
Places to stay near Six Mile Cypress Slough Preserve
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Top-rated holiday rentals near Six Mile Cypress Slough Preserve
Guests agree: these stays are highly rated for location, cleanliness and more.

Private farmhouse stay at Dim Jandy Ranch.
Take it easy at this unique and tranquil getaway. A beautifully appointed bed and bath in a separate building from the house. We have goats, donkeys and chickens and a Highland cow, all super friendly. Sit and relax on your private, beautiful lanai or any of our farm tables placed around the property. Join us as we feed the animals. Or even join in one of our Goat Yoga classes! We're easily located close to I-75, airports, shopping, beaches, downtown. Perfect for couples or solo travelers.

LUX Villa w/ Private Salt Water Pool, Lanai, Canal
Are you looking to swim, relax outdoors, fish and take in beautiful sunsets on a wide gulf access canal? If so you will fall in love with this stunning newly constructed custom built home! The 2750 square foot home is bright & airy with two main bedroom on-suites & a separate family wing! The gourmet kitchen, dining room & great room open via large sliders to the lanai & pool w/ views of the canal in much desired SW Cape! Beach inspired villa! Large captains walk & Tiki! Check out our reviews!

Hidden Gem with Pool. Perfect for Family Getaway
Welcome to Your Serene Florida Escape, where comfort meets competitive daily rate. We also offer special weekly and monthly rate! Your home away from home is equipped with high-speed Wi-Fi, smart TV, free parking, and more. This inviting retreat features a modern kitchen, spacious living area, and a tranquil backyard with a heated pool. Perfect for families, couples, or solo travelers. You can relax by the pool, enjoy a bonfire with your loved ones, or conveniently explore nearby attractions.

Sleep over the water- Boathouse with Private Dock
This 1920s boathouse offers a once-in-a-lifetime stay directly over Whiskey Creek, where the gentle sound of water beneath your feet lulls you to sleep. With a private entrance, dock and waterfront views, this isn't just a room--it is an unforgettable Florida experience. This boathouse has been ungraded with all modern conveniences and is centrally located close to downtown, restaurants and shopping. Sip your morning coffee on the dock as herons and bald eagles glide across the creek.

Intervillas Florida - Villa The View
The View – Luxury Waterfront Villa with Infinity Pool & Sunset Views The View welcomes you from the very first moment with breathtaking, wide lake views and spectacular sunsets that turn every day into an unforgettable experience. Perfectly located in a quiet and highly desirable position on one of the lower 8-Lakes, the villa offers direct boat access, allowing you to reach the River and the Gulf of Mexico in a short and scenic ride – ideal for boating enthusiasts and water lovers.

Blue Beach Bungalow
3 large bedrooms (3 king sized beds) with TV in everyroom, plus a full den, laundry room, HEATED pool and the house has its own beach with an in-ground fire pit that seats 12, lounge chairs, and sunset views! Walking distance to shopping centers, great restaurants, 20 minutes to RSW Airport and Fort Myers' white-sand beaches, perfect for a romantic get-away and 10 minutes from downtown Fort Myers Completely remodeled in July of 2021 with brand new appliances electronics,

Modern City Loft in Downtown River District
Welcome to Gun-Loft, a custom-designed modern sanctuary in the Downtown River District. This expansive 3500 square foot city loft is tailored for those seeking to embrace the cosmopolitan lifestyle, with the perfect blend of urban luxury and cultural richness. Whether it's a leisurely stroll to the Edison Ford Home, an exciting night out, or a culinary adventure in the restaurants nearby, Gun-Loft offers an unparalleled experience in the city's most coveted location.

Whole cozy house
Entire cozy house just for you friends and family. Perfect to spend a pleasant and relaxed moment. If you plan to have a party or event, this place is NOT for you. The neighbors are very strict in terms of noise and large groups of people. Well maintained house. CLEAN POOL BUT NOT HEATED. Walk in to a living area and separated dining. 20 minutes to airport, 25 minutes to the beach, fine dining and entertainment. For a virtual tour, click on the cover photo twice.

Dive into Luxury: Stunning Tropical Home & Pool
Escape to a tropical paradise in this stunning 1952 midcentury modern home, perfectly located in the heart of historical McGregor Boulevard - home to the famous palm trees planted by Thomas Edison. Indulge in delicious meals at local restaurants like McGregor Cafe and McGregor Pizza, or tee off at the nearby public golf course. And if you're looking to hit the beach or explore downtown, both are just a short drive away.

Coastal Modern Retreat with Heated Pool and Spa
Retreat to paradise in this extra clean and beautifully renovated home centralized to all major Southwest Florida attractions. Splash and play in your private, year-round heated pool or relax and unwind in the bubbles of the jacuzzi. Heating included in price! Less than a 10 minute drive gets you to RSW airport, tons of excellent restaurants, three supermarkets and 4 major shopping malls.

17th Floor Riverfront • Downtown • Pool & Gym
🌅 Ember Horizon · 17th Floor Riverfront Wake up to panoramic river views from the 17th floor of a modern downtown high-rise. This 2BR/2BA features floor-to-ceiling windows, two private en-suite bedrooms, and a fully equipped kitchen. Enjoy the building's pool, 24-hr gym, secure access, and free garage parking — all just steps from Fort Myers' best restaurants, bars, and nightlife.

Luxury Villa: Pool, Hot Tub And Amazing Lake View
Escape to a private waterfront paradise on the famous Eight Lakes! This luxurious home offers spectacular sunset views from your private infinity pool and hot tub. Perfect for a relaxing retreat, it features seamless indoor-outdoor living, a gourmet kitchen, and high-end amenities. Ideal for couples or small groups seeking an unforgettable getaway.
Popular amenities for holiday rentals near Six Mile Cypress Slough Preserve
Other top sights near Six Mile Cypress Slough Preserve
Apartment rentals with wifi

Lovely Gulf Access/Kayak, Beach, Tiki Bar & Grill.

Rare walkout condo on Sanibel beach

Beachfront fully equipped apartment

Luxury Gulf View Condo + Steps to the Beach

Beachfront Escape w/ Sunset Views, Pool & Hot Tub

Ark - Captiva Beach Villas

Sea Salt Beach Front Condo

100+ 5 Star Reviews and Right on The Beach!
Family-friendly house rentals

Luxury Riverfront Retreat • Pool & Spa • 60ft Dock

Entertainers Paradise w/ HTD Pool & Putting Green

Swimsational Golf views

Family Oasis | Heated Pool + Beach Gear, Kid Ready

Mini Golf • Heated Pool • Near Beach Prime

Cape Escape | Hot Tub | Heated Pool | Game Room

Luxurious central POOL home, KID&PET friendly

Fort Myers Family retreat
Apartment rentals with air conditioning

Twin Palm - Sunny Days & Breezy Nights

Charming King Studio · Private Patio · Boca Grande

Blackstone Villa

Beach/Sunset Bay/Sunrise Relax/Island Living

Modern Room • Private • Outdoor Space

Villa San Carlos Park

Vacation in Paradise

Downtown Studio: Full Kitchen, King Bed, & Pool 6
Other great holiday rentals near Six Mile Cypress Slough Preserve

AquaLux Smart Home

Luxury Waterfront Escape - Private Pool & Jacuzzi

Sunnyside - Pool, Hot Tub& Direct access to River

Riverfront Riviera Outdoor TV's/Hotub/Tanning Deck

Villa Sunset Serenade II

Waterfront Estate With Heated Infinity Pool

3 BR Heated Pool House with Boat Lift

TikiTime Tropical Riverfront Retreat
Destinations to explore
- Naples Beach
- Captiva Island
- Manasota Key Beach
- Englewood Beach
- Lovers Key Beach
- Tigertail Beach
- Florida Gulf Coast University
- Stump Pass Beach State Park
- Blind Pass Beach
- Bonita National Golf & Country Club
- Bowman's Beach
- Barefoot beach Bonita Springs,FL
- Boca Grande Pass
- Jetblue Park
- Montura Ranch Estates
- The Naples Pier
- Clam Pass Park
- Bunche Beach
- Edison & Ford Winter Estates
- Yacht Club Public Beach
- Ave Maria University
- Coral Oaks Golf Course
- Delnor-Wiggins Pass State Park
- Lovers Key State Park





