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Boutique hotels in Missouri

Find and book unique boutique hotels on Airbnb

Top-rated boutique hotels in Missouri

Guests agree: these boutique hotels are highly rated for location, cleanliness and more.

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Guest favourite
Hotel room in Hermann
4.92 out of 5 average rating, 103 reviews

Crown's Flower Suite, Live Music, Right Downtown!

Hermann 1837 Cellar Bar/Restaurant Onsite. Live Music Nightly May-Oct! It’s a Floral Delight in Our Flower Suite. A 2nd Floor Suite Filled with Flowers! Complete with Prints, Framings, and Collectibles Celebrating Flowers. King Bed, Electric Fireplace, Microwave, Mini Fridge, WiFi, & Cable. $20 Personalized All Day Shuttle Service (Trolley is $30). Free Pick Up/Return to Train Station & Free Electric Charging Stations. $50 per pet nightly fee. Free Drink Tickets & Free Buffet Breakfast.

Top guest favourite
The room features a queen size bed adorned with a decorative red and gold coverlet. Two windows are dressed with plush maroon curtains. A dresser with a mirror and a TV are positioned against one wall, while a faux fireplace adds warmth to the inviting space.
Hotel room in Osceola
4.93 out of 5 average rating, 115 reviews

Historic Commercial Hotel(1868),Sally Rand Suite

The Historic Commercial Hotel (Est.1868) on the Downtown square in beautiful Osceola,Missouri. Old world feel with modernized accommodations. The Historic Commercial Hotel has numerous themed rooms which are designed and named after past historical guests. This specific room is "The Sally Rand Suite". Named after past historical guest Sally Rand ( 1904 – 1979) who was an American burlesque dancer and Silver Screen star, most noted for her ostrich feather fan dance and balloon bubble dance.

Guest favourite
The spacious common area features an open kitchen with a dark granite countertop, blending modern functionality with historic charm. Two large stained glass windows cast colorful light throughout the room, while a grand staircase leads to an upper level, showcasing the building's architectural elegance.
Hotel room in St. Louis
4.98 out of 5 average rating, 61 reviews

Luxury Retreat, Hot Tub,En-Suite Bath, Location+

Discover refined elegance in The Riverfront Suite, where Gothic grandeur meets contemporary comfort. This distinctive retreat showcases original stained glass windows and exotic wood finishes . A plush queen bed and ambient electric fireplace create an intimate atmosphere, while the luxurious en-suite bathroom features heated floors, designer tile work, and a 2-person soaking tub. Take in panoramic city views from the shared rooftop hot tub. Perfect for couples seeking a romantic escape.

Guest favourite
A spacious interior features a four-poster bed with ornate detailing, complemented by elegant bedding. A seating area is visible with a light-colored sofa. Dark wood furniture, including a large armoire, enhances the room's historic charm. Crystal light fixtures add a touch of sophistication.
Hotel room in Excelsior Springs
4.97 out of 5 average rating, 61 reviews

Beautiful Historic Suite

The Hope Loft Suite, located on the second floor of Casa Di Vite International Wine Café," in Excelsior Springs, Missouri, offers a delightful place to stay. This exquisitely furnished loft is crafted to reflect the style of the early 1900s, featuring a generous king-size bed and an additional room with a twin-size bed. Its location in historic downtown Excelsior Springs ensures easy access to diverse dining choices and shopping experiences. A private staircase in the back offers access.

Guest favourite
A charming building features a stone exterior with vibrant red doors. Two small sitting areas are adorned with red chairs and a table, surrounded by a lush green plant. A wooden fence lines the property, with a clear blue sky overhead.
Hotel room in Springfield
4.98 out of 5 average rating, 102 reviews

“The Classic” at Rockwood Motor Court on Route 66.

Rockwood Motor Court, built in 1929, is located on historic Route 66. Each room is themed and furnished to the era of Route 66. “The Classic” showcases the automobiles on road in the 1940’s and 50’s. This room features vintage furniture, a full size bed, bathroom with dressing area, and corner shower. Renovated in 2019, enjoy a clean, comfortable room and experience authentic motor court lodging. Need more space? We also have larger rooms and can package multiple rooms for your group.

Guest favourite
Hotel room in St. Louis
4.98 out of 5 average rating, 48 reviews

Chic Ultramodern Studio Loft w/ Designer Features

The Nash Loft is a stunning minimalist studio with 12’ ceilings + bright 7’ industrial steel-frame windows, a spacious open layout, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, an Edison-illuminated community courtyard, and a fully-equipped kitchen with black stainless appliances and quartz countertops. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Top guest favourite
The room features exposed brick walls and a wooden ceiling, enhancing the rustic charm. A spacious bed sits beside a cozy seating area with an orange armchair and a guitar. Natural light floods in through multiple large windows, with decorative elements like a cowhide rug and artwork adding character.
Hotel room in Hannibal
4.97 out of 5 average rating, 156 reviews

The Woodsman Suite

A third floor suite, facing the river with the train tracks only a couple blocks away. It took 2 months to do the ceiling. Carefully polished and placed the old lath in a specific design, the ceiling is a work of art. Eighty percent of the material used in this room is from re purposed lumber, either from this building or from a childhood barn built in the late 1800's. It will take you a while to notice every detail down to the toilet paper holder which is from an old barn post.

Top guest favourite
A well-lit room features a spacious bed topped with white bedding and pillows. A flat-screen TV is mounted on the wall opposite a large mirror, enhancing the sense of space. A sleek bathroom area is visible, showcasing modern fixtures and marble flooring.
Hotel room in Washington
4.94 out of 5 average rating, 125 reviews

River Sirens Hotel Junior Suite

11 Room Boutique Hotel in beautiful Downtown Washington. Each room has: Private Entrance Guest Access - Key Pad, Free Parking, King Size bed, TV, Wifi, Hair Dryer, Individual A/C & Heat. Guests can enjoy a shower room featuring a changing area with separate vanity and water closet spaces. Each room is also equipped with a full kitchen featuring large refrigerators with ice dispensers, induction stove top, microwave, toaster, and coffee station.

Guest favourite
Hotel room in Branson
4.81 out of 5 average rating, 202 reviews

Lavender Paradise: Room #26 at The Bradford

Come enjoy a relaxing stay at The Bradford! Easy access to the Branson Strip and only 5 minutes from Silver Dollar City! Our rooms are newly remodeled, and each have their own uniqueness. The complimentary coffee bar and game room are everything you need before a fun-filled day in Branson! There’s no other view of the Branson strip quite like The Bradford’s! You won’t want to leave this charming, one-of-a-kind property.

Guest favourite
Hotel room in Springfield
4.94 out of 5 average rating, 66 reviews

Culture Boutique Hotel: Casablanca Suite.

Our loft-like suites feature furniture made from reclaimed materials from our building, a converted mattress factory. Each suite is inspired by a city in Eurasia. The rooms boast high ceilings, a 39in tv, a refrigerator, microwave and a V60, Electric Kettle, + complimentary coffee from Eurasia Coffee Co. This room (Casablanca) boasts a jacuzzi and separate shower.

Guest favourite
A porcelain clawfoot soaker tub is situated against a textured, gold-hued wall. The tub features elegantly designed legs and a handheld shower attachment, providing a classic touch to the relaxing space.
Hotel room in Washington
4.88 out of 5 average rating, 198 reviews

430 West Front: Balcony Riverfront View

This room is located on the second floor over our quaint wine bar with a private balcony overlooking the Missouri River. Enjoy a cup of coffee or glass of wine from our wine bar on your private balcony. Just steps from our Historic downtown riverfront community with plenty of bars, restaurants, and charming shops to explore.

Superhost
A spacious bedroom features a comfortable bed with crisp white linens. Natural light enters through a large window adorned with sheer curtains. A wooden table stands nearby, while a ceiling fan adds cooling circulation to the air.
Hotel room in Branson
4.73 out of 5 average rating, 120 reviews

Cozy Boutique #17 by Silver Dollar City Economy

Our rooms were designed with your needs in mind. Comfortable with a bit of personality, each one of our rooms will make your stay at Mandalay relaxing and fun. Mandalay | Modern Comfort Motel

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