Guest house holiday rentals in Durham County

Light-filled Guesthouse Near Duke

Second floor of recently-built garage apartment in a charming, peaceful Durham neighborhood. Twenty minutes to RDU Airport, five minutes to Duke's East Campus and ten minutes to West Campus, we are an easy walk to a range of locally-owned restaurants. Lovely, light-filled apartment has a bedroom, full kitchen and living area, bathroom, private entrance, and patio with seating. Occasionally, we may have first-floor space available at extra cost. Well-behaved pets welcome. See below for fees.

Modern Cottage With a Vintage Twist Near Downtown

Come stay at our modern vintage guesthouse in Historic Trinity Park. Our cottage has all modern appliances with vintage fixtures. Our cottage is a cozy, lived-in retreat with rustic charm. This 380 square foot cottage is located in a very lively and safe neighborhood just minutes from downtown Durham. Walk one mile on the Ellerbe creek trail to downtown! Walk 1.5 mile to 9th street restaurants and shops 1 mile to Central Park and farmers market <1 mile to bars and restaurants on geer street

Little House Old North Durham

Welcome to our little house in Old North Durham. The 380 square foot studio guest house (open concept) sits behind our Bungalow in a centrally located historic neighborhood.; a 15-20 minute walk to Durham's vibrant Central Park District and a little further to downtown. Close by restaurants, music, movies and shows. Sleeps 2 comfortably on queen bed, and 2 additional on convertible couch from IKEA. Living area joins kitchen and is open to bedroom (see photos). Vaulted ceilings create openness.

East Campus Spacious Guest house

You'll have plenty of space in this beautiful, sun-soaked, fully-stocked, 1-bedroom guest house. Literally just steps from Duke's East Campus, you have easy access to everything. It's a short walk to two grocery stores (including Whole Foods), restaurants, shops, and a popular walking/jogging loop, and just a mile and a half to downtown or Duke hospital. Or stay in and lounge on the massive deck, cook a meal in the full-sized kitchen, or stream your favorite shows in this brand-new space.

Studio on Tobacco Road

Whether you're coming to work or play, Studio on Tobacco Road is a perfectly positioned launch pad to experience Durham & Chapel Hill. Just 6 miles to Downtown Durham's renowned breweries & culinary scene, experience its creative arts culture & explore its rich history. Minutes from your home court, 4 miles to Duke. 5 miles to UNC. All from a beautifully designed studio on a quiet, nature-rich landscape less than a mile from Duke Forest. Gravel drive was recently paved! Photos to come!

“Meelie Doll”~ Private - Cozy Stdio Apt abv garage

Cute Studio apt, w/private entrance, nestled in the trees, including major amenities along with prkg on premises. Relax after a long day out by strolling the quiet neighborhood to get your steps in. Close to RTP and all Major Co.'s in the pk. Close to all Major Trigle Collges, Univ.'s & Hospitals including Duke, UNC, NC St. all within 15-20 mins away. 10 mins to RDU Airpt, Shopping & Restaurants. You will Love it!! If longer stay is needed please contact me.

Duplex filled with natural light

A stylish, modern, and beautiful alley guesthouse that is located just 2 blocks from Duke's East Campus and 4 blocks from downtown Durham. The apartment is located in the historic Trinity Park Neighborhood in Durham. The apartment has a top of the line finish, hardwood floors, appliances, and furniture. The loft area is equipped with a standing desk and monitor and 2 Yoga matts, and it is ideal for working professionals visiting the area. Built: 2023

Duke Forest Hideaway

Enjoy some tranquil time at our Duke Forest Hideaway. The guest house is located inside our safe gated property adjacent our 35 acre horse farm. Just outside the front door you will have access to a mile of wooded walking trails around the farm. Just 2 miles from Duke, 5 miles from downtown Durham UNC you are still in the center of everything! The unit has a private entrance and parking, patio, stocked full kitchen, and washer dryer.

Chic Poolside Hideaway Near Duke & UNC

Tucked away in the back of our 1927 property sits The Sidekick, a thoughtfully restored carriage house surrounded by peaceful woods & grand homes. Part cowboy clubhouse, part restful retreat, The Sidekick is a conveniently-located getaway for couples, solo travelers, or small groups. Take a dip in the saline pool, lounge in the mature garden, or just rest your sleepy head on luxurious linens in your sweet lil' loft bedroom.