Guest house holiday rentals in Pima County

Find and book unique guest house rentals on Airbnb

Top-rated guest house rentals in Pima County

Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

%{current} / %{total}1 / 1
Top guest favourite
A vibrant, sunlit patio area showcases colorful wall art on bright orange walls. A small table with two chairs sits beneath lush greenery, providing a perfect spot for outdoor dining. The space is adorned with various plants, enhancing the inviting atmosphere.
Guest house in Tucson
4.95 out of 5 average rating, 433 reviews

Oasis: Casita Colibrí - Little Hummingbird House

Casita Colibrí - a lush desert oasis flourishing with life in the heart of Tucson. Tucked among fruit trees & gardens, this micro urban farm is home to a koi pond, chickens, giant tortoise, dogs, cats, and its namesake, hummingbirds. Enjoy fresh eggs, wander garden paths, relax poolside, or watch koi glide beneath the waterfall. It's just a place to stay—it’s a special place to slow down, reconnect, and breathe in beauty of the Sonoran Desert, where peace and magic are woven into every corner.

Top guest favourite
A bright main room features a spacious bed dressed in a vibrant yellow and white blanket. Comfortable seating options, including a pair of light-toned sofas, are arranged around a wooden table. Natural light filters through partially covered windows, enhancing the welcoming atmosphere.
Guest house in Tucson
4.99 out of 5 average rating, 296 reviews

RetroTrek Bungalow Private-Fenced-Cozy

Our bungalow is nicely suited for 2, features a separate kitchen, a 3/4 bath, & large main room for sleeping or relaxing. We offer a private entrance with carport parking. Yard is fenced, with dog door, up to 2pets are welcome. Centrally located, within minutes of the airport, downtown and the University of Arizona. We are within walking distance to Reid Park for golfing or a visit to the Zoo. Even though we are midtown with easy access to many areas of town, you will find it surprisingly quiet.

Top guest favourite
Guest house in Tucson
4.97 out of 5 average rating, 436 reviews

The Zendo Oasis. Your Private Resort in Tucson.

Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in an infrared or hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies—lounge in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Top guest favourite
Guest house in Tucson
4.94 out of 5 average rating, 192 reviews

Private Casita in Casas Adobes

Family friendly (with ungated pool) 411sq ft Private Casita newly REMODELED! Sleeps up to 4. King feather bed & a pullout queen sleeper. Located just past a quaint garden where you can catch hummingbirds drinking. Private parking & entrance, just come and go. ASK ABOUT: Our other King Suite just feet away! Can sleep additional 2 guests! Cool off in pool, use outside patio (where cooking station is located, there's no kitchen in the casita). Min. from I-10 & stellar Tucson Biking Loop!!

Top guest favourite
A cozy living area features a light-colored sofa and two blue accent chairs. A round coffee table sits in the center, with a wooden TV stand showcasing a vibrant piece of art. Large windows provide natural light and overlook the landscaped outdoor space.
Guest house in Tucson
4.99 out of 5 average rating, 157 reviews

Peaceful Desert Oasis in Central Tucson Foothills

Newly renovated guest home located in a quiet central area in the Catalina Foothills. Trails and biking in our backyard, 10-15 min drive to hiking/parks, downtown and UofA! Away from everything and yet conveniently close to everything! Enjoy beautiful mountain views and professional landscaping. Well equipped kitchen with washer/dryer and a cozy fireplace and desk in the master bedroom. Lots of privacy from the main home. Stocked with all your amenities needed for a cozy and comfortable stay.

Top guest favourite
The guesthouse is set against a backdrop of desert landscape, showcasing a simple, earthy exterior. A wooden porch with railings invites guests to enjoy the outdoor space. Desert vegetation, including cacti and shrubs, enhances the natural surroundings, along with rocky pathways leading to the house.
Guest house in Tucson
4.99 out of 5 average rating, 354 reviews

West-side Trailhead Retreat in the Sonoran Desert

2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.

Top guest favourite
A cozy living area is displayed with a brown sofa adorned with colorful throw pillows. A wooden coffee table sits in the center, surrounded by a woven decorative basket. Natural light filters through the large window framed by blue curtains, illuminating the warm hues of the walls.
Guest house in Tucson
4.98 out of 5 average rating, 348 reviews

Tranquil Bears Path Casita

This Property is truly a unique oasis in the desert! It is one of the few urban areas in Tucson that offers you the best of both worlds! A place to come home to and enjoy the quiet nights, plentiful stars, and walks among the the numerous Saguaros, Mesquite and Desert Pine trees. All while being right in the heart of Tucson's East side just minutes from shopping and restaurants! Our extraordinary place is close to Mt Lemon, Sabino Canyon, hiking, running, biking trails and riding stables.

Top guest favourite
A scenic view of the Santa Catalina Mountains under a partly cloudy sky is presented. The landscape is characterized by rolling hills and desert vegetation, with a dirt road leading into the distance. The tranquil atmosphere is enhanced by the natural surroundings.
Guest house in Tucson
4.99 out of 5 average rating, 225 reviews

Cozy Mountain Retreat w/ Hot Tub

Come visit our small horse ranch in NW Tucson! Tucked into the foothills of the Santa Catalina Mountains, you’ll enjoy great views, and slightly cooler temperatures. You'll be close enough to town to have access restaurants,shopping, entertainment, etc, yet you'll have unlimited access to hiking and mountain biking right out our gate. * Not suitable for children under 12yrs. **This is a smoke-free property, sorry, no exceptions. *you must be able to climb a small flight of stairs*

Top guest favourite
A comfortable living area is presented, featuring a brown leather sofa opposite a circular wooden coffee table. A colorful area rug adds texture to the floor, while a floor lamp and a large mirror enhance the inviting ambiance. Bright yellow curtains frame a nearby window.
Guest house in Tucson
4.98 out of 5 average rating, 486 reviews

The Southwest Knest

Cozy and charming, this private guest house sits in the heart of Tucson and makes a perfect home base during your visit to the Southwest! Studio layout is spacious and relaxing for 2. Fully equipped kitchen, bathroom with walk-in shower, Ghostbed mattress, and comfortable work space/fast wifi for those of you working remotely. Easy access to airport, U of A, Saguaro NP, shopping, and hiking trails. Coded entry makes it a breeze to come and go, no shared keys. Come rest at the Knest!

Guest favourite
A spacious outdoor area features a rustic wooden table surrounded by minimalistic white seating. A large striped umbrella adds a touch of shade, and string lights hang overhead. The white-walled courtyard is adorned with a variety of desert plants and accents, contributing to a tranquil atmosphere.
Guest house in Tucson
4.88 out of 5 average rating, 112 reviews

Adobe House in Saguaro Nat. Park on 1 acre

✷ Scenic Location ✷ Fastest WiFi ✷ Huge Outdoor Fully Fence Living Space ✷ Low cleaning fees ✷ Pet Friendly ✷ For more pictures and videos, find us on social media! Follow @casajaguartucson We believe that true peace is found through a connection to nature, in a home where every detail has been carefully considered. Welcome to Casa Jaguar, the ideal desert getaway located in Saguaro National Park for those seeking to reconnect with nature and revitalize their spirit.

Top guest favourite
A spacious studio features a queen-sized bed adorned with a soft coverlet. A curved red lounge chair complements the warm adobe walls and wooden ceiling beams. Natural light filters through large windows, illuminating the cozy corner with a beehive fireplace, enhancing the tranquil atmosphere.
Guest house in Tucson
4.96 out of 5 average rating, 884 reviews

Tucson Poet's Studio

Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Top guest favourite
Guest house in Tucson
5 out of 5 average rating, 295 reviews

Saguaro Courtyard Retreat near National Park

If you love nature this casita is just for you. Located 15 minutes from downtown and only a few minutes from stunning hiking and mountain biking trails in the National Park. The property is very much like a botanical garden with fruit trees filling up the back and a wide variety of succulents filling the front. The casita has its own private porch while the property shares two large communal patios with outdoor dining and a fire pit.

Popular amenities for guest house rentals in Pima County

Destinations to explore