
House holiday rentals in Guadalupe
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Top-rated house rentals in Guadalupe
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Coastal Getaway, Country House, near 101 FWY
Country house surrounded by trees with many windows, wooden floors, lovely kitchen, large sunroom, and huge deck. All located just minutes from Pismo, Grover, Shell and Avila Beach, hot springs, hiking areas, wineries, golf courses, Lake Lopez, ATV riding & outlet shopping, Trader joe's and many other stores. San Luis Obispo is a lovely city just minutes north. and Hearst Castle is less than an hour's drive North. Conveniently situated off the 101 freeway, a nice retreat from the big city.

Hillside view with hot tub too
This house is the 2nd home on the property (main home is also STR). Located at the top of a private driveway with a beautiful view of the hills. Fully stocked kitchen with fridg/freezer, dishwasher, oven, 5 burner stove, microwave, ice maker, osmosis system, fully automatic espresso maker. 65” QLED TVs in living room and bedrooms. Patio furniture wiith covered gazebo, gas BBQ, pellet smoker/BBQ, patio heaters, fire table. Hot tub with gazebo accommodates 6. EV/Tesla charger in garage.

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT
Step into history at this charming 2-bedroom railroad house in downtown SLO. Enjoy its preserved heritage, from the 11-foot tall ceilings to the spacious kitchen. Sleep luxuriously on Purple mattresses in both bedrooms. Unwind next to the fire pit in the backyard. It's a short 7 min. stroll to downtown & next to 5 restaurants including Sally Lou's coffee shop & the train station. Experience SLO's charm like never before with this perfect location home. Send us a message to plan your trip!

Spacious SLO CAL Home w/ Pool, Spa. Pet Friendly!
Relax and recharge at this pet-friendly retreat in Arroyo Grande, perfect for families, couples, and special occasions! Enjoy your own heated pool (seasonally heated Apr-Oct), year-round heated spa, and spacious yard in a peaceful neighborhood. Just minutes from iconic spots like Pismo Beach, Avila Beach, and Cal Poly, it’s ideal for exploring wineries, hiking, and the stunning Central Coast. Whether you’re celebrating or relaxing, this home offers everything for an unforgettable stay.

Gateway to SLO County with Pickleball & Game Room
Family fun awaits at this 4500 sq feet home base to explore everything that San Luis County has to offer. Originally a log home, the home has been tastefully updated throughout the years and has a spacious open layout. There are 4 bedrooms, 3 bathrooms, a theater room, a game room and covered patio. There's something for everyone in the backyard with sports court, fire pit and bocce ball. Walk 2 minutes to 140 acre Nipomo Regional Park with new skate park & tennis and basketball courts.

Cozy Plant-Filled Loft | Near Wineries & Beaches
Stylish, plant-filled loft on the Central Coast! Relax under cozy lights surrounded by greenery in this peaceful, thoughtfully designed studio with everything you need. Enjoy a comfy living area with TV, kitchenette, WiFi, and private entrance for easy access. Located just minutes from Old Orcutt’s coffee shops, wine tasting rooms, and restaurants, with quick access to Solvang, SLO, and beaches. Perfect for a quiet getaway, work stay, or exploring the beautiful Central Coast.

San Luis Obispo Wine Country Retreat
Escape to a luxurious three-bedroom farmhouse on a shared 10-acre ranch in San Luis Obispo's Edna Valley, surrounded by rolling hills of renowned vineyards. Newly renovated with modern amenities including a spacious kitchen, cozy living room with smart TV, and private patio with fire pit. Sleeps up to six guests with AC, heating, WiFi, and BBQ grill included. Explore nearby wineries and restaurants or relax on the private patio. Book now for a memorable California getaway.

Private pond & views of rolling green hills
Welcome to Grandview in Buellton, CA, in the heart of Santa Barbara Wine Country. Perched on 23 acres amidst rolling hills and breathtaking views, this rustic retreat comes lined with grape vines and a private pond. Sid by the pond and relax and sip local wines on the pier admiring the view. At the end of the day cook up delicious meals while taking in the gorgeous sunsets from the wrap-around deck. Please note: There is a quiet, long-term tenant/caretaker on site.

Luxe Hideaway: Prvt Patio BBQ Winery, 20 min-Beach
Agreement: Bookings require a signed Renter Agreement, please check your email to complete booking. Kick back & relax in this calm, modern space. Enjoy the privacy of your own home with contactless check-in, high speed internet, comfortable beds, pull-out memory foam sofa sleeper for added guests, full kitchen just waiting for your culinary desires, and a patio with dining set for 6. Enjoy being centrally located while you explore the beautiful central coast.

Wine cellar House
Welcome to Bodega House, a restored 1920s farmhouse in the center of Los Alamos. The home features a serene queen bedroom and a separate lounge space, along with a sleeper sofa in the living area. Thoughtfully designed for two adults, the house can also comfortably host one to two children on the sleeper sofa. It’s an ideal setting for couples or small families seeking the ease and privacy of a home while being just steps away from the best of Los Alamos.

Wine Country Hilltop Retreat
Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

Mid-century home in the heart of Arroyo Grande.
Welcome to the Eman House! I can't wait to host you at the 1950's mid century in Arroyo Grande, CA. Enjoy the beautiful remodeled kitchen, private backyard and patio, and two cozy bedrooms while soaking up the best of the central coast. Just a 10 minute walk to the historic Arroyo Grande village, a 5 minute drive to the beaches of Grover, and tucked away in one of Arroyo Grande's most peaceful cul-de-sacs.
Popular amenities for house rentals in Guadalupe
House rentals with a pool

Hidden Views

Pool & view in Sta Rita Hills Wine Country, Lompoc

San Luis Obispo House With Pool And Hot Tub

Fairway to Heaven

Getaway at the Highlands+Heated Pool+Hot Tub

FairView Lavender Estate

Ranch Style Home w/ Bikes! Heart of Wine Country

Historic 1895 Edna Railhouse with Heated Pool
Weekly house rentals

Windermere Villa-Jacuzzi, Ocean Views,Ping Pong

Guesthouse in Ballard

Casa Del Mar

The Quailhouse on Ranch near Avila Beach

Working Ranch~Golf, Beach,Wine/No smoking/Pet free

Beach, Wine Country, & Golf adjacent home for 8

Luxury Village Home

Perfect Central Coast Getaway Retreat Close to All
Private house rentals

Cute Grover Beach cottage STR-0068

Mid Century Modern Loft Downtown SLO

Oceano Home with a View

Beautiful Country Home

1 Block from Beach with long driveway for parking

|Safe|BBQ | Hot Tub| 4 Bedrooms| Deck With Views

Well Appointed 3BR Home | Steps to Town |Fireplace

Farmhouse located on San Luis Obispo Central Coast
Destinations to explore
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- Cayucos Beach
- Pismo State Beach
- El Capitán State Beach
- Morro Strand State Beach
- Montaña de Oro State Park
- Cayucos State Beach
- Los Padres National Forest
- Morro Rock Beach
- Morro Bay Golf Course
- California Polytechnic State University
- Solvang Windmill
- Mission San Luis Obispo de Tolosa
- Oceano Dunes State Vehicular Recreation Area
- Dinosaur Caves Park
- Sensorio
- Pismo Preserve
- Charles Paddock Zoo
- Monarch Butterfly Grove
- Vina Robles Amphitheatre
- Tablas Creek Vineyard
- Nojoqui Falls Park
- Downtown City Park
- Talley Vineyards
- Niner Wine Estates





