Boutique hotels in Iowa

Find and book unique boutique hotels on Airbnb

Top-rated boutique hotels in Iowa

Guests agree: these boutique hotels are highly rated for location, cleanliness and more.

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Guest favourite

A quaint dining area is featured with a round table and two wooden chairs, complemented by a soft area rug. A crystal chandelier hangs above, while light green walls and natural light from a window enhance the space. A small dresser adds functionality.

Hotel room in Kanawha

5 out of 5 average rating, 15 reviews

The Mainline Depot Langevin Suite

You won’t want to leave this charming, one-of-a-kind suite located in an old 1900's Farmer's State Bank. You will feel right at home in this 1 bedroom suite featuring a stunning antique crystal chandelier, kitchenette with granite counter and all the amenities needed. There is also a laptop friendly desk and internet for those who need to work while away from home. The comfortable living room offers a stylish sofa and chair and cable TV. The cozy luxury bedding makes bedtime so inviting!

A quaint bedroom features a wooden bed with an intricately carved headboard, complemented by a light-colored quilt. A small nightstand with a lamp sits beside the bed, while a dresser displays various personal items. Natural light enters through a partially draped window.

Hotel room in Allerton

4.75 out of 5 average rating, 12 reviews

Inn of the Six-Toed Cat -- Rosalie Room

Inn of the Six-Toed Cat, where you can take life a little slower at an authentic turn of the century Inn. We have common rooms for guests to relax, read, play games or watch TV/movie. We provide a wonderful breakfast with warm hospitality. Near by is the highly acclaimed Prairie Trails Museum (in Corydon), Bob White park, Round Barn, Amish country, golfing and lost of little antique stores in the neighboring towns. Come enjoy the front porch lifestyle, and let us be your home away from home.

Guest favourite

The exterior of the historic American House Inn is depicted, showcasing its vintage brick façade and prominent entrance. Large glass windows allow views of the surrounding area, while a plaque indicating the year 1854 is visible above the door. Seating is available on the sidewalk.

Hotel room in McGregor

4.9 out of 5 average rating, 21 reviews

American House 1854- Stagecoach Stop Suite

Take in the beauty of the Mississippi River at this unique and tranquil getaway. The American House Inn is the oldest standing building in McGregor, IA. Built in 1854, this building is on the National Registry of Historic Places and takes you back to the late 1800s but with modern amenities. Located just across the street from Big Bouys Marina, Kwik Star and a block from the Sadie’s Sweet Ice Cream shop! You don’t want to miss enjoying all of the history and the beauty of this vintage gem!

A charming sleeping area is highlighted by a black bed frame with an elegant headboard. Soft linens with a decorative throw pillow are placed on the spacious bed. Gentle light filters through sheer curtains, illuminating the room's details, including a vintage chandelier and tasteful table lamps.

Hotel room in Kanawha

5 out of 5 average rating, 4 reviews

The Mainline Depot Pedersen Suite for 2

You will feel right at home in this charming luxury studio apartment suite located in an old 1900's Farmer's State Bank. This unique suite has a queen sized bed with a stunning antique chandelier. There is a full sized kitchen with quartz counters that has everything you need and an inviting dining room to eat your meals. Snuggle up on the stylish sofa and enjoy the a cozy electric fireplace and cable TV. (See separate listing to include the bunk room that sleeps an additional 6 guests!

The exterior of The Continental Hotel features a classic brick facade with a striped awning over the entrance. Potted greenery decorates the porch, and a menu board is positioned nearby, showcasing the dining options available.

Hotel room in Centerville

Private Townhome Apartment in Historic Hotel

Offering elegance, history, and genuine hospitality, The Continental Hotel is southern Iowa’s premier boutique hotel. A hidden gem on the historic Centerville Square, our 28-room hotel dates to 1866. We have hosted a number of famous historical figures including Booker T. Washington and Carrie Nation. The Continental has a restaurant, Lucile's, on the main level that serves lunch and dinner. Free continental breakfast is available here and is included with your stay.

Hotel room in Cresco

Room 20 At The Cresco Motel

Enjoy a comfortable and convenient stay in this cozy motel room located in the heart of Cresco. Perfect for families, coworkers, or friends traveling together, this space features two comfortable double beds, a private bathroom, free high-speed Wi-Fi, and all the essentials for a relaxing visit. Whether you're staying for business, passing through on a road trip, or planning a longer visit, this room offers the comfort and simplicity you need for a pleasant stay.

Guest favourite

An indoor pool is enclosed by expansive glass walls, allowing natural light to fill the area. The pool features a dark tiled border and steps leading into the water. Lush greenery is visible outside through the glass, adding to the serene atmosphere.

Hotel room in Le Claire

4.76 out of 5 average rating, 21 reviews

The Golden Suite - 2 Queen, STE 102

Discover comfort and relaxation in our luxurious Golden Suite. This suite offers two queen beds, a sofa-bed, 2 walk-in showers, two bathroom stalls and a private sauna. Stay entertained with the flat screen TV, and keep refreshments close at hand with the mini fridge and in-room coffee maker. Enjoy the scenic view of the Mississippi River from your private walkout while staying connected with free WiFi.

Guest favourite

The Aqua Suite features two queen beds with neutral bedding, complemented by soft blue accent pillows. A cozy seating area includes two chairs on a patterned rug, while large glass doors provide a view of the Mississippi River and access to a private walkout.

Hotel room in Le Claire

4.83 out of 5 average rating, 6 reviews

The Serenity Suite - 2 Queen, STE 101

Discover comfort and relaxation in our luxurious Aqua Suite. This suite offers two queen beds, a sofa-bed, 2 walk-in showers, two bathroom stalls and a private sauna. Stay entertained with the flat screen TV, and keep refreshments close at hand with the mini fridge and in-room coffee maker. Enjoy the scenic view of the Mississippi River from your private walkout while staying connected with free WiFi.

A vibrant beauty parlor is visible through a large window, featuring a neon sign that reads 'Beauty Parlor'. The interior is adorned with pink lighting, modern salon chairs, and decorative elements that create an inviting contemporary space.

Hotel room in Monticello

The Monticello Motel - Full Property

A boutique 1950’s roadside motel offering upscale amenities like premium snack trays. Including common areas that are ready to unwind in with your friends and family. Rent the entire property for your next small gathering or girls trip. This hip spot offers more than just distinctive decor. It’s unlike any motel you’ve never stayed at before!

A bright and airy room is highlighted by large windows that offer views of the lake. A comfortable sofa sits opposite a spacious bed, while a mounted television is positioned on the wall. A small balcony is visible through the sliding glass doors.

Hotel room in Clear Lake

4.78 out of 5 average rating, 41 reviews

Lakeside Inn - Clear Lake - Standard King

Charming king room at the newly renovated Lakeside Inn in Clear Lake, IA. In addition to the brand new renovations, you'll also enjoy a one of a kind view of the gorgeous lake. Offering an array of rooms, some with patios, we are here to make your stay an experience to remember.

Guest favourite

A spacious sleeping area features a contemporary bed with gray bedding. Two windows, framed by light curtains, allow natural light to illuminate the room. A desk and chair are positioned against one wall, while a standing lamp adds a warm glow beside a dresser.

Hotel room in Clarinda

5 out of 5 average rating, 7 reviews

Garrison Loft

Enjoy a stylish experience at this centrally-located place. Enjoy shopping, history, restaurants right on our square. You also get lunch or breakfast for up to 2 people at no charge to you.

A spacious lobby area features a stone fireplace beneath a wooden mantle, with logs stacked neatly. Rustic sofas with nature-inspired upholstery and a wooden coffee table provide seating. A deer head mount decorates the wall above, contributing to the lodge's warm atmosphere.

Hotel room in Sioux City

5 out of 5 average rating, 4 reviews

Deluxe 2 Queen, Stoney Creek Sioux, Pool | 2 Units

Enjoy rustic charm near Hard Rock Casino, Tyson Events, Missouri River, and history. Ideal for gaming, shows, views, and local culture. Perfect for leisure or business.