
House holiday rentals in La Mesa
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Top-rated house rentals in La Mesa
Guests agree: these houses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for house rentals in La Mesa
House rentals with a pool

La Jolla Beach House-Family Focused-3min to Beach

Lionhead - Private Boutique Home

Bright and spacious home with views, pool & spa.

University Heights Oasis Getaway

Custom Guesthouse, Balboa Park/Zoo/Hillcrest& pool

Updated TownHome, Great Location, Fantastic Views

Oasis with ocean views/Pool/Hot tub! Sleeps 10!

Upscale Resort House /Views, Saltwater Pool/Spa !
Weekly house rentals

Escape to tranquility: the perfect retreat

Remodeled 1B/1B. Heat, Pets

Helix Haven

Jamul Hacienda | Couples Retreat | Pool & Views!

Contemporary Luxury Retreat

Hilltop luxe retreat with breathtaking views

Entire house, fenced yard, and driveway

Private House in the Hills, Pool, Pickleball court
Private house rentals

Beautiful Views with Hot Tub!

Newly Updated & Beautiful Home 5 bedrooms • 5 beds

Gorgeous Home | SPA | 15 Min Downtown

Serene Sunny Loft | Beaches | Lakes | Trails

San Diego's Finest Retreat

Lavish pool Villa In Mt. Helix, close to beaches

San Diego Retreat · La Mesa Home for 12

ModernCoastal I View I Pool ITub
Quick stats about house rentals in La Mesa
Total rentals
300 properties
Total number of reviews
12K reviews
Family-friendly rentals
190 properties are a good fit for families
Pet-friendly rentals
100 properties allow pets
Rentals with a pool
70 properties have a pool
Rentals with dedicated workspaces
160 properties have a dedicated workspace
Destinations to explore
- Southern California Holiday rentals
- Los Angeles Holiday rentals
- Stanton Holiday rentals
- Las Vegas Holiday rentals
- San Diego Holiday rentals
- Channel Islands of California Holiday rentals
- Phoenix Holiday rentals
- Palm Springs Holiday rentals
- Scottsdale Holiday rentals
- San Fernando Valley Holiday rentals
- Las Vegas Strip Holiday rentals
- Henderson Holiday rentals
- Family-friendly rentals La Mesa
- Smoking-friendly rentals La Mesa
- Guest house rentals La Mesa
- Rentals with breakfast La Mesa
- Rentals with a hot tub La Mesa
- Rentals with a beach view La Mesa
- Fitness-friendly rentals La Mesa
- Rentals with a washing machine and dryer La Mesa
- Rentals with a fireplace La Mesa
- Rentals with a patio La Mesa
- Pet-friendly rentals La Mesa
- Villa rentals La Mesa
- Rentals with a firepit La Mesa
- Rentals with outdoor seating La Mesa
- Private suite rentals La Mesa
- Flat rentals La Mesa
- Rentals with beach access La Mesa
- Rentals with an EV charger La Mesa
- Rentals with pools La Mesa
- House rentals San Diego County
- House rentals California
- House rentals United States
- Rosarito Beach
- Oceanside City Beach
- Torrey Pines State Beach
- Pacific Beach
- Tijuana Beach
- SeaWorld San Diego
- University of California San Diego
- LEGOLAND California
- Coronado Beach
- San Diego Zoo Safari Park
- Balboa Park
- La Misión Beach
- Oceanside Harbor
- Pechanga Resort Casino
- Coronado Shores Beach
- Black's Beach
- Belmont Park
- Moonlight Beach
- Sesame Place San Diego
- Liberty Station
- Law Street Beach
- Torrey Pines Golf Course
- Santa Monica Beach
- USS Midway Museum