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House holiday rentals in Santo Domingo Este

Find and book unique houses on Airbnb

Top-rated house rentals in Santo Domingo Este

Guests agree: these houses are highly rated for location, cleanliness and more.

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Guest favourite
Home in Los Frailes
4.95 out of 5 average rating, 60 reviews

High-Class Home, Hot Water, Pool, Patio & Security

We offer the best space with the best amenities to spend time with family and friends or celebrate your birthday in RD: • Hot water🛁 • Visitors are allowed🫂 • Air Conditioning in all areas❄️ • Dryer machine 👕👖 • Only minutes away from Avenida España, SDQ airport, beaches, retail stores, banks, malls, restaurants, and clubs ✈️🏖️🛍️🏧🍻 • Private pool, spacious backyard, patio furniture, dominos & BBQ 🏊‍♀️🥩 • Perfect for families, couples, & friends 👣 • 5G Wifi 🛜 • Private bedrooms 🛏️

Top guest favourite
A spacious living area features a light-colored sofa adorned with decorative pillows. A coffee table with floral arrangements complements two blue accent chairs nearby. Large windows allow natural light to fill the room, enhancing the bright, airy atmosphere.
Home in Los Prados
4.99 out of 5 average rating, 136 reviews

Casa Serena: cozy, modern, spacious and peaceful

Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.

Guest favourite
A serene outdoor space features a small pool surrounded by light-colored stone steps. Green walls and natural light are provided through a skylight, enhancing the ambience. Tropical plants frame the area, contributing to a private and refreshing atmosphere.
Home in Ciudad Colonial
4.89 out of 5 average rating, 141 reviews

Colorful Caribbean house in the Zona Colonial

Enjoy a marvelous stay at this gorgeous, colorful and spacious home at the Zona Colonial. Light, airy rooms and amazing private outdoors create a unique caribbean flair. Relax in the tropical garden...refresh yourself with a dip into the tiny pool…dine under the stars or enjoy the amazing view of the San Francisco monastery ruins from the balcony. The famous Plaza de España is a few steps away and all the historical sites, museums, restaurants, cafés and bars are within easy walking distance.

Guest favourite
A modern living area is presented with white leather seating and a glass coffee table. Accent lights illuminate built-in shelving displaying decorative items. A fan and a television are positioned within the space, while dark curtains frame large windows.
Home in Los Frailes
4.88 out of 5 average rating, 260 reviews

casa bella 3 camas 1 king +2 twin airport 15min.

Relájate en este espacio tranquilo,elegante y seguro aeropuerto (15 minutos) playas ,calles principales Supermercados cerca (zona súper tranquila segura y muy confortable ) 1–incluimos servicio de lavado y secado 2–wifi 3–Tv Smart 55 sala y 65 hab principal 4–puerta principal inteligente con clave 5–muebles en leather 6– cama principal king size 7–aire acondicionado en la principal 8–parqueo techado y cerrado 9–inversor de Luz 24 horas incluido Soy súper atento con mis huéspedes

Guest favourite
A welcoming living area features a comfortable wooden sofa adorned with green cushions, accompanied by two wooden chairs. A round wooden coffee table is centered on a patterned blue and white rug, while a potted plant adds a touch of greenery near a window.
Home in Ciudad Colonial
4.85 out of 5 average rating, 123 reviews

New - 3 Bd House Zona Colonial + Private Rooftop

🌴🥥 Welcome to the perfect oasis in the Dominican Republic. We are so happy to host you ! We are centrally located in La Zona Colonial, the historic central neighborhood of the Dominican Republic's capital, Santo Domingo. It is the oldest continuously inhabited European-established settlement in the Americas. We are steps away from restaurants, night life, bars, museums and landmarks. Casa Altagracia is an eclectic, unique and curated house welcoming families, couples and friends.

Top guest favourite
A bright and airy entrance leads to a serene outdoor area with a pool. The space is framed by modern glass walls, showcasing inviting seating and greenery. Natural light filters through, enhancing the layout that connects indoor and outdoor living.
Home in Ciudad Colonial
5 out of 5 average rating, 51 reviews

Stunning villa in Zona Colonial

Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

Guest favourite
A bright living area features a comfortable sofa adorned with decorative pillows and a coffee table. Natural light filters through large windows, highlighting the outdoor greenery. A ceiling fan provides airflow, and the entrance door opens to a welcoming patio space.
Home in Villa Faro
4.8 out of 5 average rating, 122 reviews

Spacious house, gated community of Alma Rosa I

Esta casa se encuentra en un residencial cerrado y muy seguro. Està centralmente ubicada; a sólo 20 minutos del aeropuerto de Las Americas y a pocos minutos de los lugares más icónicos del gran Santo Domingo. También puede trasladarse caminando a los restaurantes, supermercado y centros comerciales del area. Ofrecemos check- in temprano y check-out tarde, segun las reservaciones que tengamos pendientes.

Top guest favourite
A covered terrace features a wooden floor, surrounded by potted plants. Four chairs with colorful cushions face a wooden table. A hammock and a cozy blue chair are positioned nearby, with an open view of the rooftops in the background.
Home in Ciudad Colonial
4.96 out of 5 average rating, 113 reviews

Charming Old City Corner House

This charming 2 bedroom corner house is located in the walled colonial city of Santo Domingo. It’s only a few steps away from historical attractions, museums, restaurants, coffee shops, bars, souvenir shops, bakeries, supermarket and lovely squares. The beautiful covered terrace, overlooking the rooftops of the old town with living area, hammock and BBQ is perfect for a relaxing afternoon or evening.

Guest favourite
A serene outdoor area features a private swimming pool bordered by stone walls. Potted plants are placed strategically around the pool, enhancing the tranquil atmosphere. A shaded seating area is visible under a blue canopy, providing a space for relaxation.
Home in Santo Domingo Este
4.75 out of 5 average rating, 163 reviews

Casa Escondidas is close to everything you need.

Casa completa con piscina TOTALMENTE PRIVADA y no compartida, ideal para disfrutar en familia en un ambiente seguro y tranquilo en Santo Domingo Este. A minutos de Playa Juan Dolio, Boca Chica, Parque Colón, Los Tres Ojos y el Acuario Nacional. Supermercados, restaurantes y la Avenida España muy cerca, incluyendo uno de los mejores restaurantes de Santo Domingo, todo listo para descanso y diversión.

Guest favourite
A modern living area features two armchairs in rose color opposite a sleek marble coffee table. A television is mounted on the wall, and light filters through sheer curtains, illuminating the space. Decorative elements include a vase of flowers on the side table.
Home in El Cacique
4.94 out of 5 average rating, 125 reviews

Cozy & Beautiful City Center House with Jacuzzi

The House is located in " El Cacique", one of the safest areas in the city, with access to Malecón ( Caribbean Sea), supermarket and clinics 5 minutes walk, access to Mirador Sur park, and 15-20 minutes from the most prestigious shopping centers in the city. Located approximately 40 minutes from the airport and 14 minutes from Zona Colonial.

Guest favourite
Home in Santo Domingo Este
4.95 out of 5 average rating, 98 reviews

Luxury house in the East Zone

Spacious luxury house with 2 levels, ideal for being with a partner, friends or family. It has all the necessary amenities for a pleasant and luxurious stay. Located in the eastern area, 15 minutes from Las Américas Airport. 2 minutes from Bravo Avenida Hípica and 5 minutes from Avenida Ecológica.

Guest favourite
A private outdoor space features a sparkling pool surrounded by blue mosaic tiles. A shaded gazebo with wooden beams offers comfortable seating, ideal for relaxation. Lush tropical plants frame the area, enhancing the overall tranquility of the setting.
Home in El Cacique
4.85 out of 5 average rating, 108 reviews

Beautiful City Center House [Private Jacuzzi]

Cozy home in the National District, located in a quiet area near the Malecón. In our home, you can relax in the jacuzzi during the day and enjoy the evenings with a delicious barbecue in the private patio. Remember to the Read the House Rules. Thank you! (at the bottom of the listing).

Popular amenities for house rentals in Santo Domingo Este

When is the best time to visit Santo Domingo Este?

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Avg. price$77 SGD$77 SGD$77 SGD$74 SGD$70 SGD$74 SGD$70 SGD$72 SGD$77 SGD$72 SGD$77 SGD$77 SGD
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Quick stats about house rentals in Santo Domingo Este

  • Total holiday rentals

    Explore 610 holiday rentals in Santo Domingo Este

  • Nightly prices starting at

    Santo Domingo Este holiday rentals start at $13 SGD per night before taxes and fees

  • Verified guest reviews

    Over 10,630 verified reviews to help you choose

  • Family-friendly holiday rentals

    330 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 180 rentals that welcome pets

  • Holiday rentals with a pool

    120 properties feature pools

  • Rentals with dedicated workspaces

    190 properties have a dedicated workspace

  • Wifi availability

    560 of Santo Domingo Este holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Santo Domingo Este rentals

  • 4.6 Average rating

    Santo Domingo Este stays receive an average rating of 4.6 out of 5 from guests

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