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Holiday rentals in Santiago

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Top-rated holiday rentals in Santiago

Guests agree: these stays are highly rated for location, cleanliness and more.

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A bright and airy room features two full-size beds with crisp white linens and decorative pillows. A wooden dining table with four chairs is positioned nearby. Fresh towels are neatly arranged on the beds. A small kitchenette is subtly integrated into the space.
Flat in Los Canelos
4.72 out of 5 average rating, 46 reviews

Salamanca Loft

Este hermoso apartamento esta ubicado en el centro de todo Panamá en la hermosa provincia de Herrera, vía interamericana, a pocos minutos de varias ciudades como Chitré, Aguadulce y Santiago. En un ambiente tranquilo, rodeado de árboles. Si corren con suerte podrán observar desde lejos las hermosas iguanas que se pasean por las ramas mas altas. Pueden apreciar al caer la tarde una hermosa puesta del sol. Justo al frente, hay cafetería, también hay pizzerías a domicilio y restaurantes.

A spacious living area features large windows that provide panoramic views of the surrounding mountains and forest. Comfortable seating is arranged around a coffee table, and a television is mounted on the wall. A staircase leads to the upper level.
Cabin in Chepo
4.5 out of 5 average rating, 6 reviews

Cabin at El Montuoso Reserve.

Escape into serenity with your loved ones or enjoy a romantic retreat for two at Arrues Mountain Retreat, nestled in the picturesque Chepo Las Minas region of Panama, specifically in the heart of La Reserva Forestal El Montuoso. Here, tranquility is not just a promise but an immersive experience. Surrounded by the pristine beauty of Montuoso's nature, the climate is temperate, creating the perfect backdrop for a peaceful getaway with an awe-inspiring panorama of the majestic mountains.

Superhost
Home in Santiago
4.81 out of 5 average rating, 21 reviews

Casa a minutos de Santiago, U Latina, HospChichoF.

Spacious, comfortable and fully equipped house in a strategic location in Santiago. Perfect for all types of guests: families, business travelers, students, people coming to medical appointments or those looking for a quiet and accessible space. The house is located very close to Dr. Chicho Fábrega Hospital, Clínica Norte, U.Latina, Oxford School, shops, supermarkets, pharmacy, restaurants, and minutes from downtown Santiago. A safe place for short and long stays.

Guest favourite
Home in Canto del Llano
4.88 out of 5 average rating, 17 reviews

Peaceful home w/ spacious living & office area

Spacious and peaceful home in a safe area of Santiago. 4 bedrooms (ideal for families and groups), bright living-dining area and large kitchen to share with family or friends, plus a private office for working comfortably. High-speed Wi-Fi, air conditioning and fans in all rooms, fully equipped kitchen, washer/dryer, and safe for valuables. Self check-in with smart lock, parking for several cars, and a coffee station with board games and karaoke.

A spacious studio is presented, featuring a comfortable sofa and a queen bed with an elegant headboard. A flat-screen TV is mounted on the wall opposite. A small table and chairs are arranged near the sofa, providing a cozy seating area within the bright space.
Serviced apartment in Santiago
5 out of 5 average rating, 4 reviews

Studio Hotel Gran David

This studio is located behind the Hotel Gran David, which is located in a very convenient location (Carretera Panamericana). However, this studio is located on a very quiet area at the back part of the hotel. Although the studio has an independent entrance to that of the hotel, you can still use all the amenities of the hotel (swimming pool and gym), and have easy access to the hotel's two restaurants, pool bar and bar.

A spacious living area is presented with a light-toned sofa adjacent to large windows, providing natural light. A metal shelving unit adorned with plants stands in the center, complemented by a simple round mirror on the wall. A wooden table and chair add functionality to the space.
Apartment in Santiago
4.72 out of 5 average rating, 18 reviews

2A Apartment

Accessible apartment in downtown Santiago, located 300 meters from the Transportation Terminal and within walking distance of supermarkets and businesses. With a good layout, fresh and bright, and with all the basic amenities. The apartments provide a harmonious balance in the middle of the characteristic comings and goings of the center, perfect for stays of families, friends, professionals, couples.

A small dining area is featured with a round table and two folding chairs. Large windows offer views of lush greenery outside, while sheer white curtains partially filter natural light.
Flat in Santiago
4.78 out of 5 average rating, 9 reviews

d'rosas apartments 3PB

Discover comfort in our cozy accommodation in the heart of Santiago, Veraguas. Just a 5-minute walk from the city center, you'll enjoy a well-equipped space that includes all the necessary amenities for a relaxing stay. Ideal for exploring the local culture and resting after a day of adventures. We look forward to seeing you!

Guest favourite
Serviced apartment in Santiago
4.88 out of 5 average rating, 8 reviews

Accommodation in Santiago Centro

Enjoy easy access to everything from this perfectly located accommodation in downtown Santiago, 2 minutes from the cathedral church, park, and the central avenue. Fresh and comfortable on the ground floor of a property with a large terrace with access to the courtyard surrounded by nature.

Guest favourite
A modest exterior view features a white building with dark windows and a welcoming black door. Lush greenery surrounds the entrance, and well-maintained stone pathways lead to the door, highlighting the peaceful outdoor setting.
Home in Santiago
4.86 out of 5 average rating, 21 reviews

2 bedroom house in Santiago

centric, well located, walking distance to downtown. Near the Panama Canal Museum, park Juan Demostenes Arosemana, and the Santiago Cathedral Juan Pablo Apostol. A few meters from central avenue.

A modern one-story home with a flat roof features large windows framed by wooden slats. A well-manicured lawn surrounds the entrance, while a concrete pathway leads to the front door. The exterior is painted in neutral tones, contributing to its contemporary design.
Home in Santiago
4.78 out of 5 average rating, 112 reviews

3BD, 2BTHS, furnished house

House with 3 bedrooms, 2 bathrooms, central, furnished, security booth, kitchen, automatic washing machine, A/A, Wi-Fi, cable TV, new construction in a nice residential area.

A modern tiny house constructed from a shipping container stands with a spacious rooftop overhang. Large glass doors provide access to the interior, while small planters frame the entrance. Surrounding greenery adds a natural element to the setting.
Shipping container in El Espino de Santa Rosa
4.37 out of 5 average rating, 30 reviews

Comfort house 8

Tiny house, 20" container, fully adapted to rest and have a pleasant time. With a pool, from the complex where we are, very large and surrounded by nature.

Home in Santiago
New place to stay

A metros de Mall, Supermercados, Hospital, etc.

Acogedor, espaciosa, wifi, a metros dé Pricemart, farmacias, restaurantes, a 40 minutos de Playa Torio, para familias y grupos de amigos

Popular amenities for Santiago holiday rentals

  1. Airbnb
  2. Panama
  3. Veraguas Province
  4. Santiago