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Mansion holiday rentals in Panama

Find and book unique mansions on Airbnb

Top-rated mansion rentals in Panama

Guests agree: these mansions are highly rated for location, cleanliness and more.

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Guest favourite
A private plunge pool sits beside a wooden deck, framed by a blue shade sail. The warm wooden tones of the deck contrast with the cool blue water. Beyond, a pathway leads to a wooden dock extending over the bay, with the serene water and palm trees in the background.
Home in Bastimentos Island
4.83 out of 5 average rating, 132 reviews

Spacious, Over the Water Home with Plunge Pool

Perched over the water in Bastimentos Bay, this well-appointed four bedroom and three bath single family home combines classic Caribbean architecture with modern sensabilities. With over 2,000 sq ft of comfortably furnished spaces, there’s room enough for eight adults to spend time together - or apart - in any weather. BBQ poolside, stargaze from the hammocks, fish off the dock, walk to restaurants, or flag down a water taxi from your private boat dock for the ten minute trip to Bocastown.

Top guest favourite
Flat in Maria Chiquita
4.95 out of 5 average rating, 132 reviews

Spacious 4Br Beachside Getaway at Playa Escondida

Escape to Playa Escondida Resort & Marina for the ultimate luxury getaway. Our 4Br beachfront apartment is ideal for families and friends seeking relaxation in the Caribbean Sea. Indulge in plush rooms, white sand beaches, and unforgettable sunsets. Our fully equipped apartment provides everything you need for an exceptional stay, and our unparalleled service ensures you'll never want to leave. Best of all, it's just an hour away from Panama City. Book now for a truly unforgettable experience.

Guest favourite
Villa in Farallon
4.9 out of 5 average rating, 238 reviews

Costa Blanca Beach & Golf Villa by Decameron

Spacious Villa with Pool, Golf Views & Beach Access Relax in this stylish 4-bedroom villa overlooking the 7th putting green of Mantarraya Golf Course. All on one level, it offers 250 sq m of comfort, with en-suite bathrooms and space for up to 12 guests. Wow ! - Private 15 m pool with shallow area - 15-minute walk to Pacific beach - Access to Owners Beach Club (restaurant + parking) - Peaceful golf course setting Perfect for families, groups, or golf lovers seeking sun and serenity.

Top guest favourite
A large saltwater pool reflects the blue sky and surrounding palm trees, creating a serene atmosphere. Adjacent seating and shaded areas are visible, offering spaces for relaxation. Lush landscaping surrounds the pool deck, enhancing the overall tranquil environment.
Home in Rio Hato
4.98 out of 5 average rating, 132 reviews

Private House | Beach | Quiet Stays | Wi-Fi | A/C

Discover the pleasure of staying in a private, elegant, and light-filled villa within the exclusive Playa Blanca Beach & Lagoon. Start your day with the tropical breeze on the terrace, relax by the pool, and enjoy a short 10-minute walk to the beach. Perfect for families and travelers seeking rest, security, and resort-style comfort. Ideally located 10 minutes from Scarlett Martínez Airport and 2 hours from Panama City, it's the perfect place for an unforgettable getaway by the sea.

Top guest favourite
Home in San Carlos
4.94 out of 5 average rating, 144 reviews

OceanView-Rooftop Jacuzzi&Pool | Concierge Service

Unique 3-story beach house – one of a kind. 7 bedrooms, 13 beds, 8.5 baths. hot water. Every room with full bath -AC’s and ceiling fans in all rooms, separate laundry -Rooftop area pool, Jacuzzi, bar, BBQ(charcoal & gas) with amazing ocean view -High ceilings, large open kitchen and living area. -Spacious balcony for dining or relaxing. - 5 min. walk to the beach. -Parking for up to 7 cars - Base rate covers up to 4 guests, with a $40 charge per additional person, per night.

Top guest favourite
The image shows a bright outdoor area featuring a clear blue swimming pool bordered by light stone paths and lush green grass. A tall palm tree provides shade in the foreground, while the backyard includes a single-story house and an open patio area under a roof.
Villa in Punta Chame
4.97 out of 5 average rating, 138 reviews

Beach House with Pool/Gazebo in Punta Chame!

"Disconnect from the routine and enjoy a sunny environment. Just breathe fresh air in a different surroundings. Enjoy a few days in the pool, relaxed in a hammock and of course steps from a spectacular beach with views of the city and islands. The house has 4 bedrooms, 3.5 bathrooms, electric plant and all the facilities to enjoy and rest. Close to restaurants and the best beach to do and see kitesurfing adventures, fish, SUP, etc. Only 90 minutes from the city"

Guest favourite
The modern house is set against a backdrop of rolling mountains, illuminated by the soft glow of evening light. A spacious entrance is visible, with large sliding doors opening to inviting communal areas. Lush greenery surrounds the property, enhancing its natural appeal.
Villa in El Copé
4.92 out of 5 average rating, 186 reviews

Mountain retreat

Our beautiful, modern, comfortable house is designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and also a base to explore the area which is in a beautiful part of Panama near a cloud forest national park with amazing hiking to waterfalls and local communities. The house is large, sleeping 12, within 17 acres of forest with rivers for swimming. We can arrange tours and hosted retreats for yoga, cooking and more.

Top guest favourite
A private pool area is framed by lush tropical plants and trees, with lounge chairs situated nearby. The pool’s clear blue water reflects the surrounding greenery and the structure in the background, which includes a covered patio for relaxation.
Home in Las Colinas de Caceres de Arraijan
4.98 out of 5 average rating, 222 reviews

Tropical Haven with Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Top guest favourite
Apartment in Maria Chiquita
5 out of 5 average rating, 9 reviews

escondidapanama | 504A | Golf Cart | 11 | 4BR/4BA

escondidapanama • Penthouse 504A in Playa Escondida designed for luxury stays • Ideal for families and groups • 5-meter-high living room with a 100” TV • Custom kitchen for cooking and entertaining • Large patio with dining area and marina + ocean views • Sleeps 9 in bedrooms + 2 on living room sofas • Master suite with 100” TV and glass-ceiling double shower • Golf cart included for easy access to the resort and Marina

Top guest favourite
An expansive villa is showcased with large glass windows and a spacious outdoor area. A clear swimming pool is visible in the foreground, alongside a separate jacuzzi. Multiple lounge chairs are arranged near the pool, and lush greenery surrounds the property.
Villa in Costa Esmeralda
4.97 out of 5 average rating, 116 reviews

#1 Villa with a swimming pool, jacuzzi, pool table, and ping pong.

Spectacular villa a few minutes from the beach by car, super spacious, ideal to share with family, friends or corporate meetings. The property is full of surprises and with many things to do including its swimming pool, jacuzzi, pool table, ping pong table, domino table, hammocks, large green areas, gas BBQ, variety of board games and a fully equipped kitchen.

Top guest favourite
A vibrant garden features lush green foliage, including palm trees and large agave plants. The view reveals the sandy beach and ocean beyond, with gentle waves lapping at the shore under a clear sky, creating a serene atmosphere.
Home in Nueva Gorgona
5 out of 5 average rating, 25 reviews

Spectacular Beachfront House

Beautiful house with private beach access right on the property. Relax on the hammocks and be surrounded by nature, with the best ocean view. Only 10 minutes drive from Coronado with all its amenities. There are two wonderful caretakers on the property who are in charge of security, cleaning, and can answer questions and help you with anything you need.

Guest favourite
A serene beachfront setting features palm trees swaying gently by the water's edge. Loungers are arranged along the sandy shore, providing ample space for relaxation. A calm pool glistens nearby, seamlessly merging with the turquoise sea under a clear blue sky.
Apartment in Buenaventura, El Chirú
4.9 out of 5 average rating, 149 reviews

Modern | Steps to Beach Club & Shops | Sleeps 10

• Beautiful design • Excellent location • Steps to the La Mansa Beach Club! • Spacious & luxurious • Luxury Bedding • 75 inches TV • Beautiful views! • Half a block from restaurants & convenience store! • Fully equipped • High speed internet • Buenaventura, best luxury beach resort in Panama

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