Places to stay near Museum of Life and Science

Book unique holiday rentals, homes and more on Airbnb

Top-rated holiday rentals near Museum of Life and Science

Guests agree: these stays are highly rated for location, cleanliness and more.

1 of 1 pages1 / 1
Top guest favourite
Guest house in Durham
4.96 out of 5 average rating, 385 reviews

Modern Cottage With a Vintage Twist Near Downtown

Come stay at our modern vintage guesthouse in Historic Trinity Park. Our cottage has all modern appliances with vintage fixtures. Our cottage is a cozy, lived-in retreat with rustic charm. This 380 square foot cottage is located in a very lively and safe neighborhood just minutes from downtown Durham. Walk one mile on the Ellerbe creek trail to downtown! Walk 1.5 mile to 9th street restaurants and shops 1 mile to Central Park and farmers market <1 mile to bars and restaurants on geer street

Top guest favourite
A vibrant garden entrance is framed by an arch covered in bright yellow flowers. Lush greenery surrounds a winding pathway, leading toward trees adorned with soft pink blooms and scattered outdoor seating beneath umbrellas. The scene evokes a serene outdoor retreat.
Flat in Durham
4.98 out of 5 average rating, 1,153 reviews

2-BR apt/garden near downtown Durham arts & eats

A private, restful & artful 2-BR apt. hosted by one of fewer-than-20 Airbnb Belo Award winners in the world. 900 sq. ft. complete lower fl. of 1960s brick split-level on unpaved lane near park. Lush garden. Private entry; parking; lvng rm w/fireplace; bthrm/shwr; kitchenette only; generous amenities; wifi; TV. Superhost since 2014; 1,100+ 5-star reviews. 1 mi. DPAC/Durham Bulls; 1.5 mi. Carolina Theatre; 3 mi. Duke U/Med Cntr. No added cleaning fee. The dear furry ones do not enter the apt.

Guest favourite
Home in Durham
4.9 out of 5 average rating, 243 reviews

Family Visit+Pet+Fenced+DownTown+FibreWiFi.

- Sparkling clean, quiet, single level duplex. No steps. No shared spaces. - Ideal for work and medical stays near Duke and the VA. - 1 gig Wifi- AT&T. -Children ready - Pack N Play, eating ware, puzzles, books. - Separate fenced yard. Pet friendly. - Well stocked kitchen. -Washer and dryer. -Bathroom- bathtub, grab bars, wonderful shower. - Work desk. - Comfortable beds. - 2 Blocks to Ellerbee Creek Trail. - Close to downtown. See maps. - One parking space in front of unit.

Top guest favourite
Tiny home in Durham
4.97 out of 5 average rating, 393 reviews

Tiny Farmhouse in the Heart of Durham

Enjoy the tiny experience without sacrificing the relaxations and comforts of home. Unwind in this quaint 1 bedroom 1 bath tiny farmhouse that’s equipped with full-sized appliances and tasteful amenities. The Farmhouse at Scout is nestled in Downtown Durham’s burgeoning Southside neighborhood and is extremely close to the best restaurants, shops, and activities that Durham has to offer. Major attractions: • DPAC: .8 mi • Durham Bulls: .8 mi • Farmer’s Market: 1.2 mi • Duke: 2.9 mi

Guest favourite
The studio's private entry is framed by a white wall. A sleek glass door is flanked by two modern outdoor light fixtures. A small seating area with a cushioned chair is visible to the left, while a sheer curtain adorns the adjacent window.
Guest suite in Durham
4.88 out of 5 average rating, 156 reviews

Private studio apartment steps from Downtown!

Compact studio steps from Downtown Durham with a private entry and free street parking! Well-stocked kitchenette and bathroom. Close to Duke and walkable to all of Downtown and more: ✦ 7+ coffee shops ✦ 10+ breweries ✦ Plenty of restaurants + bars ✦ DPAC, Durham Bulls + Durham Convention Center ✦ Central Park, Farmer's Market + Durham Food Hall ✦ Ellerbe Creek + American Tobacco Trails We live in the townhouse above the studio and are happy to assist with anything you might need.

Top guest favourite
A spacious living area features large windows allowing natural light to fill the room. A round dining table sits in the foreground, while a sectional sofa and comfortable chairs create a relaxed seating arrangement. A sense of openness is enhanced by high ceilings and wooden flooring.
Flat in Durham
5 out of 5 average rating, 121 reviews

Downtown Durham Retreat

You’ll love this impeccable private downtown Durham apartment for the location, the views, the high ceilings & the luxurious master bedroom. 3rd floor unit in a renovated historic building. 3 blocks from Durham Performing Arts Center, Durham Bulls Athletic Park & the Amtrak station. 8 minute walk to Duke University West campus. Situated in the heart of the foodie paradise that IS downtown Durham. Ideal for 1-4 guests, business travelers, long-term stays welcome (kids 12+ please).

Guest favourite
The dome structure is illuminated from within, showcasing a cozy interior with wooden accents and soft linens. The exterior design features a geometric pattern of clear panels, allowing glimpses of the interior and the surrounding trees in the evening light.
Dome in Durham
4.97 out of 5 average rating, 315 reviews

The Japandi Dome

Experience a taste of Japandi in this dome home on our small homestead, and enjoy the mind and body benefits of being closer to nature with the comforts of indoor amenities. This unique space is built with a full skylight to allow you to sleep under the night sky. Complete with heating and A/C for year-round comfort, a full zen-inspired bathroom, and luxury European bedding. Enjoy your meal around a Japanese inspired floor table with straw mats and meditation cushion for seating.

Guest favourite
Flat in Durham
4.84 out of 5 average rating, 150 reviews

Apartment in leafy Colonial Village, Durham

I turned my house into a duplex, by turning a very 70s addition into a private, cozy, and charming space. There's a kitchenette, a dining area, and a sitting area, a bedroom, and a bathroom. The location would be ideal for someone who needs quick access to Duke Regional Hospital (4 minutes away) or downtown (6 minutes), or someone who wants to keep up a running habit (the greenway is nearby). A taqueria, a grocery store, and a coffee shop are within walking distance.

Top guest favourite
A tiny house is depicted, featuring a bright blue exterior and a welcoming wooden deck. Surrounding trees provide shade, and a stone walkway leads to the entrance. The setting is lush with greenery, enhancing the serene atmosphere of the backyard escape.
Tiny home in Durham
4.96 out of 5 average rating, 311 reviews

Five & Dime Tiny House

Experience the charm of tiny living in this pet-friendly studio located in my serene yet urban backyard. It offers a peaceful escape while remaining convenient to the attractions & amenities that Durham has to offer. -only a mile east of downtown -1.5 miles to DPAC and Carolina Theatre -ten minutes to both Duke Hospital and Duke Regional -less than 20 minutes to RDU airport Let your dog run around the fully fenced yard while you sit on the deck and sip your coffee!

Top guest favourite
Bungalow in Durham
4.91 out of 5 average rating, 381 reviews

Cheerful 50s Cottage Near Duke

This charming 1950s two-bedroom 800-square-foot cottage is located just north of Duke’s East Campus in Durham’s Walltown neighborhood. The home sleeps up to four adults with two queen beds, offers keyless entry, and includes high-speed internet. Inside, you’ll find a bright, renovated space with a modern kitchen, colorful artwork, and a bathroom with a small soaking tub. Outside, a short set of steps leads to a large, fenced backyard shaded by mature oak trees.

Top guest favourite
Tiny home in Durham
4.99 out of 5 average rating, 116 reviews

Rivers Edge Farm Silo Suite

Enjoy the sounds of nature when you stay in this unique place. The Silo Suite tiny home is nestled in a private area by the silo on our horse farm. This location is fully equipped with all the comforts of home. Loads of day hiking opportunities whether your planning a day trip, weekend getaway or week long vacation there is no shortage of things to do and see. Come enjoy our country setting that’s only minutes away from Duke and Downtown.

Top guest favourite
Guest suite in Durham
4.95 out of 5 average rating, 254 reviews

The Mural Suite, An Artsy One Bedroom in Durham

A mural filled one bedroom suite with a full bath and kitchenette attached to our house with its own separate entrance. Located less than 5 minutes by car to downtown Durham with easy access for those who prefer to travel by bicycle or foot to the Ellerbee Creek trail. Centrally located to Duke University and Duke Medical. Perfect for longer stays for visiting professionals as well as shorter stays to enjoy all Durham has to offer.

Popular amenities for holiday rentals near Museum of Life and Science