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House holiday rentals in Isla Grande

Find and book unique houses on Airbnb

Top-rated house rentals in Isla Grande

Guests agree: these houses are highly rated for location, cleanliness and more.

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Superhost
A two-story wooden house is situated by the shore, surrounded by palm trees. The structure features a combination of red and white exteriors, with air conditioning units visible on the main level. A clear blue sky and lush greenery provide a vibrant backdrop.
Home in La Guaira
4.75 out of 5 average rating, 8 reviews

Hermosa Casa de Campo frente al Mar Oceanfront

Casa de Campo frente al mar en forma de barco.. donde podrás ver, escuchar y sentir los sonidos del mar de las aves y la naturaleza. Cuenta con 4 alcobas con AA de las cuales la principal tiene un delicioso balcon con vista al Mar Es un lindo lugar donde podrás disfrutar hacer senderismo, ir de pesca, pasear en bote, cabalgatas a caballo, bañarte en cascadas, en ríos y mucho más! La casa es de madera y la diseñamos como si fuese una experiencia dentro de un barco, es un lugar ideal para descans

Superhost
An open living area is showcased with a kitchenette on one side, featuring dishware and utensils arranged neatly. A spacious bed is positioned against the wall, complemented by a colorful headboard. A small wooden table is surrounded by three stools, creating a casual dining space.
Home in Portobelo
4.8 out of 5 average rating, 46 reviews

Casa Dinis, Studio, Centro de Portobelo

Relájate! estas en el Caribe! El Studio está en el centro histórico de Portobelo, pueblo Patrimonio de la Humanidad, tenéis la oportunidad de vivir una experiencia real y compartir con un pueblo lleno de historia, identidad cultural y gente linda! El Studio queda en el piso bajo de Casa Dinis y tiene una entrada independiente, cuenta con una cama Queen y un sofá cama (de preferencia para niños). El espacio es muy confortable, cocina equipada, baño, aire condicionado, Internet y Tv Bien Venidos!

Guest favourite
Two rustic-style cabins are set along the shoreline, surrounded by lush tropical trees. A wide patio is furnished with colorful chairs, offering views of the water. The natural beauty of the landscape is complemented by the tranquil waves gently lapping at the shore.
Home in La Guaira
4.97 out of 5 average rating, 105 reviews

Puntita Manzanillo, fantastic sea and jungle

Come visit one of the most unique and exclusive properties in the Panamanian Caribbean. A magical completely private 5 acre property nestled between the Caribbean Sea (500meters of ocean front) and the jungle. Surrounded by a garden of corals and visited by monkeys and macaws. Our energy is solar and we have our own aqueduct. Temperature oscillates between 72 and 84 degrees F. It is rented in its entirety. It has 3 one bedroom cabins with full baths. Satellite Internet (Starlink) is provided.

Superhost
An open-concept loft is showcased with a high, sloped ceiling and large windows that invite natural light. Comfortable seating is arranged around a glass table, while a dining area and a cozy sleeping space can be seen in the background. Nature views are visible through the windows.
Home in Santa Rita Arriba
5 out of 5 average rating, 3 reviews

The Bird's Nest in the Clouds

Escape to the Clouds: A Nature Lover’s Retreat. Welcome to The Bird's Nest, a serene loft in Santa Rita Arriba, Colón, 50 minutes from the city. Perched in the mountains, this open-concept space offers breathtaking views, fresh breezes, and the sounds of nature - rain, birds, and our chickens. Sleep with doors open, no AC. Perfect for nature lovers, not for those needing silence or climate control. Pool with breathtaking view, wifi and modern comforts included. Please read description fully.

Guest favourite
A modern exterior of a house is shown, featuring a white facade with two small, barred windows. A potted plant is positioned near the entrance, complemented by a secure front door. Soft light is emitted from two overhead fixtures, enhancing the welcoming appearance.
Home in Colón
4.89 out of 5 average rating, 9 reviews

Family style living in Colon, #2

Relax with the whole family at this peaceful place. This house is located on reverted Areas transferred back to Panamá, called Arco Iris, there’s plenty of space outside, the inside consist of a modern combination living room+kitchen, bathroom and a large bedroom with acomodación for 4 guest, the place is Airconditioned with Celling fans in the living room and bedroom. This is a second house constructed next to our first rental called, Family Style Living and close to the Panamá Canal Zone

Guest favourite
A spacious wooden chalet is positioned on a lush green slope, surrounded by tropical vegetation. The structure features an open terrace with railings, allowing for expansive views of the sky. A few palm trees and various plants complement the natural landscape.
Home in Cacique
4.96 out of 5 average rating, 24 reviews

El Paraíso

Nous avons le plaisir de vous présenter une grande maison magnifique à louer entre le village de Cacique et le village de José Pobre dans le parc national de Portobelo. Surplombant la mer des Caraïbes , nichée en pleine jungle , cette maison a un cachet unique dans la région . Son accès direct à une petite plage sauvage , dotée d’ un récif passionnant pour les fans de snorkeling en fait un lieu privilégié. Idéale pour les groupes et les familles désirant se Re- connecter avec la nature .

Top guest favourite
An outdoor terrace features a table with seating for four, framed by colorful chairs in red and blue. A hammock is suspended nearby, with the serene view of the water and distant hills providing a tranquil backdrop. Natural light illuminates the space, highlighting the coastal setting.
Home in Juan Gallego
4.96 out of 5 average rating, 49 reviews

Kasa Leilani - the perfect getaway!

Welcome to Kasa Leilani, a charming beach house nestled between the jungle and the reef in the heart of a natural park. With stunning views of the nearby Caribbean islands, this peaceful retreat offers the perfect blend of nature and comfort. Surrounded by abundant wildlife, you can relax, explore the reef, or discover the island and crystal-clear waters. Kasa Leilani provides a serene escape for nature lovers and beach enthusiasts alike, offering an unforgettable tropical getaway.

Superhost
A charming house is set amidst lush greenery, featuring a sloped tiled roof and wooden pillars. Tropical plants and vibrant flowers surround the exterior, creating a serene atmosphere that integrates with the natural landscape.
Home in Cacique
5 out of 5 average rating, 4 reviews

House in Cacique- Jungle and Sea

Finca Cacique offers a peaceful jungle escape just 5 minutes by foot from Cacique beach. This 4-bedroom house (3 with A/C, 1 with fan) is surrounded by nature and visited by monkeys, sloths, and birds. We have 2 kayaks for rent to explore nearby islands such as Isla Mamey and the Tunnel of Love. Enjoy the jungle’s beauty with the sea nearby. (Note: not beachfront property.) Perfect for nature lovers seeking tranquility and adventure.

Superhost
An aerial view captures a serene bay bordered by lush tropical greenery. A small boat is anchored in the clear waters, and a spacious house is situated near the beach, surrounded by trees and open land, creating a harmonious natural setting.
Home in Playa Blanca
4.75 out of 5 average rating, 73 reviews

Sparrow's Point

Un lugar paradisiaco que muestra al caribe panameño en su mejor esplendor!! La playa de arena blanca protegida por una bahía de aguas cristalinas y enmarcada por la selva tropical crean un idílico contraste entre el verde del follaje y el azul de la laguna. Despierte a 10 pasos del mar.

Guest favourite
The exterior of a two-story house is depicted, featuring a welcoming sign and decorative lighting. Surrounding greenery and a wooden fence provide a natural frame, while a gravel pathway leads up to the entrance. Pine trees are visible in the background.
Home in Panamá
4.75 out of 5 average rating, 8 reviews

La Colina Altos de Cerro Azul

Tendrás la oportunidad de descansar relajándote entre los sonido y la calma que la naturaleza que el lugar ofrece. El viento, los grillos y los pájaros serán parte de la experiencia. Acá podrás conectarte con la naturaleza en familia, en pareja o con amigos.

Superhost
Home in Colón
4.67 out of 5 average rating, 3 reviews

Casa entera en 4 altos Colón

Desde este alojamiento céntrico tu grupo va a tener todo al alcance de la mano. Es una casa amplia, cuanta con todo lo necesario para una placentera estadía. Lo más importante es que si tienes planes de visitar zona libre estas a pocos minutos.

Guest favourite
The image captures a serene beachfront view with gentle waves lapping at the shore. Lush palm trees line the sandy beach, leading to a charming property featuring a thatched roof. A clear blue sky provides a tranquil backdrop, enhancing the natural beauty of the surroundings.
Home in La Guaira
4.78 out of 5 average rating, 86 reviews

La casa de la guaira (Frente al mar)

Escápate a un paraíso en el Caribe Panameño en nuestra casa de playa. Diseñada para brindarte una experiencia relajante y rejuvenecedora,nuestra propiedad ofrece un equilibrio perfecto entre comodidad y naturaleza.

Popular amenities for house rentals in Isla Grande

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