Guest house holiday rentals in San Diego County
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in San Diego County
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in San Diego County
Family-friendly guest house rentals
Guest house in San Diego
4.93 out of 5 average rating, 447 reviewsPrivate Cottage in Walkable North Park w/AC
4–11 Jun
Guest house in Vista
4.88 out of 5 average rating, 241 reviewsPRIVATE CASITA nestled in a great neighborhood
14–21 May
Guest house in San Diego
4.97 out of 5 average rating, 292 reviewsPrivate Guest House with a View
6–13 Aug
Guest house in San Diego
4.91 out of 5 average rating, 355 reviewsLa Casita - Fully Updated Casita in Mission Hills
18–25 Oct
Guest house in San Diego
4.97 out of 5 average rating, 506 reviewsCentral & Serene Secret Garden Guesthouse
16–23 Oct
Guest house in San Diego
4.94 out of 5 average rating, 333 reviewsThe BEST NEST Clean, peaceful, private, affordable
20–27 Feb
Guest house in La Mesa
4.92 out of 5 average rating, 205 reviewsFig Tree Bungalow
22–29 Jun
Guest house in San Diego
4.9 out of 5 average rating, 877 reviews"Granada House" North Park Urban Cottage
1–8 May
Guest house rentals with a patio
Guest house in La Mesa
4.98 out of 5 average rating, 250 reviewsLa Mesa Suite
7–14 Apr
Guest house in San Diego
5.0 out of 5 average rating, 106 reviewsSantorini-Inspired Cottage #1 w/ Hot Tub + Views
23–30 Dec
Guest house in La Mesa
4.97 out of 5 average rating, 130 reviewsDa Hui Hut-Beachy home/La Mesa’s best view and spa
13–20 Sep
Guest house in San Diego
4.99 out of 5 average rating, 151 reviewsAdorable cottage in Talmadge
4–11 Aug
Guest house in San Diego
4.92 out of 5 average rating, 148 reviewsCentral studio w/ private outdoor space & parking
7–14 Dec
Guest house in San Diego
4.98 out of 5 average rating, 123 reviewsPrivate Studio Cottage with Outdoor Patio
1–8 Jan
Guest house in Oceanside
4.94 out of 5 average rating, 154 reviewsDetached, Private Cottage! Fenced, PET friendly!
21–28 Jan
Guest house in La Mesa
4.99 out of 5 average rating, 167 reviewsSDCannaBnB #1 *420 *parking *dog-friendly *hot tub
Guest house rentals with a washing machine and dryer
Guest house in Valley Center
4.91 out of 5 average rating, 210 reviewsNorth San Diego Serenity
23–30 Oct
Guest house in San Diego
4.91 out of 5 average rating, 114 reviewsCharming Granny Flat Near SDSU & Transit Center
6–13 Jun
Guest house in La Mesa
4.99 out of 5 average rating, 133 reviewsStunning Guest House 15 min. from Zoo, Downtown
26 Sep – 3 Oct
Guest house in Encinitas
4.96 out of 5 average rating, 347 reviewsCardiff by the Sea Beach Bungalow
30 Mar – 6 Apr
Guest house in San Diego
4.9 out of 5 average rating, 191 reviewsSTUNNING Casita with a View!!
13–20 Oct
Guest house in San Diego
4.98 out of 5 average rating, 117 reviewsCasita Hermosa - Close to everything in San Diego
23–30 Oct
Guest house in San Diego
4.9 out of 5 average rating, 477 reviewsUrban Chic Guesthouse with Private Patio
3–10 Sep
Guest house in San Diego
4.95 out of 5 average rating, 107 reviewsRelax in a Centrally Located, Modern Guest House
30 Dec – 6 Jan
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