Places to stay near Buffalo Museum of Science

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Top-rated holiday rentals near Buffalo Museum of Science

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
A spacious kitchen is highlighted by light blue walls and granite countertops. Wooden shelves display items on one side, while a breakfast nook with large windows invites natural light. Three wooden stools are positioned at the counter for casual seating.
Home in Buffalo
4.88 out of 5 average rating, 152 reviews

Cozy 4BR Buffalo Home | Near Parks | Save 5% week

Historic 4BR Retreat | 7 Mins to Downtown! Relax in this 2,200 sq ft home blending historic character with a comfortable open layout. Features beautiful century-old woodwork and a fully equipped kitchen with everything you need. Highlights: • Sleeps 8: 4 roomy upstairs bedrooms. • Work & Relax: Quiet dedicated office + Zen room. • Outdoor Space: Large backyard with a patio & grill. • Great Location: 7 mins to downtown, 15 mins to airport. We're committed to a great stay. Book your getaway today!

Superhost
A monochromatic living area is showcased, featuring a patterned black-and-white sofa paired with minimalist stools and a sleek coffee table. Light fixtures hang from the ceiling, and a glimpse of the kitchen is visible in the background, complemented by clean lines and artistic wall designs.
Flat in Buffalo
4.84 out of 5 average rating, 272 reviews

The 2D Spot!

Buffalo's 1st official 2D Airbnb; all hand painted by local Artists. With ideal proximity to DT Buffalo, Elmwood Village & Allentown, you'll find yourself at the heart of the city's culture. Also just a 25 minute drive to the iconic Niagara Falls. Whether you're a first time visitor to Buffalo or a local seeking a unique escape, The2DSpot invites you to step inside the pages of a comic book. Immerse yourself in a world of imagination & book your stay today! Experience Buffalo like never before.

Guest favourite
The living area features a comfortable gray couch with decorative cushions, a wooden side table with a lamp, and an area rug. An artistic cityscape is displayed on the wall, while a dining area is visible through the archway with a table and chairs.
Flat in Buffalo
4.85 out of 5 average rating, 315 reviews

Historic Apartment Steps Away from Allentown Area

This spacious 1-bedroom apartment is conveniently located in the heart of Allentown. It is fully furnished and includes everything you will need to have a comfortable, enjoyable stay. This is 1 of 3 airbnbs located in a historic multi-unit home. This space is the perfect getaway for couples, business stays, and traveling nurses. It is situated in a quiet residential neighborhood, steps away from Allen St. The front door opens to a small park that was designed by Frederick Law Olmsted in 1887.

Top guest favourite
Home in Buffalo
4.92 out of 5 average rating, 183 reviews

The Italianate: Historic Home w/ Sauna and Firepit

This beautifully restored late-1800s Victorian Italianate home offers a relaxing, centrally located retreat in Buffalo, NY, complete with a private, fenced yard containing a dry heat sauna and fire pit with complimentary firewood. Historic architectural details blend seamlessly with modern updates, including a fully stocked kitchen (coffee included). Located in the heart of Allentown, it’s an ideal stay for luxury family trips and wedding parties seeking comfort, space, and a refined home base.

Guest favourite
A bright and airy loft features a spacious sleeping area with a queen bed, complemented by marble flooring. A gas fireplace creates a cozy focal point, while a desk and seating area provide functionality. Large windows allow natural light to fill the space.
Castle in Buffalo
4.84 out of 5 average rating, 310 reviews

Fireplace Luxury Spa Loft Gym Bball Rooftop EV+

Ideal for extended stays, this stunning luxury loft is located in an architecturally significant building in the heart of Elmwood Village and nearby Allentown. Enjoy access to top-notch amenities, including gym, dedicated work area & indoor basketball court. The loft features a unique layout with spa like amenities, couples shower and wet room, fully equipped gourmet kitchen, elegant marble finishes. Serene sunken living/sleeping area, with queen bed, gas fireplace, 65", standup work desk.

Top guest favourite
A modern kitchen features sleek white cabinetry and a dark countertop. A stainless steel refrigerator and gas stove are visible, alongside a microwave. Natural light enters through nearby windows, illuminating the space. A patterned rug lies on the floor, adding a touch of comfort.
Guest house in Buffalo
4.99 out of 5 average rating, 244 reviews

Hidden Parkside Carriage House near everything.

This beautifully redone 1915 Carriage house that is just 2 blocks from Delaware park , The zoo and the Darwin Martin house. Fully updated with plenty of room to cook and relax. 55in Smart tv and all brand new furniture. If you do not want to drive it is a 2 block walk to the train that can take you right downtown, Canalside or the Keybank Center (Sabres Arena) . Located right off the 33 so minutes to the airport , downtown and about 20 minutes to Niagara Falls and 20 to Highmark Stadium.

Top guest favourite
An open-concept kitchen is equipped with modern appliances, including a refrigerator, oven, and microwave. White cabinets contrast against dark granite countertops. A round dining table with black chairs is centrally positioned, and recessed lighting illuminates the space, enhancing a sense of spaciousness.
Loft in Buffalo
4.93 out of 5 average rating, 730 reviews

LarkinVille Loft (Unit 1)

If this listing is not available please check out my other listings This 1st floor loft features an open concept kitchen & living room with stove, refrigerator & microwave. A queen sleeper sofa & 46" smart TV are in the living room. The bedroom has a king bed, dresser & recliner. Washer & dryer can be found in the bathroom along with a soaker jacuzzi tub. A/C mini splits help cool down the space. This is a mix use property with periment tenants as well as other guest. Noise is typically low

Top guest favourite
A modern living space features a comfortable dark sofa adorned with a bright throw. A compact kitchen with sleek cabinetry and a black stove sits in the background. Natural light enters through large windows, highlighting the warm wooden flooring.
Flat in Buffalo
4.98 out of 5 average rating, 288 reviews

Cozy Carriage House on Elmwood

Beautiful Airbnb inside a historic carriage house. Located directly on Elmwood Avenue but tucked back & secluded for a peaceful stay. Cozy interior with coffee bar included. The cottage’s prime location is within walking distance to many restaurants, bars, cafes, boutique shops, Delaware Park, the AKG and Birchfield Penney art museums, and more. Off-street parking allows easy access to adventure outside of the village with Niagara Falls & the Bills Stadium just a 20-30 min. drive/Uber away!

Top guest favourite
A well-appointed sleeping area features a black metal bed with a plush comforter and several decorative pillows. The space is enhanced by botanical artwork on the walls and a functional work desk with a mini fridge and coffee maker nearby, illuminated by a ceiling fan.
Guest suite in Buffalo
4.99 out of 5 average rating, 273 reviews

Five Points Hideaway

Welcome to 5 Points! Offering a private, hotel room style- 1 bedroom/1 bathroom guest suite attached to a historic home in the heart of the Five Points neighborhood on Buffalo’s Westside. Private entrance. This cozy spot is perfect for an overnight or weekend visit. Mini fridge, microwave and Keurig provided. Just 8 minutes from Downtown and 25 minutes from Niagara Falls. Walking distance to great restaurants and bars. Close to Buff State, AKG, Medical Campus, Convention Center & Arena.

Superhost
A cozy living room is featured, showcasing a grey sectional sofa adorned with colorful pillows. A sleek television stands on a dark media unit, accompanied by a modern floor lamp. Light filters through a nearby window, enhancing the warm tones of the area rug.
Flat in Buffalo
4.86 out of 5 average rating, 523 reviews

Clean, Spacious, Convenient, Comfortable, Historic

- Impeccably decorated - Recently updated - 1st-floor apartment of a - Historic home - Heart of Buffalo - A few minutes to all of Buffalo's favorite spots - Budget conscious Midtown is a distinctly urban and multi-cultural neighborhood that is beginning a renaissance. If you are intimidated by the urban setting, you might be out of your comfort zone. You will see a few vacant houses and might hear a distant ambulance (nearby hospital) in this safe and quiet neighborhood.

Guest favourite
A modern dining area features a round wooden table surrounded by four white chairs. A stylish light fixture hangs above, complemented by green accent walls. The open layout connects to a well-equipped kitchen with white cabinetry and bar seating, illuminated by natural light from surrounding windows.
Flat in Buffalo
4.87 out of 5 average rating, 252 reviews

Five Points Apartment- Upper Unit

Updated Upper Unit Apartment. Great City Location! Walking Distance to Five Points, and Lower West Side Restaurants and Shops. Off Street Parking (when available). In Unit Laundry. WiFi. Pets Allowed ($50 pet fee). Queen Bed and Fold Down Futon. Blocks from D’Youville University and minutes from Buffalo State University! Close to Kleinhans Music Hall, Elmwood Village and Allentown! 10 Min Drive To KeyBank Center - 20 Min Drive To Highmark Stadium - 20 Min Drive To Niagara Falls

Top guest favourite
Cottage in Fort Erie
4.96 out of 5 average rating, 144 reviews

Steps to the Beach + Lakeviews + HotTub + Elevator

Unwind at this The Red Lakehouse just steps from the beach, featuring a private hot tub, fire pit, and covered balcony with Lake Erie views. Perfect for families, groups, and getaways, this professionally designed home offers 3 bedrooms with private ensuites for ultimate comfort and privacy. Minutes to Niagara Falls, Crystal Beach, and the USA border — yet tucked in a quiet, relaxing neighbourhood. A spotless, thoughtfully curated stay.

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