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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
Loft in Ayapango de Gabriel Ramos M.
5 out of 5 average rating, 17 reviews

Hermoso departamento con Jardín y vista al Volcán

Escápate a un refugio de ensueño en la ruta de los volcanes. Perfecto para escapadas románticas o reuniones familiares. Disfruta de Vista impresionante a los volcanes desde tu jardín privado, área de asadores y horno de piedra saca el chef que llevas dentro. Espacio amplio y acogedor para relajarte y disfrutar. Ubicado en un pintoresco poblado cerca del parque nacional Iztapopo, este oasis es el lugar ideal para desconectar y reconectar con la naturaleza y tus seres queridos.

Top guest favourite
Flat in Roma Norte
5 out of 5 average rating, 14 reviews

Roma Norte · Architect-Designed 2BR Apartment

A duplex residence conceived by a recognized architecture studio and furnished by one of Mexico City’s leading design firms. Every material, finish, and object was selected with intention — nothing is accidental. Steps from Roma Norte’s best restaurants, cafés, and galleries. Everything you need is walkable; everything inside is intentional. Full kitchen, premium linens, fast Wi-Fi, and a host committed to one standard: every guest leaves wishing they’d stayed longer.

Superhost
A cozy bedroom features a spacious bed with a soft grey headboard and decorative cushions. A sleek bedside lamp provides gentle illumination, while modern wooden cabinetry adds warmth to the space. A grey armchair is positioned nearby, complemented by delicate white flowers in the foreground.
Loft in Tlalpan
4.87 out of 5 average rating, 916 reviews

Punto Lofts Periférico Sur

Punto Lofts Periférico Sur es un concepto moderno con 18 lofts totalmente equipados, ideales para estancias cortas o largas. Cada loft aloja hasta 3 personas y cuenta con cama Queen Size y sofá cama, ofreciendo comodidad y descanso. Disfruta de recepción 24/7, acceso con llave digital y altos estándares de limpieza y seguridad. Ubicado sobre Periférico Sur, frente al Estadio Azteca, con fácil acceso a hospitales, restaurantes y centros comerciales.

Guest favourite
A spacious living area features a high ceiling and exposed brick walls, illuminated by soft lighting. A large mirror hangs above a simple coffee table, surrounded by a cozy sofa and two armchairs. Indoor plants add a touch of nature to the inviting space.
Casa particular in Álvaro Obregón
4.94 out of 5 average rating, 31 reviews

Mi Refugio San Angel

Mi Refugio San Angel, is a spacious and modern space, to feel out of the city, being centrally in it. It has a Temazcal (under reservation), hydromassage tub, terraces, garden with hammocks, lounge chair, outdoor dining area, bonfire area, indoor fireplace. 2 rooms with full bathroom, queen size sofa bed; open, spacious and fully equipped kitchen. Private parking. The main room can be opened to a view towards the double height of its large room.

Top guest favourite
Flat in Amecameca
4.98 out of 5 average rating, 47 reviews

Wulkan Studio+Desayuno Incluido

Exclusive studio in the heart of Amecameca de Juárez, just 15 meters from the bus terminal (Volcanes). It features a fully equipped bathroom, a spacious room, a TV and work area, an independent entrance, self check-in, and automated lighting. Enjoy its unique colonial-style façade and a delicious included breakfast. Perfect for relaxing or working comfortably. The only studio with these features in the city!

Top guest favourite
Cabin in Tlalmanalco de Velázquez
5 out of 5 average rating, 11 reviews

Casita cerca a los volcanes.

Casita de pueblo cerca de los volcanes Disfruta una escapada única en nuestra acogedora casita, ideal para 2 a 4 personas. Perfecta para familias que desean pasar un fin de semana tranquilo y acogedor. Incluye: Cama (King Size) + sofá cama (King Size) Cocinita Frigobar Horno de microondas Tv Wifi Accesorios de cocina Vive la experiencia local con comodidad y encanto, muy cerca de los volcan.

Superhost
Flat in Tláhuac
4.83 out of 5 average rating, 54 reviews

A Departamento remodelado, cocina y jardín.

A 10 Cuadras del Metro Linea 12 Terminal Tlahuac, Departamento Independiente con servicio de cocina, baño completo, pequeña sala de descanso, antecomedor con Refrigerador, microondas y cama matrimonial y un lugar de estacionamiento. Se puede hacer uso de un bonito asador de leña y carbón mas parrilla de gas en el amplio jardín, o simplemente pasar la tarde en el patio rodeado de vegetacion.

Guest favourite
A spacious sleeping area features a large bed with neutral bedding, flanked by two wooden nightstands. A colorful woven rug adds texture to the floor. A full-length mirror is positioned against the wall, reflecting the room's minimalist design, enhanced by natural light.
Home in Roma Norte
4.89 out of 5 average rating, 157 reviews

Nueva Casa Rosa en el corazón de la colonia Roma

Una hermosa y - recién remodelada - casa rosada en el corazón de la colonia Roma. Un hogar fuera de casa para pasar unos días o una temporada larga cerca de sitios históricos, tiendas y restaurantes locales en un barrio con actitud. Todas las comodidades en una casa con personalidad y una arquitectura e interiorismo impecables.

Top guest favourite
A charming outdoor patio is surrounded by vibrant greenery and a blue-walled house. A round glass table is complemented by six white metal chairs, creating an inviting space for dining or gathering. Potted plants and flowers add color to the serene environment.
Home in Coyoacán
4.97 out of 5 average rating, 106 reviews

Casa Omac | Colonial house with two patios

Typical colonial house, located in the most picturesque and emblematic street of Coyoacán. The style is reminiscent of Frida Kahlo's Blue House, which is a few minutes' walk away. Organized around a large internal patio, the house has 5 double rooms and can host up to 10 people, making it ideal for groups and families.

Top guest favourite
A charming mini cabin is displayed, featuring a brick exterior and a welcoming porch. Two red Adirondack chairs are positioned on the manicured lawn, surrounded by greenery. The clear blue sky and sunlight enhance the tranquil setting of this inviting retreat.
Cabin in 012
4.95 out of 5 average rating, 125 reviews

The Marcela & David – Cozy Tiny Cabin Experience

Welcome to The Marcela & David. This boutique tiny cabin was thoughtfully designed and lovingly named in honor of my parents. A refined experience where minimalist design meets ultimate comfort, tucked away in a peaceful cedar forest near the volcanoes. Relax as a couple or bring the whole family to this sanctuary.

Guest favourite
The living area features a cozy seating arrangement with a black sofa and a wooden dining table. A rustic fireplace is framed by exposed wooden beams. The space opens to a brick patio, enhancing the indoor-outdoor connection.
Home in Del Carmen
4.94 out of 5 average rating, 108 reviews

Hermosa Casita Coyoacán

Disfruta Coyoacán caminando, hospedándote en un Nuevo Departamento con Jardín Privado. Situado a unos pasos de todas su atracciones. EL HISTÓRICO COYOACÁN ASÍ COMO EL NUEVO Y ESPECTACULAR CENTRO COMERCIAL TORRE MITIKAH. Con muchas tiendas y Restaurantes

Top guest favourite
The exterior of a two-story house is surrounded by lush greenery and vibrant planters. A small terrace features a white umbrella, where a person is seated, enjoying the garden view. A paved pathway leads to the entrance, enhancing the welcoming atmosphere.
Loft in Del Carmen
4.95 out of 5 average rating, 254 reviews

Loft Coyoacan Viveros (Bow)

A super special and very cozy place in the heart of Coyoacán! right next to Coyoacán nurseries, on Melchor Ocampo street Ideal for a couple with or without children who want to enjoy a pleasant stay or a good walk through the wonders of Coyoacán :)

Popular amenities for Santa Cruz holiday rentals

  1. Airbnb
  2. Mexico
  3. Santa Cruz