
House holiday rentals in Santo Domingo
Find and book unique houses on Airbnb
Top-rated house rentals in Santo Domingo
Guests agree: these houses are highly rated for location, cleanliness and more.

High-Class Home, Hot Water, Security, Pool & Patio
We offer the best space with the best amenities to spend time with family and friends or celebrate your birthday in RD: • Hot water🛁 • Visitors are allowed🫂 • Air Conditioning in all areas❄️ • Dryer machine 👕👖 • Las Americas mins away from Av. España, SDQ airport, beaches, retail stores, banks, malls, restaurants, and clubs ✈️🏖️🛍️🏧🍻 • Private pool, spacious backyard, patio furniture, dominos & BBQ 🏊♀️🥩 • Perfect for families, couples, & friends 👣 • 5G Wifi 🛜 • Private bedrooms 🛏️

Casa Serena: cozy, modern, spacious and peaceful
Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.

New - 3 Bd House Zona Colonial + Private Rooftop
🌴🥥 Welcome to the perfect oasis in the Dominican Republic. We are so happy to host you ! We are centrally located in La Zona Colonial, the historic central neighborhood of the Dominican Republic's capital, Santo Domingo. It is the oldest continuously inhabited European-established settlement in the Americas. We are steps away from restaurants, night life, bars, museums and landmarks. Casa Altagracia is an eclectic, unique and curated house welcoming families, couples and friends.

Stunning villa in Zona Colonial
Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

"Peter's Green Villa"
"Si quieres alejarte del ruido de la cuidad y conectarte con la naturaleza, este alojamiento esta pensado para ti, podrás disfrutar con toda tu familia y amigos, de una encantadora villa rodeada de naturaleza y hermosas vistas al horizonte. Un lugar simplemente hermoso donde podrás relajarte y escapar de la rutina diaria." Es para personas aventureras que les gusta la privacidad y tranquilidad de estar alejados de la ciudad!!

Luxury House Private Pool | Casa #9
Descubre una moderna villa diseñada para disfrutar y relajarte. Cuenta con piscina privada, área de BBQ, espacios amplios y elegantes, cocina totalmente equipada, comedor, sala de doble altura con abundante luz natural y un balcón ideal para disfrutar el atardecer. Ubicada cerca del aeropuerto, playas y los principales puntos de interés, es el lugar perfecto para vacaciones, escapadas o viajes en familia y con amigos.

Casa espaciosa, residencial cerrado de Alma Rosa I
Esta casa se encuentra en un residencial cerrado y muy seguro. Està centralmente ubicada; a sólo 20 minutos del aeropuerto de Las Americas y a pocos minutos de los lugares más icónicos del gran Santo Domingo. También puede trasladarse caminando a los restaurantes, supermercado y centros comerciales del area. Ofrecemos check- in temprano y check-out tarde, segun las reservaciones que tengamos pendientes.

Charming Old City Corner House
This charming 2 bedroom corner house is located in the walled colonial city of Santo Domingo. It’s only a few steps away from historical attractions, museums, restaurants, coffee shops, bars, souvenir shops, bakeries, supermarket and lovely squares. The beautiful covered terrace, overlooking the rooftops of the old town with living area, hammock and BBQ is perfect for a relaxing afternoon or evening.

Your 2BR House + Terrace in the Colonial Zone
Feel the history in this authentic Colonial house from the XVI century with all the modern amenities you will need to make your trip unforgettable. Enjoy a walk to history in the oldest city of America. Visit impressive cultural sites, exquisite restaurants and bars. Have fun in a great night atmosphere. In just minutes you can be in the ocean shore ( malecon ) or in the Colonial promenade.

Heart of the colonial zone, Billini 54
At the very heart of the most exclusive part of the colonial city where all the fun and interesting activities take place. This beautiful one-bedroom apartment is on the first floor of a small building next to the colonial gate 4D cinema, electric bike rentals, beer market, food markets, historical landmarks, exclusive boutiques, galleries, restaurants and bars.

Cozy & Beautiful City Center House with Jacuzzi
The House is located in " El Cacique", one of the safest areas in the city, with access to Malecón ( Caribbean Sea), supermarket and clinics 5 minutes walk, access to Mirador Sur park, and 15-20 minutes from the most prestigious shopping centers in the city. Located approximately 40 minutes from the airport and 14 minutes from Zona Colonial.

Casa de lujo en Zona Oriental
Casa de lujo espaciosa de 2 niveles, ideal para estar con pareja, amigos o familia. Tiene todas las comodidades necesarias para una estadía placentera y lujosa. Ubicada en la zona oriental a 15 minutos del aeropuerto Las Américas. 2 minutos del Bravo Avenida Hípica y 5 minutos de la avenida Ecológica.
Popular amenities for house rentals in Santo Domingo
House rentals with a pool

Hm Tropical Villa-Luxury

Casita Colonial with pool

Casa Escondidas Cerca de todo lo que Necesitas.

Experience Ultimate Comfort | 4BR Home

Casa Aurelia + Pool + Sleeps 4

Private Pool, Fast Wi-Fi, A/C, Near Zona Colonial

Villa lujosa Boca Chica

Cheerful 4 bedroom home with pool and parking
Weekly house rentals

Casa del Orfebre circa 1525

Luxury, Classy Private House In Santo Domingo

Luxury Penthouse With Jacuzzi

Moderno apartamento en la Ciudad Colonial

Bonita villa RD

Casa acogedora en Santo Domingo

Casa completa a 5 min del Aeropuerto 3 habitacion.

Near Zona Colonial. Quiet charming home in Gazcue
Private house rentals

Casa Castellana

Villa Don Solano | Retiro Pacifico @ Lago De Reyes

villa yaya

Asombrosa casa con piscina en Santo Domingo

Acogedora casa en un segundo nivel

Elegant Luxury Home+ Rooftop Jacuzzi Zona Colonial

Casa en Santo Domingo

Exclusivo Townhouse de Lujo con Piscina
Destinations to explore
- Cabin rentals Santo Domingo
- Rentals with a hot tub Santo Domingo
- Rentals with an accessible-height bed Santo Domingo
- Rentals with a sauna Santo Domingo
- Ski-in/ski-out rentals Santo Domingo
- Tiny house rentals Santo Domingo
- Farm stay rentals Santo Domingo
- Loft rentals Santo Domingo
- Pet-friendly rentals Santo Domingo
- Apartment rentals Santo Domingo
- Guest house rentals Santo Domingo
- Townhouse rentals Santo Domingo
- Waterfront rentals Santo Domingo
- Hotel rooms Santo Domingo
- Family-friendly rentals Santo Domingo
- Bed and breakfasts Santo Domingo
- Rentals with breakfast Santo Domingo
- Flat rentals Santo Domingo
- Rentals with pools Santo Domingo
- Rentals with lake access Santo Domingo
- Boutique hotels Santo Domingo
- Private suite rentals Santo Domingo
- Aparthotel rentals Santo Domingo
- Villa rentals Santo Domingo
- Hostel rentals Santo Domingo
- Serviced apartment rentals Santo Domingo
- Rentals with beach access Santo Domingo
- Holiday home rentals Santo Domingo
- Beachfront rentals Santo Domingo
- House rentals Dominican Republic
- Things to do Santo Domingo
- Workouts Santo Domingo
- Cultural tours Santo Domingo
- Outdoors Santo Domingo
- Things to do Dominican Republic
- Performances Dominican Republic
- Outdoors Dominican Republic
- Landmarks Dominican Republic
- Cooking Dominican Republic
- Water sports Dominican Republic
- Tastings Dominican Republic
- Workouts Dominican Republic
- Art workshops Dominican Republic
- Cultural tours Dominican Republic





