Holiday rentals in Melrose

Three Bedroom House on Private Scenic Lake Mable

Located on pristine (no gas engines) swimming and fishing Lake Mable, this cheerful home is the perfect spot for a fun filled family vacation or just a relaxing weekend getaway. Enjoy the peaceful sounds of nature as you sit and watch the sunset over the lake, roast some marshmallows over the firepit, or just relax by the lake with a fishing rod in hand. You may see Sandhill Cranes, Red-headed Woodpeckers, or even a few deer. Let your worries drift away and enjoy the tranquility around you.

Tranquil Lakehouse with Private Access

Welcome to a boater’s dream retreat in Melrose. Tucked inside a quiet cove, this peaceful lake escape is protected from wind and noise while offering incredible access for fishing and water sports. Launch from the private boat ramp, tie up at two docks, and clean your catch on site. This 3-bedroom, 2-bath home sits just 3 miles from Historic Downtown Melrose and is within easy driving distance of Gainesville. Perfect for families, anglers, and guests seeking a relaxed lakeside stay year-round.

Modern LAKE HOUSE on Lake Santa Fe near Gville/UF

Have fun OR relax at this fully renovated LAKE HOUSE w/BOATHOUSE and raised sunset deck only 30 mins to Gainesville! Sit back and and enjoy the beautiful views of the lake as soon as you enter the home or up close from the hammock swings in the boat house! 3 BR/2 BA plus converted air conditioned garage used as a game room with Ping Pong Table and TV, easily sleeping 8. The backyard offers a large deck with privacy fencing and lush landscaping with direct access to step right into the lake.

Charming Lakefront Log Home

Welcome to your perfect lake retreat! Located on a no public access lake. This charming log home has a private dock and boat ramp suitable for launching your boat for fishing or skiing. There are kayaks on premises for use. This is an ideal location to enjoy North Florida’s lake life with family, friends, or work retreat. Includes a fully stocked kitchen, covered porch, fire pit, gas grill, and WiFi if you feel the need to plug in. NOT suitable for parties or events. NO loud noise, please.

Modern Cottage on Private Spring Fed Lake

Nestled on a gorgeous spring-fed private lake in the woods, our charming cottage is your ideal retreat. Whether you're dreaming of peace and quiet, a romantic getaway, or fun with your kids, this is the place to be! Kayak around the serene lake as you witness breathtaking sunsets, take a dip in the cool water or simply unwind amidst the beautiful surroundings. As night falls, gather around a fire and gaze up at the many stars lighting the sky. Come and create many cherished memories ☀️

The Orchid of Lake Santa Fe

Melrose Bay on Lake Santa Fe This apartment is newly remodeled. It features new cabinets, new appliances, a private porch and lovely furnishings, WIFI and cable. Downtown Melrose is in walking distance with three restaurants (one is the famous Blue Water Bay), public library, post office, grocery store, dollar store and Ace. Bring your boat and launch at the nearby boat ramp. Lake Santa Fe is a recreational lake with clean spring fed water for swimming, boating, skiing and fishing.

The Maple Lake House

Enjoy a peaceful stay in the Maple Lake House far away from the noise and bustle of the city. This cozy home is nestled amongst live oaks and long leaf pine trees while overlooking beautiful Mandarin Lake. The home was designed and built by a local author and family friend, Marilyn Maple. Our family purchased and restored her home long after her passing, adding our own artistic flair. We hope you will enjoy our serene and peaceful home, sharing the love of its beauty as much as we do.

Lakefront A-Frame · Hot Tub + Fire Pit · Dock

Our beautifully renovated A-frame sits on a quiet private lake in the heart of Melrose. Enjoy peaceful surroundings, modern finishes, and plenty of outdoor fun: relax in the hot tub, fish from the shore, paddle the lake with our pedal boat, or gather around two fire pits under the stars. Inside, you’ll find an open layout, lake views, and a fully equipped kitchen. Conveniently located near Gainesville, Ocala, St. Augustine, and natural springs—perfect for family and friends!

The Nest on Lake Santa Fe in Melrose, FL

The Nest is a beautiful two-story cottage on Lake Santa Fe. Enjoy some peace and serenity, catch monster bass, or bring your ski boat for high-speed fun. We are located just 20 minutes from Gainesville and UF. The Nest is great for a weekend getaway or a week of peaceful relaxation. We do not allow parties or events out of respect for our neighbors and we allow a maximum of 6 guests (max 4 adults). Absolutely no animals are allowed on the property at any time for any reason.

Gator Trail Guesthouse

Slow mornings, quiet evenings, and adventure whenever you crave it. This quaint lakeside hideaway is your home base for exploring North Florida — whether you’re here for a Gators game, a beach day, or a stroll through St. Augustine. Nestled in peaceful Swisher Lakes Estates, you’ll feel secluded and surrounded by nature, yet only a short drive to Gainesville, Jacksonville, Crescent Beach, and more. Kick back, breathe deep, and make memories by the water.

Lakefront Retreat Apartment Remodeled, Premium Bed

Private lake home on Big Lake Santa Fe is the perfect place to unwind and enjoy gorgeous sunset views. The rental unit is an upstairs separated apartment. It has a cedar interior with a cabin feel that has been renovated with new appliances, flooring and updated bathroom with walk in shower. Bring your boat to cruise the lake or fish and tie up at our dock. Enjoy swimming, water skiing, fishing or just relaxing on the deck.

Harmony Oaks Guesthouse on Lake McMeekin

Enjoy a great getaway at Lake McMeekin. Ours is a beautiful spring fed lake with beautiful sunrises. A private dock with table and chairs is part of the package. Our guesthouse provides a spacious, comfortable, quiet, lake retreat in the country with 30 minutes of Gainesville, Ocala and Palatka. Bring a kayak or canoe... or some fishing equipment and fish off the dock or enjoy the area's many fishing lakes and springs.!