Holiday rentals in Osborn Medical Center, Phoenix

Best Little Guesthouse in Melrose !

Historic guesthouse in the heart of the Melrose District! EV charger! Walking distance to restaurants, bars, coffee shops, the famous Melrose Vintage shops, grocery stores, LA Fitness and more! Want to head downtown to Chase Field, Talking Stick Arena for a game or a show? Campbell Street Light Rail station is only five short blocks away! No need for a car, you can take the Light Rail from Sky Harbor International Airport, save your money for entertainment! Off street parking if you have a car!

Spacious Midtown guesthouse with full privacy

Welcome to your private casita (tiny home) in the heart of Midtown. Located right across the street from Starbucks, Buffalo Exchange, and the famous Taco Guild, relax comfortably with vaulted ceilings, a spacious layout, outdoor patio, and a quiet bedroom with a Queen-size bed — perfect for solo travelers or couples. Plus, the Light Rail station is walkable, which goes to Uptown, Downtown, the airport, Tempe, and Mesa. You are only: 7 mins to Downtown 9 mins to the Airport 15 mins to Scottsdale

Stunning Historic Adobe in Central Phoenix!

Beautiful, bright, airy, mid-century adobe casita, located and overlooking a walled tropical garden in historic central Phoenix. 10 min from Sky Harbor Airport and located in the very popular and historic Melrose District. 20 restaurants, bars, cafes within 3 blocks walking distance. Wine shops, vintage stores, grocery, and pharmacy within 2 blocks walk. Scottsdale/Downtown Phoenix a very short drive. Furnished with antiques and regional artwork. Wifi, TV, full kitchen, washer/dryer included.

PHX's Modern Midtown Carriage House, Free Parking

Experience the perfect blend of historic charm and modern comfort in the heart of Phoenix's Midtown. Our beautifully designed Carriage House offers a unique guest quarters, complete with a full kitchen, luxurious queen bedding, and a private patio. Step outside and explore the vibrant neighborhood, filled with local restaurants, shops, and cultural attractions. Book your stay at the Midtown Carriage House today and discover the best of Phoenix living. check out on insta @midtowncarriagehouse

Private, Sparkling Clean Historic DTPHX Guesthouse

This charming studio guesthouse in the Campus Vista historic district is a fantastic find! Situated in a friendly neighborhood in the heart of Phoenix, this newly remodeled living space is cozy and practical, surpassing many of the similar properties in quality and character. A short ten-minute drive from the Sky Harbor Airport, and located within walking distance to two major bus lines and the light rail, the guests are sure to enjoy the easy access to all the popular downtown destinations.

Private, desert-chic casita in vibrant Midtown PHX

Welcome to Casita Amelia, a modern rustic retreat central to all the action Phoenix has to offer. Welcoming and cozy, this newly updated private guest suite has all the luxuries of a modern hotel suite while being quietly tucked away in a cute Midtown neighborhood. Walk to Melrose District. You're also just 5-10 mins by car to Uptown & Camelback Corridor, 10 mins to Downtown (Footprint Center, Chase Field, Arizona Financial), 15 mins to Sky Harbor Airport, and 20 mins to State Farm Stadium.

Historic Cottage! Walk to Restaurants & Nightlife

Welcome to Melrose Cottage, a 1937 historic gem with timeless charm and a playful pink accents . Nestled in Phoenix’s vibrant Melrose District, you’ll be steps from top-rated restaurants and bars like Across the Pond and Clever Koi. Inside, enjoy original oak floors, arched walkways, and a spacious backyard perfect for relaxing. Lovingly cared for over the decades, Melrose Cottage combines vintage character with an unbeatable location in one of Phoenix’s most culturally rich neighborhoods.

Private Casita w/ Pool* & BBQ in Historic Melrose

*PLEASE READ HOUSE RULES IN "OTHER THINGS TO NOTE" AREA BEFORE BOOKING* Under no circumstance can one book the Airbnb for another guest . This violates our house rules as well as Airbnb policy. Read more under HOUSE RULES for more details. Our cozy casita is located in the Woodlawn Park neighborhood, a short car ride from the Melrose and Willo Districts. Located near some of the best restaurants in Phoenix, this is the perfect stay for visitors who want to explore the local food scene.

Converted 30s Historic Carriage House in Del Norte

Reliably operated by a top AZ Superhost with 4,400+ 5 star stays. Del Norte - the only historic district near downtown Phoenix to be surrounded by 3 green parks. This is a converted 1930’s carriage house (next to an English Revival Cottage) that was carefully curated with your rest and peace in mind. Exclusive designer finishes, with full functionality - fully stocked mini-kitchen, spa like bathroom. Patio seating in the shade to enjoy the AZ inside / outside living. INCLUDED 👇

Private studio cottage, charming, downtown

This is a 100 year old quaint historic home located in downtown Phoenix area. Encanto Park established in 1935 is right across the street, enjoy the duck ponds, paddle boating, 18 hole Encanto golf course within walking distance, Pool directly across the street during summer only. friendly park and neighborhood! Bikes are available for borrowing. Several restaurants, museum, theatre within 2 miles. Sky Harbor Airport within 7 miles, Highway I17, I10 within 2 miles.

The Beverly Bungalow | Stylish Stay Near Downtown

Relax & unwind at our mid-century bungalow in the heart of Phoenix. This 1BR/1BA condo will comfortably sleep 2. Our condo is complete with a full kitchen, cozy living room & dedicated work space for the WFH professional. Also included is a shared pool/hot tub to cool off on those hot summer days. Located in Midtown center to museums, unique bar & restaurant concepts, Chase Field, The Footprint Center - the list goes on. We hope you enjoy all AZ has to offer!

Marta's Cozy Brick Home in Midtown PHX

Centrally located condo in a beautiful neighborhood with detached carport. Completely renovated and tastefully decorated. Cleaned following the guidelines recommendations from the CDC to prevent spread of COVID-19 and with HEPA air purifier. Cozy Tuft and Needle beds and fully equipped kitchen. Private patios. In walking distance to a variety of restaurants and The Valley Metro Light Rail. City of Phoenix Short-Term Rental Operating Permit # STR-2025-000722