
Boutique hotel holiday rentals in Iowa
Find and book unique boutique hotel rentals on Airbnb
Top-rated boutique hotel rentals in Iowa
Guests agree: these boutique hotel rentals are highly rated for location, cleanliness and more.

The Best Spot for a Relaxing Getaway! W/ Pool, Gym
While staying with us, unwind and take advantage of everything the city has to offer. Our property in Ankeny is near I-35. Drake University, Principal Park, and the Iowa State Capitol in Des Moines are all about 15 minutes away. Big Creek State Park, located on Saylorville Lake, is a short 25-minute drive away. The distance to Ankeny Regional Airport will be 10 minutes. Enjoy a complimentary hot breakfast each morning before heading out on a day of adventure. Parking and Wi-Fi are also free.

Inn of the Six-Toed Cat -- Rosalie Room
Inn of the Six-Toed Cat, where you can take life a little slower at an authentic turn of the century Inn. We have common rooms for guests to relax, read, play games or watch TV/movie. We provide a wonderful breakfast with warm hospitality. Near by is the highly acclaimed Prairie Trails Museum (in Corydon), Bob White park, Round Barn, Amish country, golfing and lost of little antique stores in the neighboring towns. Come enjoy the front porch lifestyle, and let us be your home away from home.

American House 1854- Stagecoach Stop Suite
Take in the beauty of the Mississippi River at this unique and tranquil getaway. The American House Inn is the oldest standing building in McGregor, IA. Built in 1854, this building is on the National Registry of Historic Places and takes you back to the late 1800s but with modern amenities. Located just across the street from Big Bouys Marina, Kwik Star and a block from the Sadie’s Sweet Ice Cream shop! You don’t want to miss enjoying all of the history and the beauty of this vintage gem!

The Mainline Depot Pedersen Suite for 2
You will feel right at home in this charming luxury studio apartment suite located in an old 1900's Farmer's State Bank. This unique suite has a queen sized bed with a stunning antique chandelier. There is a full sized kitchen with quartz counters that has everything you need and an inviting dining room to eat your meals. Snuggle up on the stylish sofa and enjoy the a cozy electric fireplace and cable TV. (See separate listing to include the bunk room that sleeps an additional 6 guests!

Private Townhome Apartment in Historic Hotel
Offering elegance, history, and genuine hospitality, The Continental Hotel is southern Iowa’s premier boutique hotel. A hidden gem on the historic Centerville Square, our 28-room hotel dates to 1866. We have hosted a number of famous historical figures including Booker T. Washington and Carrie Nation. The Continental has a restaurant, Lucile's, on the main level that serves lunch and dinner. Free continental breakfast is available here and is included with your stay.

River View Lodge - King Suite 202
Welcome to our luxurious King Suite! This elegant suite features a king-size bed, perfect for a restful night's sleep, and a sofa bed for extra guests. The highlight of the suite is the indulgent jetted tub, where you can unwind and relax after a long day. The large walk-in shower offers a refreshing and invigorating experience. Enjoy entertainment on the flat screen TV and stay connected with free WiFi!

Charming Boutique Country Estate with a pool
No detail is overlooked at this charming and upscale country estate to stay. We have an indoor pool, outdoor basketball courts and pickleball courts, Trager grills available for guests use, outdoor dining area. Plenty of space for your furry friends, we're pet friendly and sit on 10 acres right on the edge of Waverly. Outdoor dog park, book your stay today.

King Suite - Dodici Night Suites
Above the famous Dodici Cafe Restaurant in beautiful downtown Washington, This suite is newly built in 2016. King size bed with sitting area and bath Extra bedroom with queen size bed Other Amenities: Private Bath with Hair Dryer and Bath Products, Air-conditioning, Refrigerator, Microwave, Coffee Maker, Dining Table, TV, Free Wi-Fi

The Monticello Motel
A boutique 1950’s roadside motel offering upscale amenities like premium snack trays. Including common areas that are ready to unwind in with your friends and family. Rent the entire property for your next small gathering or girls trip. This hip spot offers more than just distinctive decor. It’s unlike any motel you’ve never stayed at before!

Lakeside Inn - Clear Lake - Standard King
Charming king room at the newly renovated Lakeside Inn in Clear Lake, IA. In addition to the brand new renovations, you'll also enjoy a one of a kind view of the gorgeous lake. Offering an array of rooms, some with patios, we are here to make your stay an experience to remember.

Lakeside Inn Clear Lake, IA Queen Obstructed View
Pleasant double queen room at the newly renovated Lakeside Inn in Clear Lake, IA. In addition to the brand new renovations, you'll also enjoy a one of a kind view of the gorgeous lake. This room does have an obstructed view of the lake from the room.

Welcoming Suite Near Coca-Cola Museum – 7 Min Walk
Located off Highway 6, explore downtown Iowa and Atlantic Coca-Cola Museum. Perfect for business travelers near Iowa Western Community College. You’ll also find yourself close to Walmart, restaurants, and gas stations.
Popular amenities for boutique hotel rentals in Iowa
Family-friendly boutique hotel rentals

4 Inviting Rooms Near Lake Anita State Park

Unique Stays by the Missouri River, Wild West XP

Easy Highway 6 Access from 2 Suites w/ Breakfast

Deluxe 2 Double, Parking, Stoney Creek Johnston

Expanded King Bunk Bed Suite, Stoney Creek

BBQ & Relax at Comfy Room just off Highway 6

Convenient Room Near Downtown - Bkf Included

Family-Friendly Sioux City Stay, 2 Pools | 3 Units
Other boutique hotel holiday rentals

Romantic Rustic Suites: Fireplaces & Whirlpools

Theme Suite w/ Whirlpool & Fireplace, Stoney Creek

Unwind in Style: Pool, Gym & Free Hot Breakfast

Spacious Rooms: Near Wells Fargo & Art Center

Bringing the Crew? Spacious Room w/ Bkf Included

Rustic Retreat w/ Heated Pool, near I-35 | 3 Units

Your Cozy Johnston Base: I-35 Access | 2 Units

Relaxing Stay! Pool, Free Parking, Pets Allowed!
Destinations to explore
- Rentals with a fireplace Iowa
- Bed and breakfasts Iowa
- Villa rentals Iowa
- Apartment rentals Iowa
- Rentals with a firepit Iowa
- Rentals with outdoor seating Iowa
- Waterfront rentals Iowa
- Barn rentals Iowa
- Flat rentals Iowa
- Smoking-friendly rentals Iowa
- Beachfront rentals Iowa
- Hotel rentals Iowa
- Rentals with an EV charger Iowa
- Townhouse rentals Iowa
- Loft rentals Iowa
- Rentals with a hot tub Iowa
- Cabin rentals Iowa
- Rentals with a patio Iowa
- Cottage rentals Iowa
- Family-friendly rentals Iowa
- Serviced apartment rentals Iowa
- Rentals with beach access Iowa
- Farm stay rentals Iowa
- Rentals with an accessible-height toilet Iowa
- Rentals with pools Iowa
- Tiny house rentals Iowa
- Rentals with lake access Iowa
- Rentals with a washing machine and dryer Iowa
- Lakehouse rentals Iowa
- Pet-friendly rentals Iowa
- House rentals Iowa
- Holiday home rentals Iowa
- Private suite rentals Iowa
- Rentals with a cinema Iowa
- Rentals with breakfast Iowa
- Rentals with a kayak Iowa
- Mansion rentals Iowa
- Campsite rentals Iowa
- Motorhome rentals Iowa
- Guest house rentals Iowa
- Fitness-friendly rentals Iowa
- Boutique hotel rentals United States