
Guest house holiday rentals in Pima County
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in Pima County
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

The Zendo Oasis. Your Private Resort in Tucson.
Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in an infrared or hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies—lounge in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Peaceful Desert Oasis in Central Tucson Foothills
Newly renovated guest home located in a quiet central area in the Catalina Foothills. Trails and biking in our backyard, 10-15 min drive to hiking/parks, downtown and UofA! Away from everything and yet conveniently close to everything! Enjoy beautiful mountain views and professional landscaping. Well equipped kitchen with washer/dryer and a cozy fireplace and desk in the master bedroom. Lots of privacy from the main home. Stocked with all your amenities needed for a cozy and comfortable stay.

Studio in the Saguaro Forest
New modern studio guesthouse on 3.2 lush acres secluded at the edge of the Saguaro National Park! Cleaning fees included in nightly rate. Private indoor/outdoor living areas. 8 miles easy access to downtown, 9 miles to the Desert Museum. High speed Starlink WiFi, Tuft & Needle queen bed, washer/dryer combo, 4k smart TV, whisper quiet mini split, full size sleeper sofa for 3rd guest. Nice retreat from midtown traffic. Check out my other similar listing on the property. LICENSE: 21465687

Newly Constructed Downtown Guesthouse
This newly constructed, spacious guest house has an open floor plan with a loft bedroom featuring the most cozy queen-sized bed. The bathroom has a soaking tub and there’s an outdoor shower too. There’s a large gated yard and three porches on which to enjoy a morning cup of coffee or tea. Located in the coveted Dunbar Spring neighborhood, the home is walking distance to the University of Arizona, 4th Ave, downtown, lots of coffee shops and restaurants and the Warehouse Arts District.

The Southwest Knest
Cozy and charming, this private guest house sits in the heart of Tucson and makes a perfect home base during your visit to the Southwest! Studio layout is spacious and relaxing for 2. Fully equipped kitchen, bathroom with walk-in shower, Ghostbed mattress, and comfortable work space/fast wifi for those of you working remotely. Easy access to airport, U of A, Saguaro NP, shopping, and hiking trails. Coded entry makes it a breeze to come and go, no shared keys. Come rest at the Knest!

Attractive Casita In Tucson
A charming getaway casita with stunning views of the majestic Saguaro National Park and the Picture Rock Mountains for spectacular sunsets. The 5-acre site is home to many varieties of cacti, including giant saguaros and other native plants and trees. Through the casita's panoramic windows, you can observe desert vegetation, birds, rabbits, coyotes, bobcats, javelinas, and deer. An evening bath in the jacuzzi under the starry sky will certainly remain in your memory for a long time.

The Coop- Luxury guest house with ideal location
This luxury guest home was originally a chicken coop for a farmer over 60 years who owned the majority of the land in the area. With an addition and a complete renovation, we have designed this for the perfect vacation rental ideally located in Tucson. 15 minutes to Banner and the U of A. 10 minutes to Oro Valley or the freeway. The stylish guest home is separated from our home and designed with privacy in mind. Enjoy this brand new house for your stay with experienced hosts.

Tucson Poet's Studio
Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Central Casita Minutes from UA & Downtown
Perfect for a weekend getaway or a long-term stay, our casita in midtown is fully equipped with everything you need to experience all that Tucson has to offer. 344 sq ft, this small and mighty space offers a fully-equipped kitchenette, theater-quality entertainment center, high speed wifi access, and washer and dryer access. Enjoy the spacious patio while you sip morning coffee or grill in the evening. You may find it hard to check-out of this cozy gem!

Saguaro Oasis Retreat near National Park
If you love nature this casita is just for you. Located 15 minutes from downtown and only a few minutes from stunning hiking and mountain biking trails in the National Park. The property is very much like a botanical garden with fruit trees filling up the back and a wide variety of succulents filling the front. The casita has its own private porch while the property shares two large communal patios with outdoor dining and a fire pit.

Tiny House in Central Tucson
A great location in central Tucson in an artists sculpture garden. Private and quiet, in a friendly Enclave. Bathroom is shared, and 2 outdoor kitchens are shared. Patio dining areas available, completely furnished, Wifi, microwave, fridge, appliances, and close to coffee shop, restaurants, three major hospitals, and the University. Sorry, but it's not available for couples. Please introduce yourself - thanks much!

Spanish Bungalow Casita with Private Patio
This one of a kind Spanish Bungalow is among the finest accommodations in Tucson. Nestled in the heart of Tucson, distinguished by modern amenities and historic character. The Spanish Bungalow is located walking distance from Downtown, the best Mexican restaurants in the city and minutes away from the U of A, and so much more. Come relax and enjoy the thoughtful privacy this bungalow has to offer.
Popular amenities for guest house rentals in Pima County
Family-friendly guest house rentals

Charming Private Oasis Casita with Pool & Hot Tub

Cozy hideaway cottage in historic Ajo

Oasis: Casita Colibrí - Little Hummingbird House

Cozy Rio Rico guesthouse with a view

Peaceful 4-Acre Desert Casita with Shared Hot Tub

Long term perfect: fenced, work desk, fast Wi-Fi

Cozy Desert Foothills Getaway

Charming Private Guesthouse with Mountain View
Guest house rentals with a patio

Coyote Cavern: A Southwestern High Desert Retreat

*Prime Location: King Suite Guest House!*

Cute eco-built guesthouse

Tranquil Modern Guest House

Midtown House near TMC & UofA•Fast WiFi •Self ChIn

Historic University area Downtown 4th Ave Studio!

Sunshine Loft

Casita Chapulin
Guest house rentals with a washing machine and dryer

The Outpost

Solar Powered Guest House Near UA—No Cleaning Fee!

The Casita

Eco-Chic Studio Casita | Near UA, 4th & Dog Park

Blue Lake Boutique Hotel

Golden moments in Oro Valley/Tucson

Mi Casita in Historic Downtown

Serene Desert Casita No cleaning fee, Pets welcome
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- University of Arizona
- Arizona-Sonora Desert Museum
- Tucson Botanical Gardens
- University of Arizona
- Reid Park Zoo
- Tumamoc Hill
- Titan Missile Museum
- Mission San Xavier del Bac
- Kino Sports Complex
- Tucson Convention Center
- Children's Museum Tucson
- Rialto Theatre
- Tucson Museum of Art
- Mini Time Machine Museum of Miniatures
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