Hotel holiday rentals in Middlesex County

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Top-rated hotel rentals in Middlesex County

Guests agree: these hotel rentals are highly rated for location, cleanliness and more.

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Superhost

Hotel room in Boston

5 out of 5 average rating, 3 reviews

Timeless Stay | Freedom Trail. Fitness Center

Explore a beautifully reimagined luxury hotel, The Newbury Boston, where the bustle of the Back Bay is your playground and the idyllic Boston Public Garden your front yard. Attractions just nearby: ✔Boston Expressionist paintings and Chinese ceramics at Museum of Fine Arts ✔Deep dive into history at Boston’s Tea Party Museum ✔Sharks, rays, penguins at New England Aquarium ✔400 years of Boston’s history and the story of nation’s pursuit of liberty, Freedom Trail ✔Downtown Boston

Guest favourite

Hotel room in Natick

4.96 out of 5 average rating, 26 reviews

Close to campuses & large mall with dining options

The Residence Inn Natick is the perfect location for guests visiting both Natick, Framingham and Newton. Close to area colleges and universities, our hotel is centrally located just minutes outside Boston. - Walking distance to Natick Mall, PuttShack and many restaurants. - Nearby to Logan Express with express bus service to Logan Airport - Free Breakfast Buffet - Hand-Crafted Cocktails in our Lobby and Lounge - Electric car charging stations - Fitness Room - Full kitchen in each room

Superhost

Private room in Cambridge

4.74 out of 5 average rating, 245 reviews

Charming, peaceful rm, walk to Harvard/MIT/Central

This quiet, peaceful room in Inman Square is a great choice for your next trip to Cambridge/Boston. It is centrally located—a 10-to-15-minute walk to Harvard, MIT, Central Square, and the tech companies around Kendall Square. Whole Foods, Koreana, S&S Deli, local microbreweries, and many more food options are within blocks. This private room shares a bathroom with one other room. Access to the kitchen and deck and also included. An economical “get away” in the heart of Cambridge.

Superhost

Hotel room in Lexington

4.81 out of 5 average rating, 116 reviews

Near Hanscom AFB + Free Breakfast. Kitchen. Pool.

Discover Element Lexington, your eco-chic launchpad just minutes from historic Battle Green and Minuteman National Park. Wake up to a free hot breakfast, then bike the nearby scenic trails or explore Lexington’s charming shops and cafes. Unwind in spacious suites with full kitchens, splash in the indoor saltwater pool, and recharge in the 24-hour fitness center. With free parking, pet-friendly rooms, and Boston only a short drive away, it’s the perfect New England getaway base.

Guest favourite

Hotel room in Boston

4.89 out of 5 average rating, 9 reviews

Steps from Fenway Park + Free Breakfast & Pool

Stay steps from Fenway Park in a hotel that lives and breathes rock ‘n’ roll. At The Verb, you’re not just checking into a room—you’re stepping into a retro-cool experience with a vinyl library, record players in every room, and a year-round outdoor pool. Whether you’re catching a game, exploring Boston’s iconic music scene, or sipping cocktails poolside, this stay is anything but ordinary. It’s fun, loud (in a good way), and full of personality—just like the city around it.

Top guest favourite

Hotel room in Newton

5 out of 5 average rating, 86 reviews

Inn at Newton Highlands, Suite 1, Apartment-Hotel

This gorgeous 2 bedroom, 2 1/2 bathroom suite at The Inn at Newton Highlands is pure luxury. It features a large and inviting living room, spacious bedrooms with private bathrooms, a private 500 sq.ft. deck, and everything else to make your stay comfortable and memorable. The suite has its own HVAC system. This suite is one of several luxury suites in a small boutique Inn which is located in the heart of Newton Highlands in a beautiful, fully remodeled historic building.

Superhost

Hotel room in Cambridge

4.78 out of 5 average rating, 201 reviews

Steps from the T & Museum of Science

The Fairfield Inn and Suites Cambridge is the perfect location for guests visiting both Cambridge and Boston. Close to MIT and Harvard Universities, the TD Garden and a short walk to the T for subway rides into Downtown Boston. - 24/7 Front Desk support - Free Wi-Fi - Free breakfast buffet daily - Housekeeping service - Mini-refridgerator/Microwave/Private Bathroom in each room - Market on-property for anything you forgot or need - Fitness Room - Parking (daily fee)

Superhost

Hotel room in Boston

4.83 out of 5 average rating, 12 reviews

Lively spot near the Children’s Museum & more

Whether you're traveling far or planning the staycation of a lifetime, make it count at The Westin Boston Seaport District. A vibrant neighborhood in an iconic city, the Seaport District offers rich history, world-famous attractions, and hidden gems for those who want to take the path less traveled. We are close to family-friendly fun at Boston Children's Museum, stunning exhibits at the Institute of Contemporary Art, and much more.

Superhost

Casa particular in Medford

4.65 out of 5 average rating, 17 reviews

Become a part of Boston’s rich history!

Welcome to a little piece of history! This condo is located on the road of Paul Revere’s famous ride. Housed in an 1800s building with stone walls, this cozy retreat blends old-world charm with modern comfort. Enjoy a living room with original hardwood floors, a fully equipped kitchen with marble countertops, and two inviting bedrooms. The condo is near public transit, allowing quick access to Boston and Cambridge in mere minutes!

Superhost

Hotel room in Boston

4.81 out of 5 average rating, 99 reviews

Great central location in Downtown Boston

The Residence Inn Roxbury South End is the perfect location for guests visiting Boston. Close to area colleges, universities, and hospitals including Mass General, our location makes it easy to explore Boston. - Walking distance to restaurants and shopping - Free Breakfast Buffet - Hand-Crafted Cocktails nightly in our lobby lounge - Valet Parking available (nightly fee applies) - Fitness Room - Full kitchen in each room

Superhost

Hotel room in Chelsea

4.83 out of 5 average rating, 143 reviews

Guest Room with King Bed at Chelsea

Welcome to Boston Logan Airport Chelsea Find us off U.S. Route 1 and Massachusetts State Hwy 16. We’re across the street from Mystic Mall and a half mile from Apollinaire Theater Company. We’re just three miles from Bunker Hill Monument and Boston Logan International Airport BOS. Our airport shuttle runs Daily Sunday-Saturday. Enjoy complimentary hot breakfast, WiFi.

Superhost

Hotel room in Boston

4.86 out of 5 average rating, 152 reviews

Harborside Inn-Boutique Hotel

Originally built in 1846 as a mercantile shipping warehouse on the Boston Harbor. Here, a modern design with a nautical theme is accented with the latest high technology amenities to satisfy the most savvy business or leisure traveler. Premier location. Exceptional value. Stylish decor. The Harborside Inn combines it all to create a unique lodging experience.