
Holiday rentals in Panama Bay
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Top-rated holiday rentals in Panama Bay
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CASA SAEMA -PRESTIGIOUS DUPLEX PENTHOUSE WITH TERRACES
Spectacular duplex penthouse in Panama's Casco Antiguo, 265 m2 with balconies, private outdoor terraces, an indoor garden lounge, a dining room, 3 bedrooms (+ sofa bed in the studio), recently renovated with a loft concept, exclusive, unique, and comfortable design, in the best area of the Casco Viejo, perfect for relaxing and unwinding, kitchen, dishwasher, living room with washing machine, shared pool, elevator, 24/7 doorman, children who cannot swim are not allowed, wide variety of leisure activities in the area.
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Casa Condal - Your Luxury Retreat in Cerro Azul
Birdwatching • Romantic Getaway • Remote Work Escape the city. Breathe pure mountain air. Reconnect with nature. Casa Condal - private, modern, sustainable and regenerative hospitality inside Chagres National Park WiFi 65" Smart TV. Sound Bar Self check-in Private parking Fully equipped kitchen 220mts. private trail Deck-Mirador + FirePit, panoramic view of the mountains and valley King bed + Full size sofa bed BBQ Wheelchair accessible 40 min from Tocumen Airport. 1 hr from Panama city.
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The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife
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Patty’s Casco 2BR Loft | Balcony & Personal Touch
“Feel at home in Casco Viejo—personally welcomed by your hosts, Patty & Rudy.” Stay in the Heart of Casco Viejo with Patty’s Casitas! Prime Casco Viejo Location | Quiet, Convenient & Charming Stay steps from restaurants, cafés, bars, and plazas—right by the El Rey boutique supermarket and the waterfront promenade. This peaceful spot is rare in Casco, tucked away from rooftop noise and perfectly located at the entrance of the neighborhood for easy in & out access!
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Casa Rosie - Dream Home on Tabogá Island
Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.
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Walk to Everything | Luxury Stay in Casco Viej
Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.
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Casco Antiguo Apartment with Balcony & Stone Wall
Elegant apartment in the heart of the Historic District. Enjoy a colonial-style space with exposed stone walls, warm lighting, and a charming balcony overlooking vibrant streets. Located on Avenida B, within walking distance of restaurants, coffee shops, rooftop bars, and historic sites. Sleeps up to 5 guests. Perfect for experiencing the culture and energy of Casco Viejo. Due to the lively atmosphere in the area, noise may be heard at night on weekends.
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The Crystal House: Luxury Modern Wood Cabin
Create unforgettable memories at this unique and family-friendly place. Stay in a cabin in the middle of Chagres National Park, 50 minutes from the city. You can be in contact with nature while having all the comforts of a luxury accommodation. With one of the best views of the city, you can enjoy a good barbecue, a nap in the hammock, or a meeting around the fireplace. Relax and connect with the beautiful green of Panama. We'll be waiting for you!
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Tropical Haven with Pickleball/Yoga Platform
Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.
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Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.
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Most Beautiful Loft in the Heart of Casco Viejo
Discover Casco Viejo from this beautiful loft, perfectly located. Casco Viejo, UNESCO World Heritage Site, known for its colonial buildings, and iconic streets. This vibrant neighborhood offers many restaurants, coffee places, museums, and an exciting night life. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.
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The best view of the Old Town
Welcome to this charming accommodation in the heart of the Casco Viejo, located on the third floor facing one of Panama's most iconic squares, Plaza Catedral! Thanks to its prime location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have a wide variety of restaurants and shops at your disposal where you can buy souvenirs of this wonderful trip.
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Popular amenities for Panama Bay holiday rentals
Other great holiday rentals in Panama Bay

Luxury Centric 2BR Apartment in Casco Viejo
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Cerro Azul Mountain Retreat a magical home.
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Mountain Retreat
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Gorgeous Flat in the best location in Casco Viejo
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Luxury Apartment | Walk to Restaurants & Shops
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Saboga: El Remanso Beachfront Entire Upper Level
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Peaceful Stay in the Heart of Casco
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Ocean Front House on exclusive Contadora Island
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