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Holiday rentals in Santa Isabel District

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Isabel District

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
Home in La Guaira
5 out of 5 average rating, 9 reviews

Apt near sea+Parking+TV+AC+Kitchen+WiFi@La Guaira

✔️ SuperAnfitrión Verificado ¡Tu estadía estará en las mejores manos! 🚨Envíanos un mensaje con la palabra DESCUENTO y pregunta por promociones especiales 📍 Apartamento en Provincia de Colon, Panamá 🇵🇦 🏡 Espacio limpio, cómodo y seguro, con excelente ubicación 🧼 Dotado con insumos y productos de limpieza Durante tu reserva, tu Airbnb cuenta con: 🌐 Wifi 📺 TV 🍳 Cocina ❄️ A/C 🌊 Cercano a la playa 🚗 Parqueo 👉Envíanos un mensaje con la palabra DESCUENTO y pregunta por promociones

An aerial view shows a property situated by the water, featuring red-roofed cottages and a grassy yard. Kayaks are visible in the water, along with seating areas under palm trees. A smooth pathway leads down to the water's edge, offering direct access for guests.
Home in Viento Frío
5 out of 5 average rating, 8 reviews

Casa Canalú

Disfruta de los sonidos del mar cuando te quedes en este lugar único. El mar frente a la propiedad es como una piscina natural. La propiedad está ubicada a seis metros del mar por lo que siempre podras disfrutaras de la brisa marina desde una hamaca. A los que les gusta cocinar contaran con una cocina totalmente equipada. Las 3 confortables habitaciones, que son separadas una de otra, cuentan con Aire Acondicionado, abanicos y wifi. Estacionamiento para varios carros. Bote pedal,Kayak,Canoa

An aerial view showcases a rustic cottage surrounded by lush palm trees, located near a sandy beach. The gentle waves of the ocean are visible, along with several red-roofed structures nestled within the greenery, creating a serene coastal atmosphere.
Cottage in Palenque
4.87 out of 5 average rating, 94 reviews

Beachfront House in Caribbean sandy beach

Enjoy this rustic and cozy cottage with its almost private beach surrounded by beautiful palm trees along the whole area. With 2 oceanview bedrooms, 2 full bathrooms and a third bedroom in a mezzanine. Has a patio with a built in uruguayan parrilla, ideal for BBQs. Step in beautiful white sand and bath in crystal clear water. Coconut breakfasts watching the sunrise become a routine in this paradise. - This is a rural setting. Not a 5 star hotel. Insects and small animals can be around.

Guest favourite
Villa in Palenque
5 out of 5 average rating, 29 reviews

All 5 Stars Reviews Caribbean Retreat Beach Front

If you are looking for a place to relax this is it. Located 2 and a half hours away from Panama City, this is a place to enjoy the beach while listening to the sound of the waves. In a luxurious villa. The place is ideal for families with kids. Very save with shallow waters as well with deeper areas. Our large gardens are also ideal for kids to play. Kayaks are included. We have high speed internet, which will allow you to work from here. We also have kayaks and paddle boards for our guest.

Home in Playa Chiquita
5 out of 5 average rating, 7 reviews

Caribbean Jungle Beach House

Secluded loft beach house on 7 hectares of jungle with pristine beach. Enjoy the peaceful tranquility of coconut palm tree covered golden sand beach with shallow warm water great for swimming and body surfing. Lounge chairs, barbecue, kayaks, snorkel masks, boogie boards, hammocks and a fire pit for beach bonfires under the starry night sky all available. Great for families, couples or groups of friends. Delicious Panamanian food made to order on site. Tent camping (glamping) also available.

Superhost
Home in La Guaira
4.73 out of 5 average rating, 37 reviews

Bella Casa, Mar Caribe, JuanGallego (waterfront)

Hermosa Casa de Playa, frente al mar caribe, para descansar y relajarse al 100%. La Casa cuenta con una ubicación privilegiada, mantiene 4 habitaciones (una de ellas cuenta con una mampara para dividir de la sala y ampliar esa área en caso que se desee), sala, comedor, terraza privada, frente a Isla Grande. 4 habitaciones. 3 tienen TV con cable y una TV extra en la sala. Todas con con Aire Acondicionado. Cuenta con 2 baños completos. Cocina equipada y lista para disfrutar y Wifi

Home in Palenque
4.61 out of 5 average rating, 38 reviews

Lagoon & Oceanfront Retreat · Infinity Pool

Welcome to our beachfront paradise in Palenque, Colón, Panama! Nestled along the stunning coastline, this spacious and inviting house offers the perfect retreat for your group getaway. With direct beach access, you'll wake up to the soothing sounds of the waves and the breathtaking views of the ocean right outside your doorstep. The house is located by the beach, in a forest area. You may experience presence of insects during night-time. Insect repellent is always recommended.

Chalet in Viento Frío
5 out of 5 average rating, 4 reviews

Chalet espacioso junto al mar

Vivienda dúplex. Ideal para eventos o grupos en estadías cortas. Acondicionada para familias en estadías largas. Playa sin erizos o piedras. Olas y brisa de mar de un lado; y del otro lado, el centro del pueblo, el parque y una iglesia centenaria. Pueblo con celebraciones anuales como "el día de la raza". Puedo darte oferta para 4 personas, para una sola noche o para menos.

Guest favourite
The two-story house is positioned just steps from the water's edge, surrounded by lush greenery and palm trees. A spacious terrace extends from the upper floor, providing a view of the serene landscape. The natural stone shoreline complements the tranquil setting.
Flat in Colón
4.93 out of 5 average rating, 107 reviews

KasaKai garden floor - amazing views over the sea

Caribbean downstairs apartment with amazing sea view. Surrounded by wildlife. This property has a private access to the Caribbean Sea. The house is situated over a 2 miles long reef. Amazing snorkeling, there are many naturals pools into the reef where you can snorkel. Ideal for kids! There is a jungle behind the house which makes that you will hear the monkey from the house.

Guest favourite
An aerial view showcases the property nestled between two natural beaches, surrounded by lush greenery. Calm waters and rocky formations are visible nearby, alongside beachside features that highlight the area's tropical environment.
Villa in Palenque
5 out of 5 average rating, 10 reviews

Beach Front House Surrounded by 2 Private Beaches

La propiedad esta rodeada de dos playas naturales. Preserva una selva primaria con múltiples clases de arboles endémicos del área que sirven de alimento a los aulladores, titis, perezosos y muchas aves en especial tucanes que vienen a comer uvitas tropicales. Tenemos un camino interno para observar la selva. Entre Marzo-Mayo y Agosto-Oct se observa la migración de aves.

A welcoming entrance to Casa Guaymar is framed by lush greenery and vibrant plants. The structure features a spacious porch, highlighted by the colorful sign overhead. Large glass doors allow for a view of the inviting interior and surrounding landscape.
Home in Juan Gallego
4.63 out of 5 average rating, 24 reviews

Casa frente a Isla Grande

Descubre el paraíso caribeño en Casa Guaymar, una casa frente al mar con piscina, bar, hamacas y una vista espectacular a Isla Grande. Perfecta para grupos de hasta 16 personas, con espacios amplios, 4 habitaciones con camas king y 8 colchones individuales. Vive la experiencia de cruzar a la isla desde la misma orilla de la casa. Ideal para desconectar y disfrutar.

Home in Palenque
4.71 out of 5 average rating, 7 reviews

Casa Palenque Panamá

Disfruta de una espectacular casa frente al mar, ideal para grupos y familias de hasta 14 personas. Relájate con vistas directas a la playa, amplios espacios interiores y exteriores, y todas las comodidades para una estancia inolvidable. Perfecta para descansar, convivir y crear recuerdos únicos con el sonido del mar como fondo. Somos pet friendly.

Popular amenities for Santa Isabel District holiday rentals