
Holiday rentals in Panama
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Panama
Guests agree: these stays are highly rated for location, cleanliness and more.

Puntita Manzanillo, fantastic sea and jungle
Come visit one of the most unique and exclusive properties in the Panamanian Caribbean. A magical completely private 5 acre property nestled between the Caribbean Sea (500meters of ocean front) and the jungle. Surrounded by a garden of corals and visited by monkeys and macaws. Our energy is solar and we have our own aqueduct. Temperature oscillates between 72 and 84 degrees F. It is rented in its entirety. It has 3 one bedroom cabins with full baths. Satellite Internet (Starlink) is provided.

Bocas Sunset Beach House
Beautiful Eco Beach House with luxury touches! Relax on your spacious private deck overlooking the coral reef. Snorkel right off the dock or hop into the warm water from your beachfront cabana. Be mesmerized by the vivid overwater sunsets in front, coconut grove on either side, and lush rainforest behind. Fall asleep to the tranquil sound of waves lapping below. Wake refreshed with coconut water from your own coconut grove. Our team looks forward to welcoming you! -GoGo, Mili, Mikel, Eimy, Baby

Beachfront Gem w/ Ocean Views & Prime Surf Access
Welcome to your slice of beachfront paradise! Our home sits right on Cambutal's beautiful shoreline. Gorgeous ocean views greet you from every window, while the gentle rhythm of waves creates the perfect soundtrack for your stay. We've equipped the house with Starlink WiFi and a large dining table that doubles as an ideal workspace, making this a perfect retreat for both vacationers and remote workers. The house feels like a real home – comfortable, clean, and ready for your beach memories.

Cozy open space, unique jungle views, river access
An open-style jungle home with mesmerizing treetop and mountain views. Located 10 minute walk to the beach, with a trail that leads to the River. The house is not childproof! It has three individual bedrooms, each with its own key. The price is based on the number of guests. The entire house is always yours. The house offers fiber optic WiFi and two dedicated workspaces. The property is surrounded by large trees, naturally keep the house cool and provide shelter for birds and wildlife.

FACING THE SEA Cacique (Portobello Park)
A house! A real glass island in the heart of the jungle! In the middle of the Portobello National Park (access only by 4x4 AWD) nestled at the top of the hill, between sky/sea, away from all eyes, a transparent house where glass embraces nature on all sides creating a unique connection between the inside and the outside, ideal for resting, disconnecting, comfortable, spacious, cool (central air conditioning), exclusive. It is the witness of a grandiose spectacle that awaits you!

Luxury Balcony Stays + Pool Casco Viejo
Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.

The apartment of a legendary Panamanian footballer
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Casa Samambaia - sea view tropical paradise w pool
With a modern tropical design, this home features a cozy living room and a stylish kitchen at the center of the social area. Open the glass doors to immerse yourself in open-concept living, seamlessly blending the indoors with the main terrace and the pool, all oriented towards the ocean view. With two en-suite bedrooms with AC and fans, the house is immersed in nature, green mountains, and a lovely garden, everything 5 minutes from the beach center.

Amazing loft with an iconic view of Casco Viejo
Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Casa Pelicano - Tropical house w pool and seaview
Welcome to Casa Pelicano! Indulge yourself in a retreat with breathtaking views of the ocean and mountains from every corner. Unwind in the private refreshing pool, where the turquoise waters seem to blend seamlessly with the horizon. The stylish interior features open-plan living spaces, perfect for entertaining or relaxing. Whether you're soaking up the sun or gazing at the moonlit ocean under the stars, this home is your ultimate escape.

Cocovivo Mangrove Tree house
This secluded loft-style treehouse sits on stilts above the water, 30 feet from our colorful coral reef. Transparent and airy but bug proof walls let you enjoy the fresh ocean breeze and views while keeping you safe and cozy. When a sloth comes to visit, no need to leave the house to see him! Blend in with the surroundings of mangrove, lagoon and jungle, and enjoy water and reef access from your own deck. Bright and airy, 100% eco-conscious.

Casa De Ola, Jungle Beach Cabin
Welcome to Paradise: Your Pacific Jungle Oasis Nestled deep within the lush, untamed heart of Panama's wild Pacific coast, this remote jungle cabin isn't just a place to stay—it's an invitation to experience life at its most primal and extraordinary. It is a destination by itself. This is your passport to a world where nature reigns supreme, adventure lurks around every emerald-green corner, and artistry dances with the elements.
Popular amenities for Panama holiday rentals
Other great holiday rentals in Panama

Luxury Centric 2BR Apartment in Casco Viejo

Bocas Overwater Luxury Villa & Lodge

Off-Grid Bluff Beach Home for Families or Couples

On the Beach Villa in Boca Chica!

Blue Sky Lodge; the best view in Altos del María

Casco Viejo Dream Loft – Cozy & Central 1BR Apt

Carenero Hills 3 - Beach & Surf Bungalows.

Tropicool Loft w/rooftop steps from Casco
Destinations to explore
- Beach apartment rentals Panama
- Dome rentals Panama
- Rentals with pools Panama
- Treehouse rentals Panama
- Lakehouse rentals Panama
- Rentals with a hot tub Panama
- Villa rentals Panama
- Tiny house rentals Panama
- Cottage rentals Panama
- Rentals with a fireplace Panama
- Container rentals Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Island rentals Panama
- Townhouse rentals Panama
- Nature eco lodge rentals Panama
- Rentals with a cinema Panama
- Apartment rentals Panama
- Rentals with a sauna Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Aparthotel rentals Panama
- Hotel rooms Panama
- Beach house rentals Panama
- Smoking-friendly rentals Panama
- Rentals with beach access Panama
- House rentals Panama
- Rentals with breakfast Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Rentals with lake access Panama
- Rentals with a patio Panama
- Rentals with a firepit Panama
- Family-friendly rentals Panama
- Chalet rentals Panama
- Tent rentals Panama
- Fitness-friendly rentals Panama
- Boutique hotels Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Farm stay rentals Panama
- Holiday home rentals Panama
- Waterfront rentals Panama
- Bed and breakfasts Panama
- Guest house rentals Panama
- Rentals with a washing machine and dryer Panama
- Earth house rentals Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Pet-friendly rentals Panama
- Bungalow rentals Panama
- Flat rentals Panama
- Boat rentals Panama
- Loft rentals Panama
- Rentals with an accessible-height bed Panama




