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Holiday rentals in Cerro Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Cerro Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Guest house in El Valle de Antón
4.91 out of 5 average rating, 107 reviews

The Retreat in El Valle - Casita de la Montaña

Welcome to your serene retreat in El Valle, Panama! Nestled amid lush nature, our two-bedroom casitas offer a peaceful escape with breathtaking views, exotic wildlife, and flora. Each casita features two rooms, including a queen bed, choice of king or twin beds, a small fridge, coffee station, Wi-Fi, and large terrace with comfy couch. Enjoy the shared pool, book meditation/ healing sessions, explore world-class hiking. Enjoy next door La Compania restaurants, El Valle’s famous artisan market!

Guest favourite
A private pool is surrounded by a smooth concrete deck, with gentle steps leading into the water. The adjacent open-air area features large glass doors that highlight the indoor living space, while the softly lit evening sky adds a serene ambiance.
Home in El Higo
4.97 out of 5 average rating, 33 reviews

CasAna

Fantástico lugar con espacios abiertos, luz natural y aire puro, 2 habitaciones con baño interno, terraza para recibir el amanecer y el atardecer, piscina privada que hace sentir que vuelas, mientras puedes compartir con amigos y familiares en un área grupal proporcionada por un espacioso deck, disfrutar de tus asados en la terraza y cocina equipada con todo lo que necesitas Ubicada a 10 mtos de Playa La Ermita y 12 mtos de la entrada del Valle, y a un salto del Restaurante Los Camisones.

Guest favourite
A small pool sits within a wooden deck area, surrounded by lush greenery. Steps lead from the deck to the pool, where a gentle waterfall feature adds a soothing element. Lounge chairs are positioned nearby for relaxation in a tranquil setting.
Guest house in Panamá Oeste
4.84 out of 5 average rating, 153 reviews

Cabaña de montaña con piscina privada

Disfruta de la paz y la naturaleza en esta acogedora y equipada cabaña, perfecta para desconectar y relajarte. Rodeado de bosques y con vistas espectaculares, aquí podrás respirar aire puro y contemplar las estrellas. ✔️ Ideal para parejas, familias o aventureros. ✔️ Senderos, ríos y miradores cercanos. ✔️ Espacios cómodos y equipados para tu confort. - Capacidad de 4 personas. - Posibilidad de tener 1 cama doble y 2 individuales o 4 camas individuales. - Descuento a partir de dos noches.

Guest favourite
A modern house features a prominent roof and large glass walls surrounded by lush greenery. The structure is set within a hillside landscape, with plants and stones leading to the entrance. Evening light enhances the natural beauty of the surroundings.
Home in El Valle de Antón
4.92 out of 5 average rating, 65 reviews

Entre Montañas 1 - Anton Valley

Discover the ultimate retreat in Anton Valley, where breathtaking views meet modern comforts. Relax by the fire pit under starry skies, marvel at the colorful aquarium, and soak in panoramic mountain scenery. This home is designed for unforgettable moments, offering cozy spaces, outdoor lounging areas, is a perfect stay. Whether you’re here to explore or unwind, this is your ideal escape. We are a conservative family that wants their home to be a pleasant experience for other families.

Top guest favourite
The exterior of the cabin is showcased amidst lush greenery, featuring a sloped roof and large glass windows. A wooden staircase leads up to the entrance, while a stone pathway meanders through the garden, enhancing the natural surroundings.
Cabin in Penonome
4.98 out of 5 average rating, 136 reviews

Aqeel cabin in the nature

Relax at this unique and tranquil getaway surrounded by nature. If you're lucky, you may wake up to see white-faced capuchins from your bedroom window and spot an abundance of birds, such as the crested oropendola or a toucan. The property offers river access with a sandy, beach-like area, and there is a 1 km walking trail alongside the river. With satellite high-speed internet access, you'll stay connected, though the river and sandy area may not be accessible during rainy days.

Guest favourite
A spacious bedroom is depicted, featuring a large bed with white linens and two decorative pillows. Windows adorned with navy blue curtains allow natural light in. A desk with a chair and a television is positioned nearby, complemented by wall art in muted colors.
Home in Llano Marín
5 out of 5 average rating, 29 reviews

The trip house

Enjoy the simplicity of this accommodation with the technology you need. Advantages - Quiet and Safe area - Just 500 meters from the Inter-American highway. - Near to El Machetazo Supermarket (24 hours) - Near to the Splash Kindom Water Park - Restaurants near to the residence - Wifi (100 MB) - TV with Netflix available - Smart interior lights (voice control) - 1 large bedroom with air conditioning Reservation minimum 3 hours before Check-in: 3:00 p.m. Check out: 12:00 p.m.

Guest favourite
The modern house is set amidst lush greenery, featuring a sleek design with large glass windows. An infinity pool is positioned on a spacious patio that offers unobstructed views of the surrounding hills, creating an inviting outdoor space for relaxation.
Home in Altos del Maria
4.82 out of 5 average rating, 327 reviews

Modern House with Great Views and Heated Pool

Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.

Guest favourite
Home in Altos del Maria
4.76 out of 5 average rating, 157 reviews

Villa Acuario

Relaxation is guaranteed in this one-of-a-kind glass house nestled in the lush mountains of Altos del María. Surrounded by nature and designed with floor-to-ceiling glass walls on all sides— as if you’re living inside a crystal ball. With no direct neighbors, panoramic forest views, it is perfect for a family getaway, a quiet reset, or an extended stay. The home offers light-filled interiors during the day and unforgettable stargazing nights from the rooftop.

Top guest favourite
Home in Cañaveral
5 out of 5 average rating, 16 reviews

Peaceful Garden Home |3BR| Fast WiFi|Near Penonomé

We want you to feel truly comfortable and at home. A home away from home. If you’re looking to spend quality time with family or friends, “Mi casa es su casa” at Villas de Santa María is the perfect place to relax, disconnect, and escape the noise of crowded cities. Enjoy our private garden and unwind on the terrace with stunning views of Guacamayas Hill, where you’ll experience peaceful surroundings and beautiful sunsets every afternoon.

Guest favourite
A welcoming porch area is furnished with comfortable seating and vibrant hammocks, surrounded by lush greenery and flowering plants. The structure is set against a backdrop of a clear blue sky, with sunlit grass creating an inviting outdoor space.
Home in El Valle de Antón
4.88 out of 5 average rating, 78 reviews

La Florecita - Casa de campo en Valle de Antón

Escapada acogedora en el corazón del Valle de Antón Disfruta de una estancia inolvidable en nuestra cálida y acogedora casa, ideal para familias y grupos de amigos. Ubicada en el centro del Valle de Antón, estarás a pocos minutos de mercados, restaurantes y las principales atracciones naturales. Nuestra casa combina comodidad y encanto, con espacios amplios perfectos para relajarse y disfrutar del fresco clima de la montaña.

Top guest favourite
A comfortable porch area features two colorful hammocks suspended from the walls. The polished tile flooring reflects soft light, and a pair of large wooden doors stands closed in the background. A vehicle is parked nearby, adding to the casual ambiance.
Home in Penonome
4.92 out of 5 average rating, 152 reviews

Casa cómoda, cercada y segura.

En Casa las Hamacas, disfruta de la sencillez de este alojamiento espacioso, tranquilo y céntrico. Podrás disfrutar del agradable clima penonomeño. Un lugar cerca de todo, centros comerciales, escuelas, hospital, montaña ríos y playas. Ambas habitaciones cuentan con aire acondicionado para garantizar tu descanso. A pocos minutos de la vía interamericana.

Guest favourite
A spacious living area is illuminated by natural light streaming through large glass windows. Comfortable seating arrangements are positioned around a circular coffee table, creating an inviting space for relaxation. Scenic mountain views can be seen through the glass, emphasizing the connection with the outdoors.
Cabin in Altos del Maria
4.93 out of 5 average rating, 60 reviews

Blue Sky Lodge; la mejor vista en Altos del María

Esta cabaña de lujo en la montaña ofrece un diseño moderno, acabados de calidad y vistas panorámicas de 180° de montañas y mar. Se encuentra en una comunidad cerrada segura, rodeada de un jardín verde, con amplias ventanas de vidrio que favorecen la conexión con la naturaleza. El clima es agradable, con temperaturas entre 23°C y 28°C. .

Popular amenities for Cerro Santa Cruz holiday rentals