
Places to stay near Buffalo Museum of Science
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Top-rated holiday rentals near Buffalo Museum of Science
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Cozy 4BR Buffalo Home | Near Parks | Save 5% week
Historic 4BR Retreat | 7 Mins to Downtown! Relax in this 2,200 sq ft home blending historic character with a comfortable open layout. Features beautiful century-old woodwork and a fully equipped kitchen with everything you need. Highlights: • Sleeps 8: 4 roomy upstairs bedrooms. • Work & Relax: Quiet dedicated office + Zen room. • Outdoor Space: Large backyard with a patio & grill. • Great Location: 7 mins to downtown, 15 mins to airport. We're committed to a great stay. Book your getaway today!

The 2D Spot!
Buffalo's 1st official 2D Airbnb; all hand painted by local Artists. With ideal proximity to DT Buffalo, Elmwood Village & Allentown, you'll find yourself at the heart of the city's culture. Also just a 25 minute drive to the iconic Niagara Falls. Whether you're a first time visitor to Buffalo or a local seeking a unique escape, The2DSpot invites you to step inside the pages of a comic book. Immerse yourself in a world of imagination & book your stay today! Experience Buffalo like never before.

Historic Apartment Steps Away from Allentown Area
This spacious 1-bedroom apartment is conveniently located in the heart of Allentown. It is fully furnished and includes everything you will need to have a comfortable, enjoyable stay. This is 1 of 3 airbnbs located in a historic multi-unit home. This space is the perfect getaway for couples, business stays, and traveling nurses. It is situated in a quiet residential neighborhood, steps away from Allen St. The front door opens to a small park that was designed by Frederick Law Olmsted in 1887.

The Italianate: Historic Home w/ Sauna and Firepit
This beautifully restored late-1800s Victorian Italianate home offers a relaxing, centrally located retreat in Buffalo, NY, complete with a private, fenced yard containing a dry heat sauna and fire pit with complimentary firewood. Historic architectural details blend seamlessly with modern updates, including a fully stocked kitchen (coffee included). Located in the heart of Allentown, it’s an ideal stay for luxury family trips and wedding parties seeking comfort, space, and a refined home base.

Fireplace Luxury Spa Loft Gym Bball Rooftop EV+
Ideal for extended stays, this stunning luxury loft is located in an architecturally significant building in the heart of Elmwood Village and nearby Allentown. Enjoy access to top-notch amenities, including gym, dedicated work area & indoor basketball court. The loft features a unique layout with spa like amenities, couples shower and wet room, fully equipped gourmet kitchen, elegant marble finishes. Serene sunken living/sleeping area, with queen bed, gas fireplace, 65", standup work desk.

Hidden Parkside Carriage House near everything.
This beautifully redone 1915 Carriage house that is just 2 blocks from Delaware park , The zoo and the Darwin Martin house. Fully updated with plenty of room to cook and relax. 55in Smart tv and all brand new furniture. If you do not want to drive it is a 2 block walk to the train that can take you right downtown, Canalside or the Keybank Center (Sabres Arena) . Located right off the 33 so minutes to the airport , downtown and about 20 minutes to Niagara Falls and 20 to Highmark Stadium.

LarkinVille Loft (Unit 1)
If this listing is not available please check out my other listings This 1st floor loft features an open concept kitchen & living room with stove, refrigerator & microwave. A queen sleeper sofa & 46" smart TV are in the living room. The bedroom has a king bed, dresser & recliner. Washer & dryer can be found in the bathroom along with a soaker jacuzzi tub. A/C mini splits help cool down the space. This is a mix use property with periment tenants as well as other guest. Noise is typically low

Cozy Carriage House on Elmwood
Beautiful Airbnb inside a historic carriage house. Located directly on Elmwood Avenue but tucked back & secluded for a peaceful stay. Cozy interior with coffee bar included. The cottage’s prime location is within walking distance to many restaurants, bars, cafes, boutique shops, Delaware Park, the AKG and Birchfield Penney art museums, and more. Off-street parking allows easy access to adventure outside of the village with Niagara Falls & the Bills Stadium just a 20-30 min. drive/Uber away!

Five Points Hideaway
Welcome to 5 Points! Offering a private, hotel room style- 1 bedroom/1 bathroom guest suite attached to a historic home in the heart of the Five Points neighborhood on Buffalo’s Westside. Private entrance. This cozy spot is perfect for an overnight or weekend visit. Mini fridge, microwave and Keurig provided. Just 8 minutes from Downtown and 25 minutes from Niagara Falls. Walking distance to great restaurants and bars. Close to Buff State, AKG, Medical Campus, Convention Center & Arena.

Clean, Spacious, Convenient, Comfortable, Historic
- Impeccably decorated - Recently updated - 1st-floor apartment of a - Historic home - Heart of Buffalo - A few minutes to all of Buffalo's favorite spots - Budget conscious Midtown is a distinctly urban and multi-cultural neighborhood that is beginning a renaissance. If you are intimidated by the urban setting, you might be out of your comfort zone. You will see a few vacant houses and might hear a distant ambulance (nearby hospital) in this safe and quiet neighborhood.

Five Points Apartment- Upper Unit
Updated Upper Unit Apartment. Great City Location! Walking Distance to Five Points, and Lower West Side Restaurants and Shops. Off Street Parking (when available). In Unit Laundry. WiFi. Pets Allowed ($50 pet fee). Queen Bed and Fold Down Futon. Blocks from D’Youville University and minutes from Buffalo State University! Close to Kleinhans Music Hall, Elmwood Village and Allentown! 10 Min Drive To KeyBank Center - 20 Min Drive To Highmark Stadium - 20 Min Drive To Niagara Falls

Steps to the Beach + Lakeviews + HotTub + Elevator
Unwind at this The Red Lakehouse just steps from the beach, featuring a private hot tub, fire pit, and covered balcony with Lake Erie views. Perfect for families, groups, and getaways, this professionally designed home offers 3 bedrooms with private ensuites for ultimate comfort and privacy. Minutes to Niagara Falls, Crystal Beach, and the USA border — yet tucked in a quiet, relaxing neighbourhood. A spotless, thoughtfully curated stay.
Popular amenities for holiday rentals near Buffalo Museum of Science
Apartment rentals with wifi

Elmwood 1 King 1 Queen 1.5 bath Garage EV Charger

Lovely Niagara Falls Vacation Home

The Eugene

Entire Condo Minutes from Niagara Falls (USA)

Quiet nice and clean apartment downtown Buffalo

NEW, Luxurious 2BR Condo - Niagara Falls

An Artists Designed_Condo Suite (Canadian Side)

*Central location*Clean*Parking*2BDRM*A/C
Family-friendly house rentals

Bright, Beautiful Lakefront @ Historical Fort Erie

Comfortable updated home near all Buffalo sights

Beautiful Cozy House in Buffalo

Modern Kenmore Getaway | Renovated Home in Buffalo

Downtown Home W HOT TUB Private Deck & HiddenRoom

West Side Retreat Steps from Allentown & Downtown

Beautiful Victorian House

Treasure Tree
Apartment rentals with air conditioning

Cozy & Spacious Getaway! Centrally located.

Cozy North Buffalo Apartment

Inviting King & Queen Flat •Parking •Laundry •Pets

Clean 2-Bedroom Apt (11 min to DT, 12 to stadium)

Chic and Charming Apt in Downtown Allentown 2B2B

Suite Studio ❤️️ (Free Parking, Elmwood Village!)

Cozy & Walkable Elmwood Village Charmer

Tranquil Hideaway in Elmwood Village
Other great holiday rentals near Buffalo Museum of Science

The Byrnebury Studio

ArtairNorwood

Cozy apartment near Five Points

Space, comfort and hospitality!

2bdrm single family home. Medical area

Private 3 Bedroom Apartment with Porch

Grandmillennial one bedroom apt

D&C Airbnb adds home-like comfort to your travels.
Destinations to explore
- Letchworth State Park
- Holiday Valley Ski Resort
- Six Flags Darien Lake
- Niagara Falls State Park
- Niagara Falls
- Buffalo RiverWorks
- Casino Niagara
- Fallsview Indoor Waterpark
- Brock University
- Knox Farm State Park
- Jackson-Triggs Niagara Estate
- Seneca Niagara Resort & Casino
- University at Buffalo North Campus
- 13th Street Winery
- Vineland Estates Winery
- Keybank Center
- Wayne Gretzky Estates
- Legends on the Niagara Golf Course
- Kissing Bridge
- Buffalo Convention Center
- Lakeside Park Carousel
- Buffalo Zoo
- MarineLand
- Balls Falls Conservation Area





