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Holiday rentals in Panama City

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Top-rated holiday rentals in Panama City

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
Flat in Panamá
4.98 out of 5 average rating, 231 reviews

In the heart of Casco, refurbished and with parking

Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Guest favourite
A spacious balcony offers a view of greenery and the sea. A sleek white chair and a small black table are positioned to take in the scenery. A decorative plant enhances the outdoor space, while a modern vase with flowers adds a touch of elegance.
Flat in Panamá
4.97 out of 5 average rating, 34 reviews

OceanViewBalcony • RemoteWorking • Near Multiplaza

➤ Bright ✨ and beautifully decorated apartment with ocean views 🌅, a private balcony and an unbeatable location📍. 🚶🏻🚶🏻‍♀️Walk 5-10 mins to Restaurants, Supermarkets, Multiplaza Mall, Cafes 🧑🏻‍💻 Ideal for remote workers , desktop, 750 MB internet speed, 100 Up. ➤ Urban Escape - Building Highlights: ★ Gym. ★ 2 Co-Working Spaces with 500 MB internet speed. ★ Pool on the Rooftop Terrace. ➤ Located in San Francisco, Panama City | Rooftop Pool | Explore the city easily | Uber-Friendly

Top guest favourite
Flat in Panamá
5 out of 5 average rating, 12 reviews

Modern City Escape Nice Views & Great Location!

Modern and stylish apartment with an open layout and all the comforts of home. Sleeps up to four with a Queen bed in the bedroom and a sofa bed in the living area. Enjoy a fully equipped kitchen, high-speed-WiFi and A/C. Located in the heart of the city, just steps from the banking district and Via España, and close to Soho Mall, Multiplaza Mall, restaurants, cafes, pharmacies, and the metro. Perfect for business or leisure travelers seeking convenience, comfort, and a true City experience.

Top guest favourite
Apartment in Punta Paitilla
5 out of 5 average rating, 25 reviews

UrbanLuxuryintheCloudsFreeParkingclosetoeverything

Perched high above the city, this refined apartment offers a perfect blend of modern comfort and elevated style. Sunlight pours through expansive windows, revealing sweeping skyline views that feel both energizing and serene. The open living space is thoughtfully designed with clean lines, premium finishes, and a warm, inviting atmosphere ideal for relaxing or entertaining. As day turns to night, the city lights create a stunning backdrop, making this apartment a true urban retreat

Guest favourite
A cozy bedroom features a gray tufted headboard with decorative pillows, including a blue and white striped pillow. Floor-to-ceiling windows provide natural light and showcase a view of the ocean and marina. Light curtains frame the window, and a nightstand is placed beside the bed.
Flat in Panama City
4.93 out of 5 average rating, 15 reviews

Oceanview Paradise in Panama City!

Welcome to this stunning 1 bedroom, 2 bath condo in the heart of Avenida Balboa, Panama City! This property offers a fantastic opportunity for those seeking a comfortable and modern living space with a ton of amenities, while being only a short stroll away from beautiful Casco Veijo (Old Town). And an added bonus: the Sands building has a stop for the Hop on/Hop off bus for the attraction on the rooftop called "The Poin" - the zipline and rock climbing wall!

Top guest favourite
Loft in Panama City
5 out of 5 average rating, 17 reviews

Casco Viejo Dream Loft – Cozy & Central 1BR Apt

Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Casa Neuman",” this restored- colonial building and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Superhost
An inviting living area is featured, showcasing a modern grey sofa accented with decorative pillows. A round glass dining table is surrounded by chairs, and artistic wall frames complement the space. Natural light is filtered through elegantly layered window shades.
Flat in Panamá
4.91 out of 5 average rating, 138 reviews

Luxury apartment in downtown Panama, banking area

We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

Guest favourite
A modern dining area features a white table set for four, surrounded by stylish chairs. Large windows allow natural light to fill the space, revealing views of the city skyline. A sleek kitchen is visible in the background, showcasing a gas stove and granite countertops.
Flat in Panamá
4.94 out of 5 average rating, 115 reviews

k*| Delightful 1 BR w/King Bed in Calle 50

Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Guest favourite
A well-lit bedroom features a spacious bed with light-colored bedding, complemented by decorative wall art. Natural light enters through large glass doors, which open to a small terrace with greenery. A cozy armchair is positioned nearby, enhancing the room's inviting atmosphere.
Apartment in Santa Ana
4.93 out of 5 average rating, 29 reviews

King Bed, Creative Design Steps from Casco Viejo

Casco 114 is a stay created by travelers, for travelers. Located in the heart of Santa Ana, the creative district of Panama’s Casco viejo, it offers a king bed, full-size trundle, sofa bed, private terrace, washer/dryer, and unique decor. At PH Casco View: enjoy a saltwater pool, coworking space, stunning views of both the Old Town and the modern city, paid parking, and all the comforts for an unforgettable stay.

Guest favourite
Flat in Panamá
4.99 out of 5 average rating, 138 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Top guest favourite
Flat in Panamá
4.99 out of 5 average rating, 135 reviews

Sky Lounge/ APT 1 BR-vista al Mar/Pool bar & GYM

Moderno apartamento de lujo en la Cinta Costera, ideal para ejecutivos, parejas o familias. Dormitorio amplio con vista al mar, baño privado, cocina y electrodomésticos. Diseño elegante con seguridad 24/7, gimnasio, piscinas, 4 restaurantes, bar y Sky Lounge. Ubicación privilegiada cerca de supermercados y excelente oferta gastronómica en Ciudad de Panamá. PANAMA

Guest favourite
A private balcony features woven chairs and a glass-topped table. Green ferns are visible hanging from the wall, while the tiled roof of nearby buildings adds a traditional touch to the view.
Loft in Panamá
4.87 out of 5 average rating, 195 reviews

Corcho rooms #1 - queen rom with a balcony

Enjoy charming “Corcho rooms” in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant and apartments upstairs. “Corcho” is luckily situated in the central, restored part of Casco. Most of the buildings around are restored and the neighborhood is safe.

Popular amenities for Panama City holiday rentals

Frequently Asked Questions

  • What are the best places to stay in Panama City?

    Panama City has stays in vibrant neighborhoods like Casco Viejo, known for historic charm, and Punta Pacifica, often suggested for modern towers and city views. Many visitors also enjoy options around El Cangrejo for its mix of cafes and local culture.

  • What are the best things to do in Panama City with kids?

    Explore the Biomuseo’s interactive exhibits, walk the Amador Causeway for city and canal views, or visit parks like Parque Natural Metropolitano to spot wildlife. Many families enjoy boat tours or learning about the canal’s history.

  • What are some of the best things to do in Panama City?

    Wander historic streets in Casco Viejo, explore exhibits at the Panama Canal Museum, and stroll the Cinta Costera waterfront. Food and markets, canal tours, and cultural centers are frequently suggested for first-time visitors.

  • How is the weather in Panama City?

    Panama City has a tropical climate with warm temperatures year-round, often around 75–88°F (24–31°C). Visitors can expect higher humidity, with occasional rain, especially during the wet season.

  • What are the best places to visit in Panama City?

    Casco Viejo’s historic architecture, the Panama Canal, and the Biomuseo are often highlighted for visitors. The Amador Causeway is also suggested for scenic walks and views over the bay.

  • What are some hiking trails in Panama City?

    Parque Natural Metropolitano has trails through tropical forest with city vistas and wildlife. The Sendero El Gaital path and walking routes around Cerro Ancón are also frequently suggested for those who want a nature escape near urban sights.

  • What are some family activities we can do in Panama City?

    Families often enjoy the interactive displays at Biomuseo, relaxing on the Amador Causeway, and wildlife spotting in Parque Natural Metropolitano. Parks with playgrounds and canal boat tours are also popular with kids.

  • What are some of the best day trip ideas from Panama City?

    Day trips from Panama City often include hiking in nearby rainforest reserves, visiting Gamboa for canal views and nature tours, or relaxing on beaches around the Pearl Islands. Guided excursions introduce travelers to indigenous cultural sites as well.

  • Are there any pet friendly accommodations available in Panama City?

    Panama City has pet-friendly stays, especially in neighborhoods like El Cangrejo and San Francisco, where parks and walkable streets make it easy to enjoy the city with your pet. Many hosts welcome dogs and cats with advance notice.

  • What are some local tips for visiting Panama City?

    When exploring Panama City, lightweight clothing helps with humidity, and a reusable water bottle is useful. Street murals around Casco Viejo show local talent, while trying fresh seafood in city markets gives a taste of regional flavors.

  • What is Panama City known for?

    Panama City is known for the Panama Canal, mix of colonial and modern architecture, and vibrant culinary scene. Its waterfront walks and lively festivals celebrate a crossroads of cultures.

  • What are the best hidden gems to explore in Panama City?

    Panama City has tucked-away art galleries in Casco Viejo, quiet gardens at Mi Pueblito, and street food stands in Santa Ana that attract locals. Seek out small museums and indie coffee shops for a neighborhood experience.

  • What are the best foods to try in Panama City?

    Local favorites include sancocho chicken stew, patacones (fried plantains), and ceviche from city markets. Panamanian seafood, fresh tropical fruits, and pastries filled with local flavors are frequently suggested.

  • What should I bring for a trip to Panama City?

    Bring lightweight, breathable clothing for the tropical climate, comfortable walking shoes, and sun protection like hats and sunscreen. A rain jacket and an adapter for electronics are also practical for your stay.

  • What is the nightlife in Panama City like?

    Panama City has a vibrant nightlife scene, with lively rooftop bars, salsa venues, and music lounges in Casco Viejo. Neighborhoods like Calle Uruguay and El Cangrejo are known for dance clubs, craft cocktail spots, and casual pubs. Visitors often explore a mix of local rhythms and international influences after dark.

  • What are the most popular events or festivals in Panama City?

    Carnival is one of the most popular celebrations, filling Panama City with music, parades, and color before Lent. Jazz festivals, local art fairs, and folklore events also draw crowds throughout the year.

  • Are there family friendly vacation rentals in Panama City?

    Panama City has family-friendly vacation rentals, especially in areas near parks and cultural attractions like El Cangrejo, San Francisco, and Casco Viejo. Many hosts provide amenities for children and groups traveling together.

  • When is the best time to visit Panama City?

    The drier season is often recommended for clearer skies and outdoor activities. Many travelers prefer visiting when major cultural events and festivals enliven the city’s atmosphere.

Quick stats about holiday rentals in Panama City

  • Total holiday rentals

    Explore 4,860 holiday rentals in Panama City

  • Verified guest reviews

    Over 124,900 verified reviews to help you choose

  • Family-friendly holiday rentals

    1,530 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 1,800 rentals that welcome pets

  • Holiday rentals with a pool

    2,660 properties feature pools

  • Rentals with dedicated workspaces

    2,930 properties have a dedicated workspace

  • Wifi availability

    4,620 of Panama City holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Gym, BBQ grill and Laptop-friendly workspace across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)

Destinations to explore

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