
Hotels in Mission Bay
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Top-rated hotels in Mission Bay
Guests agree: these hotels are highly rated for location, cleanliness and more.

Join a yoga class or hit the onsite putting course
The Lanai Garden Premium room with two queen beds offers 460 square feet of upgraded comfort, featuring a patio with serene garden or lagoon views. Thoughtful amenities include high-speed internet, a mini-refrigerator, coffee maker, and a modern bathroom with a bathtub/shower combination. Select rooms may include a walk-in closet, wet bar, or preferred location for added luxury. Nestled among lush resort landscaping, this non-smoking room is perfect for a relaxing San Diego escape.

The Davis Downtown San Diego | Full Room
Discover the charm of The Davis Downtown, where historic 19th-century architecture meets the vibrant energy of East Village. Enjoy cozy rooms filled with San Diego sunshine, stunning city views from the rooftop lounge, unbeatable proximity to Petco Park, the Gaslamp Quarter, and the city's best restaurants, bars, cafés and entertainment just steps away! Our tech-enabled rooms offer self check-in at 4pm, 24/7 guest support by text and a Virtual Front Desk accessed via mobile device.

Stylish San Diego Downtown Marriott Suite
In the center of the action, Marriott Vacation Club, San Diego is a true escape that will greet you with a perfect blend of historic ambiance and contemporary design. Inspired by San Diego's renowned Gaslamp Quarter, many of the 264 well-appointed suites feature stunning San Diego views and atmospheric wood and metal finishes. Enjoy this sleek, sophisticated setting to unwind from a day of exploration and recharge before venturing out to experience San Diego's amazing nightlife

Former 1924 YMCA, beautifully reimagined
The Guild Hotel offers 162 thoughtfully designed rooms and suites, including 12 lavish suites and a penthouse with a private rooftop. Each space blends modern comfort with luxurious touches, featuring bespoke furnishings like rose gold lighting and leather tufted headboards. Nostalgic design elements meet innovative, future-forward amenities for a truly refined stay. Enjoy a unique and calming retreat within this beautifully reimagined historic building.

Staypineapple at Hotel Z
This room features a luxurious king size bed and high speed WiFi for unlimited devices so you can stream your favourite shows on the 43 inch HDTV with ease. Enjoy the naked experience with European style double duvets oversized fluffy towels and luxury linens. Relax in micro fiber bathrobes with French terry lining and indulge in Tommy Bahama bath products. Start your day with a Keurig coffee and complimentary bottled water for a truly refreshing stay.

Ocean View Private Room at Surf Hostel
Enjoy a stay at ITH San Diego Beach Bungalow Surf Hostel in Pacific Beach. Our oceanfront hostel has a large deck overlooking the beach. You can enjoy our private rooms and all the amenities of our communal spaces. Our community space includes Communal Kitchen Oceanview Deck Coworking Space Indoor Lounge Coin Laundry Daily Social Events Free Cook it Yourself Pancake breakfast is offered each day. We rent surf board for your learn how to surf!

Beachfront Location! Water Activities Onsite!
Our beachfront property is not only conveniently situated near the airport, but it also offers breathtaking views of the ocean. Whether you're interested in exploring the vibrant Port of San Diego or embarking on a cruise from the B Street Cruise Ship Terminal, this is the perfect place to start your seaside adventure. Additionally, you'll find world-class attractions such as the San Diego Zoo and USS Midway Museum just a short drive away.

Stay Classy Hostel - Downtown - Solo Pod
Stay Classy Hostel is in downtown San Diego, just minutes from the Gaslamp Quarter, Petco Park, and the Convention Center—only 2 blocks from the Park & Market Trolley Station. We offer clean, modern, and affordable shared rooms with hotel-style comfort. Enjoy memory foam beds with privacy curtains, fast Wi-Fi, secure PIN entry, and stylish common areas. Perfect for travelers looking to relax, connect, and explore. Stay Classy.

2BR Top Floor Suite • Free Parking - Conv Center
FREE Parking + Walk to the Convention Center Stay in the heart of Downtown San Diego — just minutes from the San Diego Convention Center, Gaslamp Quarter dining, Petco Park, and the waterfront. The rare bonus? Free overnight parking is included for one vehicle. Whether you're visiting for a conference, business trip, or weekend getaway, this professionally managed boutique suite offers location, comfort, and simplicity.

2BR • Walk to Convention Center • Free Parking
FREE Parking + Walk to the Convention Center Stay in the heart of Downtown San Diego — just minutes from the San Diego Convention Center, Gaslamp Quarter dining, Petco Park, and the waterfront. The rare bonus? Free overnight parking is included for one vehicle. Whether you're visiting for a conference, business trip, or weekend getaway, this professionally managed boutique suite offers location, comfort, and simplicity.

Studio • Free Parking • Walk to Convention
FREE Parking + Walk to the Convention Center Stay in the heart of Downtown San Diego — just minutes from the San Diego Convention Center, Gaslamp Quarter dining, Petco Park, and the waterfront. The rare bonus? Free overnight parking is included. Whether you're visiting for a conference, business trip, or weekend getaway, this professionally managed boutique suite offers location, comfort, and simplicity.

The Sofia Hotel
Unwind in a non-smoking room with a plush king bed, air conditioning, and modern amenities like a workspace, microwave, refrigerator, and cable TV. Special suites offer extra touches, including fine linens, ambient lighting, and elegant decor. Every detail blends Sofia signature charm with comfort and style, ensuring a memorable stay.
Popular amenities for Mission Bay hotels
Family-friendly hotels

1-Bedroom Hotel Suite - 2 beds

Queen Bed | Super 8 San Diego | Close to SD Zoo

Downtown San Diego Stay Near Gaslamp Quarter

ComicCon ‘26-San Diego July 21-26, 2026 (5 nights)

Machronicles Properties at Gaslamp Plaza Suites

At the heart of Gaslamp District

Close to Airport | Dining. Balcony & Pet-Friendly

Diamond Head Inn
Hotels with a pool

Kayak & SUP eco tours of Mission Bay

Iconic Resort in San Diego

Comic-con in the heart of San DiegoJuly 21-25

Poolside dining at Tropics Cantina (main pool)

Playful escape near games & concerts at Petco Park

San Diego Marriott Studio

Check out the activity calendar to see what’s on

Cruise around on bikes or claim a poolside lounger
Hotels with a patio

Spacious 1 BR@ Mission Valley Worldmark

Modern King Room | Luxe Stay in Little Italy

WorldMark Inn at the Park

Club Wyndham Harbour Lights

Inn At The Park 1 Bedroom Suite

Comic-Con 2026: Spacious King Suite + Sofa Bed

Inn at the Park Studio

Nice Property, stay right in SD!
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