
Holiday rentals in Panama
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Panama
Guests agree: these stays are highly rated for location, cleanliness and more.

FACING THE SEA Cacique (Portobello Park)
Une maison ! véritable îlot de verre au cœur de la jungle ! Au beau milieu du Parque National de Portobello (accès uniquement en 4x4 AWD) blotti au sommet de la colline, entre ciel/mer, à l'abri de tout regard, une maison transparente où le verre épouse la nature de tous côtés créant une connexion unique entre l'intérieur et l'extérieur, ideal pour se reposer, se déconnecter, confortable, spacieuse, fraîche (clim centrale), exclusive. Elle est le témoin d'un spectacle grandiose qui vous attend !

Beach House-Amazing Pool & Jacuzzi - Pet Friendly
Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Torio guesthouse with panoramic view; Kokomo
Our private guesthouse is suspended over the Torio River, on the west coast of the Azuero Peninsula. It is a paradise for hikers, bird watchers, surfers and beach goers. Marked trails with posted maps begin at our place. Hike to a beautiful waterfall, mountain or beach. Photograph birds from the porch. Surf, body board and swim safely (no strong currents). Walk to good restaurants, and a small grocery. Experienced Surfers have Morrillo Beach and Playa Reina. Watch sun and moon rise.

Beachfront Gem w/ Ocean Views & Prime Surf Access
Welcome to your slice of beachfront paradise! Our home sits right on Cambutal's beautiful shoreline. Gorgeous ocean views greet you from every window, while the gentle rhythm of waves creates the perfect soundtrack for your stay. We've equipped the house with Starlink WiFi and a large dining table that doubles as an ideal workspace, making this a perfect retreat for both vacationers and remote workers. The house feels like a real home – comfortable, clean, and ready for your beach memories.

Casitas in Butterfly and Honey Farm
Romantic setting, immersed in nature and yet close to town. Fibre Optic Internet. Nestled in extensive tropical gardens on a traditional Boquete Coffee Estate. Abundance of birds, feeders and native bee hives. We are home to Panamas largest butterfly exhibit and specialty honey company. We offer a hearty breakfast. We can accommodate 4 px but booking price including breakfast is for 2px. We charge an additional $15 per person over 12 yrs, an additional $10 for children under 12 yrs

Pebos Reef, apt #2, Amazing views !!
This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.

Pedasí, Los Destiladeros Beach / Casa Serena
❤ Welcome to Casa Serena, escape to our stunning 3-bedroom ocean view house, perfectly located in Playa Los Destiladeros, an area of beautiful beaches in Pedasí. This unique retreat offers a blend of modern luxury and coastal charm, ensuring an unforgettable vacation experience for you and your loved ones. Book your stay today and experience the magic of Casa Serena. Create lasting memories with your family and friends in this perfect ocean view escape.

Casa Samambaia - sea view tropical paradise w pool
With a modern tropical design, this home features a cozy living room and a stylish kitchen at the center of the social area. Open the glass doors to immerse yourself in open-concept living, seamlessly blending the indoors with the main terrace and the pool, all oriented towards the ocean view. With two en-suite bedrooms with AC and fans, the house is immersed in nature, green mountains, and a lovely garden, everything 5 minutes from the beach center.

Mountain retreat
Our beautiful, modern, comfortable house is designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and also a base to explore the area which is in a beautiful part of Panama near a cloud forest national park with amazing hiking to waterfalls and local communities. The house is large, sleeping 12, within 17 acres of forest with rivers for swimming. We can arrange tours and hosted retreats for yoga, cooking and more.

Cocovivo Mangrove Treehouse
This secluded loft-style treehouse sits on stilts above the water, 30 feet from our colorful coral reef. Transparent and airy but bug proof walls let you enjoy the fresh ocean breeze and views while keeping you safe and cozy. When a sloth comes to visit, no need to leave the house to see him! Blend in with the surroundings of mangrove, lagoon and jungle, and enjoy water and reef access from your own deck. Bright and airy, 100% eco-conscious.

Casa De Ola, Jungle Beach Cabin
Welcome to Paradise: Your Pacific Jungle Oasis Nestled deep within the lush, untamed heart of Panama's wild Pacific coast, this remote jungle cabin isn't just a place to stay—it's an invitation to experience life at its most primal and extraordinary. It is a destination by itself. This is your passport to a world where nature reigns supreme, adventure lurks around every emerald-green corner, and artistry dances with the elements.

Overwater Cabin#1 on Misdub: Meals & Tour included
🌴✨ Discover the Secluded Charm of Misdub Island 🛖 Overwater Cabin 👥 Minimum 2 guests or $20 extra fee per night for solo travelers. Capacity 2 guests, book a second cabin if needed. Welcome to Misdub Island, the sister island of Yani Island, nestled in the Lemon Keys. This secluded paradise is surrounded by pristine turquoise waters, offering unparalleled exclusivity and tranquility far from the crowds of day tours.
Popular amenities for Panama holiday rentals
Other great holiday rentals in Panama

Casa del Mar - eco aqua villa

Entire Villa with pool in front of beach!

Elegant apartment with a view & the warmth of home

King Bed, Creative Design Steps from Casco Viejo

Luxury Jungle Villa

Jane’s Treehouse~ Charming 1bed/1bath treehouse

Luxury apartment in the Panamá city

A Remote Paradise in nature - Ocean View
Destinations to explore
- Tent rentals Panama
- Bungalow rentals Panama
- Nature eco lodge rentals Panama
- Earth house rentals Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Rentals with beach access Panama
- Boutique hotels Panama
- Rentals with a patio Panama
- Chalet rentals Panama
- Rentals with breakfast Panama
- Rentals with a cinema Panama
- Boat rentals Panama
- Lakehouse rentals Panama
- Fitness-friendly rentals Panama
- Rentals with a fireplace Panama
- Container rentals Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Rentals with a sauna Panama
- Beach apartment rentals Panama
- Rentals with a firepit Panama
- Rentals with an accessible-height bed Panama
- Townhouse rentals Panama
- Tiny house rentals Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Cottage rentals Panama
- Treehouse rentals Panama
- Smoking-friendly rentals Panama
- Rentals with a hot tub Panama
- Loft rentals Panama
- Island rentals Panama
- Dome rentals Panama
- Villa rentals Panama
- Family-friendly rentals Panama
- Aparthotel rentals Panama
- Hotel rooms Panama
- Waterfront rentals Panama
- Guest house rentals Panama
- Rentals with a washing machine and dryer Panama
- Holiday home rentals Panama
- House rentals Panama
- Apartment rentals Panama
- Bed and breakfasts Panama
- Farm stay rentals Panama
- Rentals with pools Panama
- Beach house rentals Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Rentals with lake access Panama
- Pet-friendly rentals Panama
- Flat rentals Panama




