Guest house holiday rentals in La Mesa
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in La Mesa
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in La Mesa
Family-friendly guest house rentals
Guest house in La Mesa
4.66 out of 5 average rating, 158 reviews(1) Downstair Apartment La Mesa, Mt Helix Area
Guest house in La Mesa
4.74 out of 5 average rating, 221 reviewsSan Diego/Mt. Helix Two Bedroom
Guest house in La Mesa
4.86 out of 5 average rating, 138 reviewsCozy Casita
Guest house in San Diego
4.99 out of 5 average rating, 366 reviews*Private Canyon Retreat: Your Own Guesthouse*
Guest house in San Diego
4.97 out of 5 average rating, 295 reviewsPrivate Guest House with a View
Guest house in San Diego
4.97 out of 5 average rating, 510 reviewsCentral & Serene Secret Garden Guesthouse
Guest house in Chula Vista
4.95 out of 5 average rating, 477 reviewsPrivate Casita in Great Eastlake Neighborhood
Guest house in San Diego
4.96 out of 5 average rating, 254 reviewsYour Kensington Bungalow
Guest house rentals with a patio
Guest house in La Mesa
4.84 out of 5 average rating, 122 reviewsPrivate Studio with Panoramic View
Guest house in San Diego
4.99 out of 5 average rating, 111 reviewsModern Guest House with Patio, Parking, & Laundry
Guest house in Lakeside
4.94 out of 5 average rating, 103 reviewsSky Mesa-Adorable Cottage on the Hill
Guest house in San Diego
4.98 out of 5 average rating, 102 reviewsStunning Patio! King Bed, Walkable, Games, Parking
Guest house in San Diego
4.93 out of 5 average rating, 125 reviewsModern Guest House with pool, steps to SDSU
Guest house in Spring Valley
4.97 out of 5 average rating, 114 reviewsLoft Cabin-Night Cinema+Hot Soaking Tub+Views!
Guest house in San Diego
4.92 out of 5 average rating, 155 reviewsCentral studio w/ private outdoor space & parking
Guest house in La Mesa
4.97 out of 5 average rating, 119 reviewsSan Diego Newly Built Private Guesthouse (Sleep 5)
Guest house rentals with a washing machine and dryer
Guest house in El Cajon
4.99 out of 5 average rating, 153 reviewsModern mountain guest house. Incredible views
Guest house in San Diego
4.91 out of 5 average rating, 115 reviewsCharming Granny Flat Near SDSU & Transit Center
Guest house in San Diego
4.9 out of 5 average rating, 196 reviewsSTUNNING Casita with a View!!
Guest house in San Diego
4.95 out of 5 average rating, 120 reviews1BR Casita in the Heart of Kensington!
Guest house in La Mesa
4.92 out of 5 average rating, 256 reviewsPrivate Detached Modern Studio located in La Mesa
Guest house in San Diego
4.98 out of 5 average rating, 188 reviewsNorth Park Garden Retreat Casita
Guest house in San Diego
4.83 out of 5 average rating, 214 reviewsCozy Casita
Guest house in Lemon Grove
4.89 out of 5 average rating, 168 reviews"Glam Farmhouse dream cottage"🏠🌠
Quick stats about guest house rentals in La Mesa
Total rentals
60 properties
Wifi availability
60 properties include access to wifi
Rentals with dedicated workspaces
30 properties have a dedicated workspace
Pet-friendly rentals
10 properties allow pets
Total number of reviews
3.9K reviews
Nightly prices starting at
$67 SGD before taxes and fees
Destinations to explore
- San Diego Holiday rentals
- Palm Springs Holiday rentals
- Anaheim Holiday rentals
- Joshua Tree Holiday rentals
- Los Angeles Holiday rentals
- Beverly Hills Holiday rentals
- Santa Monica Holiday rentals
- Malibu Holiday rentals
- Santa Barbara Holiday rentals
- Las Vegas Strip Holiday rentals
- Las Vegas Holiday rentals
- Phoenix Holiday rentals
- House rentals United States
- Guest house rentals United States
- House rentals San Diego
- Guest house rentals San Diego
- Guest house rentals California
- House rentals California
- Guest house rentals Palm Springs
- House rentals Palm Springs
- House rentals Anaheim
- Guest house rentals Anaheim
- Pet-friendly rentals La Mesa
- Rentals with an EV charger La Mesa
- Rentals with a washing machine and dryer La Mesa
- Rentals with a patio La Mesa
- Rentals with beach access La Mesa
- Rentals with a firepit La Mesa
- Rentals with outdoor seating La Mesa
- Smoking-friendly rentals La Mesa
- Monthly Rentals La Mesa
- Rentals with pools La Mesa
- Fitness-friendly rentals La Mesa
- Rentals with a fireplace La Mesa
- Rentals with a beach view La Mesa
- Private suite rentals La Mesa
- Family-friendly rentals La Mesa
- Family-friendly rentals La Mesa
- House rentals La Mesa
- Rentals with a hot tub La Mesa
- Flat rentals La Mesa
- House rentals San Diego County
- Guest house rentals San Diego County
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom