
Holiday rentals in Semmes
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Semmes
Guests agree: these stays are highly rated for location, cleanliness and more.

Downtown , Modern Spacious & Near I-10
Enjoy a little piece of Mobile, Alabama by staying at this centrally located townhouse near all the best restaurants and the hustle and bustle of downtown. This unique space is a minute from I-10 giving you easy access to the interstate and quick driving time to just about anywhere. Minutes from the convention center, cruise terminal, Washington Square, and the famous Callaghan's Irish Social Club. Spacious, clean, modern, and convenient are all descriptions for this cute, newly remodeled space.

Adorable 1-Bedroom Guesthouse in Spanish Fort
Enjoy a private space to call home during your Spanish Fort stay, cozy detached guest house with full bath, kitchenette, dinning space and closet space with private entrance. Amazing location only 10 minutes away from Mobile Bay and five rivers delta with the best fishing in the area. US-98 Causeway offers some of the most popular Cafe/Bars and amazing seafood, Italian and Mexican dinning on the Bay. Also within 5 minutes of shopping centers, 20 minutes from Fairhope and 45 to Pensacola Beach.

Cozy Home Minutes to Downtown
RELAX & UNWIND at this PEACEFUL, SPACIOUS & COZY Cottage located in the popular Midtown area of Mobile! Upon arrival you will feel right at home. You will find this cottage is very spacious equipped with a King size bed, Queen size bed, Full size bed, Master bathroom & Guest bathroom & a fully equipped kitchen! Enjoy a glass of wine, a good book or some family time outback in the peaceful backyard! A short commute to all the restaurants, bars & attractions! This cottage is the perfect getaway!

Peach & Pine Cottage - Pet friendly in Midtown
Peach & Pine Cottage, named for its color palette and featured tree, is our third listing! In this home, we embraced the retro energy with pops of mid-century modern throughout and paid homage to the fab fifties in almost every room. You’ll feel both comfortable and relaxed in a space filled with mixed metals, pastel colors, & plenty of lighting. As always, we want you & your pets to feel at home. Checkout our other properties, Magnolia Belle & the Oak Haven, to see the experience we provide!

Historic Midtown • Walkable • 5 Min to DT • WiFi
Centrally located in charming, walkable Midtown Mobile’s Old Dauphin Way Historic District, my home is just minutes from: 🎭 Mardi Gras parade route (2 mi), USS Alabama (5.3 mi), GulfQuest Museum (2.8 mi), Saenger Theatre (2.6 mi), LODA District (2.6 mi), Ladd-Peebles Stadium (0.8 mi), and Convention & Civic Centers (2.9 mi). 🏥 Near USA Health (2.5 mi) & Mobile Infirmary (3.2 mi). 🏖️ Dauphin Island (45 mins). ✈️ 15 mins to Mobile Regional Airport with quick access to I‑10/I‑65.

Three Notch Cutie
Your family will be close to everything at this centrally located home located in the Tillman's corner area of Mobile, AL. The house is approximately 1/4 mile from a new Dollar General and 3 miles from interstate I-10. In 2024 we did an interior renovation of the house, so that it now features LED lighting, freshly painted walls, new floors, new appliances, a tile shower, granite countertops, and brand new furniture. We ask that you take care of our investment. Thank you!

Cottage on Caroline
Welcome to Cottage on Caroline, a precious and happy home that is in Old Dauphin Way Historic District A neighborhood that is enjoying revitalization and value appreciation. The entire home was renovated. The ceilings are 10' and the hardwood floors are original and full of character. Huge fenced backyard. Dauphin St Entertainment District is a 5 minute walk away. The home also sits on the bike path and is a block and a half from the Mardi Gras parade route.

{B A Y} Quiet Midtown Retreat with King Bed
Please take a few minutes to read our reviews and hear why guests love our place so much... we work hard to provide a five star experience for every guest we host. We know you will love it too! *We offer weekly and monthly discounts* Our duplex is situated in a very friendly, walkable neighborhood. Starbucks is just a short stroll down the street. Walking distance to Aldi, Guncles gluten free bakery, and Soul Caffeine coffee shop.

Fenced Bkyd- Near Hospitals & USA College. 2q beds
Welcome to the "Comfy Cottage" in the ❤️ of Mobile, Al. Comfort at yout finger tips! The Popular Dauphin Isand Beach is only 45min away. Close to everything: hospitals, golf, colleges and shopping. Biloxi, Mississippi and Gulf Shores are just an hour away. 15min to Downtown. Great for contractors, nurses, families, friends or just you as an individual. Guests have said this is a very comfortable and quiet home.

Haven on Hamilton
Cozy, private guest suite convenient to the interstate, airport and great local restaurants. Located just half an hour from Dauphin Island and historical downtown Mobile. Local attractions include the USS Alabama, Mobile cruise terminal, and more. You can have the quiet, country feel with all the convenience of city living.

Live Oak Loft—Historic Midtown
A light filled, cozy guest suite with a private entry and beautifully landscaped courtyard in historic mid-town Mobile, Alabama. Located a few miles from downtown with locations such as the Mobile Convention Center, Cruise Terminal, Battleship Park and Mardi Gras.

✦1st Flr Suite✦ Walk to Pizzeria/Dining/Bus/Campus
Hi and welcome! The stay is a 1st Floor guest suite only you have access to and separated from the rest of the house. It is located across from the USA campus and is also a short walk to many restaurants, a city bus stop, a post office, dry cleaners, and more.
Popular amenities for Semmes holiday rentals
Other great holiday rentals in Semmes

Top Location! Close to USA, Fenced yard, 2 Patios!

Coastal Guest House

Oak Hill: 2 Acres w/ 4 Bedrooms

The Bare Minimum Bachelor Pad 3 bed/2 baths

Peaceful Backyard Suite

Spacious 4 bedroom/2 bath in Sweet Home Alabama

Cobblestone Cottage

Modern Cottage w/Cabana-15 min to Downtown
Destinations to explore
- Florida Panhandle Holiday rentals
- New Orleans Holiday rentals
- Panama City Beach Holiday rentals
- Destin Holiday rentals
- Gulf Shores Holiday rentals
- Orange Beach Holiday rentals
- Miramar Beach Holiday rentals
- Santa Rosa Island, Florida Holiday rentals
- Birmingham Holiday rentals
- Pensacola Holiday rentals
- Tallahassee Holiday rentals
- Rosemary Beach Holiday rentals
- Gulf Shores Public Beach
- OWA Parks & Resort
- Biloxi Beach
- USS Alabama Battleship Memorial Park
- Magnolia Grove Golf Course
- Waterville USA/Escape House
- Fort Conde
- The Hangout
- Alabama Gulf Coast Zoo
- The Track
- Ft. Morgan Fishing Beach
- University of South Alabama
- Fort Morgan State Historic Site
- Alabama Aquarium At The Dauphin Island Sea Lab
- Biloxi Lighthouse
- Bellingrath Gardens and Home
- Hard Rock Casino
- Golden Nugget Casino Presidential Suite
- Shaggy's Biloxi Beach
- Dauphin Island Sea Lab
- Big Play Entertainment Center
- Gulf Islands National Seashore
- Lambert's Cafe
- Alligator Alley




