Boutique hotels in Iowa

Find and book unique boutique hotels on Airbnb

Top-rated boutique hotels in Iowa

Guests agree: these boutique hotels are highly rated for location, cleanliness and more.

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Guest favourite

A quaint dining area is featured with a round table and two wooden chairs, complemented by a soft area rug. A crystal chandelier hangs above, while light green walls and natural light from a window enhance the space. A small dresser adds functionality.

Hotel room in Kanawha

5 out of 5 average rating, 15 reviews

The Mainline Depot Langevin Suite

You won’t want to leave this charming, one-of-a-kind suite located in an old 1900's Farmer's State Bank. You will feel right at home in this 1 bedroom suite featuring a stunning antique crystal chandelier, kitchenette with granite counter and all the amenities needed. There is also a laptop friendly desk and internet for those who need to work while away from home. The comfortable living room offers a stylish sofa and chair and cable TV. The cozy luxury bedding makes bedtime so inviting!

A quaint bedroom features a wooden bed with an intricately carved headboard, complemented by a light-colored quilt. A small nightstand with a lamp sits beside the bed, while a dresser displays various personal items. Natural light enters through a partially draped window.

Hotel room in Allerton

4.75 out of 5 average rating, 12 reviews

Inn of the Six-Toed Cat -- Rosalie Room

Inn of the Six-Toed Cat, where you can take life a little slower at an authentic turn of the century Inn. We have common rooms for guests to relax, read, play games or watch TV/movie. We provide a wonderful breakfast with warm hospitality. Near by is the highly acclaimed Prairie Trails Museum (in Corydon), Bob White park, Round Barn, Amish country, golfing and lost of little antique stores in the neighboring towns. Come enjoy the front porch lifestyle, and let us be your home away from home.

Guest favourite

The exterior of the historic American House Inn is depicted, showcasing its vintage brick façade and prominent entrance. Large glass windows allow views of the surrounding area, while a plaque indicating the year 1854 is visible above the door. Seating is available on the sidewalk.

Hotel room in McGregor

4.9 out of 5 average rating, 21 reviews

American House 1854- Stagecoach Stop Suite

Take in the beauty of the Mississippi River at this unique and tranquil getaway. The American House Inn is the oldest standing building in McGregor, IA. Built in 1854, this building is on the National Registry of Historic Places and takes you back to the late 1800s but with modern amenities. Located just across the street from Big Bouys Marina, Kwik Star and a block from the Sadie’s Sweet Ice Cream shop! You don’t want to miss enjoying all of the history and the beauty of this vintage gem!

A charming sleeping area is highlighted by a black bed frame with an elegant headboard. Soft linens with a decorative throw pillow are placed on the spacious bed. Gentle light filters through sheer curtains, illuminating the room's details, including a vintage chandelier and tasteful table lamps.

Hotel room in Kanawha

5 out of 5 average rating, 4 reviews

The Mainline Depot Pedersen Suite for 2

You will feel right at home in this charming luxury studio apartment suite located in an old 1900's Farmer's State Bank. This unique suite has a queen sized bed with a stunning antique chandelier. There is a full sized kitchen with quartz counters that has everything you need and an inviting dining room to eat your meals. Snuggle up on the stylish sofa and enjoy the a cozy electric fireplace and cable TV. (See separate listing to include the bunk room that sleeps an additional 6 guests!

The exterior of The Continental Hotel features a classic brick facade with a striped awning over the entrance. Potted greenery decorates the porch, and a menu board is positioned nearby, showcasing the dining options available.

Hotel room in Centerville

Private Townhome Apartment in Historic Hotel

Offering elegance, history, and genuine hospitality, The Continental Hotel is southern Iowa’s premier boutique hotel. A hidden gem on the historic Centerville Square, our 28-room hotel dates to 1866. We have hosted a number of famous historical figures including Booker T. Washington and Carrie Nation. The Continental has a restaurant, Lucile's, on the main level that serves lunch and dinner. Free continental breakfast is available here and is included with your stay.

Hotel room in Cresco

New place to stay

Room 20 At The Cresco Motel

Enjoy a comfortable and convenient stay in this cozy motel room located in the heart of Cresco. Perfect for families, coworkers, or friends traveling together, this space features two comfortable double beds, a private bathroom, free high-speed Wi-Fi, and all the essentials for a relaxing visit. Whether you're staying for business, passing through on a road trip, or planning a longer visit, this room offers the comfort and simplicity you need for a pleasant stay.

Hotel room in De Witt

Boutique Motel | Queen Room 5

The Vandenburg, formerly the Winsther, is a classic roadside motel under new ownership. During this transition, guests may still notice some signage or references to the former name around the property. While updates will come over time, our current focus is on offering a clean, comfortable, and welcoming stay. Whether you're passing through DeWitt for work, visiting family, or simply needing a convenient place to rest, we’re glad to host you.

Top guest favourite

An indoor pool area features large windows allowing natural light to fill the space. The pool is framed by a retractable roof, and there are steps leading down into the water. Lush greenery can be seen outside through the panoramic glass walls.

Hotel room in Le Claire

4.96 out of 5 average rating, 27 reviews

The Magnolia Suite - Deluxe King, STE 202

Welcome to our luxurious King Suite! This elegant suite features a king-size bed, perfect for a restful night's sleep, and a sofa bed for extra guests. The highlight of the suite is the indulgent jetted tub, where you can unwind and relax after a long day. The large walk-in shower offers a refreshing and invigorating experience. Enjoy entertainment on the flat screen TV and stay connected with free WiFi!

Guest favourite

An indoor pool is enclosed by expansive glass walls, allowing natural light to fill the area. The pool features a dark tiled border and steps leading into the water. Lush greenery is visible outside through the glass, adding to the serene atmosphere.

Hotel room in Le Claire

4.76 out of 5 average rating, 21 reviews

The Golden Suite - 2 Queen, STE 102

Discover comfort and relaxation in our luxurious Golden Suite. This suite offers two queen beds, a sofa-bed, 2 walk-in showers, two bathroom stalls and a private sauna. Stay entertained with the flat screen TV, and keep refreshments close at hand with the mini fridge and in-room coffee maker. Enjoy the scenic view of the Mississippi River from your private walkout while staying connected with free WiFi.

The indoor pool area features large glass windows that provide ample natural light. The elegantly shaped pool is surrounded by lounge chairs, with greenery visible through the windows, enhancing the tranquil ambiance. Retractable roofing allows for open-air relaxation.

Hotel room in Le Claire

5 out of 5 average rating, 5 reviews

The Serenity Suite - 2 Queen, STE 101

Discover comfort and relaxation in our luxurious Aqua Suite. This suite offers two queen beds, a sofa-bed, 2 walk-in showers, two bathroom stalls and a private sauna. Stay entertained with the flat screen TV, and keep refreshments close at hand with the mini fridge and in-room coffee maker. Enjoy the scenic view of the Mississippi River from your private walkout while staying connected with free WiFi.

Guest favourite

A spacious bedroom is presented with a king-size bed, dressed in a deep red patterned cover. Two accent chairs are positioned near a side table, while a door leads to another area. Soft lighting is provided by bedside lamps, enhancing the cozy environment.

Hotel room in Washington

4.92 out of 5 average rating, 39 reviews

King Suite - Dodici Night Suites

Above the famous Dodici Cafe Restaurant in beautiful downtown Washington, This suite is newly built in 2016. King size bed with sitting area and bath Extra bedroom with queen size bed Other Amenities: Private Bath with Hair Dryer and Bath Products, Air-conditioning, Refrigerator, Microwave, Coffee Maker, Dining Table, TV, Free Wi-Fi

A vibrant beauty parlor is visible through a large window, featuring a neon sign that reads 'Beauty Parlor'. The interior is adorned with pink lighting, modern salon chairs, and decorative elements that create an inviting contemporary space.

Hotel room in Monticello

The Monticello Motel - Full Property

A boutique 1950’s roadside motel offering upscale amenities like premium snack trays. Including common areas that are ready to unwind in with your friends and family. Rent the entire property for your next small gathering or girls trip. This hip spot offers more than just distinctive decor. It’s unlike any motel you’ve never stayed at before!