
Family-friendly holiday rentals in La Mesa
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in La Mesa
Guests agree: these family-friendly homes are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for La Mesa family-friendly rentals
Family-friendly home rentals with a hot tub

Pool Side Safari Cabin (On Backside of our Home)

Guesthouse w/BALCONY!Sunset & Sunrise VIEWS~

Da Hui Hut - La Mesa’s best view and spa

Charming Suite in Historic Home

The Outside Inn at The Tipsy Goat Ranch

Nature Escape View•Sauna•SoakTub•Zoo pkg add-on

Zen Airstream Experience

Updated TownHome, Great Location, Fantastic Views
Family- and pet-friendly home rentals

Clean 1BR/1BA Guest House Peaceful Private Casita

The Queen House

Retro Fun, S'mores & Smiles in Bettie Blue

Comfy Mountain Top Casita

Former ManCave with Pool & Spa!

Cozy 2Bed-Private Parking, Dog Friendly, Big Yard!

Private cozy cottage

*NEW* Tiny home with Big features! Tiny pet ok 🐶
Family-friendly home rentals with a pool

Lovely Guesthouse in garden setting

Mountain Retreat Ocean View-Great for Staycation

The BEST NEST Clean, peaceful, private, affordable

Sunny SD l Pool l BBQ l Pool Loungers l Sleeps 10

Private Poolside Cabana

Designer Luxury Rental With Pool

Casita w/Private Pool, King Bed, Full Kitchen!

San Diego family bungalow!
Quick stats about holiday rentals that are family-friendly in La Mesa
Total rentals
260 properties
Nightly prices starting at
$64 SGD before taxes and fees
Total number of reviews
11K reviews
Pet-friendly rentals
110 properties allow pets
Rentals with a pool
80 properties have a pool
Rentals with dedicated workspaces
180 properties have a dedicated workspace
Destinations to explore
- Southern California Holiday rentals
- Los Angeles Holiday rentals
- Stanton Holiday rentals
- Las Vegas Holiday rentals
- Channel Islands of California Holiday rentals
- San Diego Holiday rentals
- Phoenix Holiday rentals
- Palm Springs Holiday rentals
- San Fernando Valley Holiday rentals
- Scottsdale Holiday rentals
- Henderson Holiday rentals
- Las Vegas Strip Holiday rentals
- Rentals with an EV charger La Mesa
- Villa rentals La Mesa
- Rentals with a hot tub La Mesa
- Fitness-friendly rentals La Mesa
- Rentals with a patio La Mesa
- Rentals with beach access La Mesa
- Rentals with a fireplace La Mesa
- Rentals with a beach view La Mesa
- Rentals with a washing machine and dryer La Mesa
- Rentals with breakfast La Mesa
- Pet-friendly rentals La Mesa
- Smoking-friendly rentals La Mesa
- Flat rentals La Mesa
- Rentals with a firepit La Mesa
- Rentals with outdoor seating La Mesa
- House rentals La Mesa
- Rentals with pools La Mesa
- Guest house rentals La Mesa
- Private suite rentals La Mesa
- Family-friendly rentals San Diego County
- Family-friendly rentals California
- Family-friendly rentals United States
- Rosarito Beach
- Oceanside City Beach
- Torrey Pines State Beach
- Pacific Beach
- Tijuana Beach
- Coronado Beach
- SeaWorld San Diego
- LEGOLAND California
- University of California San Diego
- San Diego Zoo Safari Park
- La Misión Beach
- Balboa Park
- Oceanside Harbor
- Coronado Shores Beach
- Black's Beach
- Belmont Park
- Pechanga Resort Casino
- Sesame Place San Diego
- Moonlight Beach
- Liberty Station
- Mission Beach
- Law Street Beach
- Santa Monica Beach
- Torrey Pines Golf Course