
Holiday rentals in Panama
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Panama
Guests agree: these stays are highly rated for location, cleanliness and more.

Puntita Manzanillo, fantastic sea and jungle
Come visit one of the most unique and exclusive properties in the Panamanian Caribbean. A magical completely private 5 acre property nestled between the Caribbean Sea (500meters of ocean front) and the jungle. Surrounded by a garden of corals and visited by monkeys and macaws. Our energy is solar and we have our own aqueduct. Temperature oscillates between 72 and 84 degrees F. It is rented in its entirety. It has 3 one bedroom cabins with full baths. Satellite Internet (Starlink) is provided.

Bocas Sunset Beach House
Beautiful Eco Beach House with luxury touches! Relax on your spacious private deck overlooking the coral reef. Snorkel right off the dock or hop into the warm water from your beachfront cabana. Be mesmerized by the vivid overwater sunsets in front, coconut grove on either side, and lush rainforest behind. Fall asleep to the tranquil sound of waves lapping below. Wake refreshed with coconut water from your own coconut grove. Our team looks forward to welcoming you! -GoGo, Mili, Mikel, Eimy, Baby

Beach House-Amazing Pool & Jacuzzi - Pet Friendly
Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Cozy open space, unique jungle views, river access
An open-style jungle home with mesmerizing treetop and mountain views. Located 10 minute walk to the beach, with a trail that leads to the River. The house is not childproof! It has three individual bedrooms, each with its own key. The price is based on the number of guests. The entire house is always yours. The house offers fiber optic WiFi and two dedicated workspaces. The property is surrounded by large trees, naturally keep the house cool and provide shelter for birds and wildlife.

Boquete Bees and Butterflies Casitas
Romantic setting, immersed in nature and yet close to town. Fibre Optic Internet. Nestled in extensive tropical gardens on a traditional Boquete Coffee Estate. Abundance of birds, feeders and native bee hives. We are home to Panamas largest butterfly exhibit and specialty honey company. We offer a hearty breakfast. We can accommodate 4 px but booking price including breakfast is for 2px. We charge an additional $15 per person over 12 yrs, an additional $10 for children under 12 yrs

Patty’s Casco 2BR Loft | Balcony & Personal Touch
“Feel at home in Casco Viejo—personally welcomed by your hosts, Patty & Rudy.” Stay in the Heart of Casco Viejo with Patty’s Casitas! Prime Casco Viejo Location | Quiet, Convenient & Charming Stay steps from restaurants, cafés, bars, and plazas—right by the El Rey boutique supermarket and the waterfront promenade. This peaceful spot is rare in Casco, tucked away from rooftop noise and perfectly located at the entrance of the neighborhood for easy in & out access!

Casa Rosie - Dream Home on Tabogá Island
Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Luxury Balcony Stays + Pool Casco Viejo
Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.

The apartment of a legendary Panamanian footballer
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Cocovivo Mangrove Treehouse
This secluded loft-style treehouse sits on stilts above the water, 30 feet from our colorful coral reef. Transparent and airy but bug proof walls let you enjoy the fresh ocean breeze and views while keeping you safe and cozy. When a sloth comes to visit, no need to leave the house to see him! Blend in with the surroundings of mangrove, lagoon and jungle, and enjoy water and reef access from your own deck. Bright and airy, 100% eco-conscious.

Casa De Ola, Jungle Beach Cabin
Welcome to Paradise: Your Pacific Jungle Oasis Nestled deep within the lush, untamed heart of Panama's wild Pacific coast, this remote jungle cabin isn't just a place to stay—it's an invitation to experience life at its most primal and extraordinary. It is a destination by itself. This is your passport to a world where nature reigns supreme, adventure lurks around every emerald-green corner, and artistry dances with the elements.

Coffee Cabins - Cabin 2
Welcome to the Coffee Cabins. This is one of four stunning A-frame cabins perched on the side of a mountain in the middle of a coffee field. You’re literally surrounded by coffee, both on the trees and in your kitchen with the complimentary coffee grown right here on the farm. Enjoy larger than life views to both the north towards the continental divide and to the west framing Volcan Baru, Panama’s highest peak.
Popular amenities for Panama holiday rentals
Other great holiday rentals in Panama

La Casa de la Cascada

Luxury Centric 2BR Apartment in Casco Viejo

Fobos – Luxury 1-Bed Cabin with Heated Pool

Private parking & rooftop | Studio Casco Center

Off-Grid Bluff Beach Home for Families or Couples

On the Beach Villa in Boca Chica!

Luxury apt in Panama City 2 Rooms 3 Baths

Gorgeous Flat in the best location in Casco Viejo
Destinations to explore
- Beach apartment rentals Panama
- Flat rentals Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- House rentals Panama
- Pet-friendly rentals Panama
- Rentals with a patio Panama
- Nature eco lodge rentals Panama
- Rentals with lake access Panama
- Family-friendly rentals Panama
- Dome rentals Panama
- Rentals with an accessible-height bed Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Bed and breakfasts Panama
- Holiday home rentals Panama
- Smoking-friendly rentals Panama
- Earth house rentals Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Bungalow rentals Panama
- Rentals with breakfast Panama
- Rentals with a firepit Panama
- Aparthotel rentals Panama
- Hotel rooms Panama
- Fitness-friendly rentals Panama
- Tent rentals Panama
- Beach house rentals Panama
- Villa rentals Panama
- Tiny house rentals Panama
- Chalet rentals Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Rentals with a cinema Panama
- Cottage rentals Panama
- Rentals with beach access Panama
- Loft rentals Panama
- Boat rentals Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Farm stay rentals Panama
- Lakehouse rentals Panama
- Rentals with a hot tub Panama
- Guest house rentals Panama
- Rentals with a washing machine and dryer Panama
- Boutique hotels Panama
- Rentals with pools Panama
- Apartment rentals Panama
- Rentals with a fireplace Panama
- Container rentals Panama
- Townhouse rentals Panama
- Treehouse rentals Panama
- Waterfront rentals Panama
- Rentals with a sauna Panama
- Island rentals Panama




