Places to stay near Buffalo Museum of Science

Book unique holiday rentals, homes and more on Airbnb

Top-rated holiday rentals near Buffalo Museum of Science

Guests agree: these stays are highly rated for location, cleanliness and more.

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Superhost
Flat in Buffalo
4.84 out of 5 average rating, 274 reviews

The 2D Spot!

Buffalo's 1st official 2D Airbnb; all hand painted by local Artists. With ideal proximity to DT Buffalo, Elmwood Village & Allentown, you'll find yourself at the heart of the city's culture. Also just a 25 minute drive to the iconic Niagara Falls. Whether you're a first time visitor to Buffalo or a local seeking a unique escape, The2DSpot invites you to step inside the pages of a comic book. Immerse yourself in a world of imagination & book your stay today! Experience Buffalo like never before.

Guest favourite
A bright and airy living area features a spacious white sectional sofa, complemented by a wooden coffee table displaying a small potted plant. Large windows allow natural light to brighten the space, while a desk in the background is equipped with a computer and modern lighting.
Castle in Buffalo
4.92 out of 5 average rating, 192 reviews

Fireplace Luxury King Bed Rooftop Gym Basketball

This luxury lot offers a truly unique & romantic experience with its open concept design, soaring 16' ceiling, high-end finishes, abundant natural light. Enjoy an evening in front of the custom gas fireplace, while eating dinner/ watching movies on the 65" tv. Located in an architecturally significant building in Elmwood Village & nearby Allentown. Close to Niagara Falls, NHL & NFL venues. Larger families can be accommodated with additional bedrooms and bathrooms. Please inquire when booking.

Top guest favourite
Home in Buffalo
4.92 out of 5 average rating, 183 reviews

The Italianate: Historic Home w/ Sauna and Firepit

This beautifully restored late-1800s Victorian Italianate home offers a relaxing, centrally located retreat in Buffalo, NY, complete with a private, fenced yard containing a dry heat sauna and fire pit with complimentary firewood. Historic architectural details blend seamlessly with modern updates, including a fully stocked kitchen (coffee included). Located in the heart of Allentown, it’s an ideal stay for luxury family trips and wedding parties seeking comfort, space, and a refined home base.

Top guest favourite
A cozy back porch is illuminated by string lights, casting a warm glow over the area. A hot tub is positioned near the railing, while a wooden bench and a small table provide seating options. The house features large windows, revealing a glimpse of the inviting indoor space.
Home in Buffalo
4.96 out of 5 average rating, 154 reviews

Modern Full Home: Hot Tub, Updated Kitchen & Bath

**This is an entire home listing. There is no one else that will be at the house.** Enjoy a stylish experience at this centrally-located single family home. With an updated kitchen, a/c downstairs master BR, guest BR and attic (may-sept). Ultra modern bathroom has a walk-in shower with 2 rain shower heads, 1 extra deep bathtub, heated floor, marble counter tops & bidet Outside you will have a large back porch which includes a hot tub & string lights to enjoy during the cool Buffalo evening.

Top guest favourite
A historic garage conversion is depicted, featuring a charming blue exterior with large white garage doors and a single entrance door. Tall windows allow natural light to enter, while the surrounding greenery enhances the secluded ambiance. A concrete driveway leads up to the entrance.
Flat in Buffalo
4.98 out of 5 average rating, 290 reviews

Cozy Carriage House on Elmwood

Beautiful Airbnb inside a historic carriage house. Located directly on Elmwood Avenue but tucked back & secluded for a peaceful stay. Cozy interior with coffee bar included. The cottage’s prime location is within walking distance to many restaurants, bars, cafes, boutique shops, Delaware Park, the AKG and Birchfield Penney art museums, and more. Off-street parking allows easy access to adventure outside of the village with Niagara Falls & the Bills Stadium just a 20-30 min. drive/Uber away!

Top guest favourite
Flat in Buffalo
4.95 out of 5 average rating, 184 reviews

Peaceful Walkable 1 Queen Upper+parking+laundry

Enjoy this bright & peaceful One bedroom upper apartment located in Buffalo’s happening Westside. Great for long stays! Perfect spot for traveling professionals or couples. The apartment is a 5 min drive to downtown & Buff Gen & 10 min walk to Allen & Elmwood. The Neighborhood is pocketed with many cafes & shops and is one of Buffalo’s Garden Walk highlights. Soak in the historic architecture enjoy & delicious sourdough sandwich made by Breadhive-just a block away! LGBTQ+ POC welcome

Top guest favourite
A charming two-story home is surrounded by lush greenery and colorful shrubs. The welcoming entrance features a set of steps leading up to a front porch. Large windows allow natural light to fill the space, complemented by vibrant leaves from nearby trees.
Guest suite in Buffalo
4.99 out of 5 average rating, 276 reviews

Five Points Hideaway

Welcome to 5 Points! Offering a private, hotel room style- 1 bedroom/1 bathroom guest suite attached to a historic home in the heart of the Five Points neighborhood on Buffalo’s Westside. Private entrance. This cozy spot is perfect for an overnight or weekend visit. Mini fridge, microwave and Keurig provided. Just 8 minutes from Downtown and 25 minutes from Niagara Falls. Walking distance to great restaurants and bars. Close to Buff State, AKG, Medical Campus, Convention Center & Arena.

Guest favourite
Flat in Buffalo
4.94 out of 5 average rating, 383 reviews

Cozy Apartment in LarkinVille (Unit 2)

If this listing is not available please check out my other listings This 1st floor apartment features an open concept kitchen & living room with stove, refrigerator & microwave. A queen sleeper sofa & 54" smart TV are in the living room. The bedroom has a queen bed & dresser. The space features a In unit washer & dryer soaker jacuzzi tub and A/C mini split to help cool down the space. This is a mix use property with periment tenants as well as other guest. Noise is typically low

Guest favourite
A modern dining area features a round wooden table surrounded by four white chairs. A stylish light fixture hangs above, complemented by green accent walls. The open layout connects to a well-equipped kitchen with white cabinetry and bar seating, illuminated by natural light from surrounding windows.
Flat in Buffalo
4.87 out of 5 average rating, 253 reviews

Five Points Apartment- Upper Unit

Updated Upper Unit Apartment. Great City Location! Walking Distance to Five Points, and Lower West Side Restaurants and Shops. Off Street Parking (when available). In Unit Laundry. WiFi. Pets Allowed ($50 pet fee). Queen Bed and Fold Down Futon. Blocks from D’Youville University and minutes from Buffalo State University! Close to Kleinhans Music Hall, Elmwood Village and Allentown! 10 Min Drive To KeyBank Center - 20 Min Drive To Highmark Stadium - 20 Min Drive To Niagara Falls

Guest favourite
A bright living room features a spacious couch, accented with pillows and a warm throw. A circular mirror hangs above a decorative fireplace. Light enters through a round window, illuminating the room alongside a modern coffee table and vibrant floor cushions.
Flat in Buffalo
4.95 out of 5 average rating, 112 reviews

Cozy & Spacious Getaway! Centrally located.

Enjoy this quaint and spacious getaway located in the Elmwood Village! Walkable to shops, restaurants, museums and parks! Close to Buffalo’s best features such as Niagara Falls, Lake Erie, AGK Art Museum, Buffalo Bills and so much more! This fully renovated fourth unit is located on the third floor and offers you two bedrooms, one bath, large full kitchen, spacious living room and can sleep up to 6! This property is locally owned and maintained in pristine condition.

Guest favourite
Flat in Buffalo
4.9 out of 5 average rating, 120 reviews

Clean 2-Bedroom Apt (11 min to DT, 12 to stadium)

Keep it simple yet cozy in our comfortable, centrally-located apartment! This quiet, dead end street is nestled in the center of a vibrant, up and coming part of town. All amenities included - free street parking, WiFi, central heating, and everything you may need to make your stay a good one. We are only 11 minutes from the city, 5 minutes from the thru way, and within walking distance to many restaurants, shops and markets, parks, and a golf course!

Guest favourite
Guest suite in Buffalo
4.95 out of 5 average rating, 149 reviews

The Byrnebury Studio

Important: A few bad apples spoiled it for the bunch. Please read our house rules before booking and share them with your travel companions. This self-contained, cozy little studio is located on the second floor (need to climb stairs) of a grand home in the Parkside neighborhood. Private entrance, bath (5' x 5'), and kitchenette (6' x 8'), this studio is the perfect space for short visit to our beautiful region. (bedroom area is 12' x 12')

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