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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
The exterior of the house features a two-story design with a combination of brick and white walls. Large windows provide natural light, while blue awnings add a touch of color. A covered parking space is visible, along with a playground area in the foreground.
Home in Xochimilco
4.85 out of 5 average rating, 108 reviews

GranCasa Colonial Xochimilco Est Azteca Trajineras

Soy súper anfitrión, 14p +2p en sofás, lleva a toda la familia o amigos en una excursión diferente, paquetes a trajineras c/alim y beb, cerca bosque Nativitas,caballo, artesanías, Vta de plantas, salida a Oaxtepec Morelos, excursion ahorra alojamiento y traslados caros. Internet, cable, tv,2 cajones autos medianos gratis previa confirmación. descuentos en más de 1 semana. Conciertos en Estadio Azteca a 25min aprox. 8camas: 1 king, 1 Queen, 3matrimoniales y 3individuales y hasta 2 Sofás para 2p

Top guest favourite
The building presents a modern design with a prominent use of green glass. The façade is enhanced by colorful window coverings, flanked by two parked cars. A clear sky serves as a backdrop, highlighting the structure's height and the surrounding area.
Flat in Ciudad Nezahualcóyotl
4.98 out of 5 average rating, 256 reviews

Seguridad y Confort en Edo.MEX

Departamento con gran comodidad, espacio y seguridad, cuenta con circuito cerrado, puerta de entrada principal automática, alarma contra robo, monóxido de carbón e incendio, excelente calidad de internet y Smart Tv. Cuenta con sistema de iluminación con 3 tonalidades: Luz blanca, semicálida y cálida, apta para el estudio y el descanso. Las escaleras centrales cuentan con pasa manos, antiderrapante, iluminación con sensor. Cocina y baño equipados. Ubicación practica con servicios disponibles.

Top guest favourite
Home in Del Carmen
4.95 out of 5 average rating, 392 reviews

Casa José Clemente Orozco Coyoacán

Located in Coyoacán, typical Mexican neighborhood surrounded by markets, museums and historical buildings, a few blocks from Museu Frida Khalo, this house was the first studio for the painter and muralist José Clemente Orozco, who designed and build it between 1921 and 1923. All the bedrooms have their own bathroom and the main suite has a king-size bed, Smart TV and a terrace. It has a big and beautiful garden and a work space with its own terrace too. The garden is shared by 2 houses.

Guest favourite
A cozy bedroom features a spacious bed with a soft grey headboard and decorative cushions. A sleek bedside lamp provides gentle illumination, while modern wooden cabinetry adds warmth to the space. A grey armchair is positioned nearby, complemented by delicate white flowers in the foreground.
Loft in Tlalpan
4.88 out of 5 average rating, 955 reviews

Punto Lofts Periférico Sur

Punto Lofts Periférico Sur es un concepto moderno con 18 lofts totalmente equipados, ideales para estancias cortas o largas. Cada loft aloja hasta 3 personas y cuenta con cama Queen Size y sofá cama, ofreciendo comodidad y descanso. Disfruta de recepción 24/7, acceso con llave digital y altos estándares de limpieza y seguridad. Ubicado sobre Periférico Sur, frente al Estadio Azteca, con fácil acceso a hospitales, restaurantes y centros comerciales.

Guest favourite
Flat in Condesa
4.84 out of 5 average rating, 1877 reviews

Chic & Equipped Apt | Rooftop+Gym+B/Center+Lounge

This stylish apartment in the heart Roma Norte and Condesa offers the perfect setup for digital nomads—ultra-fast Wi-Fi, a sleek workspace, and steps from the trendiest cafés, restaurants, and nightlife. Enjoy top-tier amenities: a business center, a full gym, a game room, and a rooftop with stunning views. Stay productive, stay inspired, and experience CDMX like a local.

Top guest favourite
A charming outdoor patio is surrounded by vibrant greenery and a blue-walled house. A round glass table is complemented by six white metal chairs, creating an inviting space for dining or gathering. Potted plants and flowers add color to the serene environment.
Home in Coyoacán
4.97 out of 5 average rating, 109 reviews

Casa Omac | Colonial house with two patios

Typical colonial house, located in the most picturesque and emblematic street of Coyoacán. The style is reminiscent of Frida Kahlo's Blue House, which is a few minutes' walk away. Organized around a large internal patio, the house has 5 double rooms and can host up to 10 people, making it ideal for groups and families.

Top guest favourite
Guest house in Xochimilco
5.0 out of 5 average rating, 52 reviews

Jardín y hermosa casa para eventos y estancia

Jardín de eventos Camino Real Desconecta de tus preocupaciones en este espacio tan amplio y sereno. Ideal para todo tipo de eventos, fiestas infantiles, reuniones, bodas, eventos corporativos, talleres, cursos de yoga o cualquier otro ejercicio o actividad al aire libre 🍃🌿🌤️

Guest favourite
A welcoming entrance is displayed with a wooden door featuring decorative glass. Large windows with striped curtains allow natural light to brighten the space. Potted plants line the area, contributing to a serene ambiance. A small decorative item is hung next to the door.
Home in Tláhuac
5.0 out of 5 average rating, 49 reviews

Bonita casa en zona oriente

Alojamiento ideal para grupos pequeños, ambiente tranquilo y familiar. Pensado para estancias cómodas y con todos los servicios. Cerca del metro Nopalera, del Hospital General del ISSSTE, del Hospital General de Tláhuac, de la Universidad Marista y de plaza Las Antenas.

Superhost
A well-maintained entryway is framed by neatly trimmed grass and flower beds. The white front door is flanked by large windows, allowing natural light to enter. A soft path of concrete slabs leads to the entrance, accented by vibrant greenery and colorful flowers.
Home in San Martín Cuautlalpan
4.82 out of 5 average rating, 17 reviews

Descanso fresco y acogedor.

Relájate con toda la familia en este alojamiento donde la tranquilidad se respira a 35 minutos hacienda panoaya, bosque de los arboles de navidad, restaurantes campestres, plazas comerciales, dentro de la unidad juegos, canchas.

Top guest favourite
A spacious living area features a light grey sofa adorned with decorative pillows. An intricate glass coffee table sits on a tiled floor, reflecting light from large windows framed by brick arches. Warm curtains complement the vibrant wall art and ceramic plates displayed nearby.
Home in Coyoacán
4.96 out of 5 average rating, 168 reviews

Casa Colonial con jardín en el Centro de Coyoacán

Casa colonial de lujo, a 350m del Centro de Coyoacan. La casa cuenta con jardín y terraza. Nos esmeramos para que tu estancia sea perfecta. Si tu estancia es larga tenemos servicio de limpieza incluido.

Guest favourite
A spacious sleeping area features a large bed with neutral bedding and a blue throw blanket. Wooden nightstands are placed on either side, while an open shelving unit stands in one corner. Soft lighting enhances the calm atmosphere against the gray walls.
Apartment in Iztapalapa
4.93 out of 5 average rating, 553 reviews

HB Flat (2 BR) 15min Airport/10min Estadio GNP

Departamento completo a 15 min del aeropuerto, 10 min del Foro Sol, Palacio de los Deportes y Autodromo Hermanos Rodriguez en coche. 2 recámaras con escritorio, baño, cocina y sala - comedor.

Superhost
A lush field of nopales occupies the foreground, displaying a vibrant green landscape. In the background, rustic red-roofed cabins are visible against a backdrop of rolling hills and a wide sky, offering a glimpse of the tranquil countryside.
Cabin in San Lorenzo Tlacoyucan
4.84 out of 5 average rating, 37 reviews

Cabaña de descanso en Milpa Alta

🤠 Disfruta del campo en la reserva ecológica de Milpa Alta, entre nopaleras y magueyes convive con la gente del campo y disfruta de hermosas vistas al valle de México.

Popular amenities for Santa Cruz holiday rentals