
Holiday rentals in La Mesa District
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Top-rated holiday rentals in La Mesa District
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Beachfront Family EcoParadise to Coiba lsl BunkBed
Experience authentic Panama in our family-owned 30-hectare private tropical beachfront paradise. Accessible only by boat (30-min ride from Pixvae or 1:30hr from Santa Catalina). Gateway to Coiba Island, our remote bay offers pristine jungle, diverse wildlife, and breathtaking views. Enjoy kayaking, fishing, and guided eco-tours. Spot howler monkeys, sloths, and rare birds. Savor fresh tropical fruits and local cuisine. Perfect for nature lovers, photographers, and digital nomads (WiFi available)

Casa de Campo en Olá, ríos, cascadas, Los Picachos
Finca La Terapia hace honor a su nombre, se encuentra entre las montañas del pintoresco pueblo de Olá de Penonomé, en la cual podrás desconectarte del ajetreado día a día de la ciudad. Cuenta con 42 Hectáreas privadas para explorar la naturaleza. El distrito de Olá, se caracteriza por tener lo mas hermosos paisajes Naturales entre los que podemos mencionar, Los Chorros de Olá, Chorros las Mesitas, Cerros los Picachos, Rio San Antonio, Balneario Brujas, entre otros a muy poco minutos de la Finca.

North Villa with Rooftop. Full Kitchen!
Fly / Drive - Tour Coiba - Relax at the North Villa! The North Villa has plenty of space. The rooftop patio has furniture, a bar and is perfect for star gazing and birdwatching. Your villa comes with ample bedrooms, fully equipped kitchen (cookware, spices, blender, coffee maker etc), full living area, charcoal grill, covered parking and dedicated Internet. We offer a free ground shuttle if you fly into the local airstrip. Feel free to message us and learn how to skip the 6hr+ drive!

Casa a minutos de Santiago, U Latina, HospChichoF.
Casa amplia, cómoda y totalmente equipada en una ubicación estratégica de Santiago.Perfecta para todo tipo de huéspedes: familias, viajeros de trabajo, estudiantes, personas que vienen a citas médicas o quienes buscan un espacio tranquilo y accesible. La casa está ubicada muy cerca del Hospital Dr. Chicho Fábrega, Clínica Norte, U.Latina, Oxford School, Comercios Supermercados, farmacia, ,restaurantes, y minutos de Santiago centro. Un lugar seguro para estadías cortas y de larga estancia.

Ginger
During your stay at Adama Eco Farm you will enjoy a 360° nature experience. In front of the natural pool, in the shade of the jungle you can easily connect to the silence, the earth, the sound of the birds and the clear air. Our Farm is located 5 minute’s drive from the unique surfing beaches of Santa Catalina. Our cabins are a combination of wood with caña Blanca. Each cabin has a fan, double bed and two sofas open into single beds. Shower, toilet and fully equipped kitchen.

Private Villa & Pool, in Lago Bay, Santa Catalina
A beautiful stand-alone 60 sq mt villa, 1 King bed and 1 queen. King size bed in the master bedroom with black out drapes, Queen size bed and fold out couch in the loft area. Full kitchen, living and dining area, flat screen TV, Bathroom with soaps/shampoos, and rainfall showerhead. Large terrace with views as far as the eye can see, with BBQ, dining table and outdoor sectional sofa. Private swimming pool with seating area, pool lounge chairs, lighted gazebo and sun umbrellas.

Mountain retreat
Our beautiful, modern, comfortable house is designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and also a base to explore the area which is in a beautiful part of Panama near a cloud forest national park with amazing hiking to waterfalls and local communities. The house is large, sleeping 12, within 17 acres of forest with rivers for swimming. We can arrange tours and hosted retreats for yoga, cooking and more.

Peaceful home w/ spacious living & office area
Spacious and peaceful home in a safe area of Santiago. 4 bedrooms (ideal for families and groups), bright living-dining area and large kitchen to share with family or friends, plus a private office for working comfortably. High-speed Wi-Fi, air conditioning and fans in all rooms, fully equipped kitchen, washer/dryer, and safe for valuables. Self check-in with smart lock, parking for several cars, and a coffee station with board games and karaoke.

Amazing Cozy Villa Overlooking the Pacific Ocean
Disfruta de nuestra espectacular Villa, rodeada de tranquilidad con un hermoso paisaje, conectada con la naturaleza y perfecta para desconectar de la vida cotidiana; un lugar encantador para compartir con tu familia o amigos. Cuenta con todas las amenidades necesarias para que su estadía sea inolvidable y una piscina exclusiva para disfrutar de la hermosa vista al Océano Pacífico.

Cabaña del Sol en Finca Namuiki by the River
Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

k* Casa Matilde | 2BR Santa Fe Retreat by River
Escape to Casa Matilde, a renovated 100 m² home in Santa Fe de Veraguas. With 2 bedrooms and 3 beds (1 queen & 2 twins), it’s perfect for families or remote workers. Enjoy a bright living room, modern bath with hot water, A/C, and fast Starlink Wi-Fi. Relax by the private creek, explore the river just 200 m away, and take in mountain views—all with total privacy and comfort.

Mansion en Granja Orgánica Piscina Climatizada
Relájate con toda la familia y amigos hasta 30 personas en esta acogedora casa en una granja organica con animales, sembradios, pesca de tilapia, café , rios, contamos con piscina Climatizada, terraza techada de 120 mts para que celebres tus ocasiones especiales.
Popular amenities for La Mesa District holiday rentals
Other great holiday rentals in La Mesa District

Charming 1-Bedroom Beachfront Hotel With Pool

BLUE FROG Santa Fe Home with a View

Cómodas habitaciones en Santiago

Turismo Rural -Casita de Campo-El Copé- Las Yayas

Cabaña Entre Pinos y Montañas En Chepo, Herrera

La Yeguada - Forest Point Cabin

Deluxe Family Room

Apartamento amueblado Aguadulce
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