
Places to stay near Case Western Reserve University
Book unique holiday rentals, homes and more on Airbnb
Top-rated holiday rentals near Case Western Reserve University
Guests agree: these stays are highly rated for location, cleanliness and more.

Little Italy 3, close to Cleveland Clinic, CWRU
Enjoy a uniquely styled experience at this boho-chic apartment in the heart of Little Italy. Exposed brick walls, hardwood floors, and wooden furnishings combine to give this apartment a boho-chic aesthetic. Enjoy dinner in the cozy kitchen and watch TV while relaxing on the comfortable sofa. One flight of stairs is leading up to the second floor (17 steps)The unit is on a quiet side street in walking distance to the heart of Little Italy (restaurants,cafes, shops).Free parking on premises(1car)

In the heart of Little Italy! Free Parking! 3BR-UP
Enjoy your stay at this centrally located - upper unit- in a two-family home in Little Italy. Apartment is complete with a well-equipped kitchen. The living room includes comfortable seating for 6, a smart TV, 3 poufs & coffee table - so that ALL may rest their feet from a long day, modern furnishings and a washer/dryer/linen closet. Each bedroom includes USB plugs in the lamps, alarm clocks with sound machines, blackout curtains, ceiling fans, Smart TVs, "ultra-quiet" ACs, desk, chair & mirror.

Cle Rocks-Little Italy! W Massage chair/Hot tub #2
Fall in love with this charming, newly updated 2-bedroom, 1-bath upper unit triplex apartment situated just minutes from downtown and University Circle. Complete with a well-equipped kitchen, Smart TV, laptop workspace, and modern furnishings, this vacation rental delivers all the essentials so you can spend more time relaxing and exploring. Nearby Case Western University, UH Hospital, University Circle, Cleveland Museum of Art, Cleveland Clinic, Severance Hall, Botanical Garden, and much more!!

Little Italy Two Bedroom w/ Private Drive & Patio
Stay in the heart of Cleveland's historic Little Italy, one of the city's most vibrant and walkable neighborhoods. Restaurants, cafés, bakeries, galleries, and local markets are just steps away. Whether you're visiting Cleveland Clinic, University Hospitals, Case Western Reserve University, or exploring University Circle and Downtown Cleveland, you'll enjoy a stylish first-floor apartment with two private parking spaces, a fully equipped kitchen, a private patio, and room for up to six guests.

Historic Little Italy Garden Apartment
Stylish garden apartment. This retreat blends modern comfort with the vibrant cultural charm of Historic Little Italy. Steps away from shops, restaurants, and lively bars. Wade Oval Park is a nearby cultual hub, home to The Art & Natural History Museums and Botanical Gardens. Easy access to Case Western Reserve, Cleveland Clinic and University Hospital. Walk to the beautiful Lakeview Cemetary or take transit downtown to 4th street. Perfect for short or long stays. Book for a memorable time.

Rock 'n' Roll Retreat ~15min to DT~8min Cle Clinic
Unwind in this newly renovated 2BR 1Bath Rock n' Roll retreat in a friendly & vibrant Larchmere neighborhood just 15 mins from the Rock 'n' Roll HOF. This 2nd floor apartment offers a relaxing getaway near restaurants, shops, attractions, landmarks, and major hospitals and employers, making it ideal for your stay in the Cleveland area. ✔ 2 Comfy Bedrooms w/ Queen-Size Beds ✔ Central Air and Heat ✔ Fully Equipped Kitchen ✔ Smart TV ✔ High-Speed Wi-Fi ✔ Washer/Dryer ✔ Parking See more below!

Mid-Century Modern Retreat in Little Italy
Nestled in the vibrant yet peaceful and safe Little Italy neighborhood of Cleveland, this newly remodeled Mid-Century Modern style 2bed/1bath Lower unit is within walking distance to the best Cleveland has to offer. Enjoy a stroll to Case Western Reserve University, University Circle, the Cleveland Museum of Art, Cleveland Botanical Garden, and more. Discover local shops, bakeries, and renowned restaurants that give Little Italy its charm. The RTA redline station is a five minute walk.

Private Victorian suite with two rooms and a bath
You’ll love this newly remodeled third floor suite in our large century home located near Coventry Village/University Circle/Cleveland Clinic. The private suite with separate entrance and stairs has an air conditioned large bedroom with a firm queen bed, a sunny sitting room with a futon and a bathroom (shower) finished in Victorian ornate wood trim! Off street parking is in the rear. Our place is great for couples or business travelers, and the futon can sleep a child on.

Cozy Condo l Minutes from Cleveland Clinic
Our apartment is ideally located near Cleveland Clinic, making it perfect for medical professionals, patients, and families. You’ll also be minutes from the Health Education Campus, Case Western Reserve University, University Hospitals, and the museums of University Circle. Enjoy a short drive to the charming Little Italy neighborhood, filled with authentic Italian restaurants, cafés, and bakeries, while downtown Cleveland is just 5 miles away for dining and entertainment.

2BR in Little Italy, 5 min walk to Case & UH
Enjoy a stylish experience at this centrally-located place in the heart of Little Italy. Newly renovated with a minimalist design. You are just down the street from restaurants, bakeries and bars. The RTA redline is also a two minute walk away, which takes you straight downtown as well as to the airport. Also within walking distance of Cleveland Clinic and University Circle. The apartment is located on the first floor. There is no private parking at the property.

Clean and Cozy Carriage House Getaway
Sunny and cozy carriage house in safe, historic neighborhood - perfectly appointed for overnight guests or extended stay visitors. Close proximity to Cleveland Clinic, Case Western, John Carroll University, Shaker Lakes & University Circle. Enjoy the charm of staying in this premier neighborhood with the comforts of home including updated kitchen, furnishings, bed/bedding and spa shower. Beautiful, safe, tree-lined street with private entrance and parking spot.

The Rapsodia in Blu of Little Italy *family run*
Located in Cleveland’s historic Little Italy, my two-bedroom, one-bath units are steps from Mayfield Road’s restaurants, bakeries, and galleries, with easy access to University Circle, Case Western, and the Cleveland Clinic. Hosting since 2011, I personally manage everything to provide a level of care big companies can’t match. I’m always improving my spaces to ensure a comfortable stay—if something’s missing, just let me know!
Popular amenities for holiday rentals near Case Western Reserve University
Other top sights near Case Western Reserve University
Cleveland Clinic - Main Campus Emergency Room
112 locals recommend
Cleveland Museum of Art
577 locals recommend
Case Western Reserve University
57 locals recommend
Cleveland Botanical Garden
242 locals recommend
Cleveland Museum of Natural History
236 locals recommend
Severance Music Center
106 locals recommend
Apartment rentals with wifi

Cozy Condo

Awesome 2 Bedroom Unit w/ Hot Tub and Fenced Yard

Lux Penthouse Downtown Cleveland - Rooftop Hot Tub

Luxury Top Floor Condo with a View

A Cleveland Modern & Historic Apartment 106-1

Chill Island Vibe 2BR Condo Right in Ohio City

Chic home near Cleveland airport

Cozy Downtown Modern Condo in the Heart of it all
Family-friendly house rentals

West Saint James Living

2 Min From Cle Clinic! WalkableSpacious 3BR/3.5BA!

Charming Coventry Village Hampshire Rd (Lower)

House in the Heights 4br close to Downtown

Cozy Heights Oasis-Walk to Restaurants

Quiet 4BR/2BA Home Near Cleveland Clinic

Movie Theater-Game Room-Parking-Heart Of Cleveland

Blue Historic House by Cle Clinic, CWRU, Museums
Apartment rentals with air conditioning

The Farmhouse - 1 Bdrm Apt in a Great Location

Cle Suites 1BR/1BA | 5 min Walk to Cle Clinic #7

Walkable Little Italy Gem w/ King Bed | Near CWRU

Easy Check-In 4 mins Cleveland Clinic CWRU Parking

Sleeps 3 | Cleveland Clinic + University Circle

Walk to Cleveland Clinic | Modern 1BR | Parking

Cleveland Clinic, 5 minutes from: South Suite

Jewel in the heart of Cleveland /Downtown. Unit 3
Other great holiday rentals near Case Western Reserve University

Relax at New Home & Walk to Cle Clinic

The Cleveland Coop

Cheerful, Scandinavian, Midcentury 2 bedroom home

One of a kind condo in Cleveland!

Lux top floor, 1BR Walk to Case, UH & Museums.

Little Italy · Pet Friendly · Near Clinic & Case

Little Italy · 2 TVs · 2 Cozy Beds · Fast Wifi

Prime 4BR 2.5 BA Little Italy Gem.
Destinations to explore
- Cuyahoga Valley National Park
- Rocket Mortgage FieldHouse
- Progressive Field
- Pro Football Hall of Fame
- Rock & Roll Hall of Fame
- Gervasi Vineyard
- Headlands Beach State Park
- Cleveland Browns Stadium
- Cleveland Metroparks Zoo
- Mosquito Lake State Park
- Punderson State Park
- Boston Mills
- Agora Theatre & Ballroom
- Laurentia Vineyard & Winery
- The Arcade Cleveland
- Cleveland Museum of Art
- Huntington Convention Center of Cleveland
- Crocker Park
- Edgewater Park Beach
- Debonné Vineyards
- JACK Cleveland Casino
- Cleveland Museum of Natural History
- Rocky River Reservation
- Stan Hywet Hall and Gardens





