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Holiday rentals in Panama Canal

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Panama Canal

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
Flat in Panamá
4.98 out of 5 average rating, 226 reviews

In the heart of Casco, refurbished and with parking

Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Guest favourite
Flat in Panamá
4.71 out of 5 average rating, 7 reviews

Modern and cozy downtown apartment with a unique rooftop

VIVE Y DISFRUTA una experiencia única en el corazón de la ciudad de Panamá, apartamento moderno, acogedor y totalmente equipado. Su ubicación estratégica y céntrica te permitirá moverte fácilmente y conocerTODO LO MEJOR DE PANAMA. restaurantes, centros comerciales, supermercados, farmacias, hoteles y principales atracciones turísticas, todo a minutos. Ideal para tour, trabajo remoto o estadías cortas y largas. Aquí encontrarás comodidad, diseño, vistas espectaculares y una estadía inolvidable.

Top guest favourite
A charming apartment building is nestled among lush greenery and tall trees. The exterior features a welcoming porch with railings and is surrounded by tropical plants, creating a serene environment. Natural sunlight filters through the leaves, highlighting the vibrant foliage.
Guest house in Gamboa
4.94 out of 5 average rating, 80 reviews

Gamboa Toucan Apartment casa # 126

Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

Top guest favourite
Flat in Panamá
5 out of 5 average rating, 8 reviews

Modern City Escape Nice Views & Great Location!

Modern and stylish apartment with an open layout and all the comforts of home. Sleeps up to four with a Queen bed in the bedroom and a sofa bed in the living area. Enjoy a fully equipped kitchen, high-speed-WiFi and A/C. Located in the heart of the city, just steps from the banking district and Via España, and close to Soho Mall, Multiplaza Mall, restaurants, cafes, pharmacies, and the metro. Perfect for business or leisure travelers seeking convenience, comfort, and a true City experience.

Top guest favourite
A communal rooftop space is revealed, showcasing several white-accented chairs and small tables arranged amidst potted plants. The backdrop features a panoramic view of the Panama City skyline against a clear blue sky.
Flat in Panamá
5 out of 5 average rating, 57 reviews

Tropicool Loft w/rooftop steps from Casco

This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftops, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fast internet, and great AC. You’re also directly in front of the Cinta Costera park for running, biking, tennis courts. Near local airport for flights to Bocas!

Superhost
A modern living and dining area is showcased, featuring a white dining table set for four. A cozy sofa with colorful cushions is positioned next to a large window, allowing natural light to fill the space. Stylish decor, including a piece of wall art, enhances the ambiance.
Serviced apartment in Panamá
4.84 out of 5 average rating, 140 reviews

Yoo Panama 36th floor waterfront apartment

Elegant, comfortable, modern and luxurious apartment located in the best building in Panama, with ocean views from the 36th floor. It has the best social areas designed by renowned designer Philippe Starck. Fully furnished to make your stay a unique experience. The building has a gym, swimming pool, play areas for adults and children, squash court, 3 excellent restaurants, and a supermarket. Located in a privileged location in the heart of Panama's financial center.

Guest favourite
Flat in Panamá
4.86 out of 5 average rating, 22 reviews

Casco Viejo / Penthouse w/ Terrace & Pool Access

Nuestro Penthouse, en el último piso de La Cuadra Residence, en Casco Antiguo, cuenta con terraza privada con vista al Océano Pacifico y su entrada al Canal de Panamá, Cerro Ancón, Casco Antiguo, Cinta Costera, Biomuseo, Puerto de Cruceros de Amador y el skyline de la hermosa Ciudad de Panamá. Contamos con acceso privado al área social y piscina, desde nuestra terraza. Nuestro Lobby cuenta con acceso privado al restaurante Ayala Vida, de autentica comida panameña.

Top guest favourite
Flat in Panamá
4.96 out of 5 average rating, 23 reviews

Gorgeous Flat in the best location in Casco Viejo

This cute and stylish studio is perfectly located in the heart of Casco Viejo, Panama City’s most charming historic district. Recently renovated, it combines modern comfort with classic charm inside a beautiful colonial building—just steps from top restaurants, bars, monuments, and attractions. The space includes a comfortable sofa bed, making it ideal for a couple or a small family looking to enjoy the vibrant atmosphere of Casco right outside their door.

Top guest favourite
A modern living space features a light-colored sofa facing a wall-mounted television. A round dining table with four chairs is positioned nearby. Large windows offer views of the cityscape, while natural light brightens the room. The elegant flooring complements the contemporary design.
Flat in Panamá
5 out of 5 average rating, 24 reviews

New apartment in the heart of Panama

Comfort, location and tranquility in new accommodation, in the financial center of Panama, close to Calle 50 and the emblematic El Tornillo building. All modern amenities, close to hotels, casinos, restaurants and with a completely safe area to walk. Swimming pool and gym on the top floor with spectacular city views. Easy access: from the airport Metro or land terminal you can reach the station via Argentina located 400 meters from the apartment.

Top guest favourite
Flat in Panamá
5 out of 5 average rating, 12 reviews

Private parking & rooftop | Studio Casco Center

This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Guest favourite
A modern pool area is surrounded by lush greenery, featuring tall palms and ornamental plants. The pool is designed with a minimalistic white edge, reflecting the vibrant blue sky above. Natural light illuminates the serene outdoor space, creating a refreshing atmosphere.
Flat in Panamá
4.75 out of 5 average rating, 321 reviews

Casa Arias with Pool, Rooftop and Great Location 2

Welcome to Casa Arias, your retreat in the heart of the Old Town! A cozy bedroom for two, with a fully equipped kitchen and a view of a spectacular pool surrounded by tropical vegetation. Access to a shared rooftop terrace with panoramic views of the Old Town, ideal for relaxing or sharing good times. The property offers tropical design, comfort, and privacy. Enjoy an unforgettable stay in a cozy and fully equipped environment.

Guest favourite
A rooftop terrace features a wooden hot tub surrounded by potted plants and a stone pathway. In the background, historical ruins are visible, complementing the vibrant atmosphere of the area. Seating areas and greenery contribute to a relaxing outdoor space.
Flat in Panamá
4.94 out of 5 average rating, 99 reviews

Beautiful apartment in Casco Viejo ST. George D

Welcome to our spacious and charming apartment in Casco Viejo. Located in a vibrant and historic neighborhood. You will love the warm atmosphere created by the lime and pebble walls, in perfect harmony with our modern and elegant decor. The space is large and comfortable, ideal for relaxing after a day exploring the city. As a host, I'm available 24/7 to answer questions and make sure you make the most of your stay.

Popular amenities for Panama Canal holiday rentals

Destinations to explore

  1. Airbnb
  2. Panama
  3. Panama Canal