
Apartment holiday rentals in Panama Canal
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Top-rated apartment rentals in Panama Canal
Guests agree: these apartments are highly rated for location, cleanliness and more.

In the heart of Casco, refurbished and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen
4.96 out of 5 average rating, 263 reviews
Luxury Oceanfront Resort 22nd Floor View, 200°
Luxury oceanfront apartment on the 22nd floor with breathtaking panoramic views of Panama Bay, the skyline, and historic Casco Antiguo. Located on the famous Cinta Costera, this resort-style apartment offers 2 bedrooms, 2 bathrooms, luxury kitchen, 65” TVs, washer/dryer, and sleeps up to 6 guests. Enjoy spectacular sunsets from the balcony and access to infinity pool, gym, and premium amenities, just minutes from restaurants, nightlife, and Panama City’s top attractions.
4.85 out of 5 average rating, 73 reviews
Stunning Terrace Among Ruins in Casco Viejo
Welcome to your Casco Viejo retreat! This spacious apartment, perfect for up to 8 guests, offers a unique blend of modern comfort and historic charm in Panama City’s most iconic neighborhood. Located in the heart of Casco Viejo. The highlight of this beautiful space is the stunning terrace nestled among historic ruins, where you can relax, enjoy a meal, or simply take in the timeless atmosphere. This is more than a stay – it’s an unforgettable experience.
4.82 out of 5 average rating, 143 reviews
Ocean View | Rooftop Pool | Luxury Stay
Wake up to a stunning ocean view right from your window at BrisaMarina. This luxury apartment is located in the spectacular The Sands building, right on the Cinta Costera. The modern and cozy space features bright natural light, air conditioning, high-speed Wi-Fi, and a fully equipped kitchen for your comfort. You’ll be just minutes away from restaurants, beaches, and top attractions. Perfect for couples, business travelers, or weekend getaways.
4.97 out of 5 average rating, 97 reviews
Apartment in the Causeway Amador
Forget your worries in this spacious and serene space. Where you can enjoy the views of the Panama Canal and see the boats that pass through it, a space full of amenities with a perfect location, you can walk through the streets of the Causeway, visit the Biodiversity Museum, restaurants of various specialties, amusement park, bike rides etc, everything comes together to make this vacation an unforgettable experience for your whole family
4.75 out of 5 average rating, 122 reviews
Amazing experience 3BR 2BTH Casco Viejo w/Rooftop
Enjoy Panamanian culture from the center of Casco Viejo, where you'll discover colonial architecture, visit the area's best restaurants, nightspots, and rooftops. Quiet and comfortable apartment. Features a living room, dining room, equipped kitchen, work desk, 2 queen beds, 1 twin bed, 2 bathrooms, closets, air conditioning, balcony, barbecue, and outdoor dining area. We offer everything you need to have the best local experience!
4.8 out of 5 average rating, 110 reviews
Luxury apartment in downtown Panama, banking area
We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance
4.92 out of 5 average rating, 178 reviews
Beautiful Apt, Best Location 2BR
Beautiful apartment, high floor up, with 2 bedrooms, 2 bathrooms, walking closet, and essential closet for the second bedroom. Extra twin bed available in the apartment. High speed internet, 300Mbps by Wifi aprox. , 600Mbps by cable. Social area on the roof with swimming pool, gym, sauna and bbq area. The building location is excellent, We are walking distance for grocery stores, restaurants, bank, Hilton Hotel&Casino.
4.89 out of 5 average rating, 196 reviews
Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.
4.97 out of 5 average rating, 166 reviews
Modern, central and comfortable (001)
Modern and cozy studio in the heart of Panama. Perfect for exploring the Old Town, the Coastal Strip and more. Full kitchen, full bed, double sofa bed, air conditioning, fast WiFi and private bathroom. Ideal for 1–4 people. Private access, elevator and self check-in. Surrounded by restaurants, transportation, and tourist sites. Your ideal base to explore the city!
4.87 out of 5 average rating, 148 reviews
PH The Gray | Balcony Views · Pool · Gym
Wake up to panoramic views of Cerro Ancón from your private balcony — right in the heart of Calle 50, Panama’s financial and lifestyle hub. The Gray is a brand-new building offering resort-style amenities: rooftop pool, gym, and a fully equipped coworking space with high-speed Wi-Fi. You’ll also find restaurants and cafés inside the building itself.
4.84 out of 5 average rating, 100 reviews
Nice & Cozy 3-Bedroom Apartment!
Centric Apartment in the Heart of the City! This building is located in El Cangrejo, a centric, friendly neighborhood filled with a variety of restaurants, bars, casinos and shops. Everything you need is within a 5 minute walk. Popular areas such as Casco Viejo, the Panama Canal Locks, Causeway and main shopping malls are within a 10 minute drive.
4.93 out of 5 average rating, 134 reviewsPopular amenities for Panama Canal apartment rentals
Weekly apartment rentals

Old Town & Ocean View
4.9 out of 5 average rating, 72 reviews
Ocean View Suite Coastal Strip
4.79 out of 5 average rating, 34 reviews
Beautiful apartment, oceanfront.
4.81 out of 5 average rating, 83 reviews
Albrook Palms | Apartment + 2 Suites 4BR/4BA
4.94 out of 5 average rating, 17 reviews
Casa del Horno | A Piece of Panamanian History
4.93 out of 5 average rating, 74 reviews
Modern studio with ocean view / downtown / prime location
4.96 out of 5 average rating, 28 reviews
Panamá Pacífico P.H. Centriqo: Close to Everything.
5.0 out of 5 average rating, 33 reviews
Luxury apt in Panama City 3 Rooms 4 baths
4.87 out of 5 average rating, 77 reviewsPrivate apartment rentals

Luxury Stay & Panoramic Bay View in YOO Panama
4.82 out of 5 average rating, 11 reviews
Yoo 28th | Panoramic City View + Large Balcony
5.0 out of 5 average rating, 3 reviews
5B • 5 Bedroom Apt • 4 Baths • Ideal for 10 Guests
4.96 out of 5 average rating, 24 reviews
Unique Luxury 3-story Loft at the Yoo
4.96 out of 5 average rating, 89 reviews
Cozy 1 bedroom apartment near Casco Viejo
4.93 out of 5 average rating, 14 reviews
Spectacular Bay View • 1BR • Pool/Gym and +
4.89 out of 5 average rating, 35 reviews
VIP Suite/Sea View + Pool & Sky Lounge + Gym
4.95 out of 5 average rating, 80 reviews
GreatCanal-Front Luxury 3BR | City & Golf View 401
5.0 out of 5 average rating, 12 reviewsApartment rentals with a hot tub

New Flat with Ocean + City Views
4.78 out of 5 average rating, 125 reviews
Ocean View Apt in Panama, Yoo&Arts
4.8 out of 5 average rating, 145 reviews
Tropical Paradise at Playa Bonita
4.93 out of 5 average rating, 118 reviews
PH Yoo 44i – Ocean View Apartment
4.85 out of 5 average rating, 85 reviews
The Perfect Oceanview Getaway
5.0 out of 5 average rating, 4 reviews
Luxury 2BR Suite with Pool & Views
5.0 out of 5 average rating, 45 reviews
View and Comfort Apartment with Home Warmth
4.88 out of 5 average rating, 26 reviews
Historic 2BR Loft at Casa del Horno, Old Town
4.79 out of 5 average rating, 19 reviewsDestinations to explore
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- Things to do Panama
- Landmarks Panama
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- Outdoors Panama
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