony overlooking the terrace. Room features: -Keyless room access -Private bathroom -Smart TV with local cable and Netflix -In-room safe -Air conditioning -Electric water heater -Kitchenette with two-burner electric stove -Free high-speed Wi-Fi Daily housekeeping and breakfast included. Front desk available 24/7.

Top guest favourite

A serene room features a spacious bed adorned with a light green blanket. A large mirror reflects the natural light from the window, and modern fixtures are visible, including a smart TV and a wall-mounted light. A private bathroom entrance is positioned to the right.

Hotel room in Ciudad Colonial

5.0 out of 5 average rating, 51 reviews

Loft 205 · Zona Colonial · Balcony + Breakfast

Loft 205 at Casa Adefra, located on El Conde Street in the heart of the Colonial Zone. Walk easily to the main attractions, restaurants, and cafés. This loft features a balcony overlooking the terrace. Room features: -Keyless room access -Private bathroom -Smart TV with local cable and Netflix -In-room safe -Air conditioning -Electric water heater -Kitchenette with two-burner electric stove -Free high-speed Wi-Fi Daily housekeeping and breakfast included. Front desk available 24/7.

Hotel room in Ciudad Colonial

4.1 out of 5 average rating, 29 reviews

Stay in the Heart of Colonial Zone • AC • WiFi

Located in the iconic Colonial Zone, our hotel combines the elegance of the past with the comforts of the present. Enjoy comfortable accommodation with spacious rooms and traditional décor, plus modern amenities such as high-speed Wi-Fi and air conditioning. Just a few minutes' walk away, you can explore historic sites, enjoy local cuisine, and discover the city's vibrant nightlife.

Hotel room in Villa Altagracia

Golden Hills Eco Hotel | Swim-Up Room

Discover a unique space where nature and comfort come together. Our eco-hotel provides room service for all our guests at no extra cost. You can find a wide variety of food and beverages available for purchase at our Ladera restaurant, Sabor a Montana. Perfect for those seeking a balance between location, comfort, and connection with nature.

Superhost

A spacious sleeping area features a large bed with a white quilt and teal accents. Two bedside tables with lamps flank the bed, and a light-toned dresser is positioned nearby. Natural light enters through a glass door, complemented by patterned tile flooring.

Hotel room in Ciudad Colonial

4.83 out of 5 average rating, 6 reviews

Brisas Colonial 103

Enjoy the simplicity of this quiet and central accommodation. On the historic El Conde street, with access to countless restaurants, museums, close to the city's esplanade. Good for resting and sightseeing.

A charming building features a balcony adorned with flags from various countries. Bright red bougainvillea blooms in the foreground, adding contrast to the historic architecture. The scene is set against a dramatic sky, highlighting the vibrant colors of the flowers and the intricate details of the building.

Hotel room in Ciudad Colonial

4.52 out of 5 average rating, 52 reviews

Cozy Luxury Studio, Colonial Zone, Free Breakfast

This charming and exclusive place to stay doesn't overlook any detail. Perfect for couples and excellent decor. BREAKFAST INCLUDED. WE ACCEPT PETS. ADDITIONAL COST OF $20 PER NIGHT, PAID AT CHECK-IN

A bright room is furnished with a spacious bed dressed in white linens and accented with green and brown throw pillows. A sleek black sofa and a small desk are positioned by large windows, providing ample natural light and an open view.

Hotel room in Ciudad Universitaria

4.0 out of 5 average rating, 14 reviews

Malecon hotel

Boutique hotel on the strip of Santo Domingo( el malecon )Ocean view and all major hotel and franchises All transportation in from of the hotel 5 minutes drive to zona colonia and beach (guivia)