Holiday rentals in San Lorenzo District

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in San Lorenzo District

Guests agree: these stays are highly rated for location, cleanliness and more.

%{current} / %{total}1 / 1

Top guest favourite

A spacious living area features a comfortable sofa and two accent chairs surrounding a striped area rug. Floor-to-ceiling windows offer panoramic views of the ocean and surrounding islands, while a flat-screen TV is positioned on a low console for easy viewing.

Villa in Boca Chica

4.96 out of 5 average rating, 103 reviews

Sand Dollar Villa by the sea at Boca Chica Panama

Sand Dollar Villa by the sea This beautiful, very private retreat boasts panoramic views and direct access to a beautiful beach and sheltered bay. Located in Boca Chica, it is only 45 minutes from Panama’s second largest city, David. From your doorstep, you can enjoy island hopping in an archipelago of unexplored islands, or you can choose to soak in the sun on your very own private beach. Sand Dollar Villa offers the perfect décor for gracious living and entertaining in a magical setting!

Top guest favourite

A modern kitchen space is featured with a large island topped with granite. Black padded stools are positioned at the island. The cabinetry combines light and dark finishes, with stainless steel appliances visible. A dining area with a wooden table and decorative accents creates a functional setting.

Home in David

5 out of 5 average rating, 19 reviews

Disfruta David! Casa 3 rec. cómoda mejor ubicación

Este alojamiento es ideal para viajes en grupo hasta 6 y maximo 8, Casa totalmente remodelada, acabados de lujo, cocina completa, con Isla, 3 recamaras, 1, camas King, 1 Queen, 1 Tween y sofá cama doble, 3 baños, 2 de ellos en las recámaras, closets y W. Closet. en recamara principal. estacionamiento con portón eléctrico. lugar tranquilo y residencial. Apropiado para paseos en familia o grupos. Cerca de vía Panamericana en David, cerca de Plaza Las Terrazas, transporte público muy cerca .

Top guest favourite

A private outdoor area features a pool surrounded by stone tiles and a covered seating area. Sun loungers are positioned under an umbrella, with views of green landscape and water in the background. The setting provides a serene atmosphere for relaxation.

Home in Playa Hermosa

5 out of 5 average rating, 44 reviews

Entire house with private pool facing beach !

Astonishing views, bird sounds & howler monkeys, Our region is designated by Panama as a Natural Water Preserve with 23 islands, lots of snorkeling, whale watching and beachcombing! One of the top best sport fishing destinations in the world! Casa Tanamera has a large garden set amidst the jungle. it boasts a plunging view on the beach and its entire bay area. the house is large enough for 4 persons, has large bedrooms and bathroom, a large patio with its dining, BBQ and lounge area.

Superhost

A pathway flanked by vibrant tropical plants leads to an entrance. The wooden walkway is bordered by low greenery and lit by soft, glowing lights. The landscape reflects a serene outdoor environment, complemented by clear blue skies above.

Tiny home in Alto Boquete

4.81 out of 5 average rating, 171 reviews

A 10 min Boquete I Cabaña Rio Vista 2-Cafe gratis

🌿 Cabaña Nueva en Boquete – Naturaleza y vistas espectaculares • 🌊 Acceso directo a un hermoso río natural • 🌄 Acceso a miradores con vistas panorámicas impresionantes •• 🍳 Estufa eléctrica (sin horno) y cafetera • 🌬️ Clima fresco de Montaña • 📍 A 2 min de la vía David–Boquete • 🐶 Máximo 2 perros pequeños permitidos • 🚗 Último tramo de piedra (auto pequeño pasa sin problema) • 🫒 Café, azúcar, sal, pimienta, crema y aceite de oliva de cortesía • 🕒 Check-in 3 pm | 🕛 Check-out 12 md

Top guest favourite

A spacious room is visible through an open door, featuring a double bed with clean linens and a simple design. Natural light illuminates the area. A handcrafted wooden bench is placed in front of the bed. A potted palm adds a touch of greenery to the setting.

Guest suite in David

4.97 out of 5 average rating, 506 reviews

CasaMonèt

Suite con entrada independiente: estacionamiento techado, cama doble, baño sanitario, cocineta y escritorio. Tu espacio personal en el corazón de David. Cuenta con aire acondicionado tipo split, abanico de techo, TV con acceso a netflix, internet wifi gratis, cortinas black out, tanque de reserva de agua, agua caliente, cocineta equipada con estufa eléctrica, refrigerador, cafetera, microondas y utensilios básicos. No cuenta con lavandería, generador eléctrico y aislamiento acústico.

Guest favourite

Home in Los Algarrobos

4.94 out of 5 average rating, 163 reviews

Acogedora y relajante casa con terraza

Relájate con toda la familia en este tranquilo lugar, a solo 10 minutos del centro de David y 25 minutos del turístico Boquete. Muy cerca encontrarás centros comerciales, restaurantes y servicios, pero lo suficientemente alejado del bullicio de la ciudad. Un espacio seguro, cómodo y lleno de detalles para que disfrutes tu estadía. Casa segura con 3 recámaras, terraza estilo Café-Bar, patio con asador y gazebo, aires acondicionados y todas las comodidades para disfrutar tu estadía.

Guest favourite

A welcoming cabin is shown with a covered porch featuring colorful hammocks and a small wooden chair. Soft lighting illuminates the entrance, while surrounding greenery and cultivated plants complement the natural setting.

Cottage in Caldera

4.89 out of 5 average rating, 161 reviews

Acogedora casa de campo en Caldera, Boquete.

Relájate con toda la familia en este tranquilo lugar para quedarse y disfrutar de la naturaleza, hermosos ríos, pozos termales, cascadas, senderismo, buen clima, con acceso a mini comercios locales y restaurantes típicos del área, terraza para hacer BBQ y mucho mas! Es un lugar super tranquilo, con una vista encantadora. Cabaña de una recámara con cama Full, Un Sofá cama grande. Cocina, equipada. Baño con agua caliente. Estacionamiento bajo techo. Recientemente WIFI. 👌

Guest favourite

A wooden cabin with a sloped roof is set amidst a lush green landscape. A well-maintained lawn features decorative plants and trees, while a pathway leads to the entrance. Large glass doors reveal a glimpse of the interior space.

Cabin in Alto Boquete

4.84 out of 5 average rating, 258 reviews

Las cabañas del francés - Nature & comfort

Descubra nuestro complejo de 6 cabañas de madera, equipadas con cocina, cama king y dos individuales en el altillo. Disfrute de una vista espectacular al barranco y un entorno natural impresionante. Estamos a 15 min de Boquete y 25 min de David en carro, lo que permite disfrutar de la tranquilidad sin alejarse de la ciudad. Áreas comunes con piscina y barbacoa para momentos inolvidables. Viva una experiencia única, combinando confort moderno y naturaleza en armonía.

Guest favourite

A spacious bed is centered in a room with vibrant green walls. Decorative pillows are arranged neatly on the gray bedding, complemented by a bedside table with a lamp. Art featuring a flower and a hummingbird adorns the wall above the bed.

Bungalow in Boca Chica

4.94 out of 5 average rating, 79 reviews

Finca Colibri

Ein moderner Bungalow mit einmaligen Blick auf die Mangroven von der Bucht Bajia de Muerte, die im Herzen eines Naturschutzgebietes liegt. Der Bungalow ist sehr privat und ruhig gelegen. Zum nächsten Strand sind es nur wenige Autominuten. Es erwarten dich eine voll ausgestattete Küche, ein modern eingerichtestes Panorama Bad und ein sehr bequemes King Size Bett. Auf Anfrage können wir auch Bootsfahrten zu den Inseln, Yoga sowie Reit und Angelausflüge organisieren.

Superhost

A spacious living area features large windows allowing natural light to flood the space. A blue sofa is complemented by decorative pillows. Textile art in various shades of blue adorns the walls. A wooden table with chairs is positioned for dining or relaxation, with greenery visible outside.

Villa in San Lorenzo District

4.85 out of 5 average rating, 20 reviews

Villa Turquesa with sea view in Isla Boca Brava

Welcome to Villa Turquesa, a true hidden gem on the stunning Boca Brava Island. This tropical retreat blends luxury, comfort, and adventure—all with spectacular ocean views. It accommodates up to 8 guests, features a fully equipped kitchen, shared pool, free WiFi, and easy access to Playa Las Cocas, just a 25-minute walk from the villa, as well as trails where you can spot birds and howler monkeys. Book Villa Turquesa now and let the sea breeze do the rest!

Guest favourite

The property features a spacious beachfront villa, framed by lush palm trees and open grass areas. A vibrant red roof contrasts with the white exterior, and the shimmering ocean is visible in the background, providing a serene coastal atmosphere.

Home in Playa Nanzal

4.86 out of 5 average rating, 37 reviews

Private Beachfront Getaway

Forget your worries in this spacious and serene space. Its seclusion is its charm. Escape from the busy city of David and kick back in our private beachfront property! There are little to no lights nearby, making for extraordinary sunsets/sunrises and star gazing. Whether you are a family looking to get away in the summer, a group of friends celebrating a birthday, or just looking for a break from life, this is the spot.

Guest favourite

Cabin in Boquete

4.93 out of 5 average rating, 14 reviews

Cabaña en Alto Boquete 2

Bienvenidos a Cabañas Piedra del Risco. Nuestras cabañas fueron diseñadas para ofrecer el equilibrio perfecto entre lo moderno y lo rural. Desde la terraza verás el majestuoso Volcán Barú y el cañón del río Caldera, estarás rodeado de naturaleza y la tranquilidad única de Boquete. Estamos a solo 12 minutos del centro de Boquete, lo suficientemente cerca para explorar, y lo bastante lejos para desconectar.