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Guest house holiday rentals in Cayman Islands

Find and book unique guest house rentals on Airbnb

Top-rated guest house rentals in Cayman Islands

Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

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Top guest favourite
Guest house in West Bay
5 out of 5 average rating, 12 reviews

Cozy Cottage

Escape to the Cozy Cottage Prime Location: A peaceful retreat w/all essentials for those seeking an island getaway or for business travelers. Beach Access: A leisure 8-min walk to the quieter end of 7 Mile Beach for turquoise waters and unforgettable sunsets. Nearby Amenities: Restaurants, clinics, pharmacy, supermarket, etc Easy Transportation: A nearby bus stop offers island-wide access if needed. Enjoy comfort, tranquility & island charm at Cozy Cottage. We look forward to hosting you!

Top guest favourite
Guest house in Cayman Islands
5 out of 5 average rating, 63 reviews

Tua'r Mor (near the sea) quiet waterfront escape.

This lovely one-bedroom, one-bath charismatic bungalow is located in the quiet neighborhood of Sunrise Landing, Newlands, and is perfect for couples or small families. Tua’r Mor provides everything you need to feel at home, with an open kitchenette and dining/living area. The unit has everything from beach towels, beach chairs, and coolers so you can enjoy a day out. A hammock awaits you in your own private garden, overlooking the canal, where you can enjoy watching the sun rise or set.

A serene beachside scene showcases a gently swaying palm tree against the backdrop of a tranquil ocean. A sandy area with a stony path leads toward the water, while lush greenery frames the view, enhancing the coastal environment.
Guest house in Cayman Brac
4.92 out of 5 average rating, 24 reviews

Vista Del Mar Beach House#2

This Lovely new Beach House is located on the South Side, West End of Cayman Brac, Walking Distance to Restaurants and Bars, Dive Shop, Big daddy's Liquor Store. Our Guest House Features 2 separate Units each with one bedroom and a pull out Sofa bed. one Bathroom, and Kitchen. Amenities include Internet Wifi and Television Vista Del Mar Beach house is perfect for a Romantic Getaway with Beautiful Ocean views of the Sea. Open Porch at the Beach, Deck Chairs and Hammock. Perfect Relaxation.

Guest house in Bodden Town
5 out of 5 average rating, 3 reviews

Relaxed Island Stay | 2BR Bodden Town Unit 1

Escape to your cozy, modern 2BR, 2BA duplex in Bodden Town, fully furnished and perfect for up to 4 guests. Relax in a very quiet, safe neighborhood with a police station, clinic, gas stations, and convenience stores nearby. Just 2 minutes from local Bodden Town beaches and 30–45 minutes from the famous Seven Mile Beach. Ideal for families, couples, or small groups seeking comfort, style, and tranquility in Grand Cayman. Vehicles are available for rent ranging from USD $50-$75 per day.

Guest favourite
A sandy area is framed by lush palm trees, casting intricate shadows on the ground. In the background, the calm ocean is visible, bordered by a line of tropical greenery under a clear blue sky.
Guest house in Bodden Town
5 out of 5 average rating, 11 reviews

Andy's Inn #1 Oceanview Guesthouse

Prepare to indulge in the perfect island retreat in the historic first capital of Bodden Town where island charm meets hospitality. Andy's Inn is a delightful locally owned and operated guesthouse complete with all the touches of home. Great ocean views, luxury furnishings and refreshing sea breeze which offers the perfect atmosphere to unwind, relax and enjoy our Island paradise. When you stay at Andy's Inn you will get to make some memories at this unique and family-friendly place.

Top guest favourite
A serene sleeping area is centered around a spacious bed adorned with a light blue quilt and an orange throw. Two decorative prints hang above the headboard. White walls and modern sconce lighting enhance the calm ambiance, complemented by a round mirror nearby.
Guest house in Grand Harbour
4.97 out of 5 average rating, 193 reviews

Heavenly Suite 2 - The M @ The Edge

Heavenly Suíte #2 at The M @ The Edge is a studio apartment with sleek & modern furnishings, smart HD TV, sound bar, chandeliers, state of the art kitchenette with quartz counter-tops, Delta faucet, and under counter lights. The chic bedroom fashioned in white crisp tiles, scones and recessed lighting mimics the luxurious bath styled in porcelain & Carrera tiles, Delta faucets, mirrors. . The patio enlivened by red/white accents, greenery, bar, pergolas, and Jacuzzi.

Guest favourite
Guest house in Bodden Town
4.96 out of 5 average rating, 23 reviews

Cozy Studio close to Hospital, Beach & Restaurants

Welcome to our charming tropical-themed studio, a hidden gem nestled behind the inviting House on The Hill in the heart of Grand Cayman. This cozy studio retreat is perfect for those seeking a comfortable, inviting space to rest after exploring the island. The home is located in the center of the island and is located off the main arterial road, providing easy access to all sides of the island. It is close to beaches and 5 minutes from supermarkets and restaurants.

Guest house in George Town
4.85 out of 5 average rating, 195 reviews

Zen Den 3, cozy private studio in George Town

Welcome to this private cozy studio in the vibrant heart of George Town! Lokated 10-15 minute walking distance to Smiths Cove Beach, this is separate unit with an independent entry. Has a bedroom, kitchenette, washer dryer, bathroom and designated parking spot. Located in George Town near hospitals, pharmacy, gas station and restaurants. Bedroom has queen bed, split A/C, smart TV and Internet. Private outside patio with seating and a hammock.

Guest house in Rum Point

Hello Sunshine! Retreat@RumPoint

Discover Unit 18 at The Retreat, a hidden gem on Grand Cayman’s peaceful North Side. This oceanfront condo offers breathtaking views, privacy, and direct beach access. Enjoy a spacious layout with floor-to-ceiling windows and stunning sunsets over the sea. Located in Cayman Kai near Rum Point Beach Club, you’ll find world-class snorkeling, dining, and calm waters just steps away. Perfect for a tranquil island escape.

Top guest favourite
An inviting entrance features wooden steps leading up to double French doors. A vibrant mural of tropical flowers and leaves decorates the wall, while potted plants and garden furniture create a welcoming atmosphere. Sunlight filters through, enhancing the serene courtyard setting.
Guest house in West Bay
4.93 out of 5 average rating, 29 reviews

Plant Based Studio Apartment

Plant Based Studio is located on Grand Cayman is just a stone's throw away from the beautiful 7 Mile Beach. This private hideaway has its own private entrance and lush botanical courtyard, it is the perfect place to unwind and escape the hustle and bustle. Located along the 7 mile corridor, it is near all restaurants and shopping. Convenient for work, play or whatever suits you.

Superhost
A small outdoor seating area is surrounded by lush greenery, featuring a white table and two chairs in vibrant colors. Sunlight filters through the foliage, creating a serene and inviting space for relaxation.
Guest house in West Bay
4.79 out of 5 average rating, 19 reviews

Da' Place

Take it easy at our unique and tranquil little charming island gem. Da' Place is nestled in it's own corner of paradise, surrounded by nature and it's beauty. Our 1 bedroom cottage sports a spacious bathroom and fully equipped kitchen. Near to the main bus route and minutes away from our pristine beaches and popular attractions and food sources and shops..

Top guest favourite
The exterior view of the pool house is presented, featuring a light grey façade and a metal roof. Large glass sliding doors provide access to an outdoor area, complemented by a wooden deck and lounge seating. Lush greenery is visible in the background.
Guest house in West Bay
4.98 out of 5 average rating, 55 reviews

Highlands Pool House

Our quaint pool house is just minutes walk from world famous Cemetery Beach at the north end of 7 Mile Beach. Conveniently located near Fosters Shopping Center in West Bay and easy access to the heart of 7 Mile Beach, Camana Bay and the airport. *Note that the pool is reserved for the owners of the house and not available to guests.

Popular amenities for guest house rentals in Cayman Islands