House holiday rentals in La Mesa
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Top-rated house rentals in La Mesa
Guests agree: these houses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for house rentals in La Mesa
House rentals with a pool
Home in La Mesa
4.96 out of 5 average rating, 137 reviewsHeated pool, outdoor fire pits, chef's kitchen
18–25 Aug
Home in La Mesa
4.81 out of 5 average rating, 132 reviewsSunny SD/La Mesa Updated '24-Pool-4 bed-Sleeps 10
11–18 Sep
Home in La Mesa
4.99 out of 5 average rating, 127 reviewsMid-Century Style Family House with Spa
7–14 Jun
Home in La Mesa
4.87 out of 5 average rating, 130 reviewsThe Queen House
25 Jul – 1 Aug
Home in El Cajon
4.97 out of 5 average rating, 134 reviewsBeautiful 3,000 Sq Ft Tropical Oasis
26 Sep – 3 Oct
Home in San Diego
4.9 out of 5 average rating, 116 reviewsSan Diego Getaway W/Pool & Hot tub! Sleeps 8!
28 Oct – 4 Nov
Home in San Diego
5.0 out of 5 average rating, 139 reviewsMidcentury Lux 4BR home with Pool, Spa & Cabana
1–8 Nov
Home in La Mesa
4.93 out of 5 average rating, 106 reviewsUpdated TownHome, Great Location, Fantastic Views
12–19 Aug
Weekly house rentals
Home in San Diego
4.96 out of 5 average rating, 110 reviewsBeautiful new 1 bedroom house
22–29 Oct
Home in San Diego
4.94 out of 5 average rating, 133 reviewsDesirable North Kensington+Quiet+Allergen Free
5–12 Oct
Home in La Mesa
4.95 out of 5 average rating, 111 reviewsCheery & Roomy Family Home w/Master Suite, Fence
1–8 Apr
Home in San Diego
4.91 out of 5 average rating, 157 reviewsHawk's nest - wakeup to nature - Hillcrest
24 Feb – 3 Mar
Home in San Diego
4.91 out of 5 average rating, 160 reviewsCute Small House
17–24 Oct
Home in La Mesa
4.88 out of 5 average rating, 175 reviewsPrivate cozy house
2–9 Jul
Home in San Diego
4.89 out of 5 average rating, 869 reviewsRomantic Private Canyon Retreat
26 Oct – 2 Nov
Home in San Diego
4.9 out of 5 average rating, 101 reviewsCozy 2Bed-Private Parking, Dog Friendly, Big Yard!
2–9 Oct
Private house rentals
Home in La Mesa
4.96 out of 5 average rating, 52 reviewsCozy, Single Bedroom, Detached Guest House
30 Sep – 7 Oct
Home in El Cajon
5.0 out of 5 average rating, 7 reviewsCozy 1BR Home with Lovely Front Yard
24 Nov – 1 Dec
Home in La Mesa
4.97 out of 5 average rating, 35 reviewsGarden Studio (40% long, 15% short term discount!)
9–16 Mar
Home in El Cajon
4.98 out of 5 average rating, 89 reviewsSuite Charles Way: A Cozy Fletcher Hills Studio
10–17 Aug
Home in La Mesa
5.0 out of 5 average rating, 44 reviewsEscape to tranquility: the perfect retreat
21–28 Jul
Home in La Mesa
5.0 out of 5 average rating, 23 reviewsChic and Modern Luxury Private Guest House
29 Aug – 5 Sep
Home in La Mesa
4.93 out of 5 average rating, 95 reviewsPalm Cottage San Diego
14–21 Sep
Home in El Cajon
4.93 out of 5 average rating, 30 reviewsLovely Unique Retro house with beautiful yard
6–13 Sep
Quick stats about house rentals in La Mesa
Total rentals
280 properties
Rentals with dedicated workspaces
170 properties have a dedicated workspace
Rentals with a pool
80 properties have a pool
Pet-friendly rentals
90 properties allow pets
Family-friendly rentals
190 properties are a good fit for families
Total number of reviews
9.5K reviews
Destinations to explore
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