House holiday rentals in La Mesa

An outdoor seating area is equipped with sectional sofas arranged around a fire pit, featuring a grassy lawn surrounded by lush greenery. A large tree provides shade, while a spacious porch is visible in the background, contributing to the serene atmosphere.

4.93 out of 5 average rating, 135 reviews

Family Fun! Game Garage + Big Yard + Free Parking

Embodying the epitome of cool! This home has the perfect blend of a vintage feel with a modern touch. Stepping inside, you’re greeted by an atmosphere of fun & creativity. A large private serene retreat in the backyard w/abundant seating and fire pit. Huge 3-car garage bonus space with games. Located just minutes from downtown La Mesa, many dining options & conveniences. Everything you need & more! Distance to: San Diego Zoo: 18 min Sea World: 23 min SDSU: 13 min Airport: 19 min Gaslamp: 18 min

The interior of the studio showcases a spacious layout, featuring a king size bed adorned with yellow and white pillows. A dark gray sofa complements the decor, facing a coffee table with a plant. Large glass doors provide a view of the garden and outdoor seating.

4.9 out of 5 average rating, 281 reviews

2 Bed Hidden Oasis | Garden, Laundry, Parking

Capture the essence of San Diego in our Hidden King Suite with Garden hosted by Ethos Vacation Homes. The peaceful property features elite comfort for up to 4 guests with beautiful outdoors and garden, off-street parking, A/C and heating, FREE laundry, comfortable king and queen size beds, plenty of sheets and towels, a large HDTV, Netflix, Max, Hulu, Showtime, Disney+, Apple+, and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!

4.99 out of 5 average rating, 211 reviews

An aerial view of Zen House reveals a glass solarium and inviting outdoor spaces illuminated by soft lighting. The lush garden features various plants and cozy seating. A sleek dining area is visible, all set against the backdrop of distant city lights and a twilight sky.

Home in Chula Vista

Zen Retreat with Solarium & Spa Tub

A Zen-like Airbnb, combining High Design with Leisure and Resort amenities. Self-Managed : details matter. Distant Ocean View. Close to SD landmarks; within a quiet neighborhood surrounded by canyons & parks. A blissful escape. A design that provokes a unique experience; Interior-sparkling clean. Each room unique to allow you to relax in the moment. A 2nd floor solarium offers amazing views; soak in the jacuzzi tub in an exquisite bathroom; a boutique kitchen & dining open to a sensory garden.

A contemporary casita is featured with a neatly landscaped front yard and stone pathway leading to the entrance. A garage is visible to the left, and large windows allow natural light to illuminate the welcoming exterior, which is surrounded by lush greenery.

4.92 out of 5 average rating, 103 reviews

Sunnyside Resort Spa, Beach, Zoo, Arcade

SEND US A MESSAGE FOR SPECIAL OFFER! Imagine booking the most memorable experience with your party! Kick back and relax in a safe, stylish casita. Check in contactless and enjoy! Cozy, comfy, and a perfect base for exploring the city. Cook your own meal in the alluring kitchen or enjoy your meal at the cute dining area outside. Great for family's or trips with friends! The entire guest house is is 5 minutes from SDSU, 15 minutes from the beach and 15 minutes from downtown San Diego! Enjoy

4.96 out of 5 average rating, 105 reviews

A spacious studio features a purple sofa and a queen bed, both adorned with soft blankets and decorative pillows. Vibrant area rugs cover the wooden floor. Natural light floods the room through glass doors, leading to a private patio surrounded by greenery.

Home in San Diego

XLarge Artist's Retreat w/private patio/parking

*Forget your worries in this beautiful 700sq/ft spacious and serene space. *Come soak up in the artsy feel of this newly renovated large guest suite, ideally located in the middle of town close to SDSU. Roll out of bed and Enjoy a cup of coffee in the private patio then explore ALL of the city’s top attractions a short drive away. This beautiful space is clean, crisp and fully decorated with great style uniquely curated with original art by one of SD’s most established artists. * Enjoy*

The kitchen area features modern black cabinetry and stainless steel appliances, including a microwave and compact refrigerator. A smart TV is mounted on the wall, complementing the wooden counter workspace equipped with essential cooking utensils. A dining table with two chairs is positioned nearby.

4.85 out of 5 average rating, 247 reviews

Newer "Manor Studio"

Centrally located in San Diego County this newer studio style unit has a private entrance, private patio area and street parking. Furnished with a queen size bed, love seat, full bathroom and kitchen area. One large drawer to accommodate personal items, and a wall rack to hang clothing. There is a smart TV with WiFi streaming capabilities and lots of USB plugs to charge your devices. On street parking in front of unit (no parking in driveway). No Pets allowed. No Hair Dying allowed.

A view into a modern living space reveals a sleek kitchen with bar seating and a spacious dining area. Natural light floods the room through large glass doors, showcasing lush greenery outside. A cozy area is completed with a colorful rug beneath and a inviting seating arrangement.

4.94 out of 5 average rating, 234 reviews

Cottage in the Garden! New! Modern!

COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

A welcoming living area features a spacious beige sectional sofa adorned with patterned throw pillows. Natural light filters through a large window, complemented by soft, flowing curtains. A dark ottoman with decorative details adds a contrasting element to the cozy space.

4.97 out of 5 average rating, 120 reviews

Zen Retreat: 3-Bedroom Oasis near La Mesa Village

Relax in this charming 3-bedroom, 1-bathroom home located just 1 mile from the heart of Historic Downtown La Mesa Village. Nestled in a quiet, central neighborhood, this cozy retreat offers easy access to major freeways, top-rated restaurants, and the local trolley line making it a breeze to explore the best of San Diego. Within 10 to 15 miles, you’ll find yourself in iconic destinations like Downtown San Diego, Balboa Park, Coronado Island, scenic beaches, and beautiful mountain trails.

A colorful studio space features turquoise walls and a ceiling fan. A comfortable sofa with decorative pillows is paired with a coffee table. A bed with a floral-patterned comforter sits against a window, while a TV and white refrigerator complete the modern setup.

4.98 out of 5 average rating, 307 reviews

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub

Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our studio is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions

Superhost

A neatly arranged sleeping area features a spacious bed with a textured white blanket and inviting pillows. A decorative tray holds neatly folded towels beside the bed. Soft light is provided by a lamp on a bedside table, with natural light filtering through sheer white curtains.

Home in Barrio Logan

4.85 out of 5 average rating, 292 reviews

The Pink Casita of Barrio Logan

This quaint home is central to everything San Diego. A stylish experience just minutes from Petco Park & Gaslamp! Barrio Logan, known for its art and culture, has tons of shops and restaurants just blocks away. Little Italy, Banker’s Hill, & Hillcrest are a quick Uber away! A quick 15 min drive from SAN. On site amenities include a private parking space, spacious balcony, dedicated workspace, TV & pool table! This carefully curated home will be yours away from home!

4.89 out of 5 average rating, 114 reviews

An open-concept living space is presented with exposed wooden beams and ample natural light. A modern kitchen island features bar seating, while a dining area awaits with a long table. Cozy seating is arranged in the adjacent living room, framed by large windows overlooking greenery.

Home in Allied Gardens

Cozy Mid Century Modern

Cozy Mid-Century Modern | Central, Family-Friendly & Inviting Inside you’ll find a bright, open-concept layout with natural light and cozy. Whether you’re relaxing in the living room, cooking in the fully equipped kitchen, or enjoying meals together in the dining area, the home is designed to make every moment comfortable and effortless. My goal is simple: you arrive as guests and leave feeling like family. I’m here to make your stay easy, relaxing, and memorable.

4.93 out of 5 average rating, 136 reviews

Palm Cottage, San Diego

Palm Cottage sits in the heart of La Mesa Village, San Diego. Enjoy the charm of a historic home with a fully remodeled and stylish interior featuring both Dutch & French doors letting in plenty of sunshine. A large private yard w/ covered outdoor living area creates the ultimate indoor/outdoor lifestyle. You're steps from the local grocery store, village shopping, coffee shops, restaurants, bars and the trolley. You could not ask for a better location!

Popular amenities for house rentals in La Mesa

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

House rentals with a pool

5 out of 5 average rating, 202 reviews

A serene backyard is framed by colorful sunset skies, featuring a cozy hammock in the foreground and a comfortable seating area with grey couches. String lights add warmth to the outdoor space, complemented by lush greenery throughout the neatly landscaped yard.

Home in La Jolla

La Jolla Beach House-Family Focused-3min to Beach

4.85 out of 5 average rating, 103 reviews

The private pool area is surrounded by palm trees and cacti, with lounge chairs positioned for relaxation. A shaded dining area is visible in the background, complemented by the warm glow of a sunset sky. The scene creates a serene outdoor retreat.

Home in San Diego

Surf Cottage w/Pool & Firepit 10min from the beach

Superhost

A serene outdoor space features a salt-water pool surrounded by a concrete patio and manicured grass. An umbrella provides shade over the poolside area, with lush greenery and mountains visible in the background under a partly cloudy sky.

Home in Lake Murray

4.88 out of 5 average rating, 215 reviews

Bright and spacious home with views, pool & spa.

4.81 out of 5 average rating, 128 reviews

The outdoor area showcases a clear pool surrounded by a spacious patio. Lounge chairs, a poolside table, and an umbrella are positioned for relaxation. The backdrop features low landscaping with cacti and a glimpse of the house, enhancing the tranquil setting.

Home in Lake Murray

Mid-Century Modern and Contemporary House

4.93 out of 5 average rating, 131 reviews

A living room features a luxury hanging chair suspended from the ceiling. Natural light filters through sheer curtains, illuminating a cozy seating area with a plush sofa and wooden coffee table. A 50” television is mounted above an elegant fireplace, enhancing the room's comfort.

Home in City Heights

Designer Luxury Rental With Pool

A scenic hillside is displayed, featuring a variety of homes nestled among lush greenery. The landscape showcases a blend of residential architecture within a mountainous region, with expansive views of the surrounding area under a clear blue sky.

4.93 out of 5 average rating, 124 reviews

Updated TownHome, Great Location, Fantastic Views

4.99 out of 5 average rating, 174 reviews

A bright living space features a warm wooden ceiling and large windows. A comfortable orange sofa is paired with a wooden coffee table on a patterned area rug. The kitchen, visible in the background, includes modern appliances and white cabinetry, enhancing the cozy atmosphere.

Home in Hillcrest

Custom Guesthouse, Balboa Park/Zoo/Hillcrest& pool

4.96 out of 5 average rating, 189 reviews

A dining space features a round table with four white chairs, complemented by a potted plant. Large glass doors slide open to reveal expansive views of the backyard, pool, and surrounding hills, with soft evening light illuminating the scene.

Home in Spring Valley

Upscale Resort House /Views, Saltwater Pool/Spa !

Weekly house rentals

5 out of 5 average rating, 26 reviews

A cozy outdoor seating area features two white Adirondack chairs positioned beside a small round table. The inviting entryway of the tiny home is visible, surrounded by lush greenery and trees, creating a peaceful and refreshing environment.

Home in Rolando

Tiny Home with a View

5 out of 5 average rating, 13 reviews

BIG Modern Mt Helix Home with Pool

4.98 out of 5 average rating, 197 reviews

The craftsman bungalow is framed by lush landscaping and palm trees. A welcoming porch features a swing, while solar panels are visible on the roof. The structure combines traditional and modern elements, with a combination of earthy tones and textures enhancing its unique architectural style.

Home in Normal Heights

Cali-Craftsman | 3BR | Central | New Backyard | AC

4.92 out of 5 average rating, 60 reviews

A modern kitchen features sleek white cabinetry and stainless steel appliances. A spacious island with seating for four is highlighted by pendant lighting. Light-colored wood flooring complements the overall design, while two windows allow natural light to brighten the space.

Home in Spring Valley

Bonita Main House 3 Bedroom/ 1 Bath

5 out of 5 average rating, 19 reviews

Airbnb Luxe: Designer Pool, Fitness and Office

The living room is furnished with a comfortable loveseat and a coffee table, complemented by a white TV stand supporting a large smart TV. Decorative plants and slender white branches enhance the ambiance, while soft lighting is provided by a standing lamp. Framed artwork adorns the walls.

4.98 out of 5 average rating, 60 reviews

Discover La Mesa: Your Perfect Cozy Base

4.95 out of 5 average rating, 19 reviews

Helix Haven

A modern living space is highlighted with a comfortable gray sofa adorned with vibrant cushions. A textured golden coffee table is positioned in front of the sofa, topped with a game and a decorative bowl. Natural light floods the area, drawing attention to the art on the walls.

4.98 out of 5 average rating, 42 reviews

25% off •Hot tub•BBQ•Patio•4 min SDSU•CentralSD

Private house rentals

5 out of 5 average rating, 21 reviews

The exterior view of the home displays a warm-toned facade with a welcoming front door. A pathway of pavers leads to the entrance, bordered by mulch. Grass is maintained around the patio area, which features a compact seating arrangement with a small table and chairs.

Home in El Cajon

Cozy 1BR Home with Lovely Front Yard

4.96 out of 5 average rating, 28 reviews

Serene Sunny Loft | Beaches | Lakes | Trails

5 out of 5 average rating, 13 reviews

A sunlit bedroom features a spacious queen bed adorned with decorative bedding and a light throw. A minimalist bench sits at the foot of the bed, while a desk and lamp occupy a corner. Windows provide natural light, illuminating the soft-toned walls.

Home in El Cajon

Cozy quiet getaway, great mattress (1-br)

5 out of 5 average rating, 70 reviews

A modern kitchen features green cabinetry and a spacious island with seating. Stainless steel appliances and a window above the sink provide natural light. Open shelving displays kitchen essentials, while a door leads to the outside, enhancing accessibility.

Home in San Diego

San Diego's Finest Retreat

Superhost

A modern kitchen features sleek black cabinetry and stainless steel appliances. A spacious countertop provides ample prep area, while stylish open shelving displays decorative items. Soft natural light filters in through a window, highlighting a patterned rug on the floor.

4.62 out of 5 average rating, 21 reviews

Modern, Private, & Stylish Home

A spacious living room features a large sectional sofa with orange accent pillows, complemented by a round coffee table. An island with bar stool seating is visible, along with modern kitchen appliances. Natural light enters through the nearby window, highlighting the warm wood tones of the decor.

4.98 out of 5 average rating, 84 reviews

Cozy Mid-Century Charmer | Huge Backyard | Firepit

A modern living room features a sleek black sofa set arranged around a low coffee table. A large television mounted above a black stone fireplace provides entertainment. Natural light streams through expansive windows, highlighting views of the surrounding landscape.

4.93 out of 5 average rating, 27 reviews

Luxury Hilltop Getaway • Scenic Views